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Latest company new about Desheng takes you to understand the four major characteristics of acridinium ester DMAE-NHS!
2021/03/05

Desheng takes you to understand the four major characteristics of acridinium ester DMAE-NHS!

Acridine ester DMAE-NHS is a luminescent chemical reagent with a yellow solid powder appearance. Because no catalyst is needed, the reaction conditions are mild, and the reproducibility is good, the application field is very wide. Acridinium Ester-DMAE-NHS is mainly used for: chemiluminescence and immunoassay, receptor analysis, nucleic acid and peptide detection, etc. It also plays an important role in the TSH screening test items and can also detect the thyroid. Understand its four main characteristics.   Luminescence properties of acridinium ester-DMAE-NHS   The luminescence of acridinium ester-DMAE-NHS is flash type, the luminous intensity reaches the maximum at 0.4s, the luminous intensity decreases rapidly in the first 2s, and the luminous intensity decreases slowly after that. The luminous half life is about 0.9s. Changing the concentration of acridinium ester-DMAE-NHS only affects the size of the luminous intensity, but does not affect the time and half-life of the maximum luminous intensity.   Product packaging   Thermal stability of acridinium ester-DMAE-NHS   The thermal stability of acridinium ester-DMAE-NHS decreases with increasing pH and temperature. At room temperature, DMAE-NHS is relatively stable in PB buffer with pH of 5.8, 7.0, and 8.0. After 16 days, the luminescence activity decreased by 1.6%, 3.6%, and 8.3%, respectively. At 37℃, the luminescence activity of DMAE-NHS in PB buffer with pH 5.8, 7.0 and 8.0 decreased by 8.9%, 22% and 42% respectively after 16 days.   Hydrolysis rate of acridinium ester-DMAE-NHS   The reason why the luminescence activity of DMAE-NHS in PB buffer decreases with time is due to hydrolysis, which is beneficial to hydrolysis in an alkaline environment. Increasing temperature is also beneficial to hydrolysis, that is, the hydrolysis rate of DMAE-NHS varies with the pH of the solution. Increase and speed up with temperature rise.   Advantages of Desheng Acridine Ester DMAE-NHS   Compared with traditional acridine esters, DMAE-NHS has higher luminous efficiency, better thermal stability, and stronger hydrophilicity. The chemiluminescence reagent has high photon yield and low background. It is compatible with proteins, antigens, and antibodies. After coupling, the luminous efficiency is almost unaffected, making it an excellent chemiluminescence immunoassay labeling reagent.   Desheng acridine ester DMAE-NHS is a golden yellow powder under normal conditions. The texture is very fine and bulky. The purity of the HPLC method is greater than 98%, no peculiar smell, high sensitivity, high luminous efficiency, and strong stability. .
Latest company new about Can TRIS (Trishydroxymethylaminomethane) be used as a pharmaceutical intermediate?
2021/03/04

Can TRIS (Trishydroxymethylaminomethane) be used as a pharmaceutical intermediate?

Pharmaceutical intermediates refer to chemical raw materials or chemical products used in the process of pharmaceutical synthesis. From the development history of China's pharmaceutical intermediates industry, after nearly 30 years of development, pharmaceutical intermediates have developed from a small branch of the chemical industry to a new industry with an output value of billions of yuan, and its market competition is becoming increasingly fierce. Now Desheng Xiaobian will introduce several common pharmaceutical intermediates for you.   Tris base(trimethylol aminomethane) Tris actually has another name, tromethamine, which is also related to its role in the field of medicine. In the field of medicine, Tris is also widely used in medicine. Tris is the intermediate of fosfomycin tromethamine. Fosfomycin tromethamine is a kind of broad-spectrum antibacterial drug which was launched in the late 1980s. Its bioavailability is 3 ~ 6 times of that of fosfomycin calcium, which is more suitable for the treatment of urinary tract infection and other diseases. Tris, as an organic amine, can form water-soluble double salt with insoluble substances with acidic groups. The most common eye drops containing Tris are ketorolac tromethamine eye drops.     Methyl 4,4 '- dimethoxyacetoacetate Methyl 4,4 '- dimethoxyacetoacetate is an important intermediate of nifedipine for the treatment of cardiovascular and cerebrovascular diseases. It is the leading drug for the treatment of cardiovascular and cerebrovascular diseases in the international market, but it has not been produced in China. Methyl 4,4 '- dimethoxyacetoacetate was synthesized from glyoxylic acid and trimethyl orthoformate in the presence of concentrated sulfuric acid. The latter reacted with methyl acetate and sodium methoxide to obtain methyl 4,4' - dimethoxyacetoacetate.   Pazopanib Pazopanib is a new oral angiogenesis inhibitor developed by GlaxoSmithKline company, which can interfere with the angiogenesis required for the survival and growth of refractory tumors. It targets vascular endothelial growth factor receptor (VEGFR) and works by inhibiting the angiogenesis of tumor blood supply. It is suitable for the treatment of advanced renal cell carcinoma (a type of renal carcinoma with cancer cells found in renal tubules), soft tissue sarcoma (STS), epithelial ovarian cancer and non-small cell lung cancer (NSCLC).   To sum up, Tris can be used as pharmaceutical intermediates. In addition to pharmaceutical applications, it can also be widely used in in vitro diagnosis, biopharmaceutical, cosmetics, paint and other industries. Desheng is a professional Tris reagent manufacturer, and its customers are the most in the application of buffers. Due to its high buffering efficiency and guaranteed quality, there are more than 50 stable cooperation customers at home and abroad .
Latest company new about Acridine ester can detect DNA damage caused by formaldehyde and acetaldehyde!
2021/03/04

Acridine ester can detect DNA damage caused by formaldehyde and acetaldehyde!

Various exogenous and endogenous factors, such as environmental pollutants, ionizing radiation, drug chemotherapy, and cell metabolism, can cause various forms of DNA damage. Among them, DNA double-strand breaks have the most serious damage to genome stability and can threaten the survival of cells. Establishing a simple, rapid and sensitive method for detecting DNA hybridization and genotoxicity effects is a very meaningful research topic. Here is a brief introduction to the method of DNA damage detection. What are the types of DNA damage detection DNA damage detection methods include gel electrophoresis, ultraviolet spectrophotometry, fluorescence and electrochemistry, and chemiluminescence analysis. Chemiluminescence analysis (CL) has been widely used in the fields of environment and life sciences due to its high sensitivity, wide linear range, convenient operation, fast analysis, and easy automation. Formaldehyde and acetaldehyde are both environmental pollutants. To a certain extent, it can cause DNA damage. Study the amount of acridinium esters embedded in DNA before and after the damage of formaldehyde and acetaldehyde, causing changes in the chemiluminescence intensity of acridinium esters, and study the damage behavior of formaldehyde and acetaldehyde on DNA. Establish a simple chemiluminescence analysis method to evaluate the degree of DNA damage caused by formaldehyde and acetaldehyde. Acridine esters method for detecting environmental damage to DNA 1. First, soak the glass luminescence cell used in a certain amount of concentrated nitric acid for several hours, acidify, and then rinse with water. Add 20 μL of 1mg/mL calf thymus DNA to the acidified luminescence cell, and place it for 1 hour to make The DNA is adsorbed on the bottom of the light-emitting pool, and then the unadsorbed calf thymus DNA is washed with secondary water to obtain the light-emitting pool with DNA adsorbed. 2. Add 50μL of 9.6×10-7g/mL acridinium ester to the luminescent cell, and the chimerization reaction is for 1h to embed the AE in the DNA double-stranded structure, and wash away the unchimeric AE with secondary water. Finally, in the luminescent cell Add luminescence initiation reagents in sequence to detect the chemiluminescence generated by AE chimerized in DNA. When detecting the damage of calf thymus DNA by formaldehyde and acetaldehyde, add damage reagent to the DNA after AE chimerization, and use it after a certain period of time. The second water washes away the AE released after the DNA is damaged, and the luminescence initiation reagent is added to detect the chemiluminescence intensity of the AE chimeric in the DNA. Studies have shown that acridinium ester can be used as a chemiluminescence indicator with a good structure of intercalating DNA double helix. This detection method is feasible for DNA break damage and chemiluminescence detection method. It has the advantages of simplicity and sensitivity. Damage studies provide a simple research method. Desheng acridine ester luminescent markers have the properties of good hydrolytic stability, thermal stability and high signal-to-noise ratio, and the labeling conditions are mild, the labeling rate is high, and the separation does not affect the separation after labeling. , So it is considered to be an ideal chemical marker.
Latest company new about Nsp-dmae-nhs acridine ester manufacturer
2021/03/03

Nsp-dmae-nhs acridine ester manufacturer

When it comes to acridine ester, many friends who want to buy it will have a headache, because it is too difficult to find a real manufacturer. Generally, they are dealers. Desheng biochemical is one of the few professional manufacturers of chemiluminescence reagents, especially acridine ester series. There are six different groups, different characteristics, and the characteristics of various groups are also different, which meet the needs of all kinds of testing.   Nsp-dmae-nhs belongs to acridine ester, acridine salt and acridine hydrazide. The characteristic of nsp-dmae-nhs is to increase the steric hindrance and enhance the hydrolysis resistance. Nsp-dmae-nhs is more suitable for some luminescent reagents that can not be changed to detect solvents.   After experimental comparison, nsp-dmae-nhs at room temperature, pH 7.0, luminous efficiency is also very slow to reduce, with NHS active ester, conventional coupling reaction. In the market, the sales of this model is also much higher than other models.     Although the luminous efficiency of acridine ester is much higher than other luminous reagents, many manufacturers still choose other luminous reagents. The reason is that the price of acridine ester is much higher than other reagents. Of course, if the buyer finds a dealer, then the price is more likely to double.   Cas194357-64-7, acridine ester nsp-dmae-nhs purity > 98%, yellow powder, Desheng biochemical was established in 2005, focusing on blood test reagent manufacturers, products now include many fields, but the more advantages have to mention acridine ester series, from research and development to detection to production, Desheng a professional research and development team to operate, laboratory production, not only batch difference Small size, low background and high luminous efficiency.   Acridine ester series has been used in major domestic enterprises, and exported to foreign countries to form stable sales, establish cooperative relations, good product quality, price concessions, hope to let more friends in need see contact us.
Latest company new about Is the chemiluminescence of acridinium esters the same as that of fluorescence immunity?
2021/03/03

Is the chemiluminescence of acridinium esters the same as that of fluorescence immunity?

Acridine ester chemiluminescence reagent is a commonly used detection reagent in the field of in vitro diagnostics. Its chemiluminescence is not like the substrate of HRP or ALP and can directly chemiluminescence. So what is the difference between the chemiluminescence of acridinium ester and the fluorescence in fluorescence immunity? What's the difference? Chemiluminescence is a molecular luminescence phenomenon in which the product returns from the excited state to the ground state when a substance produces a chemical reaction. In fact, there are three types of molecular luminescence: chemiluminescence, fluorescence, and phosphorescence. Their luminescence principles are different: Chemiluminescence in nature 1. Principles of Chemiluminescence For example, the chemical reaction between acridine ester and hydrogen peroxide produces another acridinium ester derivative. The energy released by the reaction is absorbed by the molecules of this product and transitions to an excited state, and the excited molecule returns to the ground state. Light radiation is generated during the process. The product here is a luminous body, and the luminescent product directly participates in the reaction during this process, so it is called direct chemiluminescence. Luminol's luminescence principle is similar, but requires HRP or POD catalysis, so it is called enzymatic chemiluminescence. 2. The principle of fluorescence When light irradiates certain atoms, the energy of the light makes some electrons around the nucleus transition from the original orbit to a higher energy orbit, that is, transition from the ground state to the first excited singlet state or the second excited singlet state. The first excited singlet state or the second excited singlet state is unstable, so it will return to the ground state. When the electron returns from the first excited singlet state to the ground state, energy will be released in the form of light, so fluorescence is generated. 3. The principle of phosphorescence When a certain room temperature substance is irradiated with incident light of a certain wavelength (usually ultraviolet or X-ray), it absorbs the light energy and enters an excited state (usually with a spin multiplicity different from the ground state), and then slowly de-excites and emits a ratio. Outgoing light with a long wavelength of incident light. Seeing this, many people may still not be able to distinguish, but it doesn't matter. For example, the luminescence of fireflies belongs to bioluminescence or chemiluminescence, phosphorous fire or "ghost fire" is also chemiluminescence, and fluorescent sticks are also chemiluminescence; ultraviolet rays illuminate RMB anti-counterfeiting signs to emit fluorescence; luminous pens and luminous watches belong to phosphorescence. In daily life, people usually call all kinds of faint light fluorescence in a broad sense. In the field of analysis and detection, chemiluminescence immunoassay and fluorescence immunoassay are two different detection methods, which need to be distinguished. Luminol and acridine esters of Desheng belong to chemiluminescence reagents, and the reagents for fluorescence immunity are reagents of different systems.
Latest company new about Factory direct selling carbomer 130 yuan / kg
2021/03/02

Factory direct selling carbomer 130 yuan / kg

Desheng Material Technology Co., Ltd. carbomer spot sufficient, price reduction, volume promotion, manufacturers direct sales, spot direct supply, to avoid middleman price difference, buy carbomer discount in the end.   This article is just a brief introduction of carbomer. If you want to consult carbomer or want to know more details and specific price information, please contact us by telephone or go to Desheng website for detailed consultation.   The event is targeted at products, Carbomer 940 and carbomer 980, Carbomer is routinely used in hand free gel, daily chemicals, medicine and so on. In the use of more attention to viscosity and transparency and other issues, and Desheng material production of carbomer with pure white powder, high transparency, viscosity can be adjusted according to the direction of use and other characteristics.     Desheng was founded in 2005, specializing in polyacrylic acid material products. So far, it has developed three generations of serum separation gel with different uses and carbomer products for non use. Professional R & D team is one of the important conditions for Desheng to have confidence in the market, and market feedback is the best touchstone.   The big difference between Desheng carbomer and ordinary carbomer on the market is that the powder of Desheng carbomer is obviously white, and the powder is more fluffy and delicate. In the configuration of solvent, the transparency is also much higher than that of similar products. As Desheng is a direct manufacturer, individual indicators can also be customized.   No matter it is used by direct customers or purchased by traders, it is a very good choice. It can be purchased in small quantities, or it can sign annual contracts to enjoy ultra-low price discounts. Product quality is guaranteed at the same time, unlimited price concessions, after-sales service to enjoy product quality problems can apply for direct return, or refund, real manufacturers, reliable products, choice is very important!
Latest company new about Is the abnormal PCR amplification curve caused by the virus transport media ?
2021/03/02

Is the abnormal PCR amplification curve caused by the virus transport media ?

In the nucleic acid detection of the new coronavirus, the very key technology is the real-time fluorescent quantitative PCR experiment of nucleic acid, which is the core technology of the new coronavirus detection. So what effect does the virus transport media used for virus sampling joints have on the PCR amplification of nucleic acids? This article makes a brief discussion. Does the virus transport media affect nucleic acid PCR amplification? Judging the result from the PCR amplification curve: The fluorescent quantitative PCR instrument in the new crown detection has become a routine equipment for molecular biology research. The rapid development of this detection method and the urgency of the detection task have also put forward higher requirements for the detection personnel, requiring them to be proficient in judging the results of the data. For the judgment of the result of fluorescence quantitative PCR, the most intuitive judgment is to see whether the amplification curve is normal. In normal experiments, you will encounter problems with abnormal amplification curves, such as discounted amplification curves, poor repeatability between multiple wells, and uplifted amplification curves of negative samples.   Reasons for abnormal PCR amplification curve: 1. Confirm whether the software settings are correct. Check the kit instructions to check whether the time, temperature, cycle number, fluorescence collection, etc. are set correctly, and whether the selected reagent contains ROX as a reference fluorescent dye. Some results show that the amplification curve of the multi-component graph is not uplifted, which is obviously a negative sample, but the amplification graph curve is uplifted, so that it crosses the threshold line, and instead has a CT value. This is because the software makes a mistake in the automatic deduction of the baseline. The method of manually adjusting the baseline can be normal by redefining the baseline.   2. Make sure that the consumables and instrument accessories are used correctly. Consumables are more important for real-time PCR. Many abnormal amplification curves are caused by improper use of consumables.   3. To determine whether the reagents used are normal, first determine whether the reagents are effective, including checking whether the reagents are within the validity period, whether they are repeatedly frozen and thawed many times, and whether the transportation conditions are normal. If all of the above are normal, then you have to consider whether there is any negligence in the operation details.   From the above points, it can be seen that the virus transport media will not directly affect the amplification curve, it will only affect the virus samples, but this can be done through a control experiment with positive samples to determine whether the virus preservation solution has an impact on the virus samples. . There are two types of Desheng virus transport media, both the inactivated type and the activated type are suitable for nucleic acid PCR experiments.
Latest company new about The New Trinder’s reagent DAOS detection road and
2021/03/02

The New Trinder’s reagent DAOS detection road and "stumbling block"

Nowadays, as long as people have a headache and brain fever, they first go to the hospital for testing to find out where the problem lies, and then prescribe the right medicine. In fact, many people only know the test items, but they don't know much about the test materials. The DAOS reagent in the new Trinder’s reagent is a very important test material, which has the advantages of good water solubility, high sensitivity, and strong stability. Let's take a look at the past of DAOS on the road of detection.     DAOS can be used for cholesterol testing   When measuring total cholesterol, the cholesterol ester is firstly hydrolyzed into cholesterol and fatty acid by cholesterol esterase CHE, and then it is catalyzed and oxidized to 4-cholestenone and hydrogen peroxide by cholesterol oxidase, and then it is through DAOS and 4-AAP Coupling with hydrogen peroxide to produce a color reaction under the catalysis of POD, the concentration of total cholesterol can be determined by measuring the absorbance.   DAOS can be used for triglyceride detection   When detecting triglycerides, triglycerides are hydrolyzed into glycerol and fatty acids in the presence of lipoprotein esterase (LPL); glycerol and ATP are catalyzed by glycerol kinase (GK) to generate glycerol-3-phosphate and ADP; glycerol-3- Phosphoric acid and oxygen are catalyzed by glycerol-3-phosphate oxidase (GPO) to generate dihydroxyacetone phosphate and hydrogen peroxide, and then use the color substrate to couple 4-AAP and hydrogen peroxide to produce color as in the above steps. In response, the TG concentration was measured.   DAOS can be used for high-density lipoprotein detection   When detecting high-density lipoprotein, a dual-reagent reaction is used. Reagent one contains polyanion and surfactant, which selectively binds to VLDL and LDL, and inhibits COD and CEH in reagent two on VLDH-CH and LDH-CH. , Thereby selectively acting on HDL-CH, through the action of CEH-COD-POD, and then measuring the absorbance to determine the concentration of HDL, and finally the LDL concentration can be obtained by calculation.   Cautions when using DAOS:   1. Divided packaging: When taking a small amount of mg DAOS, the product needs to be divided into the quantity needed each time to reduce the number of bottle openings and prevent the product from absorbing moisture.   2. Use: When using the product, you need to take out the product from the freezer half an hour in advance and place it at room temperature.   For the remaining, store the remaining DAOS in a sealed and light-proof container to avoid quality problems such as changes in color or properties of the product.   3. Preservation: Place DAOS in a 0-5 degree freezer, and record the time and batch number.   4. Transportation: Put ice cubes in the foam box for the packed products and wrap the products with foam glue. Take care to prevent the water from the ice cubes from getting the product wet (we put two more if the temperature is high, and the weather can be changed in winter. Temperature to decide)
Latest company new about What are the advantages of acridine esters in luminescent reagents
2021/03/01

What are the advantages of acridine esters in luminescent reagents

Acridine ester is a kind of important chemiluminescence reagents, which has high quantum yield and high chemiluminescence efficiency. As a chemiluminescence marker, the luminescence system is simple, the natural background is low, the interference is less, and the signal-to-noise ratio is high. When used as a chemiluminescence marker, it has the advantages of easy coupling, simple labeling, good stability, and less influence on its luminescence performance In the presence of sodium hydroxide and hydrogen peroxide. In addition, acridine ester chemiluminescence reagents have good stability and are easy to store.   According to the different substituents, acridine substitutes commonly used as chemiluminescence markers can be divided into two categories: acridine ester and acridine sulfonamide. They all share the same acridine ring. Their luminescence mechanism is the same: in the alkaline H2O2 solution, when the molecule is attacked by hydrogen peroxide ion, the unstable dioxane is generated, which is decomposed into CO2 and n-methylacridone in the electron excited state. When it returns to the ground state, it emits photons with the maximum emission wavelength of 430nm.     The characteristics of these compounds are as follows:    ① In the luminescent reaction, the non luminescent substituents attached to the acridine ring are separated from the acridine ring before the formation of the electron excited intermediate, that is, the non luminescent part is separated from the luminescent part, so the luminescent efficiency is not affected by the substituent structure.   ② The chemiluminescence of acridine esters or acridine sulfonamides can be obtained in dilute alkaline solution with H2O2 without catalyst. Therefore, it has many advantages in chemiluminescence detection.   The main advantages are as follows:   1. Low background illumination and high signal-to-noise ratio   2. The interference factors of luminescent reaction are few   3. Fast and concentrated light release, high luminous efficiency and high luminous intensity   4. It is easy to bind with protein, and the photon yield does not decrease after binding, thus increasing the sensitivity   5. The solid phase separation agent is very fine magnetic powder, which not only increases the coating area and accelerates the reaction, but also cleans at the same time.
Latest company new about Carbomer reserve price promotion
2021/02/28

Carbomer reserve price promotion

The only difference between Desheng cabomer and imported brands is the price. The spot price of Desheng cabomer is as low as 130 yuan / kg, and the quantity is limited, so we miss the next batch. For cosmetic raw materials, pharmaceutical gel, hand gel free, etc., please contact the German Sheng website or the phone left by the network.   Desheng has been committed to the research of polyacrylic acid. Besides the serum separation gel series, Carbomer series is also a long-term series. With 15 years of R & D and production experience, Desheng carbomer products are more reliable!   Carbomer products were first produced abroad, and now a foreign brand still controls more than 80% of the market. The reason for this situation is nothing more than the gap in technical ability. After continuous research and development efforts in recent years, Desheng has finally been able to achieve the situation of "no one, no one, no one, no one, no one, no one, no one, no one, no one, no one, no one, no one, no one, no one, no one, no one, no one, no one, no one, no one, no one, no one, no one, no one, no one, no one Price is also to expand the reputation and win by quantity. I hope more customers can know Desheng.     Desheng put forward that the preferential price of carbomer products is in the end, the product quality is guaranteed to be the best, free samples, perfect after-sales service, if you have problems, you can contact a professional one-to-one sales manager for full-time service, and for product problems, the whole process of technical participation, you know, we communicate with each other, you don't understand, we understand, we teach!   As a widely used carbomer product, Desheng is very welcome to retail and wholesale, small quantity and large quantity. We also hope that all partners can take time to visit our factory, so as to further win-win cooperation. Desheng cabomer's regular guarantee is 10kg / bag. According to the customer's requirements, it can also customize the product index and separate the packaging according to the special requirements.   According to the change of market price, the price will increase or decrease according to the demand of customers. Please call our friends to inquire. It's also very good to add a waiting material supplier!
Latest company new about What are the types of Virus Transport Medias?
2021/02/27

What are the types of Virus Transport Medias?

Since the outbreak of the new coronavirus, the Virus Transport Media has played an important role. First, the nasal and pharyngeal swabs were used to sample, and the samples were put into the sampling tube added with the Virus Transport Media for sample protection, which improved the accuracy of nucleic acid detection. Virus Transport Media is a solution medium used for virus sampling, transportation, storage and detection. If it is added into the virus sampling tube, what kinds of Virus Transport Media are added?   There are two kinds of Virus Transport Medias, inactivated and non inactivated. There are many kinds of Virus Transport Medias on the market. The following is a brief introduction of several principles for the selection of Virus Transport Medias. Non inactivated preservation solution: Based on Hank's, the non inactivated virus does not contain lysate, and is supplemented with nutrients needed by virus, such as BSA (bovine serum albumin) amino acids, vitamins, etc. it can maintain the activity of virus in a wide temperature range and keep the original sample to the greatest extent. It can be used for virus nucleic acid extraction and detection, virus culture and isolation.   Characteristics of non inactivated preservation solution: 1. The virus can remain active and can be used for detection or virus isolation; 2. There was no inhibition on subsequent nucleic acid amplification, which could be matched with direct amplification reagent; 3. After the swab is added, it needs to be refrigerated to detect the main components as soon as possible.   Inactivated preservation solution: Inactivation preservation solution can fully mix the collected samples with virus lysate and virus nucleic acid preservation solution to inactivate the virus in the samples, and effectively ensure the integrity of virus nucleic acid in the samples. The collected samples can be transported under normal temperature and preserved for a long time. The preserved virus RNA samples can be widely used in gene detection, enzyme-linked immunosorbent assay (ELISA), PCR detection and so on. The inactivation preservation solution can be divided into guanidine containing solution and non guanidine containing solution.   1. Guanidine salt (1) The virus can be split and inactivated instantaneously to reduce the risk of sampling; (2) The viral nucleic acid could be stored at room temperature for 2 weeks; (3) It can match most nucleic acid extraction reagents.   2. Non guaiac salt (1) The virus can be inactivated instantaneously to reduce the risk of sampling, and the virus may recover its infectivity after dilution; (2) The viral nucleic acid could be stored at room temperature for 2 weeks; (3) It can match most nucleic acid extraction reagents.   3. Direct expansion preservation solution (1) The virus can be inactivated instantaneously to reduce the risk of sampling, and the virus may recover its infectivity after dilution; (2) The viral nucleic acid can be stored in cold storage for 24-48 hours; (3) It can be directly added into nucleic acid amplification system as template; (4) Most of the nucleic acid extraction reagents and releasing agents were matched.   I believe that after reading the above explanation, we will have more basis for choosing the correct and applicable preservation solution. Desheng is a manufacturer of Virus Transport Media, which can provide inactivated and non inactivated preservation solutions. We can accept customized samples from customers, and also provide disposable virus sampling tube and nasopharyngeal swab, etc. to provide customers with one-stop service. If you need, you can click the official website for consultation or contact directly Our professional sales staff.
Latest company new about Hot sale of Desheng nsp-dmae-nhs acridine ester products
2021/02/26

Hot sale of Desheng nsp-dmae-nhs acridine ester products

The recent hot sale of acridine ester nsp-dmae-nhs is something I didn't think of. Why I didn't think of it is not because this product is not good, but because Desheng has developed and produced acridine ester products with six different groups, but only nsp-dmae-nhs has top sales.   As of yesterday, the warehouse has been cleared, which is also the product that has been cleared quickly since 2021. It has been replenished three times, but each time it can be sold out in a short time.   In recent years, the development of chemiluminescence is not only in the research and development of instruments, innovation, but also in the use of reagents. More advanced enterprises adopt the world's more mainstream luminescence reagent acridine ester, which is not only simple in labeling, high in luminous efficiency, but also its stability is incomparable with other luminescence reagents.   Product packaging   Desheng also produces luminol series products, but there are some limitations compared with acridine ester. The luminous efficiency of acridine ester is 4-5 times that of luminol, and the labeling method of luminol is more complex than acridine ester. With the continuous progress of human beings, complex things think of simpler evolution and development.   Desheng nsp-dmae-nhs is a golden powder in the normal state. Its texture is very fine and bulky. Its purity is more than 98% by HPLC. It has no peculiar smell. The market feedback is good. Nsp-dmae-nhs is very stable at pH 7.0, and its water solubility test is added in this model, which can be carried out in water in the detection of antigen nucleic acid.   Compared with other acridine salts, acridine hydrazide and nsp-dmae-nhs have moderate price and better luminous efficiency. Desheng has a large stock and more favorable price. Desheng has a professional R & D team, such luminescent reagent products are developed and produced by our company, and the quality is guaranteed. The products can be repacked according to the needs of customers. Of course, due to the high value of acridine ester, small repacking will calculate the loss, and the price will be higher.
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