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Wuhan Desheng Biochemical Technology Co., Ltd
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Wuhan Desheng Biochemical Technology Co., Ltd

Company IntroductionWuhan Desheng Biochemical Technology Co., Ltd. is founded in 2005, located in Wuhan, China, specializing in R&D, production and sales of blood collection tube additives and homology chemcial reagents.We are mainly engaged in blood specimen pretreatment reagents including anticoagulant series: lithium heparin, sodium heparin, EDTA K2/K3, blood specimen coagulant series: powder and liquid of blood clot accelerator etc; blood specimen pretreatment series: serum separating gel ...
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China Wuhan Desheng Biochemical Technology Co., Ltd

2005

Year Established

10000000 +

Annual Sales

>100 +

Employees

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Do you know how to judge the quality of serum separation gel?
2024-07-12
Judging the quality of serum separation gel is a crucial step in clinical testing and biological research, as it directly affects the efficiency of blood sample processing and the accuracy of results. Serum separation gel, as a special additive, is widely used in vacuum blood collection tubes. Its main function is to form an isolation membrane during centrifugation to separate serum from blood clots, thereby protecting serum components from contamination by cellular components and maintaining sample stability. The following is a detailed explanation of how to determine the quality of serum separation gel from multiple dimensions. 1.Thixotropic properties and viscosity The thixotropy of serum separation gel is one of its core characteristics, which determines the flow behavior of the gel under different external forces. The ideal separation gel should reduce its viscosity due to force during centrifugation, making it easier to pass through the blood cell layer and form a stable isolation layer. Once centrifugation stops, the viscosity quickly recovers, maintaining the isolation effect. Separation gel with poor thixotropy may result in poor flipping or formation of a uniform isolation layer, affecting the purity of serum. Meanwhile, viscosity is another key indicator that not only affects the smoothness of the gluing process, but also determines the flowability of the colloid during centrifugation. Excessive or insufficient viscosity can cause inconvenience to operation or affect separation efficiency. Although most manufacturers do not explicitly indicate viscosity, good separation adhesives should have suitable and stable viscosity values to ensure the convenience and effectiveness of adding adhesive. 2.Specific gravity and separation effect The specific gravity of serum separation gel is usually designed between 1.045 and 1.065g/cm ³, which ensures that the separation gel can be located between blood cells and serum after centrifugation, forming a good physical barrier. Separation gel with a specific gravity that does not meet the requirements may not be able to accurately separate layers, leading to the infiltration of blood cell components into the serum and affecting subsequent test results. In addition, for specific applications such as PRP (platelet rich plasma) collection, the specific gravity of the separation gel needs to be accurately matched to achieve finer separation.   3、 Shelf life and stability A good serum separation gel should have good long-term stability, and even under specified storage conditions (such as avoiding light, room temperature, or refrigeration), there should be no aging or solidification phenomenon. The shelf life of products from different manufacturers varies, generally ranging from one to three years. However, regardless of the duration, the key is that during this period, the thixotropy, viscosity, and specific gravity of the separation adhesive should remain unchanged. Long term stability testing is an important basis for assessing its quality, ensuring that even after prolonged use, the original characteristics of the blood sample are not compromised. 4、 Sample processing capability The key to testing the efficacy of serum separation gel is whether it can quickly form a stable isolation layer upon contact with blood, and whether it can maintain the original characteristics of the sample over a long period of time. In clinical practice, if the quality of the separation gel in the blood collection tube is poor and the specific gravity does not meet the standard, it may lead to the mixing of serum and blood cell components, and even the appearance of fibrin fibers in the serum, which usually means poor blood coagulation or improper centrifugation conditions. Therefore, a good separation gel should be able to quickly and coagulate blood, avoid contamination of serum by fibrin and other cellular components, and ensure the reliability of analysis results. 5、 Anti interference and compatibility High quality serum separation gel should also have good anti-interference ability, which means it can maintain stable separation effect under various sample conditions, without being affected by sample type, blood composition changes, or external factors such as temperature fluctuations. In addition, compatibility is also important as it should be compatible with various conventional centrifugal equipment, automated analytical instruments, and subsequent biochemical detection methods without affecting the test results.   In summary, when selecting serum separation gels, laboratories and medical institutions should comprehensively evaluate the above factors to ensure that the selected products can meet experimental requirements, improve detection efficiency and accuracy, and provide reliable data support for clinical diagnosis and scientific research. Desheng is a professional manufacturer of serum separation gel, with an independent research and development team and strict quality control by professional personnel. If you have purchasing needs, please feel free to contact us for purchase!
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Application of Bicine in the Preparation of Stable Substrate Solutions
2024-07-11
Application of Bicine in the Preparation of Stable Substrate Solutions The stability of substrate solutions is crucial for the accuracy of experimental results in biochemistry and molecular biology experiments. Among them, Bicine (N, N-di (hydroxyethyl) glycine) is highly favored as a biological buffer due to its excellent properties, playing an indispensable role in preparing stable substrate solutions. This article will discuss in detail the application of Bicine in the preparation of stable substrate solutions from multiple aspects.     The basic characteristics of Bicine Bicine, Also known as N, N-di (hydroxyethyl) glycine, it is a zwitterionic buffer and belongs to the Good's buffer series. Its CAS number is 150-25-4, and its pH buffer range is between 7.6-9.0. As a biological buffer, Bicine is widely used in low-temperature biochemical work, especially in the preparation of stable substrate solutions. Application of Bicine in the Preparation of Stable Substrate Solutions 1. Enzyme reaction buffer In enzymatic reactions, enzymes act as biocatalysts and their activity is greatly influenced by pH values. Bicine, as an enzyme reaction buffer, can maintain pH stability within a certain range, providing a suitable environment for enzymatic reactions. Meanwhile, Bicine has strong buffering ability and can resist external acid-base interference, ensuring the stability of the substrate solution. 2. Serum guanine enzyme determination In the experiment of serum guanine enzyme determination, the stability of the substrate solution is crucial for the accuracy of the measurement results. Bicine, as a biological buffer, can effectively stabilize substrate solutions and prevent them from changing during the measurement process. Meanwhile, Bicine can also interact with other components in the serum, improving the sensitivity and accuracy of the measurement. 3. Electrophoretic buffer Electrophoresis buffer is an important part of nucleic acid and protein gel electrophoresis system, which is of great significance for maintaining a constant pH value of the electrophoresis system. Bicine, as an electrophoresis buffer, can provide a stable pH environment for biological macromolecules such as nucleic acids and proteins during the electrophoresis process, ensuring their stability during the electrophoresis process. In addition, Bicine's buffering ability can also resist external acid-base interference, ensuring the accuracy of electrophoresis results. Preparation method of Bicine The preparation method of Bicine is relatively simple, usually requiring the preparation of Bicine powder and deionized water. Firstly, dissolve Bicine powder in deionized water in a certain proportion to prepare a certain concentration of Bicine solution. Then, according to experimental needs, the pH value of Bicine solution can be adjusted by adding alkaline solutions such as NaOH. It should be noted that during the preparation process, factors such as temperature, stirring speed, and mixing ratio should be strictly controlled to ensure the quality and stability of Bicine solution. conclusion In summary, Bicine plays an important role as an excellent biological buffer in the preparation of stable substrate solutions. Its pH buffering ability and stability make it an ideal choice for enzymatic reactions, serum guanine enzyme determination, and electrophoresis buffer solutions. With the continuous deepening of research in biochemistry and molecular biology, the application prospects of Bicine will be even broader. As a supplier of Bicine buffer, Desheng always adheres to the pursuit of quality and continuous exploration of innovation. Its Bicine raw materials are not only of superior quality and stable performance, but also suitable for various fields. As a customer-centric manufacturer, Desheng understands the importance of customer needs and provides a wide range of buffer products, from commonly used specifications to customization, ensuring that customers can find solutions that meet their needs here. At the same time, Desheng also provides professional technical support and after-sales service, allowing customers to enjoy a more convenient shopping experience. If you have any relevant intentions, please feel free to click on the website to inquire about details and purchase at any time!
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The application of the new Trinder's reagent TOOS in blood glucose and liver function detection
2024-07-10
With the continuous progress of biotechnology and medical technology, biochemical testing plays an increasingly important role in clinical diagnosis and treatment. Blood glucose and liver function testing, as important components of biochemical testing, have profound significance in evaluating human health status, monitoring disease progression, and guiding clinical treatment. In recent years, the new Trinder's reagent TOOS (N-ethyl-N - (2-hydroxy-3-sulfopropyl) -3-methylaniline sodium salt) has gradually demonstrated its unique advantages and application value as a new biochemical detection reagent in blood glucose and liver function detection. This article will explore in detail the application of TOOS in blood glucose and liver function detection. The basic principle of the new Trinder's reagent TOOS TOOS is an organic compound with specific chemical structures and reaction properties. In biochemical testing, TOOS is usually used as a reaction substrate to undergo specific chemical reactions with the tested substance, generating colored products. The generation amount of this colored product is directly proportional to the concentration of the tested substance, so the concentration of the tested substance can be indirectly determined by measuring the absorbance, fluorescence intensity, and other parameters of the colored product. The advantages of TOOS lie in its high sensitivity, strong specificity, simple operation, and strong anti-interference ability, making it widely used in blood glucose and liver function detection. The application of the new Trinder's reagent TOOS in blood glucose detection Blood glucose is the concentration of glucose in the blood and an important diagnostic indicator of metabolic diseases such as diabetes. Traditional blood glucose detection methods such as glucose oxidase method, although mature and stable, may be interfered with in some cases, affecting the accuracy of the results. The application of the new Trinder's reagent TOOS in blood glucose detection provides a new and more accurate method for blood glucose detection. In the TOOS method, glucose undergoes an oxidation-reduction reaction with the TOOS reagent to produce colored products. The amount of this colored product is directly proportional to the concentration of glucose, so blood glucose concentration can be accurately measured by measuring parameters such as the absorbance of the colored product. Compared with traditional glucose oxidase methods, TOOS method has higher sensitivity and specificity, and can more accurately reflect blood glucose levels. In addition, the TOOS method has the advantages of simple operation, fast reaction speed, and strong anti-interference ability, making blood glucose detection more rapid, accurate, and reliable.   The application of the new Trinder's reagent TOOS in liver function detection Liver function testing is an important means of evaluating liver function status, including multiple indicators such as transaminase, bilirubin, albumin, etc. The new Trinder's reagent TOOS has also played an important role in liver function testing. In transaminase detection, TOOS can act as a substrate to react with transaminases and generate colored products. By measuring the absorbance and other parameters of colored products, the activity of transaminases can be indirectly measured, thereby evaluating the metabolic function of the liver. Compared with traditional colorimetric methods, the TOOS method has higher sensitivity and specificity, and can more accurately reflect changes in transaminase activity. In addition, TOOS can also be used for the detection of indicators such as bilirubin and albumin. Bilirubin is one of the important indicators of liver function, and its concentration changes can reflect the excretion function of the liver. In bilirubin detection, TOOS can react with bilirubin to generate colored products, thereby indirectly determining the concentration of bilirubin. Albumin is an important protein synthesized by the liver, and changes in its concentration can reflect the synthesis function of the liver. In albumin detection, TOOS can react with albumin as a substrate to generate colored products. By measuring the absorbance and other parameters of the colored products, the concentration of albumin can be indirectly measured. The application advantages of the new Trinder's reagent TOOS 1. High sensitivity and specificity: TOOS can react specifically with the tested substance, generate colored products, and accurately determine the concentration of the tested substance, thereby improving the sensitivity and specificity of detection. 2. Easy to operate: TOOS has simple and practical operation steps, without the need for complex instruments and cumbersome operation processes, reducing the difficulty and cost of detection. 3. Fast reaction speed: TOOS has a fast reaction speed and can complete detection in a short time, improving detection efficiency. 4. Strong anti-interference ability: TOOS has strong anti-interference ability, which can reduce the influence of external factors on the detection results and ensure the accuracy of the detection results. The new Trinder's reagent TOOS has demonstrated its unique advantages and application value in blood glucose and liver function detection. Its high sensitivity, specificity, simplicity, fast reaction speed, and strong anti-interference ability have made the TOOS method widely used in the field of biochemical detection. With the continuous progress of medical technology and the continuous innovation of biochemical detection methods, the new Trinder's reagent TOOS is expected to play a greater role in the future, providing more accurate, fast, and convenient detection methods for clinical diagnosis and treatment. Desheng is a manufacturer of new Trinder's reagents and can provide a series of reagents such as TOOS. Independently developed and produced, with small inter batch differences and sensitive reactions, it has important value in clinical diagnosis. If you need to make a purchase, please feel free to contact us for consultation and ordering!
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Exploration of the Reasons for Fading of MAOS Display Reagents
2024-07-08
In the field of chemical analysis and diagnostic testing, colorimetric reagents play a crucial role. Among them, MAOS, as a new type of Trinder's reagent, has received widespread attention due to its high water solubility and color performance. However, MAOS reagents often exhibit fading during use, which not only affects the accuracy of testing but also brings many inconveniences to experimental operations. This article will delve into the reasons why MAOS reagents are prone to fading from multiple perspectives.   1、 Chemical properties of MAOS reagents The full name of MAOS is N-ethyl-N - (2-hydroxy-3-sulfopropyl) -3,5-dimethylaniline sodium salt, which is a derivative of highly water-soluble aniline sodium salt. These substances will produce red or yellow substances after oxidation, thereby achieving color rendering function. However, the chemical properties of MAOS reagents also determine their tendency to fade. Due to the presence of easily oxidizable groups in MAOS molecules, oxidation reactions can occur when exposed to oxygen or other oxidants in the air, leading to a gradual fading of color. So when using MAOS, it is important to detect it in a timely manner and not interrupt the process. 2、 The impact of storage environment The storage environment of MAOS reagents has a significant impact on their stability. Firstly, temperature is a key factor affecting the stability of reagents. Excessive temperature can accelerate the oxidation reaction of MAOS molecules, leading to reagent discoloration. Therefore, when storing MAOS reagents, they should be placed in a cool and dry environment to ensure that the reagents are not affected by the external environment during storage. In addition, humidity is also an important factor affecting the stability of reagents. Excessive humidity can cause reagents to absorb moisture and clump, reduce their effectiveness, and even accelerate oxidation reactions. Therefore, when storing MAOS reagents, the environment should be kept dry to avoid high humidity. 3、 Precautions during operation In addition to the storage environment, precautions during operation also have a significant impact on the stability of MAOS reagents. Firstly, when preparing the MAOS reagent solution, it is necessary to strictly follow the instructions and configure the appropriate concentration. Excessive concentration may accelerate the oxidation rate of the reagent, while low concentration may affect the color rendering effect. Secondly, when using MAOS reagents, the operating environment should be kept clean and tidy to reduce the interference of impurities and pollutants. At the same time, it is advisable to avoid mixing test reagents with other chemical substances to avoid chemical reactions that may affect the detection results. Finally, the stability of MAOS reagents after opening is also a concern. Once the reagent is opened, its stability may be affected by factors such as oxygen and moisture in the air, so it should be used up as soon as possible after opening. If long-term storage is required, it should be resealed and placed in an appropriate storage environment. In summary, the main reasons for the easy fading of MAOS reagents include their chemical properties, storage environment, precautions during operation, and the lack of effective stability improvement methods. To solve this problem, we need to start from multiple aspects, optimize the storage environment, improve packaging materials, pay attention to operational details, and explore effective methods to improve stability. Only in this way can the accuracy and reliability of MAOS reagents be ensured in chemical analysis and diagnostic testing. The MAOS manufactured by Desheng is highly praised for its purity, water solubility, highly sensitive color rendering ability, and manufacturing process. The product ensures a pure white crystalline powder appearance, which is loved and recognized by users both domestically and internationally. If you are looking for a new type of The New Trinder's reagent, we sincerely invite you to visit the official website of Desheng for more detailed information.
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What Did They Say
Tony
Tony
As a distributor of hospital agent , your Blood Collection Tube Additives is very suit for my needs , i think we have establish a good business with each other , thank you !
As a distributor of hospital agent , your Blood Collection Tube Additives is very suit for my needs , i think we have establish a good business with each other , thank you !
William
William
Received the sample order and passed the test. Thank you for all your efforts. You are a reliable partner! We will continue to cooperate with you in the future.
Received the sample order and passed the test. Thank you for all your efforts. You are a reliable partner! We will continue to cooperate with you in the future.
Marinel
Marinel
The biological buffer produced by Desheng Company has high purity, good water solubility, and a white powder appearance. The price is affordable, and the after-sales service is very enthusiastic, helping us to use the biological buffer correctly and efficiently. It was a very good experience, looking forward to the next collaboration!
The biological buffer produced by Desheng Company has high purity, good water solubility, and a white powder appearance. The price is affordable, and the after-sales service is very enthusiastic, helping us to use the biological buffer correctly and efficiently. It was a very good experience, looking forward to the next collaboration!
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