China Wuhan Desheng Biochemical Technology Co., Ltd Company News

The rapid development of the medical industry is leading the innovation of global medical technology, and in this trend, Desheng Biochemical will appear at the MEDICA exhibition, which will be an international medical event and a showcase platform that industry insiders cannot miss.   1、 Dusseldorf MEDICA: The World Stage of Medical Technology   MEDICA is one of the largest medical B2B trade exhibitions in the world, attracting medical professionals from around the world every year. With over 4500 exhibitors and over 81000 visitors from 66 countries worldwide, it provides a unique platform for innovation and development in the healthcare industry.   Here, exhibitors and visitors can share their latest products, technologies, and research achievements, explore industry trends, establish connections, and jointly promote the development of medical technology.   2、 Desheng Biochemistry: a leader in the medical field   As a national high-tech enterprise founded in 2005, Desheng Biochemical has demonstrated outstanding development performance in the medical field. The company's main product line is blood collection additives, biological buffers, chemiluminescent reagents, and chromogenic substrates. The core products are as follows:   (1) Additives for blood collection: serum separation gel, heparin lithium, heparin sodium, EDTA dipotassium/tripotassium/disodium, coagulant, high-efficiency coagulant powder, etc;   (2) Biological buffer: Tris, Tris HCL, Bicine, Caps, Mops, Taps, Epps, etc;   (3) Chemiluminescence reagents: Luminol, Isoluminol, Acridine ester;   (4) New Trinder's reagents: TOOS, TOPS, ADOS, ADPS, ALPS, DAOS, MAOS, etc;   Provide one-stop services to customers through research and development, production, and sales. Desheng Biochemical has established an excellent reputation in the industry with its continuous innovation spirit and high-quality products.   3、 Desheng Biochemistry: Honor added along the way   Desheng Biochemical has won multiple honors along the way due to its continuous pursuit of technological progress. The company has won honors such as the Gedian Development Zone Science and Technology Progress Award Enterprise, Hubei Province Science and Technology Small and Medium sized Enterprise, and National High tech Enterprise.   At the same time, the Hubei Provincial Department of Science and Technology has agreed to register with the Hubei University Enterprise School Joint Innovation and Research Center, proving the company's outstanding contribution in research and development. Among them, in 2022, the research and development project of PRP autologous serum treatment separation gel was listed as a key research and development plan of the Provincial Department of Science and Technology. In 2023, it was awarded the title of the fifth batch of specialized, refined, and new small and medium-sized enterprises in Hubei Province, which is recognition of the company's breakthrough achievements in the field of biopharmaceuticals.   4、 Innovation driven: 12 patents firmly supported   Innovation is the key to the success of Desheng Biochemical, and the company currently holds 12 patents, including invention patents and utility model patents. These patents cover multiple fields, such as serum separation gel, luminol, aniline derivatives, carbopol, heparin sodium, etc. The holding of these patents has consolidated the company's leading position in the field of medical technology and provided a solid foundation for its future development.   5、 Showcasing the strength and style of "Desheng" to the world   At the MEDICA exhibition in Dusseldorf, Desheng Biochemical will showcase its latest products and technologies to the world. We will provide exhibitors with an opportunity to understand the forefront of medical technology, establish connections with industry experts and peers, and share experiences and insights.   6、 Invite you to meet at MEDICA 2023   For professionals and enthusiasts in the medical technology industry, attending the MEDICA exhibition in Dusseldorf will be a must-have opportunity. This is an ideal platform for understanding global medical technology development trends, interacting with experts in the field, and discovering new products and technologies. We sincerely invite you to visit the Desheng Biochemical booth, learn about our latest products, and jointly explore the future of medical technology.   The MEDICA 2023 exhibition in Dusseldorf is an important event in the field of medical technology, providing a broad stage for global medical technology innovation. Desheng Biochemistry actively participates, showcases its latest achievements, and shares its innovative ideas with professionals from around the world. We look forward to meeting you at the exhibition and exploring the infinite possibilities of medical technology together!   Address: Dusseldorf International Exhibition Center, Germany Booth number: 5G06 Time: November 13th to November 16th    

Heparin lithium, as an anticoagulant, plays an important role in clinical biochemical tests. Its main function is to prevent coagulation during the collection of blood samples, ensuring their stability and reliability. The principle of action is achieved by blocking the activity of thrombin, an enzyme that promotes blood clotting. Heparin lithium inhibits thrombin activity by binding to antithrombin III, thereby reducing blood clotting. What is its clinical function? Let's take a look together.   The biggest function of heparin lithium is in the collection of blood samples and anticoagulation during clinical biochemical examinations, especially for testing items that require the determination of ion content in the blood. Compared with other anticoagulants, heparin lithium has less interference in ion determination, enabling accurate and reliable results to be obtained during blood sample collection and ion content determination. Moreover, heparin lithium has an advantage that it can be used at room temperature and added to the blood collection vessel as a solution without special conditions. In addition, its anticoagulant performance ensures that the blood sample is not damaged and subsequent testing is smoother.   However, it should be noted that although heparin lithium is an effective anticoagulant, it is not a drug and cannot be used as an injection, nor should it be directly injected into human or animal bodies. The use of heparin lithium additive is limited to the process of collecting blood samples in the laboratory, with the aim of maintaining the original state of the blood samples and ensuring the accuracy of various biochemical tests.   In addition, in order to ensure the ideal anticoagulation effect of blood samples, test tubes containing heparin lithium should be immediately inverted after blood collection, especially when the ambient temperature is above 25 degrees Celsius, which is not well mixed and easily leads to a semi coagulation state and is not suitable for biochemical testing. And unlike other additives, heparin lithium must be tested within 6 hours and should not be left unused for too long. For sensitive indicators such as AST, ALT, TBIL, DBIL, GGT, etc., it should be ensured that most of the plasma indicators are repeatable within 6 hours.   Unlike heparin drugs, heparin lithium additives cannot be used for treatment or directly injected into human or animal bodies. If you need to use it, you should indicate the demand in advance.As a professional manufacturer of blood vessel additives, Desheng can provide analytical grade heparin lithium raw materials for blood collection manufacturers to use, and does not participate in human treatment. Before purchasing, please explain the purpose in advance to facilitate accurate customer service quotations. Interested parties are welcome to click on the website to inquire about details!

In laboratory and clinical medicine, anticoagulants are a common reagent that can be used to prevent blood clotting and ensure the stability of blood and biological samples, which is crucial for various tests and biochemical analysis. The two common anticoagulants among them are heparin lithium and EDTA (ethylene diamine tetraacetic acid). Although they are both added to test tubes as in vitro anticoagulants, their principles of action and applicable items differ greatly. Below, we will delve into the properties, application fields, and importance of these two anticoagulants in laboratory work.   Heparin lithium   Heparin lithium is a sulfur-containing polysaccharide with negative charges. Its main mechanism is to activate antithrombin III, prevent the activation of thrombin, and slow down the coagulation process. It is used in blood collection to prevent blood from clotting inside the tube, which maintains the fluidity of the blood sample for various clinical tests, such as hemodialysis and liver and kidney function testing. However, it should be noted that although heparin lithium performs well in anticoagulation, it can also interfere with certain experiments, such as thrombin time (PT), activated partial coagulation time (APTT), and international standardized ratio (INR) in coagulation tests. Therefore, when conducting such tests, it may be necessary to consider using other anticoagulants.   EDTA (ethylene diamine tetraacetic acid)   EDTA is a strong chelating agent that can form stable complexes with calcium and other multivalent metal ions. This characteristic makes it a superior anticoagulant and can exist in the form of EDTA dipotassium or tripotassium in clinical practice. In blood samples, EDTA is usually combined with calcium ions in the blood to prevent blood clotting, and is usually suitable for whole blood cell counting or blood biochemical analysis.   Precautions for the use of heparin lithium and EDTA   1. To ensure sufficient anticoagulation of blood, both heparin lithium tube and EDTA tube should be inverted and mixed 5-8 times immediately after blood collection, and it is important not to shake excessively to cause blood cell rupture.   2. Both heparin and EDTA tubes are non irreversible anticoagulants, and the experiment should be completed within a short period of time. Typically, heparin tubes are completed within 6 hours, while EDTA tubes are completed within 24 hours. Remember not to leave them for too long, as it may lead to abnormal results.   3. Note that there are differences in the dosage of the two types of tubes. According to industry standards, the dosage range for heparin lithium tubes is 9.4IU-28IU per milliliter of blood sample, while the standard dosage for EDTA potassium is 1.5-2.2mg per milliliter of blood.   Both heparin lithium and EDTA are important anticoagulants in clinical practice. When choosing anticoagulants, it is necessary to weigh them based on specific applications, experimental types, and possible interference factors. Correct selection and use are beneficial to ensure that experimental results do not deviate. As a manufacturer of heparin lithium, Desheng provides raw material powder of analytical purity level, without impurity interference, and is easy to preserve and prepare. It can be added in batches to blood collection vessels to improve efficiency. If you have any interest, please feel free to click on the website and contact us anytime to purchase!

Lithium heparin is a form of heparin, which appears as a white powder and is stable at room temperature. It has good water solubility and can be easily prepared into blood vessels. Due to its ideal anticoagulant effect, it is often applied in the medical field, suitable for detecting indicators such as blood sugar and liver and kidney function. Medical staff provide timely assistance to patients by analyzing sample data. So what exactly does it have on the blood? Let's take a look together.   Anticoagulant mechanism   The main function of heparin lithium is to prevent blood clotting by inhibiting the activity of thrombin. Thrombin is an enzyme that plays a crucial role in the blood coagulation process. Heparin lithium enhances the inhibitory effect of antithrombin III on thrombin by binding to it, thereby reducing its activity and slowing down the coagulation process, making blood less prone to clotting, thereby improving the efficiency of blood sample processing.   Application of heparin lithium in blood collection   Heparin lithium plays an important role in the preparation of blood vessels, as most biochemical tests require the blood to be in an uncoagulated state. In this case, it can serve as an anticoagulant to assist. It has the following characteristics in blood collection:   (1) Prevention of coagulation: Its main function is to inhibit thrombin, thereby avoiding blood coagulation during the blood collection process, ensuring that the collected whole blood sample remains in its original state before testing.   (2) High content: Usually, heparin lithium is in its original factory state as powder, and the raw materials prepared into the blood collection vessel are generally of high analytical purity, ensuring that it does not introduce any impurities or interfering factors and does not affect the accuracy of the test results.   (3) Stability: Heparin lithium is a stable anticoagulant that does not decompose or lose anticoagulant properties when added to test tubes at room temperature, which is beneficial for storing test tubes.   Heparin lithium, as an important anticoagulant, is widely used in the medical field. It prevents blood clotting by inhibiting the activity of thrombin, ensuring that collected blood samples remain in their original state for various tests. The premise for these effects is the quality of heparin lithium, and the choice of its source manufacturer is particularly important.   Here, we recommend that you choose Hubei Xindesheng, which can provide a full range of blood collection additives, all of which are analytical grade. It is a cooperative partner of most domestic blood collection manufacturers, and due to independent production and research and development, it is sold in stock, without shortage or shortage, with favorable prices. If there are any problems, after-sales service will solve them as soon as possible to ensure that customers can use them with confidence. If you have any interest, please feel free to contact us for purchase!

A dark green lithium heparin tube is commonly used for collecting and preserving blood samples, as it contains lithium heparin as a blood anticoagulant used to inactivate certain coagulation factors in the blood. In general, in medical practice, heparin lithium tubes play an important role in specific tests and tests, which are used to check blood ammonia levels and rheological parameters of the blood.   Applicability of heparin lithium tube:   1、 Check blood ammonia levels   Blood ammonia level refers to the concentration of ammonia nitrogen in the blood, usually expressed in mmol/L (millimoles/liter). Ammonia nitrogen is a form of ammonia, a compound of ammonia oxides, produced by the metabolism of amino acids in the liver. The liver is the only organ capable of relieving ammonia toxicity, so blood ammonia levels are crucial for evaluating liver function. Abnormal blood ammonia levels may indicate severe liver damage, such as liver diseases such as hepatitis and cirrhosis, or upper gastrointestinal bleeding, where blood breakdown increases ammonia nitrogen levels. By measuring blood ammonia levels, doctors can evaluate liver function and the patient's metabolic status.   2、 Hemorheological testing   Hemorheological testing is a testing method used to evaluate blood flow and viscosity. It mainly includes two parameters: whole blood viscosity and plasma viscosity. The former refers to the viscosity of the entire blood sample, and abnormal whole blood viscosity can be seen in various diseases, such as cardiovascular and cerebrovascular diseases, hypertension, coronary heart disease, as well as malignant tumors, anemia, etc. The latter refers to the viscosity of the plasma. Abnormal plasma viscosity can be seen in multiple myeloma, diabetes, etc. Hemorheological testing helps to understand the characteristics of blood, identify factors that may cause abnormalities, such as viscous blood that may increase the risk of cardiovascular and cerebrovascular diseases, and help doctors develop more accurate treatment plans.   These testing items require unconsolidated and stable blood samples, and the blood has been processed using heparin lithium tubes, which have no interference with blood components and are conducive to the smooth and effective completion of the above experiments, thus obtaining reliable results and timely treatment and prevention of related diseases for patients.   As a manufacturer of blood vessel additives, Desheng has a wide range of reagent product types and can provide customers with diversified choices. At the same time, due to its direct sales by the manufacturer, there is no secondary intermediary to make a difference in price, with favorable prices and stable supply. Welcome customers to conduct on-site inspections and feel free to click on the website to contact us if you have any relevant intentions!

Heparin lithium, as an anticoagulant, has a wide range of applications. Due to its natural anticoagulant properties, it plays an important role in blood sample collection and anticoagulation processes in clinical biochemical and emergency biochemical examinations. Since it is used as an anticoagulant reagent, it must also be very useful in the medical field. Let's take a specific look together.   1、 Clinical Biochemical Examination   Clinical biochemical tests include common blood tests, such as detecting ion content, liver function, kidney function, and blood lipid levels in the blood. The function of heparin lithium as an anticoagulant is to prevent premature coagulation of blood after collection, thereby ensuring the stability of blood samples. In these tests, accurate results are a prerequisite for disease diagnosis and treatment.   2、 Hemorheology project   Heparin lithium is not only used for general biochemical tests, but also widely used in hemorheology projects. Hemorheology mainly studies the flow properties of blood in blood vessels, which involves key indicators such as blood viscosity and cohesion. The addition of heparin lithium in these items can effectively prevent blood clotting and ensure measurement accuracy.   3、 Determination of blood ion content   In clinical testing, measuring the ion content in the blood is a common operation, such as measuring the concentration of calcium, potassium, and sodium plasma. Heparin lithium is recommended as an anticoagulant mainly because it has minimal interference with the determination of other ion concentrations, ensuring the accuracy of ion concentration measurement and providing important information for the diagnosis and treatment of various diseases.   4、 Fast and stable   Heparin lithium quickly plays a role in blood sample collection, ensuring that the blood does not coagulate after collection, maintaining a stable state of the sample before further testing. This is particularly important for medical staff, especially in emergency biochemical tests where time is crucial.   5、 Precautions for use   Although heparin lithium has extensive applications in multiple fields, some precautions need to be followed when using it. Firstly, heparin lithium is not a drug and cannot be used as an injection. Direct injection into humans and animals is prohibited. Secondly, the anticoagulant effect of heparin lithium is reversible, so the collection and testing of blood samples need to be completed within the specified time, usually within 6 hours. Outdated samples may lead to errors in the test results.   The quality of heparin lithium raw material is crucial when used in blood collection. Unqualified heparin lithium may affect the results of later testing. Therefore, everyone should pay attention to choosing reliable suppliers and manufacturers to obtain high-quality heparin lithium. Here we recommend Hubei Xindesheng, which can supply raw material powder with high main content and low impurities, for use by blood collection manufacturers. After repeated testing, it has high stability. If you have any interest, please feel free to contact us for purchase!

Heparin sodium and heparin lithium are two common anticoagulants that play important roles in clinical and laboratory applications. Although they are very similar in terms of names and the raw materials are in powder form, they are prepared into solutions and added to test tubes for use, but there are significant differences in chemical properties and some specific applications. Let's take a look together.   Different chemical properties   1. Different nuclear charge numbers: One of the biggest differences between heparin sodium and heparin lithium is that they contain different metal ions. Sodium heparin contains sodium ions (Na+), while lithium heparin contains lithium ions (Li+). Lithium ions have a lower nuclear charge than sodium, making them more chemically stable.   2. Differences in coagulation speed: Due to the different nuclear charge numbers between heparin lithium and heparin sodium, the interaction speed between heparin lithium and platelets (PLT) is slow. In contrast, the binding speed between heparin sodium and PLT is relatively fast, which may be unfavorable for certain laboratory applications. For example, heparin sodium is not suitable for whole blood cell analysis, as the faster aggregation speed of PLT may lead to inaccurate results.   Differences in binding mechanisms   Both heparin sodium and heparin lithium are different forms of heparin, but their binding mechanisms differ. Heparin lithium can be understood as being replaced from heparin sodium, so their effective binding ions are different.   The recommended dosage is different   In the industry standards for vacuum blood collection, there are different dosage ranges for heparin sodium and heparin lithium. Normally, there is 12-30IU of heparin sodium per milliliter of blood, but the recommended dosage range for heparin lithium is usually between 9.4IU-28IU per milliliter of blood. This difference needs to be considered in the laboratory and blood collection process to ensure the correct anticoagulant effect.   From the above, there are significant differences between heparin sodium and heparin lithium, especially in terms of chemical properties, binding mechanisms, and anticoagulant dosage. When using, attention should be paid to selecting test tubes that meet experimental requirements for blood collection or experimentation to ensure safety and effectiveness. As a manufacturer of blood vessel additives, Desheng can supply high-quality and reliable raw materials. Due to its independent warehouse, it can store in stock, and customers do not need to worry about shortages and low prices. If you have any interest, please feel free to contact us for purchase!

Heparin is a naturally occurring anticoagulant substance in mammals, which has been extracted and widely used in various medical scenarios. Heparin Lithium is a form of heparin that plays a crucial role in blood testing and clinical medicine. Because it is a polysaccharide, originally in powder form, it is often added to test tubes after preparation to prevent blood clotting. So how does it affect the blood? Let's take a look together.   Lithium heparin works:   1. Anticoagulant effect: One of the most important effects of heparin lithium is anticoagulation. It binds and activates antithrombin inhibitors, such as antithrombin III (also known as antithrombin activity enhancing substances). This action prevents platelet aggregation and activation of coagulation factors in the blood, thereby slowing down the speed of blood coagulation. Due to its anticoagulant effect, blood samples treated with heparin lithium are suitable for various biochemical tests, such as liver and kidney function measurement, blood sugar, blood lipids, etc.   2. Blood stability: In medical laboratories, heparin lithium tubes are commonly used for the extraction and preservation of blood samples, as they can prevent blood clotting and maintain the original state of blood samples. This is very important for blood testing and various biochemical tests. Medical staff can accurately analyze various parameters in the blood, ensuring the accuracy of testing.   3. Hemodialysis: Hemodialysis is a method of treating chronic kidney disease by removing waste and excess fluids from the bloodstream. Due to the unique nature of these patients' samples, anticoagulants containing heparin such as low molecular weight heparin calcium are often used, which seriously affects the extraction of serum. But using heparin lithium anticoagulant plasma for detection, the results are still accurate and effective, and according to the results, it does not affect cell volume.   Heparin lithium plays an anticoagulant role in blood sample processing, occupying an important position in both clinical medicine and laboratory research. There are also many suppliers in the market, but choosing a reliable and high-quality one for the long term is a challenge. Here, we recommend you to choose Desheng, a manufacturer that integrates research and development, production, and sales. We can supply a full range of blood collection additives, and provide one-on-one tracking services from consultation, ordering, shipping, and after-sales. If there are any problems, they can be solved promptly and properly, earning the trust of our customers. If you have any interest, please feel free to contact us for purchase!

Heparin lithium, as an anticoagulant, has a wide range of applications. Due to its natural anticoagulant properties, it plays an important role in blood sample collection and anticoagulation processes in clinical biochemical and emergency biochemical examinations. Since it is used as an anticoagulant reagent, it must also be very useful in the medical field. Let's take a specific look together.   1、 Clinical Biochemical Examination   Clinical biochemical tests include common blood tests, such as detecting ion content, liver function, kidney function, and blood lipid levels in the blood. The function of heparin lithium as an anticoagulant is to prevent premature coagulation of blood after collection, thereby ensuring the stability of blood samples. In these tests, accurate results are a prerequisite for disease diagnosis and treatment.   2、 Hemorheology project   Heparin lithium is not only used for general biochemical tests, but also widely used in hemorheology projects. Hemorheology mainly studies the flow properties of blood in blood vessels, which involves key indicators such as blood viscosity and cohesion. The addition of heparin lithium in these items can effectively prevent blood clotting and ensure measurement accuracy.   3、 Determination of blood ion content   In clinical testing, measuring the ion content in the blood is a common operation, such as measuring the concentration of calcium, potassium, and sodium plasma. Heparin lithium is recommended as an anticoagulant mainly because it has minimal interference with the determination of other ion concentrations, ensuring the accuracy of ion concentration measurement and providing important information for the diagnosis and treatment of various diseases.   4、 Fast and stable   Heparin lithium quickly plays a role in blood sample collection, ensuring that the blood does not coagulate after collection, maintaining a stable state of the sample before further testing. This is particularly important for medical staff, especially in emergency biochemical tests where time is crucial.   5、 Precautions for use   Although heparin lithium has extensive applications in multiple fields, some precautions need to be followed when using it. Firstly, heparin lithium is not a drug and cannot be used as an injection. Direct injection into humans and animals is prohibited. Secondly, the anticoagulant effect of heparin lithium is reversible, so the collection and testing of blood samples need to be completed within the specified time, usually within 6 hours. Outdated samples may lead to errors in the test results.   The quality of heparin lithium raw material is crucial when used in blood collection. Unqualified heparin lithium may affect the results of later testing. Therefore, everyone should pay attention to choosing reliable suppliers and manufacturers to obtain high-quality heparin lithium. Here we recommend Hubei Xindesheng, which can supply raw material powder with high main content and low impurities, for use by blood collection manufacturers. After repeated testing, it has high stability. If you have any interest, please feel free to contact us for purchase!

Anticoagulants are a type of reagent used for blood processing, which can delay blood clotting and help medical staff fully apply it to various biochemical tests. Heparin lithium, as a polysaccharide compound, is usually extracted from animal organs (such as pig intestinal mucosa), with an average molecular weight of around 15000 and a negative charge, which is one of its key characteristics as an anticoagulant. Below is a specific introduction to how heparin lithium acts as an anticoagulant.   The anticoagulant mechanism of heparin lithium   The anticoagulant effect of heparin lithium involves multiple mechanisms, which together ensure its anticoagulant effect:   1. Inhibition of the formation of prothrombin kinase: Heparin lithium binds to antithrombin III (AT - III) to form the heparin AT - III complex. AT - III is a serine protease inhibitor that can inactivate coagulation factors with serine protease activity, while heparin lithium promotes coagulation factor inactivation by enhancing the activity of AT - III, thereby inhibiting the formation of prothrombin kinase.   2.Interference with the function of thrombin: When it binds to AT - III, it blocks the normal activity of thrombin and further inhibits the conversion of fibrinogen to fibrin. At the same time, it can also block platelet adhesion and aggregation, thereby preventing platelet disintegration and releasing platelet factors and serotonin.   Advantages of heparin lithium anticoagulants   Compared with other anticoagulants, heparin lithium has its own unique characteristics and advantages:   1. Rapid anticoagulation: The anticoagulation effect of heparin lithium occurs immediately after contact with blood samples, making samples that urgently require anticoagulation treatment suitable for various biochemical testing items without the need for prolonged waiting.   2. Low monitoring demand: The anticoagulant effect of heparin lithium is relatively stable, and frequent observation of blood samples is usually not necessary.   3. Widely applicable: It can be used in various situations, such as liver and kidney function measurement, as well as in the diagnosis of deep vein thrombosis, pulmonary embolism, DIC and other coagulation diseases.   As an anticoagulant, heparin lithium has a wide range of applications in the medical field, and its unique anticoagulant mechanism makes it a powerful tool for dealing with various coagulation problems. As a manufacturer of heparin lithium, Desheng can provide high-quality raw material powder, which is prepared into a solution and added to the blood collection vessel for use. It not only plays a stable role, but also has a favorable raw material price! If you have any interest, please feel free to contact us for purchase!

Plasma separation is a common operation in clinical and laboratory medicine, which typically requires the use of a series of specially designed reagents and materials to ensure efficient plasma separation. Among them, the test tubes containing anticoagulant heparin lithium and separation gel are more common. So why use heparin lithium and separation gel test tubes instead of other types? This is inseparable from the role and significance of their combination.   1、 Key points of heparin lithium anticoagulation   Heparin lithium is an anticoagulant, belonging to one of the common types of heparin. Its main function in plasma separation tubes is to inhibit blood coagulation. Its anticoagulant effect is achieved by interfering with the interaction between thrombin and fibrinogen, which prevents the formation of fibrin and keeps the blood in its original state, making it easier to separate plasma. After collecting blood samples, the blood in the plasma separation tube will come into contact with heparin lithium, ensuring that the entire sample will not coagulate during the collection and separation process, and obtaining effective plasma.   2、 Effective separation of separation gel   Separation gel is another important component in the plasma separation process. It is usually located at the bottom of the plasma separation tube, and has precisely controlled density and viscosity. Under centrifugal operation, plasma will move up and float on the upper layer of the gel, while blood cells will deposit on the lower layer of the separation gel. This method not only ensures rapid separation of plasma, but also maintains the integrity of blood cells.   3、 Effect of heparin lithium for plasma separation on gel   The use of heparin lithium and separation gel ensures that blood samples can be separated efficiently and without pollution, making subsequent detection and analysis more accurate and reliable. At the same time, clinicians often need to carry out various blood tests, such as biochemical tests, disease screening, etc. The accuracy of plasma separation results also provides guarantee for clinical practice.   Heparin lithium and separation gel are indispensable components of the plasma separation tube and must be added. As reagents used in vacuum tubes, there are strict requirements on the quality of its raw materials.   As a raw material supplier for blood collection additives, Desheng has supplied to multiple blood collection enterprises with reliable and stable quality, high customer return rate, not only anticoagulants and separation gels, but also various types of products such as coagulants and silicides, with multiple selectivity and low prices. If you have any interest, please feel free to contact us for purchase!

The application of heparin lithium in blood testing is an important aspect of clinical diagnosis, playing a crucial role in blood collection and processing. Due to its extraction from pig intestinal mucosa, it is a mucopolysaccharide containing sulfate groups and a biologically active substance with strong negative charges, which has anticoagulant effects both in vivo and in vitro. Below, we will delve into the application of heparin lithium in blood.   Heparin lithium coagulation mechanism   Heparin lithium has an impact on all three stages of the coagulation process. Firstly, it binds to antithrombin III (AT - III) and forms a heparin AT - III complex, inactivating coagulation factors with serine protease activity, thereby inhibiting the formation of prothrombin kinase and preventing blood coagulation. In addition, it binds to the active center of thrombin at the reaction site of AT - III to form a stable thrombin antithrombin complex, which inactivates thrombin, inhibits the conversion of fibrinogen to fibrin, and also prevents platelet adhesion and aggregation.   Application fields of heparin lithium   1. Plasma separation tube: Heparin lithium is added to the PST plasma separation tube, which can achieve rapid separation of plasma. This is an ideal choice for electrolyte testing and is also suitable for routine plasma biochemical testing and emergency plasma biochemical testing.   2. Liver function examination: Heparin lithium is used in liver function examinations, such as detecting hepatitis, liver cancer, fatty liver, etc. The use of heparin lithium anticoagulation can effectively prevent blood clotting and improve examination efficiency.   3. Hemorheological testing: When detecting cardiovascular and cerebrovascular diseases, blood may exhibit abnormal viscosity, and heparin lithium can be used for anticoagulation. In addition, it is also used in some special projects, such as arterial blood gas analysis, electrolyte and calcium ion detection processes.   4. Blood gas and erythrocyte sedimentation rate detection: Heparin lithium is present in anticoagulant tubes, interfering with the coagulation process and prolonging the coagulation time of the sample. Therefore, it is also suitable for items such as blood gas analysis and erythrocyte sedimentation rate detection.   Precautions for use   1. The heparin lithium in the blood collection vessel needs to be thoroughly mixed with the blood sample to avoid partial coagulation.   2. The anticoagulant effect of heparin lithium is not irreversible, so the samples after blood collection should undergo relevant testing items as soon as possible, otherwise it will affect the test results.   3. Pay attention to the blood collection volume of heparin lithium tubes. Generally, 15-20IU of heparin lithium can anticoagulate 1ml of blood.   Heparin lithium plays an important role in clinical blood processing, and its anticoagulant properties make it an indispensable reagent in the medical field. As a professional manufacturer of heparin lithium, Desheng can provide analytical grade heparin lithium raw materials for preparation and use by blood collection manufacturers. At the same time, it has technical guidance and one-on-one service to timely solve customer problems. If you have any interest, please feel free to contact us for purchase!