Product Details
Place of Origin: EZHOU, CHINA
Brand Name: DESHENG
Certification: ISO9001:2008
Model Number: CAPS
Payment & Shipping Terms
Minimum Order Quantity: 10g
Price: Negotiable
Packaging Details: Plastic bottle/Ctn Box
Delivery Time: 1-3 days
Payment Terms: L/C, D/A, D/P, T/T, Western Union, MoneyGram
Supply Ability: 1000kg/Month
Name: |
CAPS Buffer |
Full Name: |
3-Cyclohexylaminopropanesulfonic Acid |
Apperance: |
White Crystal Powxer |
CAS#: |
1132-61-2 |
Molecular: |
C9H19NO3S |
Molecular Weight: |
221.32 |
Category: |
Good's Buffer |
Application: |
PH Adjustment |
Field: |
Bioscience |
Industry: |
Medical & Health |
Name: |
CAPS Buffer |
Full Name: |
3-Cyclohexylaminopropanesulfonic Acid |
Apperance: |
White Crystal Powxer |
CAS#: |
1132-61-2 |
Molecular: |
C9H19NO3S |
Molecular Weight: |
221.32 |
Category: |
Good's Buffer |
Application: |
PH Adjustment |
Field: |
Bioscience |
Industry: |
Medical & Health |
CAS 1135-40-6 CAPS Biological Buffer 3-Cyclohexylaminopropanesulfonic Acid
Application of biological buffer CAPS
CAPS, also known as 3-cyclohexylaminopropanesulfonic acid, is a biological buffering agent. It is white crystal or powder in appearance. CAPS can be dissolved in water. The pH buffer range is 8.9-10.3. The PKA value is 9.6 and the molecular weight is 243.28 at 25℃. The CAS number is 1135-40-6. CAPS has a wide range of applications, including DNA/RNA extraction kits, PCR diagnostic kits, biochemical diagnostic kits, manufacturing welding materials, air conditioning equipment, manufacturing metal lithium, new coatings, new industrial materials, etc.
Brief introduction
Full Name | N-Cyclohexyl-3-aminopropanesulfonic acid | Molecular weight | 221.32 |
Abbreviation | CAPS | Molecular formula | C9H19NO3S |
CAS No | 1135-40-6 | ENIECS | 214-492-1 |
Appearance | White crystal powder | Purity | ≥99% |
In nucleic acid extraction, it can be combined with 3-[(3-cholamidopropyl)dimethylammonium]-1-propanesulfonate (CHAPS), 3-(cyclohexylamino)-2-hydroxy-1- Propanesulfonate (CAPSO), 2-(cyclohexylamino)ethanesulfonate (CHES), etc. are used together to prepare a solution for nucleic acid hybridization. It can reduce the yield of non-specific hybrids and increase the specificity of nucleic acid hybridization, while maintaining the yield of target hybrid products. It has important value in the identification of specific pathogens, the diagnosis of genetic diseases, and the analysis of gene sequences.
CAPS can be used in various environment-friendly high-quality water-based two-component polyurethane coatings. It can coexist stably with resins containing active genes (hydroxyl, carboxyl, amine, epoxy, etc.) for a long time at room temperature. The application of CAPS in coatings is widely used in the water-based coatings market. In addition, CAPS and aliphatic polyisocyanates can react under mild conditions and in the presence of tertiary amine neutralizers, and the resulting sulfonic acid urea derivatives are very good emulsifiers.
CAPS in capillary electrophoresis analysis, CAPS can be used to prepare the running buffer (background electrolyte solution) in capillary electrophoresis, as a terminating electrolyte, which can realize the electric booster online enrichment of 2-nitrobenzoic acid and 3-nitrobenzoic acid Set and separate. The CAPS buffer is suitable for running buffers for high molecular weight proteins (greater than 20KD). If it is a low-molecular-weight protein blotting experiment, Tris+Glycine is generally used, and Tris-Tricine+EDTA is used to exclude glycine in protein sequencing.
CAPS can also be used in biochemical diagnostic kits, DNA/RNA extraction kits and PCR diagnostic kits, as a buffer for enzymatic chemistry and HPLC separation of alkaline drugs. It is widely used in the transfer process of protein sequencing. CAPS is used as a western blot transfer buffer or transfer buffer. CAPS can also support alkaline phosphatase activity and inhibit the growth of Aeromonas at a pH of 10.5. After adjusting the pH to 11.0 in deionized water, it is used for the purification of fibronectin. In addition, CAPS is also used as the eluent in cation exchange chromatography to manufacture welding materials, air-conditioning equipment and manufacturing raw materials. It can also be used to make fireworks, used as analytical reagents, heat exchange carriers, and also used in the pharmaceutical industry, air conditioning, pyrotechnics, dry batteries and other applications.
Application of biological buffer CAPS
CAPS, also known as 3-cyclohexylaminopropanesulfonic acid, is a biological buffering agent. It is white crystal or powder in appearance. CAPS can be dissolved in water. The pH buffer range is 8.9-10.3. The PKA value is 9.6 and the molecular weight is 243.28 at 25℃. The CAS number is 1135-40-6. CAPS has a wide range of applications, including DNA/RNA extraction kits, PCR diagnostic kits, biochemical diagnostic kits, manufacturing welding materials, air conditioning equipment, manufacturing metal lithium, new coatings, new industrial materials, etc.
Brief introduction
Full Name | N-Cyclohexyl-3-aminopropanesulfonic acid | Molecular weight | 221.32 |
Abbreviation | CAPS | Molecular formula | C9H19NO3S |
CAS No | 1135-40-6 | ENIECS | 214-492-1 |
Appearance | White crystal powder | Purity | ≥99% |
CAPS white crystalline powder
Buffer capacity of 3-(cyclohexylamine)-1-propanesulfonic acid buffer solution:
Adding a small amount of strong acid or alkali to the buffer solution will not change the pH value of the solution much, but if the amount of acid and alkali is large, the buffer solution will lose its buffering effect. This shows that its buffer capacity is limited.
The buffer capacity of the buffer solution is related to the concentration of the components that make up the buffer solution. The buffer solution composed of 0.1mol·L-1HAc and 0.1mol·L-1NaAc has a greater buffering capacity than the buffer solutions of 0.01mol·L-1HAc and 0.01mol·L-1NaAc. This point can be confirmed by calculation. But the concentration of the components of the buffer solution should not be too high, otherwise, the effect between ions cannot be ignored.
When the ratio of the two components of the buffer solution is not 1:1, the buffering effect is reduced and the buffering capacity is reduced. When c (salt)/c (acid) is 1:1, the △pH is the smallest and the buffering capacity is large. Whether for acid or alkali, it has a greater buffering effect. The pH value of the buffer solution can be calculated by the following formula:
At this time, the buffer capacity is large. The farther the ratio of the buffering components is from 1:1, the smaller the buffering capacity, and it may not even play a buffering role. For any buffer system, there is an effective buffer range, which is roughly within one pH unit on each side of pKaφ (or pKbφ).
Weak acid and its salt (weak acid and its conjugate base) system pH=pKaφ±1
Weak base and its salt (weak base and its conjugate acid) system pOH=pKbφ±1
For example, the pKaφ of HAc is 4.76, so HAc and NaAc are suitable for preparing a buffer solution with a pH of 3.76 to 5.76, which has a greater buffering effect in this range. The buffering capacity is the largest when preparing a buffer solution with pH=4.76, at this time (c(HAc)/c(NaAc)=1. 3-(cyclohexylamine)-1 propanesulfonic acid has a wide range of uses, 3-cyclohexylaminopropanesulfone Acid (CAPS) is relatively stable in nature, with a pKa value of 10.4 at 25°C and a pH buffer range of 9.7-11.1. It is widely used in biochemical analysis and in vitro diagnostic industries.
Desheng Bio has been engaged in the research and development and production of biological buffering agent projects for many years and has very rich experience. CAPS is one of the core products, and it is well received in the field of biochemical diagnostic reagents and the new coating supplies market. Desheng has established a company for decades. The company's products are sold globally. At present, it has been sold to more than 100 countries around the world. The products are of good quality and more favorable prices. If you are interested, you can call for consultation. Desheng Bio welcomes your calls.