Application of serum separation gel in multiple types of blood collection tubes

Serum separation gel is a key material for achieving liquid-liquid phase separation in blood collection tubes. It stabilizes between serum or plasma and blood cells after centrifugation with precisely controlled specific gravity, forming a dense isolation barrier. The use of separation gel alone can already meet conventional detection needs, while when combined with different additives, separation gel has evolved into specialized tube types for special detection scenarios.

SST coagulation tube: accelerates serum separation

SST tube is one of the most common application scenarios for separating adhesives. Simultaneously add coagulant and serum separation gel into the tube. After blood collection, coagulants accelerate the coagulation process and significantly reduce sample waiting time. After the blood has completely coagulated, centrifuge and transfer the separation gel between the serum and the blood clot. Clear serum can be directly used for biochemical, immunological, and other testing projects without the need for lid opening transfer, which not only improves efficiency but also reduces the risk of aerosol contamination.

PST plasma separation tube: safeguarding the stability of plasma components

Unlike SST tubes, PST tubes use anticoagulants such as lithium heparin or sodium heparin combined with serum separation gel. Anticoagulants prevent blood clotting, and after centrifugation, plasma is obtained instead of serum. Separation gel also forms a barrier between plasma and blood cells, ensuring the stability of plasma components during transportation and storage. For scenarios that require rapid detection of electrolytes, enzymes, or drug concentrations in plasma, PST tubes provide a reliable treatment solution.

PRP Rich Small Plate Plasma Tube: Accurate Extraction of Platelets

The design of PRP tube is more refined. Add EDTA anticoagulant and serum separation gel inside the tube. EDTA achieves anticoagulation by chelating calcium ions, while maintaining the original morphology of blood cells effectively. After centrifugation, the separation gel clearly separates the upper platelet rich plasma from the lower red and white blood cells. This tube type can obtain a higher concentration of platelet suspension for platelet function analysis or preparation of platelet rich plasma products.

CPT monocyte isolation tube: isolate specific cell populations

CPT tube is a type of blood collection tube with stronger functionality. It also uses a combination of anticoagulant and separation gel, but its design goal is to separate lymphocytes and monocytes in whole blood. Under the precise control of centrifugal force, the mononuclear cell layer aggregates in a specific area above the separation gel, facilitating subsequent extraction. This type of blood collection tube is widely used in scenarios that require high cell purity, such as immunological monitoring, cell therapy research, and viral load detection.

Nucleic acid testing tube: ensuring the quality of nucleic acid extraction

Nucleic acid testing requires extremely high sample quality, and any contents released by the rupture of blood cells may interfere with amplification testing. In nucleic acid detection tubes, separation gel combined with a specific anticoagulant system can quickly and completely isolate plasma from cellular components after centrifugation, avoiding the sustained impact of cellular metabolism or degradation on nucleic acids. This design ensures the long-term stability of plasma components, supports sample transportation, storage, and subsequent amplification testing.

The functional boundary of the separation gel continues to expand from serum separation in SST tubes to monocyte enrichment in CPT tubes. By flexibly combining with coagulants and anticoagulants, the same type of separation gel material can serve various application scenarios from conventional biochemistry to cell therapy. Understanding the design logic of different tube types can help blood collection tube manufacturers and inspection departments make precise selections based on their own needs.

Hubei Xindesheng Material Technology Co., Ltd. focuses on the research and production of blood collection tube additives such as serum separation gel. We have advanced production equipment and a professional R&D team, strictly controlling product quality to ensure that each batch of serum separation gel can meet the strict requirements of different medical scenarios. Choosing Hubei Xindesheng means choosing professionalism, stability, and reliability. Come and consult us now!