Ethylenediaminetetraacetic Acid EDTA EDTA K2/EDTA K3 Uses And Preparation Methods

Uses and preparation methods of ethylenediaminetetraacetic acid (EDTA),EDTA K2/EDTA K3

Ethylenediaminetetraacetic acid, also known as EDTA, belongs to an organic compound. Its appearance is white crystalline powder, odorless and tasteless, with a melting point of 250°C. It is soluble in alkaline solutions such as sodium hydroxide, sodium carbonate and ammonia solution, slightly soluble in water, and insoluble in organic solutions such as ethanol. Ethylenediaminetetraacetic acid is mainly used as disodium salt, and its application fields are many and wide-ranging. Because ethylenediaminetetraacetic acid is a chelating agent that can combine with divalent metal ions such as Mg2+, Ca2+, Mn2+, and Fe2+. Most nucleases and some proteases require Mg2+ to function, so ethylenediaminetetraacetic acid is often used as an inhibitor of nucleases and proteases.

Ethylenediaminetetraacetic acid is also a kind of chelate, which can combine with calcium in the body to form chelated calcium. Therefore, ethylenediaminetetraacetic acid has a lubricating effect, an emulsifying effect and a dissolving effect on the dentin, which is beneficial to the enlargement of the root canal. With years of development, the current technology and level of ethylenediaminetetraacetic acid in root canal treatment have been significantly improved, and ethylenediaminetetraacetic acid has been used more clinically.

Ethylenediaminetetraacetic acid is an important complexing agent. It has a wide range of uses, and can be used as a bleaching and fixing solution for the processing of color photosensitive materials, dyeing aids, fiber processing aids, cosmetic additives, blood anticoagulants, detergents, stabilizers, synthetic rubber polymerization initiators, and ethylenediamine Tetraacetic acid is a representative substance of chelating agents. It can form stable water-soluble complexes with alkali metals, rare earth elements and transition metals. In addition, it can also be used to detoxify harmful radioactive metals from the human body quickly. It is also a water treatment agent. Ethylenediaminetetraacetic acid is also an important indicator, but it is used to titrate metal nickel, copper, etc., when it is used, it must be used with ammonia to act as an indicator.

In addition, the preparation method of ethylenediaminetetraacetic acid is as follows:
Ethylenediamine reacts with formaldehyde and sodium cyanide. Mix 60% ethylenediamine aqueous solution, 30% sodium cyanide aqueous solution and sodium hydroxide, keep at 20℃ and mix for 0.5h. Then the aqueous formaldehyde solution was added dropwise. After the reaction, water was distilled off under reduced pressure. Then repeat the above operation, adding excess formaldehyde for the last time to completely react the sodium cyanide. Adjust the pH to 1.2 with dilute acid. A white precipitate separated out, filtered, washed with water, and dried at 110°C. 

Hubei Xindesheng Material Co., Ltd. is a manufacturer of blood collection tube additives. The EDTA-k2/k3/na2 products developed and produced by our company are professional blood anticoagulant products. In addition, our company also produces heparin series and coagulant series , Siliconizing agent series, potassium oxalate and sodium fluoride and other products. Moreover, our company is a professional biochemical reagent manufacturer, and it also has the research and development and production of biological buffers, chemiluminescence reagents, chromogen substrates, enzyme preparations, carbomers and other products. If you are interested in understanding our products, you can enter our official website to contact customer service for more information. Hubei Xindesheng welcomes your visit.

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