China Wuhan Desheng Biochemical Technology Co., Ltd Company News

In today's rapidly advancing technological innovation, the biopharmaceutical and medical device industries, as important pillars of Healthy China, are flourishing at an unprecedented speed. As a leading global biotechnology and diagnostic product expo, China International Medical Equipment Fair (CACLP) not only gathers top medical technology companies from home and abroad, but also serves as a forefront for industry exchange, cooperation, and innovation. In 2025, the CACLP exhibition is about to kick off, and Hubei Xindesheng Material Technology Co., Ltd. (hereinafter referred to as "Xindesheng") will shine with its latest scientific research achievements and cutting-edge technologies, jointly painting a new chapter in medical technology. Innovation leads, scientific research empowers Since its establishment, Xindesheng has always adhered to the corporate philosophy of "innovation driven development, technology serving society", deeply rooted in the field of biomaterials and technology, and committed to the research and development of high-quality and high-performance medical diagnostic reagents and biomaterials products. The company has its own professional R&D team, which continuously breaks through technical barriers through continuous R&D investment and technological innovation, providing high-quality reagents for clinical testing, immunoassay and other technical fields. At the upcoming CACLP exhibition, Xindesheng will showcase its latest research achievements in molecular diagnosis, immune diagnosis and other fields, including high-sensitivity detection reagents. These innovative products not only improve diagnostic efficiency and accuracy, but also open up new paths for early detection of diseases. Quality first, service foremost Quality is the lifeline of an enterprise, and Xindesheng is well aware of this. The company has established a strict quality management system, from raw material procurement to production and processing, and then to finished product inspection, every link follows relevant standards to ensure the excellence and stability of product quality. At the same time, Xindesheng attaches great importance to customer service experience and has built a comprehensive and multi-level service network, including technical support, customized solutions, and rapid response mechanisms, aiming to provide customers with the most intimate and professional service experience. At the CACLP exhibition, Xindesheng will set up a dedicated consulting service area, inviting industry experts to answer customer questions on-site and jointly explore cooperation opportunities. Green production, sustainable development Faced with the challenges of global environmental protection and sustainable development, Xindesheng actively responds to the national call and integrates the concept of green development into every aspect of enterprise operation. The company adopts environmentally friendly materials, optimizes production processes, reduces energy consumption and waste emissions, and strives to achieve a win-win situation of economic and environmental benefits. During the CACLP exhibition, Xindesheng will showcase its achievements in green production, including environmentally friendly packaging materials, energy-saving production technologies, etc., aiming to convey the positive energy of green development to the industry and lead the industry towards a more environmentally friendly and sustainable direction. Looking to the future, win-win cooperation Looking ahead to the CACLP exhibition in 2025, Xindesheng not only looks forward to showcasing its innovative strength and technological achievements, but also hopes to establish broader cooperative relationships with domestic and foreign peers, research institutions, and medical institutions through this platform. The company firmly believes that through resource sharing and complementary advantages, we can jointly promote the innovative development of the biopharmaceutical and medical device industries, and contribute to the progress of global public health. New Desheng cordially invites friends from all walks of life to attend the exhibition site, seek common development plans, and create a brilliant future together. At the upcoming CACLP exhibition in 2025, Hubei Xindesheng Material Technology Co., Ltd. will welcome every visitor with innovative products, excellent quality, green concepts, and an open attitude. Let's look forward to the wonderful display of Xindesheng at this exhibition, witnessing the arrival of a new era in medical technology!

In the fields of biochemistry and molecular biology, enzyme activity detection is the core means of measuring whether biochemical processes in organisms are operating normally. However, in practical operation, there is often a problem of low enzyme activity, which makes it difficult for traditional detection methods to accurately capture these weak signals. In recent years, the chromogenic substrate HDAOS reagent (N - (2-hydroxy-3-sulfopropyl) -3,5-dimethoxyaniline sodium salt) has emerged in the field of enzyme activity detection, especially in low enzyme activity detection, due to its unique chemical structure and excellent performance. Basic features of HDAOS HDAOS, as a highly water-soluble aniline derivative, has high stability, sensitivity, and selectivity, which enable it to accurately capture weak signals in enzyme activity detection and provide reliable measurement results even when enzyme activity is low. 1. High stability: HDAOS exhibits good stability during storage and use, and is not easily oxidized or decomposed, ensuring the accuracy and reliability of detection results. Even after long-term use and storage, its performance remains stable, which is crucial for long-term monitoring and repeated experiments. 2. High sensitivity: HDAOS reacts rapidly with oxidants such as hydrogen peroxide and can form stable color reactions in a short period of time. This rapid and stable color change provides a solid foundation for enzyme activity detection. Even at low enzyme activity, HDAOS can capture small color changes with its high sensitivity, achieving precise measurement. 3. High selectivity: HDAOS has extremely high selectivity for hydrogen peroxide and can accurately determine the concentration of hydrogen peroxide in complex samples without interference from other molecules. This high selectivity ensures that enzyme activity detection can accurately reflect the activity of the target enzyme, avoiding interference from other enzymes or compounds, and providing accurate measurement results even in the presence of low enzyme activity and interfering substances. Application of HDAOS in Enzyme Activity Detection In enzyme activity detection, HDAOS serves as a chromogenic substrate or indicator, and its basic principle is to undergo an oxidation reaction in the presence of hydrogen peroxide or other oxidants to generate colored products. The color change is directly proportional to the amount of hydrogen peroxide or other oxidation products produced in enzyme catalyzed reactions, indirectly reflecting the level of enzyme activity. 1. Catalase activity detection: Catalase (CAT) is an important antioxidant enzyme in organisms, which can catalyze the decomposition of hydrogen peroxide into water and oxygen, protecting cells from oxidative damage. Using HDAOS as a chromogenic substrate, it reacts with hydrogen peroxide under the catalysis of peroxidase (such as horseradish peroxidase HRP) to generate stable purple or blue dyes. By measuring the absorbance of the reaction product, the concentration of hydrogen peroxide can be calculated to evaluate the activity of catalase. This method is easy to operate, fast, and has high sensitivity and accuracy. 2. Indirect detection of other enzyme activities: HDAOS can also be combined with other enzyme systems to indirectly evaluate related enzyme activities by monitoring changes in hydrogen peroxide or other oxidation products produced during the reaction process. For example, in the glucose oxidase (GOD) system, glucose is oxidized to gluconic acid under GOD catalysis, while producing hydrogen peroxide. Hydrogen peroxide reacts with HDAOS catalyzed by HRP to produce colored products. By measuring the absorbance of the product, the glucose concentration can be calculated, indirectly reflecting the activity of GOD. This method has a broad application prospect in diabetes diagnosis, blood glucose monitoring and other fields. The advantages of HDAOS in low enzyme activity detection 1. High sensitivity capture of weak signals: HDAOS reacts rapidly and stably with oxidants such as hydrogen peroxide, providing a reliable basis for low enzyme activity detection. Even at low enzyme activity, small color changes can be captured with high sensitivity, achieving precise measurement. 2. High selectivity reduces interference: HDAOS's high selectivity towards hydrogen peroxide ensures the accuracy of enzyme activity detection, allowing for accurate determination of hydrogen peroxide concentration even in complex samples without being affected by it. Conclusion In summary, the chromogenic substrate HDAOS exhibits accurate measurement ability in low enzyme activity detection, and its high stability, sensitivity, and selectivity make it outstanding in the field of enzyme activity detection. By combining with other enzyme systems, HDAOS can indirectly evaluate the activity of related enzymes, providing strong support for research and diagnosis in biomedical, environmental monitoring, and food safety fields. With the continuous advancement of technology and the expansion of application fields, HDAOS is expected to play an important role in more fields, providing more accurate and reliable tools for life science research and clinical diagnosis. As a professional manufacturer of chromogenic substrate, Desheng offers a complete range of products, including corresponding TOOS, TOPS, ADOS, ADPS, MAOS, etc., which can provide customers with one-stop purchasing services. Due to 18 years of production experience, the product quality has been widely recognized by the market, so in recent years, we have continuously expanded overseas and sold our products to countries around the world. If you have relevant purchasing intentions, please click on the website for consultation!

The China International Laboratory Medicine and Blood Transfusion Instrument Reagent Expo (CACLP) in 2025 is about to kick off. CACLP is the annual event of the in vitro diagnostics (IVD) industry. How can IVD professionals gain something from this grand event? It is a question worth pondering deeply. Here are some practical methods and strategies for participating in exhibitions to help you achieve success in 2025CACLP. 1, Accurately locate and clarify key visiting areas Take some time to carefully browse the exhibition map and clearly mark the exhibition areas that are closely related to your business or research field. For example, professionals engaged in molecular diagnostics should pay close attention to booths related to molecular diagnostic technology, which may showcase new gene sequencing equipment, PCR reagents, and cutting-edge molecular diagnostic technologies. After identifying key areas, targeted visits can avoid blindly wandering around the exhibition, save time and energy, and obtain valuable information for oneself. 2, Actively participate in forums and lectures to acquire cutting-edge knowledge The various forums, lectures, and seminars held during the exhibition are a gathering place for industry wisdom. The speakers of these activities are often experts, scholars, and entrepreneurs in the industry, who bring content covering new research findings, market trends, and policy interpretations. Get the schedule of forums and lectures in advance, and select relevant activities based on your interests and needs. Actively participating in these activities not only broadens one's horizons, but also enables interaction and communication with the speaker and other attendees. 3, In depth communication to gain professional insights from exhibitors Every exhibitor is a participant in the industry, with their own insights into market changes, technological developments, and customer needs. When communicating with them, boldly raise your own questions and concerns, whether it is about product performance, application scenarios, or industry development trends, you can obtain professional opinions and suggestions from them. 4, Observe competitors and gain insight into the market competition situation At the exhibition, the performance of competitors is an important window to observe the market competition situation. Pay attention to their product displays, promotional strategies, and customer interaction methods. From product displays, one can understand the product advantages and innovation points of competitors, compare their own company's products, and identify gaps and advantages; The promotional strategy can reflect their market positioning and promotion ideas; Customer interaction can help us understand customers' attention and feedback on competitor products. 5, Peer exchange, common progress The exhibition is a platform that gathers domestic and foreign IVD peers, taking advantage of this opportunity to exchange experiences and insights with peers from different regions. Colleagues have different practical experiences and innovative ideas in their respective fields. Through communication, they can learn from each other and broaden their horizons. 6, Collect data and samples to provide a basis for subsequent learning and analysis Don't miss the opportunity to collect various promotional materials, product samples, and technical documents during the exhibition. These materials are valuable gains from participating in the exhibition, as they provide detailed records of exhibitors' product information, technical parameters, and application cases. Sort and categorize these materials as a basis for subsequent learning and analysis. After the exhibition, one can delve into these materials to further understand the details of the products and technologies, providing reference for the company's procurement decisions, product development, and market expansion. The CACLP event in 2025 provides a platform for IVD professionals to learn, exchange, and collaborate. By clarifying key visiting areas, actively participating in forum lectures, engaging in in-depth exchanges with exhibitors and peers, and collecting data samples, one can gain rich knowledge and information at this grand event, bringing new opportunities for the development of their own enterprise. We look forward to every IVD person gaining a lot and reaching new heights in 2025CACLP.

In the vast field of biochemistry, the new Trinder's reagent serves as an important detection tool, providing researchers with intuitive, accurate, and rapid quantitative analysis methods. Among them, ADPS reagent (N-ethyl-N - (3-sulfopropyl) -3-methoxyaniline sodium salt) plays an indispensable role in enzyme activity determination as a highly efficient and sensitive novel Trinder's reagent. This article will delve into the physicochemical properties of ADPS, application examples in enzyme activity determination, advantages and challenges, as well as future development trends, in order to provide useful references for research in related fields. Physical and chemical properties of ADPS ADPS is a highly water-soluble derivative of aniline, and the sulfonic acid groups in its molecular structure endow it with good solubility and stability. This characteristic enables ADPS to maintain relatively stable colorimetric performance at different pH values, making it an ideal choice for enzyme activity assays. In addition, the color development mechanism of ADPS involves multiple types of chemical reactions, such as oxidation-reduction reactions, acid-base reactions, etc. These reactions not only cause changes in color, but may also be accompanied by changes in physical properties such as absorbance and fluorescence intensity. These changes in properties provide rich detection methods for enzyme activity assays. Application examples of ADPS in enzyme activity determination 1. Determination of glucose oxidase activity Under the catalysis of glucose oxidase, glucose is oxidized to form gluconic acid and hydrogen peroxide. Hydrogen peroxide, as a key substance, undergoes coupled oxidation reaction with ADPS under the catalysis of horseradish peroxidase (HRP), generating red quinone imine compounds. By measuring the absorbance changes of the reaction products, the activity of glucose oxidase can be indirectly calculated. This method not only has high sensitivity, but also has good accuracy, which provides strong support for the diagnosis of diabetes and other diseases. 2. Determination of lactate dehydrogenase activity Lactate dehydrogenase can catalyze the reduction of pyruvate to lactate, while also producing hydrogen peroxide. Under the catalysis of HRP, hydrogen peroxide reacts with ADPS to produce colored products. By measuring the color intensity of the reaction product, the activity level of lactate dehydrogenase can be indirectly reflected. This method has wide application value in fields such as tumor diagnosis and exercise physiology. 3. Other enzyme activity assays In addition to the two enzymes mentioned above, ADPS can also be used to measure the activity of various other enzymes, such as cholinesterase and glutathione peroxidase. These enzymes play important physiological functions in the body, and accurate determination of their activity is of great significance for the diagnosis and treatment of diseases. The advantages and challenges of ADPS in enzyme activity determination 1. Advantages (1) High sensitivity: ADPS can quickly detect small changes in acidity or alkalinity in the reaction system, even at extremely low concentrations of the substance being tested, and accurately reflect them through color changes. (2) High stability: The sulfonic acid groups in the ADPS molecular structure enable it to exhibit good solubility and stability in aqueous solutions, and maintain relatively stable color development performance at different pH values. (3) Easy to use: ADPS has good water solubility and can be easily formulated into solutions for use. In the experiment, a significant color change can be observed by simply adding ADPS solution to the reaction system and then adding a color developer. (4) Wide applicability: ADPS can be applied to various reaction systems, including various biochemical reactions. ADPS can be used not only for qualitative analysis but also for quantitative analysis in fields such as medical research and environmental monitoring. Challenge (1) Specificity: Although ADPS exhibits high sensitivity in enzyme activity assays, its specificity still needs to be further improved. In practical applications, it is necessary to avoid interference from other substances to ensure the accuracy of the measurement results. (2) Stability: Although ADPS has good stability, it may still degrade due to factors such as light and temperature during long-term storage or transportation. Therefore, it is necessary to conduct quality checks on ADPS before use to ensure its stability. Conclusion In summary, the new Trinder's reagent ADPS has unique application value and broad development prospects in enzyme activity determination. However, in practical applications, attention still needs to be paid to issues such as specificity, stability, and safety. In the future, with the continuous advancement of biotechnology and the increasing market demand, the research and application of ADPS will be more in-depth and extensive. Desheng is a manufacturer of the new Trinder's reagents, currently producing a wide range of product types, including ADPS, which can be used in various fields and can also be customized according to the company's own usage. At the same time, the company is equipped with its own R&D team, which can provide a series of technical services for subsequent products. If you have any relevant needs, please click on the website or call to inquire about details!  

Biological buffer BES buffer (N, N-bis (2-hydroxyethyl) -2-aminoethanesulfonic acid) is a chemical substance with important application value in the fields of biochemistry, molecular biology, and organic synthesis. This article aims to explore the multiple roles of BES in organic synthesis, and conduct in-depth analysis from the aspects of buffering performance, chemical stability, reaction pH control, intermediate stability, and protection of bioactive substances. Chemical Structure and Properties of BES BES is a white powder. Its chemical structure contains sulfonic acid groups and aminoethyl groups, which endow BES with unique buffering properties and chemical stability. BES can maintain stability over a wide range of temperatures and pH, which enables it to exhibit excellent buffering effects in various organic synthesis reactions. The buffering effect of BES in organic synthesis BES, as an effective buffering agent, mainly stabilizes the pH value in organic synthesis by adjusting the concentration of hydrogen ions in the solution, thus playing a buffering role. This buffering effect is crucial for organic synthesis reactions, as many reactions require specific pH conditions to be carried out. 1. Control the pH value of the reaction: In organic synthesis, pH value is a key factor. BES can achieve precise control of the reaction pH by adjusting the concentration of hydrogen ions in the solution. This not only ensures the smooth progress of the reaction, but also improves the purity and yield of the product. For example, in peptide synthesis, pH value is a key factor. By using BES as a buffer, the pH value of the reaction can be effectively controlled, thereby improving the efficiency and purity of peptide synthesis. 2. Stable reaction intermediates: In organic synthesis, it is often necessary to handle some unstable intermediates. These intermediates are often very sensitive to pH values, and a slight mistake can lead to reaction failure. The use of BES can effectively stabilize these intermediates, thereby improving the stability and success rate of the reaction. This stability is particularly important for synthesizing complex organic molecules, as the synthesis of complex molecules often requires multiple steps, each of which requires strict control of reaction conditions. Chemical stability and wide application of BES Another significant advantage of BES in organic synthesis is its chemical stability. BES can maintain stability over a wide range of temperatures and pH, and is not easily affected by factors such as temperature and light. This stability ensures the stability and repeatability of the reaction, enabling BES to exhibit good buffering effects in various organic synthesis reactions. 1. Adapt to multiple reaction conditions: Due to its excellent chemical stability, BES can adapt to various organic synthesis reaction conditions. It can maintain its buffering performance and provide a stable pH environment for the reaction. 2. Improve product quality: By precisely controlling the pH value of the reaction, BES can significantly improve the quality and purity of the product. This is of great significance for drug research and material preparation in the field of organic synthesis. High quality products not only enhance their market competitiveness, but also provide a reliable material foundation for subsequent application research. The role of BES in the protection of bioactive substances In organic synthesis involving bioactive substances, such as enzyme catalyzed reactions or cell culture, BES can effectively maintain the pH stability of the reaction system, thereby protecting bioactive substances from pH changes. This is crucial for maintaining enzyme catalytic activity, cell growth, metabolism, and other biological processes. 1. Protecting enzyme catalytic activity: In enzyme catalyzed reactions, enzymes typically require specific pH conditions to exhibit optimal catalytic activity. The application of BES can ensure that the pH value of the reaction system is stable within the optimal range of the enzyme, thereby improving the catalytic efficiency of the enzyme and the yield of the product. This is of great significance for applications such as biotransformation and biocatalysis in the field of enzyme engineering. 2. Maintain the cell growth environment: During cell culture, both cell growth and metabolism need to be carried out in a specific pH environment. BES, as a buffering agent in cell culture medium, can maintain the pH stability of the medium, thereby providing a suitable environment for cell growth and reproduction. This is of great significance for research in fields such as cell biology and tissue engineering. 5, Conclusion In summary, the biological buffer BES plays multiple roles in organic synthesis. Its unique buffering performance and chemical stability make BES an indispensable buffer in various organic synthesis reactions. Through precise control of reaction pH, stabilization of reaction intermediates, and protection of bioactive substances, BES provides strong support for research and application in the field of organic synthesis. As a BES raw material manufacturer, Desheng has advanced production technology and strict quality management system. The BES raw materials produced have high purity and stable quality, which can meet customers' demand for high-quality products. At the same time, Desheng focuses on technological innovation and research and development, continuously optimizing production processes, improving product performance, and reducing costs. If you have any relevant needs, please click on the website to inquire about details and purchase!

In the fields of biochemistry and clinical testing, the chromogenic substrate MAOS reagent (N-ethyl-N - (2-hydroxy-3-sulfopropyl) -3,5-dimethylaniline sodium salt) has attracted much attention as a novel Trinder's reagent due to its high sensitivity and specificity. However, to fully leverage the performance advantages of MAOS, proper storage conditions are crucial. Especially, avoiding direct sunlight and humid environments is key to ensuring the long-term stability and effectiveness of MAOS. This article will delve into why it is necessary to avoid direct sunlight and humid environments when storing MAOS, as well as the scientific principles and practical significance behind this requirement. MAOS storage requirements MAOS, as a highly sensitive chromogenic substrate, has a direct impact on its chemical stability and reactivity under storage conditions. The ideal storage environment should ensure the integrity of the MAOS molecular structure and prevent its degradation or deterioration due to external factors. Specifically, when storing MAOS, the following key factors should be considered: temperature, lighting, and humidity. The importance of avoiding direct sunlight 1. Photosensitivity: MAOS is extremely sensitive to light, and prolonged exposure to sunlight or strong light can accelerate its decomposition process. This decomposition not only causes color changes in MAOS, but more importantly, it reduces its reactivity, thereby affecting the accuracy of the detection results. Therefore, it is crucial to store MAOS in completely dark containers, such as brown glass bottles or reagent bottles wrapped in aluminum foil, to reduce the potential impact of light on it. 2. Chemical stability: Light exposure may also cause chemical bond breakage within MAOS molecules, which further reduces their reactivity. Keeping MAOS stored in a dark environment helps maintain the stability of its chemical structure, thereby extending its lifespan. The necessity of moisture-proof environment 1. Moisture sensitivity: MAOS is also sensitive to humidity. A humid environment may trigger the oxidation reaction of MAOS, generating unwanted products that may affect its subsequent color reaction, thereby reducing the accuracy of detection. In addition, moisture may cause MAOS powder to clump or the solution to deteriorate, further affecting its effectiveness. 2. The importance of maintaining dryness: To maintain the dry state of MAOS and protect it from moisture damage. Meanwhile, ensuring the sealing of storage containers is also one of the key measures for moisture prevention. Suggested storage conditions To ensure the stability and effectiveness of MAOS during storage and use, the following are some practical recommendations: 1. Maintain a dry environment: Ensure a dry storage environment and prevent moisture from entering the reagent bottle. The use of desiccants or dehumidification devices can help maintain the dryness of storage spaces. 2. Sealed storage: For MAOS powder and solution, they should be kept sealed to avoid moisture and clumping caused by contact with air. 3. Regular inspection: Regularly check the storage status of MAOS to ensure that it has not deteriorated or degraded. If any abnormalities are found, new reagents should be replaced immediately. The impact of storage conditions on MAOS applications The correct storage conditions are crucial for the application of MAOS. Improper storage methods may lead to a decrease or deterioration of MAOS activity, thereby affecting its accuracy and reliability in biochemical testing and clinical diagnosis. For example, in the determination of biochemical indicators such as blood glucose, blood lipids, or liver function, the use of deteriorated MAOS may lead to test results deviating from true values, thereby affecting doctors' diagnosis and treatment decisions. Conclusion In summary, the storage of the chromogenic substrate MAOS should be strictly avoided from direct sunlight and humid environments. This requirement is not only based on the sensitivity of MAOS to light and humidity, but also to ensure its stability and effectiveness during storage and use. By selecting appropriate storage containers, controlling storage temperature, maintaining a dry environment, and sealing storage, we can effectively extend the storage life of MAOS and improve its effectiveness. Desheng Technology has been committed to the research and development, production, and sales of various chromogenic substrate, with products sold both domestically and internationally. Especially TOOS, MAOS, TOPS have always been trusted and praised by customers. The MAOS oxidizing chromogen reagent produced by Desheng is a highly water-soluble, stable aniline analog with a wide pH range for coloring and oxidation reactions, and a purity of over 99%. Due to the rigorous production process, it can ensure that the appearance of the white powder is free of impurities. It can also be packaged according to customer needs. If you have purchasing requirements, you can directly contact the customer manager on the official website.

Biological buffering agents play a crucial role in various fields such as biochemistry, molecular biology, and cosmetic science. They can maintain the acid-base balance of the reaction system, protect the structure and function of biomolecules, and ensure the accuracy and reliability of experimental results. Among numerous biological buffering agents, Bicine (N, N-dihydroxyethylglycine) has attracted widespread attention and research due to its unique chemical structure and properties, particularly its ability to maintain charge balance in different pH environments. This article will delve into the characteristics of Bicine, explain its importance, and analyze its broad significance in practical applications. 1, Chemical Structure and Properties of Bicine Bicine is a zwitterionic buffering agent, endowed with unique buffering abilities by its amino and carboxyl groups in its chemical structure. In solution, Bicine can maintain charge balance by accepting or releasing protons according to different pH environments. When the solution is acidic, the amino portion of Bicine can accept protons and form positively charged ions; When the solution is alkaline, its carboxyl group can release protons and form negatively charged ions. The ability to maintain charge balance under different pH conditions makes Bicine an ideal biological buffer. 2, The mechanism of Bicine maintaining charge balance in different pH environments The mechanism by which Bicine maintains charge balance in different pH environments is mainly based on the weak electrolyte ionization balance in its molecular structure. In solution, Bicine molecules exist in ionization equilibrium, which is the proton transfer equilibrium between amino and carboxyl groups. When acid or base is added to the solution, this equilibrium is disrupted, but Bicine can re-establish equilibrium by absorbing or releasing protons, thereby maintaining the pH stability of the solution. Specifically, when the solution is acidic, the concentration of hydrogen ions in the solution increases, and the amino portion of Bicine can accept these hydrogen ions to form positively charged ions, thereby slowing down the rate of solution acidification. On the contrary, when the solution is alkaline, the concentration of hydroxide ions in the solution increases, and the carboxyl group of Bicine can release protons to form negatively charged ions, thereby slowing down the rate of solution alkalization. This ability to maintain charge balance by accepting or releasing protons enables Bicine to provide effective buffering over a wide pH range (typically 7.6-9.0). 3, The importance of maintaining charge balance in Bicine The ability of Bicine to maintain charge balance in different pH environments is of great significance for biochemical and molecular biology experiments. Firstly, it can provide a stable pH environment for biomolecules, protecting their structure and function from changes in acidity or alkalinity. Biomolecules such as enzymes and proteins are extremely sensitive to changes in pH, and environments that are too acidic or too alkaline can lead to structural damage and loss of function. The addition of Bicine can ensure that biomolecules function under optimal pH conditions, thereby improving the accuracy and reliability of experiments. Secondly, Bicine's charge balancing ability also helps maintain the ion strength and osmotic pressure stability of biochemical reaction systems. Ionic strength and osmotic pressure are important factors that affect the rate and equilibrium of biochemical reactions. The addition of Bicine can ensure the stability of ion concentration in the reaction system and provide an optimal ion environment for biochemical reactions. Meanwhile, Bicine can also regulate the osmotic pressure of the system, making it closer to the physiological environment inside the organism, thereby improving the efficiency and stability of biochemical reactions. 4, The application of Bicine in cosmetic science In addition to the fields of biochemistry and molecular biology, Bicine also has broad application prospects in cosmetic science. The acidity and alkalinity of cosmetics not only affect the stability of the product, but also directly affect the safety and user experience of the product. Bicine, as an excellent biological buffering agent, can maintain the acid-base balance of cosmetics and protect the skin barrier from damage. At the same time, the addition of Bicine can also improve the skin feel of cosmetics, making them smoother and more delicate, enhancing the user experience. In addition, Bicine also has the ability to chelate heavy metal ions, which can further protect skin health. 5, Conclusion In summary, Bicine, as a biological buffering agent that maintains charge balance in different pH environments, has shown broad application prospects in various fields such as biochemistry, molecular biology, and cosmetic science. Its unique chemical structure and properties enable it to provide effective buffering over a wide pH range, protect the structure and function of biomolecules, and maintain the ion strength and osmotic pressure stability of biochemical reaction systems. Hubei Xindesheng Material Technology Co., Ltd. is a manufacturer of bicine buffering agents. The company was established in 2005 and has been committed to the research and development of biological buffering agents for more than ten years. Not only has it established its own research and development team, but it has also achieved important results in this field. Currently, the company produces and sells more than 30 types of biological buffering agents, with a complete range of products. Welcome customers who are interested in purchasing to inquire and learn more!

In the field of in vitro diagnostics (IVD), the China International Conference on Laboratory Medicine and Blood Transfusion Instruments and Reagents (CACLP) is undoubtedly an annual industry event. The upcoming 22nd CACLP is highly anticipated. This grand event will be held from March 22nd to 24th, 2025 at the Hangzhou Convention and Exhibition Center. Over 1200 companies, including Hubei Xindesheng Material Technology Co., Ltd., will participate, bringing a feast of technology and products to the industry. The Importance and Influence of CACLP Since its establishment in 1991, CACLP has become a flagship exhibition in the field of IVD at home and abroad after years of development and precipitation. It integrates exhibition display, academic exchange, brand promotion, supply chain construction, investment attraction, and cooperation negotiation, and is an important indicator for the development of the IVD industry. Every CACLP closely follows the new trends in the development of the in vitro diagnostics industry, providing a platform for communication and cooperation among enterprises, experts, scholars, and others in the industry, promoting technological innovation and market expansion in the entire IVD industry. Over the past twenty exhibitions, CACLP has witnessed and driven the rapid development of the IVD industry. From early simple product displays to now covering cutting-edge technology seminars, industry university research cooperation and docking, CACLP continues to upgrade and inject momentum into the development of the industry. It has promoted communication and cooperation between domestic and foreign enterprises, accelerated the promotion and application of new technologies and products, and played an important role in the promotion, sales, conversion, and improvement of IVD products. Highlights and Features of the 22nd CACLP 1. Strong lineup of exhibiting companies: This exhibition attracted over 1200 companies, covering various fields of the IVD industry. Not only are there established giants in the industry, but there are also numerous emerging innovative enterprises. These enterprises will bring their own new products and technologies, showcasing the innovative achievements and development trends of the IVD industry. 2. In depth domestic and international exchanges: The exhibition will invite exhibition groups from multiple countries and regions to showcase excellent diagnostic technologies, present cutting-edge trends in domestic and international industries, and bring rich market information and cooperation opportunities. 3. Rich on-site activities: During the exhibition, multiple academic forums, technical seminars, new product launches, and other events will be held. These activities will invite experts, scholars, and business representatives from the industry to conduct in-depth discussions on hot topics in the IVD industry, such as new breakthroughs in medicine and molecular diagnostic technology, and the development trends of POCT. They will provide participants with opportunities for learning and communication, promoting knowledge sharing and technological innovation. Hubei Xindesheng Material Technology Co., Ltd. Exhibition Highlights Hubei Xindesheng Material Technology Co., Ltd. was established in 2005 and is located in Guanggu United Science and Technology City, Huarong District, Ezhou City, Hubei Province. The company focuses on the research and development, production, and sales of polymer materials and biologics, and has accumulated rich experience and technical strength in the upstream raw material field of IVD. Its products cover multiple categories such as biological buffering agents, chemiluminescence reagents, and chromogenic substrates, and have been widely recognized in the market for their quality and excellent performance. At this CACLP, Xindesheng will showcase its core products and new research and development achievements. For example, the biological buffering agents produced by it, such as Tris, Bicine, Caps, etc., have the characteristics of high purity and good stability, and are widely used in biochemical experiments and in vitro diagnostic reagents; Chemiluminescence reagents such as luminol and acridine esters have high sensitivity and strong luminescence efficiency, providing strong support for chemiluminescence immunoassay; Chromogenic substrates (new Trinder's reagents) such as TOOS, TOPS, ADOS, etc. play an important role in biochemical testing and can accurately detect various clinical indicators. New Desheng will leverage this exhibition platform to engage in in-depth technical exchanges and cooperation negotiations with other enterprises, research institutions, and others in the industry. Professional personnel from the company will answer visitors' questions and share products at the booth. At the same time, Xindesheng also hopes to seek more cooperation opportunities through exhibitions to jointly promote the development of the upstream raw material industry of IVD. As the exhibition approaches, let us look forward to the wonderful presentation of this industry event together.

Gel filtration chromatography, also known as molecular sieve chromatography or steric exclusion chromatography, is a separation technology based on molecular size differences. In the research of biochemistry and molecular biology, gel filtration chromatography is widely used in the separation and purification of biological macromolecules such as proteins and peptides. In this process, the biological buffer BES plays an indispensable role. This paper will discuss the application and importance of BES buffer in gel filtration chromatography. Basic principles of gel filtration chromatography The principle of gel filtration chromatography is mainly based on the diffusion and screening of molecules in gel particles. When the sample solution passes through the gel column, molecules of different sizes will be blocked to varying degrees. Because of its large diameter, macromolecular substances are not easy to enter the pores of gel particles, so they move downward along the gap between gel particles. The process is short, the migration speed is fast, and the path is short, so they flow out of the chromatographic column first; In addition to diffusing in the gap between gel particles, small molecules can also enter the micropores of gel particles, that is, into the gel phase. During the downward movement, small molecules diffuse from one gel particle to the gap between particles and then enter another gel particle. In this way, they constantly enter and diffuse. The downward movement speed of small molecules lags behind that of large molecules, so that the large molecules in the sample flow out of the chromatographic column first, the medium molecules flow out later, and the smallest molecules flow out last. This phenomenon is also called molecular sieve phenomenon. Buffer Characteristics of BES and Its Role in gel Filtration Chromatography BES, as a zwitterionic buffering agent, has excellent buffering performance and biocompatibility. It can effectively absorb or release protons (H+) within a wide pH range (usually 6.0~8.5), thereby maintaining the relative stability of the solution pH. This characteristic makes BES an ideal pH regulator in biochemical experiments. In gel filtration chromatography, the main role of BES is to maintain the stability of the pH value of the solution. Due to the fact that the function and activity of many biomolecules depend on specific pH environments, it is crucial to maintain a stable pH value of the solution during separation and purification processes. BES, as a buffer solution, can absorb or release protons to cope with small changes in pH in the solution, thereby ensuring the stability and activity of biomolecules during the separation process. In addition, BES can also adjust the ionic strength of the solution. Ion strength is one of the important factors that affect the interaction between protein and gel particles. By adjusting the concentration of BES, the ion strength of the solution can be controlled, thereby affecting the elution speed and separation efficiency of proteins. Appropriate ionic strength can enhance the interaction between protein and gel particles, extend the elution time of protein, and improve the separation efficiency. Application of BES in gel filtration chromatography 1. Optimize separation conditions When using gel filtration chromatography to separate and purify biomacromolecules, it is necessary to select appropriate separation conditions according to the characteristics of target molecules and experimental needs. BES, as a buffer solution, can optimize separation conditions by adjusting parameters such as concentration, pH value, and ionic strength. For example, for some specific proteins, increasing the concentration of BES and reducing the pH value can enhance their interaction with gel particles and improve the separation efficiency. 2. Improve separation purity Since gel filtration chromatography is based on molecular size, there may be some impurity molecules with similar size to the target molecules in the separation process. These impurity molecules may compete with the target molecules for the adsorption sites of gel particles, thus affecting the separation purity. By using BES as buffer solution, the ionic strength and pH value of the solution can be adjusted, so as to change the interaction between target molecules and impurity molecules and gel particles and improve the separation purity. 3. Protect the structure and function of biomolecules In the process of gel filtration chromatography, the structure and function of biomacromolecules may be affected by physical and chemical factors. BES, as a buffer solution, can provide a stable and suitable pH environment to protect the structure and function of biomolecules from being affected. In addition, BES can also bind with some metal ions to form stable metal ion complexes, thereby avoiding the destructive effect of metal ions on biomolecules. Conclusion In conclusion, the biological buffer BES has extensive application value in gel filtration chromatography. By adjusting parameters such as concentration, pH value, and ionic strength reasonably, separation conditions can be optimized, separation efficiency and purity can be improved, and the structure and function of biomolecules can be protected. As a BES raw material manufacturer, Desheng has advanced production technology and strict quality management system. The BES raw materials produced have high purity and stable quality, which can meet customers' demand for high-quality products. At the same time, Desheng focuses on technological innovation and research and development, continuously optimizing production processes, improving product performance, and reducing costs. If you have any relevant needs, please click on the website to inquire about details and purchase!

In the fields of biochemistry and medical diagnosis, the detection of triglycerides has always been one of the important indicators for evaluating human health status. Triglycerides are fat molecules formed by 3 molecules of long-chain fatty acids and glycerol, and are one of the most abundant lipids in the human body. They play an important role in energy supply, cell structure, and function. However, when the level of triglycerides is too high, it may increase the risk of cardiovascular disease, obesity, diabetes and other chronic diseases. Therefore, accurate measurement of triglyceride content is of great significance for evaluating human health status. In the detection of triglycerides, the chromogenic substrate TODB (the new Trinder's reagent) plays a crucial role. This article will delve into the working principle, advantages, and clinical applications of TODB in triglyceride detection. The working principle of TODB in triglyceride detection As a chromogenic substrate, TODB's core lies in its unique chemical structure. In the presence of hydrogen peroxide and peroxidase, TODB can undergo oxidative coupling reactions with specific oxidants (such as 4-aminoantipyrine) to generate stable colored compounds. The color change of this compound is directly proportional to the concentration of hydrogen peroxide, therefore, by accurately measuring its absorbance, the content of triglycerides in the blood can be indirectly calculated. In the triglyceride detection kit, the application of TODB is mainly based on the following principle: when triglycerides in the sample are oxidized and decomposed by specific enzymes, hydrogen peroxide is produced. At this point, TODB interacts with hydrogen peroxide and peroxidase to form colored compounds. By measuring the absorbance of this compound, quantitative analysis of triglycerides can be achieved. Advantages of TODB in triglyceride detection 1. High sensitivity and accuracy: TODB has high sensitivity in color reaction and can accurately capture trace changes in hydrogen peroxide, thereby achieving accurate determination of triglycerides. This high sensitivity not only improves the accuracy of detection, but also provides the possibility for early detection of blood lipid abnormalities. 2. Easy and fast operation: Using a triglyceride detection kit containing TODB for detection is relatively simple and does not require complex instruments and equipment. This greatly shortens the detection time, improves work efficiency, and makes triglyceride detection more convenient and efficient. 3. Strong stability: The color products generated by TODB are stable and not easily affected by environmental factors. This ensures the reliability and long-term effectiveness of the test results, providing strong support for clinical diagnosis and treatment. 4. Wide applicability: TODB is not only suitable for the detection of serum and plasma samples, but also for the detection of various biological samples such as cerebrospinal fluid, cells, and tissues. This further expands its application scope in biomedical research and clinical diagnosis. Clinical application of TODB in triglyceride detection 1. Cardiovascular disease risk assessment: Triglycerides are one of the important risk factors for cardiovascular disease. By accurately measuring triglyceride levels, doctors can assess a patient's cardiovascular disease risk and develop effective prevention and treatment strategies. 2. Obesity and diabetes monitoring: Obesity and diabetes are often accompanied by elevated triglyceride levels. Regular monitoring of triglyceride levels helps doctors detect changes in the condition in a timely manner, adjust treatment plans, and improve treatment outcomes. 3. Nutritional assessment and guidance: Triglyceride levels are also influenced by diet and nutritional status. By detecting triglyceride levels, personalized nutritional guidance can be provided to patients to help improve their dietary habits and reduce the risk of cardiovascular disease. 4. Evaluation of drug efficacy: Regular monitoring of triglyceride levels during drug therapy can help evaluate the efficacy and side effects of the medication. Doctors can adjust medication dosage or change treatment plans based on test results to improve treatment effectiveness. Conclusion TODB, as an efficient and sensitive colorimetric reagent, plays a crucial role in triglyceride detection. Its unique chemical structure and color development principle make triglyceride detection more accurate, convenient, and fast. Desheng specializes in producing more than ten new Trinder's reagents, including TODB. After more than ten years of research and development, it can ensure that TODB appears as a powder with a purity of up to 99.5%, strong water solubility, and stable performance to ensure the accuracy of experimental results. Desheng has a place in the market for in vitro diagnostic kit raw materials with high-quality products, and is deeply trusted and supported by customers at home and abroad. If you have any relevant intentions, please click on the official website for consultation!

From March 22nd to 24th, 2025, the Hangzhou Convention and Exhibition Center will host the annual event in the field of in vitro diagnostics - CACLP Exhibition. As an active participant in the in vitro diagnostic industry, Hubei Xindesheng Materials Co., Ltd. will showcase its research and development of new products and technologies at the exhibition, booth number: 4-A 0003. We sincerely invite you to visit our booth to discuss the future of the industry and explore opportunities for cooperation! 1, Precautions for attending exhibitions To help you better visit the exhibition, we have compiled some precautions for you: Pre registration: It is recommended that you pre register for the visit on the CACLP official website in advance to save time queuing on site. Develop a visit plan: Understand the exhibitor list and booth distribution in advance, develop a reasonable visit route, and improve visit efficiency. Carrying business cards: convenient for exchanging contact information with exhibitors and facilitating future communication and cooperation. Follow the exhibition activities: During the CACLP exhibition, multiple summit forums, technical seminars, and other events will be held. We recommend that you pay attention to and register in advance to participate. Attention to safety: During the exhibition, there will be a large flow of people. Please take good care of your personal belongings and follow the exhibition order. 2, Exhibition Guide In order to make your visit smoother, we have prepared an exhibition guide for you: Transportation Guide: Airplane: Take a plane to Hangzhou Xiaoshan International Airport, and you can take the airport bus or subway to Hangzhou Convention and Exhibition Center.High speed rail: Take the high-speed rail to Hangzhou East Station or Hangzhou Station, and you can take the subway or taxi to Hangzhou Convention and Exhibition Center. Self driving: Navigate to the "Hangzhou Grand Convention and Exhibition Center" and a parking lot will be provided during the exhibition period.Exhibition map: Familiarize yourself with the exhibition layout in advance, understand the functional distribution of each exhibition hall, in order to quickly find the target booth. 3, Highlights of Desheng booth: Core products and newly invested enzyme preparation products At this exhibition, Hubei Xindesheng Materials will showcase the following core products and newly invested enzyme preparation products: Core products: Hubei Xindesheng Materials will showcase the company's core products at booth (4-A0003). As for the blood collection tube additive series, products such as serum separation gel, heparin lithium, heparin sodium, EDTA dipotassium/tripotassium/disodium, coagulant, coagulant powder, etc. will be displayed in sequence. Biological buffering agents will display products such as TRIS, HEPES, MOPS, CAPS, TAPS, etc. Newly invested enzyme preparation products: In 2024, the company established an enzyme preparation project team. At this exhibition, the company will showcase enzyme preparation related products at the CACLP exhibition. Our technical team will explain the characteristics and applications of the products in detail on site and provide professional solutions. 4, Looking ahead to the future Hubei Xindesheng Materials has always been committed to technological innovation and product research and development in the field of in vitro diagnostics. In the future, we will continue to increase our R&D investment to meet the diverse needs of the market. At the same time, we will actively expand our international market and work together with global customers and partners to promote the development of the in vitro diagnostic industry. From March 22nd to 24th, 2025, at the Hangzhou Convention and Exhibition Center and CACLP exhibition, Hubei Xindesheng Materials will meet you at any time! We look forward to working together with you to create a better future for the in vitro diagnostic industry!

In the field of biochemical analysis, the chromogenic substrate ADOS is widely used for quantitative detection of hydrogen peroxide due to its high sensitivity, easy operation, and good stability. However, in practical applications, the color change of ADOS may be affected by various factors, which can affect the accuracy and reliability of the detection results. This article will explore in detail the factors that may affect the color change of ADOS, in order to provide reference for researchers in related fields. The influence of experimental conditions on the color change of ADOS 1. Temperature Temperature is an important factor affecting the rate and equilibrium of chemical reactions. For the oxidative coupling reaction of ADOS with hydrogen peroxide and peroxidase, temperature changes may directly affect the reaction rate and the amount of product generated, thereby affecting the intensity of color change. Generally speaking, as the temperature increases, the reaction rate accelerates and the color change may become more pronounced. However, excessively high temperatures can also lead to enzyme inactivation or substrate degradation, thereby reducing sensitivity to color changes. Therefore, it is necessary to strictly control the temperature during the experiment to ensure that it fluctuates within an appropriate range. 2. pH value PH value is a key factor affecting enzyme activity, substrate stability, and product generation. The color reaction of ADOS usually occurs within a specific pH range, and exceeding this range may result in subtle color changes or interference. For example, in environments with strong acidity or alkalinity, ADOS or enzymes may degrade or become inactive, leading to a reduction or disappearance of color changes. Therefore, it is necessary to accurately measure and adjust the pH value of the solution before the experiment to ensure that it is within the appropriate range. Interference from chemical substances 1. Metal ions Certain metal ions such as iron and copper may interfere with the color reaction of ADOS. These metal ions may act as catalysts or inhibitors to affect the progress of the reaction, thereby altering the intensity of color changes. In addition, metal ions may directly bind to ADOS or enzymes, leading to substrate or enzyme inactivation. Therefore, it is necessary to avoid using reagents or containers containing these metal ions during the experimental process to reduce interference. 2. Reducing agent Reductive agents such as vitamin C and glutathione may have reducibility, which can consume hydrogen peroxide or affect the oxidative coupling reaction of ADOS, thereby reducing the intensity of color change. Therefore, when testing samples containing these reducing agents, appropriate pre-treatment measures need to be taken, such as adding oxidants to eliminate the influence of reducing agents. 3. Strong oxidizing agent Strong oxidants such as potassium permanganate and potassium dichromate may directly oxidize ADOS or enzymes, resulting in subtle color changes or interference. Therefore, it is necessary to avoid using these strong oxidants as reagents or solvents during the experimental process. Interference from biological factors 1. Changes in enzyme activity The color reaction of ADOS depends on the activity of peroxidase. However, the activity of enzymes may be influenced by various biological factors, such as temperature, pH value, the presence of inhibitors and activators, etc. These factors may lead to changes in enzyme activity, thereby affecting the intensity of color changes. Therefore, it is necessary to strictly control these factors during the experimental process to ensure the stability of enzyme activity. 2. The complexity of the sample In practical applications, samples often have complexity and may contain multiple biomolecules and chemical substances. These substances may interfere with the color reaction of ADOS, resulting in unclear color changes or false positive or false negative results. Therefore, appropriate preprocessing measures such as centrifugation, filtration, dilution, etc. need to be taken during sample processing to reduce the impact of interfering substances. Errors during the operation process 1. Instrument error The accuracy and stability of instruments such as spectrophotometers are crucial for measuring color changes in ADOS. The error of the instrument may lead to inaccurate measurement of color change intensity, thereby affecting the reliability of the detection results. Therefore, it is necessary to calibrate and validate the instrument before the experiment to ensure that its accuracy and stability meet the requirements. 2. Operational errors Operational errors during the experimental process may also affect the measurement of ADOS color changes. For example, the amount of reagents added, control of reaction time, and uniformity of solution mixing may all affect the intensity of color change. Therefore, it is necessary to strictly follow the operating procedures during the experiment to ensure the accuracy and consistency of the operation. Conclusion In summary, the color change of the chromogenic substrate ADOS may be influenced by various factors, including experimental conditions, chemical substances, biological factors, and errors during the operation process. In order to obtain accurate and reliable detection results, it is necessary to strictly control these factors during the experimental process and take appropriate preprocessing measures and instrument calibration methods. In addition, with the continuous advancement of science and technology and the deepening expansion of applications, it is believed that there will be more new types of chromogenic substrates and detection technologies in the future, providing more accurate, sensitive, and convenient detection methods for the field of biochemical analysis. Desheng is a well-established blood testing reagent company with years of experience in research and development and production. It has gathered products including chemiluminescence reagents, biological buffering agents, color reagents, enzyme preparations, blood collection tube additives, antigen antibodies, etc. It has deep research on the new Trinder's reagent. The ADOS products produced by the company have a purity of over 99% detected by HPLC. The product packaging is standardized to ensure safe transportation and timely after-sales service, so that customers can receive satisfactory products.