China Wuhan Desheng Biochemical Technology Co., Ltd Company News

In molecular biology experiments, DNA precipitation and extraction are fundamental steps in gene research, cloning technology, and diagnostic reagent development. During this process, the selection of biological buffering agents directly affects the purity, integrity, and experimental efficiency of DNA. Trimethylmethylaminoethanesulfonic acid (TES buffer), as an efficient buffering agent, has demonstrated significant advantages in the field of DNA manipulation due to its unique physicochemical properties and stability. The chemical properties of TES: the scientific basis for buffering capacity TES, The chemical name is 2- [(trihydroxymethyl) methylamino] -1-ethanesulfonic acid, and the sulfonic acid groups and multiple hydroxyl groups in its molecular structure endow it with excellent buffering ability. At room temperature, the pKa value of TES is 7.5, and the effective buffering range covers pH 6.8-8.2, which precisely matches the activity and DNA stability requirements of most biological enzymes. Compared to traditional buffer Tris (buffer range pH 7.0-9.0), TES exhibits stronger resistance to temperature changes and can effectively avoid the risk of low-temperature induced DNA degradation. Triple core role in DNA extraction 1. Cell lysis and protein removal During the cell lysis stage, TES inhibits the activity of DNA enzymes and protects genomic DNA from degradation by chelating divalent metal ions (such as Mg ² ⁺, Ca ² ⁺) in the solution. Its buffer system simultaneously maintains the optimal pH for proteases such as proteinase K (usually pH 7.5-8.0), accelerating the breakdown of cell membranes and protein degradation. Experiments have shown that the protein removal efficiency of the lysis system using TES buffer is improved by about 25% compared to traditional methods, laying a good foundation for subsequent purification steps. 2. Selective regulation of DNA precipitation TES is a composite buffer solution composed of Tris hydrochloric acid, EDTA, and SDS (TES-EDTA-SDS), which achieves selective precipitation of DNA by adjusting the ionic strength of the solution. At high salt concentrations (such as 2.5M NaCl), the sulfonic acid groups of TES act through electrostatic shielding, promoting the repulsion of phosphate groups between DNA molecules and forming a soluble state; When the salt concentration drops below 0.5M, DNA aggregates and precipitates due to exposure of the phosphate backbone. This process has a repulsive effect on RNA and other impurities, resulting in DNA recovery purity of over 95%. 3. Enzyme activity protection The protective effect of TES buffer on enzyme activity is particularly prominent in limiting enzyme cleavage reactions. Research has shown that the cutting efficiency of restriction enzymes (such as EcoRI) using TES reaction system is 18% -22% higher than that of HEPES buffer. Its stable pH environment reduces enzyme conformational changes, prolongs the linear period of enzyme cleavage reactions, and ensures the accuracy of gene editing experiments. Conclusion TES buffer exhibits irreplaceable advantages in DNA precipitation and extraction due to its excellent pH stability, metal ion chelation properties, and enzyme protection effect. By optimizing experimental conditions and exploring new application scenarios, TES will continue to drive molecular biology research towards more efficient and precise directions. For researchers, mastering the buffering mechanism and application techniques of TES is undoubtedly the key to improving the success rate of experiments. TES buffer is not only used in cosmetics. Its buffering properties make it play an important role in protein analysis, enzyme activity determination, and cell culture. As an advantageous supplier of TES buffer, Desheng can provide high-purity and diverse types of buffer raw materials. Customers can complete one-stop procurement, saving time and costs. If you have any relevant intentions, please feel free to contact us for purchase at any time!

In molecular biology experiments, electrophoresis analysis is the core technology for separating and identifying biomolecules such as nucleic acids and proteins. The choice of buffer directly affects the accuracy and reliability of experimental results, and MOPS (3- (N-morpholino) propanesulfonic acid) buffer exhibits significant advantages in electrophoretic analysis due to its unique chemical properties and stability. Chemical properties and buffering mechanism of MOPS MOPS is an organic compound containing sulfonic acid groups and a morpholine ring, with a pKa value of 7.2 and an effective buffering range of pH 6.5-7.9. This range is close to the physiological pH value, which gives MOPS a natural advantage in simulating the biological environment in research. The buffering mechanism of MOPS maintains solution stability over a wide pH range through protonation and deprotonation reactions. Its moderate ion strength ensures both electric field uniformity and reduces non-specific interactions, providing an ideal migration environment for biomolecules. The core advantages of MOPS in electrophoretic analysis 1. Protect the MOPS buffer solution of biomolecules to maintain a stable pH environment during electrophoresis, effectively preventing degradation or denaturation of RNA and proteins due to acid-base changes. Compared with traditional buffering agents, MOPS can significantly reduce the hydrolysis reaction of nucleic acids and maintain the natural conformation of proteins. Experiments have shown that RNA electrophoresis using MOPS buffer improves band clarity by about 30% compared to TAE buffer. 2. Improve the separation efficiency. The weak alkaline properties (pH 7.0-7.5) of MOPS provide uniform charge distribution for biomolecules and promote their effective migration in an electric field. In protein electrophoresis, the low viscosity property of MOPS reduces sample diffusion by about 25% and significantly improves resolution. Compared with TBE buffer, MOPS exhibits higher peak symmetry when separating proteins smaller than 15kDa. 3. Multi scene compatibility MOPS buffer is compatible with agarose gel, polyacrylamide gel and other electrophoresis systems. In Northern hybridization, MOPS as a transmembrane buffer can reduce non-specific binding of RNA to the membrane and improve hybridization efficiency. Its non fluorescent interference characteristic gives it an advantage in fluorescence labeled electrophoresis. Comparison between MOPS and other buffering agents 1. TAE buffer: TAE has weak buffering capacity, but is easy to prepare and cost-effective, suitable for electrophoretic analysis of large molecular DNA fragments. 2. TBE buffer: It has high buffering capacity and is suitable for the separation of small molecule DNA fragments, but it may lead to RNA degradation in RNA electrophoresis. Conclusion MOPS buffer is becoming an important tool in the field of electrophoretic analysis due to its unique advantages. With the deepening of research, MOPS will play a key role in more fields and promote the innovative development of biotechnology. Whether in basic research or industrial applications, MOPS is known for its stable performance and outstanding performance. Whether in protein purification, electrophoresis, or cell culture, MOPS can provide reliable pH stability, helping researchers obtain accurate and reproducible experimental results. Desheng is a professional manufacturer of biological buffering agents, established for more than ten years. It has rich experience in research and development, production, and product knowledge, and can provide customers with a large amount of technical support and after-sales guarantee. The biological buffer products currently produced include MOPS, TRIS, HEPES, TAPS, CAPS, BICINE, EPPS, PEP and a series of other biological buffer solutions. If you need them, please feel free to contact us at any time!

In today's rapidly developing global medical testing technology, chemiluminescence reagents, as "precise probes" in the field of in vitro diagnostics (IVD), are writing a differentiated market landscape with changes in economic and medical needs in different regions. From the vibrant vitality of emerging markets in Asia to the stable landscape of mature markets in Europe and America, the competition and opportunities in this blue ocean reflect profound changes in the global healthcare industry. 1, Asia: Accelerating the Start of Growth Engines On this vibrant land of Asia, the chemiluminescence reagent market is reshaping the industry landscape at an astonishing speed. When the skyscrapers in Lujiazui, Shanghai and the technology park in Bangalore, India shine together, it is the awakening of health awareness among hundreds of millions of people. The wave of urbanization has not only changed the skyline, but also promoted the upgrading of primary healthcare facilities - from tertiary hospitals to community clinics, the popularization of detection equipment has enabled chemiluminescence technology to reach a wider range of people. China and India, as dual drivers of regional development, demonstrate a unique development logic. In the medical device industry park in Shenzhen, the chemiluminescence detection system developed by local enterprises has been able to achieve "same day sampling, same day results", and this efficiency innovation is radiating from big cities to county-level medical centers. The graded diagnosis and treatment policy implemented by the government is like a conveyor belt, delivering advanced testing technology to every corner that needs it. The thriving private healthcare system in India has created a unique development model by combining the introduction of international equipment with localized reagents. It is worth noting that innovative forces are rising on this land. A biotechnology company located in Suzhou has reduced testing costs by 30% by improving reagent formulations, enabling remote health centers to conduct thyroid function screening. This down-to-earth technological innovation is a vivid footnote to the vitality of the Asian market. 2, Europe and America: Maintaining Integrity in Mature Markets and Emerging Innovation The European and American markets spanning the Atlantic exhibit different developmental rhythms. At the medical exhibition in Munich, Germany, the century old brand's chemiluminescence instrument still occupies the C position, but the most discussed topic in front of the booth is no longer simply parameter competition, but how to extend the equipment's life cycle through intelligent transformation. This transformation reveals the survival philosophy of mature markets: mining service value in stock competition. The strict healthcare regulatory system in Europe is like a double-edged sword. It not only ensures the stability of testing quality, but also makes the admission of new products like crossing layers of checkpoints. But wise practitioners have found a way to break through - an Italian company has combined a chemiluminescence platform with blockchain technology to create a fully traceable detection system that meets regulatory requirements and creates new service premiums. The arena of the North American market is filled with "songs of ice and fire". In the biotechnology cluster area of Boston, startups are attempting to disrupt traditional testing models with miniaturized devices, while established giants are consolidating their moats by acquiring innovative reagent companies. This continuous technological iteration ensures that even in the context of slowing market growth, the spark of innovation continues to thrive. 3, Future vision: Technology accessibility and value reconstruction From a global perspective, the regional differences in the chemiluminescence reagent market are essentially a mirror reflection of the uneven distribution of medical resources. While the Asian market is still addressing the question of 'whether or not', the European and American markets are already exploring higher pursuits of 'whether or not'. This development gap precisely provides space for technology transfer and model innovation. It is worth looking forward to that the digital wave is blurring geographical boundaries. A cloud based quality control system developed by a Singaporean company can provide real-time data support for both community hospitals in Bangkok and private clinics in Chicago. This technology sharing that transcends geographical limitations may reshape the rules of competition in the future. Under the wave of silver hair in an aging society, the demand for testing has grown beyond geographical limitations. The Alzheimer's disease early screening kit developed in Japan has been widely used in elderly physical examinations in the Yangtze River Delta region after localization and improvement by Chinese companies; The tumor marker detection scheme developed by Germany has also been produced in India through technology authorization. This global collaborative innovation ecosystem is writing a new narrative for industry development.

Industry opportunities under the global economic development trend Against the backdrop of a "K-shaped recovery" in the global economy, the in vitro diagnostic industry is facing opportunities for differentiated development. In 2023, the global medical device market size will exceed $580 billion, with the in vitro diagnostic sector continuing to increase to 13.2%. As the largest individual market, the export value of IVD products in the United States increased by 8.7% year-on-year, while the European Union's market concentration has significantly increased after the implementation of the In Vitro Diagnostic Medical Device Regulation (IVDR), with the top ten companies having a market share exceeding 65%. As the world's second-largest medical market, China's in vitro diagnostic market is expected to reach 125.8 billion yuan in 2023. With a stable GDP growth rate of around 5% in the new normal of the economy, the industry is exhibiting countercyclical growth characteristics. It is worth noting that the export volume of diagnostic reagents exceeded 30 billion yuan for the first time, among which the contribution rate of countries along the "the Belt and Road" increased to 37%, marking a new stage in the global layout of the industry. The market transformation brought about by economic structural adjustment Driven by the development pattern of "dual circulation", the domestic in vitro diagnostic market presents three major structural changes: 1. Consumer upgrading drives an increase in the proportion of high-end products, with an annual increase of 25% in the installed capacity of chemiluminescence detection equipment. The number of single machine detection projects in tertiary hospitals has exceeded 150 2. The rapid rise of the county-level medical market has led to a 41% year-on-year increase in the purchase of POCT equipment by primary healthcare institutions in 2023 3. The innovation of service models is accelerating, and the revenue growth rate of third-party medical testing services has reached 34%, significantly higher than the sales growth rate of traditional products Of particular note is the surge in demand for products that combine cost-effectiveness and diagnostic accuracy among medical institutions in the context of healthcare payment reform (DRGs/DIP). In 2023, the daily average detection volume of a single fully automatic biochemical analyzer in China exceeded 2000 tests, which is three times higher than five years ago, confirming the trend of equipment upgrading driven by operational efficiency. The dual empowerment effect of policy environment The coordinated efforts of regulatory policies and industrial policies are reshaping the competitive landscape of the industry. After the implementation of the new version of the "Classification Catalogue of Medical Devices" in 2023, the average registration period for Class II IVD products will be shortened to 14 months, and the utilization rate of the special approval channel for innovative products will increase by 60%. The "14th Five Year Plan" for the development of the medical equipment industry clearly proposes five major technological directions for key development, including microfluidic chips and single-molecule detection. Under policy guidance, the R&D investment intensity in related fields has reached 12.8%. At the level of quality supervision, the frequency of flight inspections conducted by the National Medical Products Administration has increased by 45% year-on-year, and the failure rate of flight inspections has decreased from 17% in 2019 to 6% in 2023, significantly improving the standardization level of the industry. It is worth noting that the IVD reagent UDI (Unique Identification) full process traceability system launched in 2024 will drive the industry into a new stage of digital supervision. Resonance between Capital Market and Industrial Innovation Under the background of deepening the registration system reform, the IPO financing in the IVD field reached 21.8 billion yuan in 2023, setting a new historical high. The average R&D investment of the 15 IVD companies listed on the Science and Technology Innovation Board accounts for 19%, significantly higher than the industry average. The strong support of the capital market drives enterprises to accelerate their layout: 1. In the field of molecular diagnostics, the localization rate of digital PCR equipment has exceeded 40% 2. Mass spectrometry detection field: Domestic enterprises have obtained 25 clinical mass spectrometry reagent registration certificates 3. Smart Laboratory: LIS system penetration rate increases to 78%, AI assisted diagnostic module installation increases by 150% annually Under the dual drive of policies and capital, the industry is forming a virtuous cycle of "innovative research and development clinical validation industrialization". In 2023, the number of PCT patent applications in the IVD field in China will reach 1562, with a year-on-year increase of 28%, of which technological breakthroughs in subdivisions such as infectious diseases detection and early screening of tumors will be particularly significant. Hubei Xindesheng Material Technology, as a well-established enterprise in IVD core raw materials, helps domestic molecular diagnostic equipment shorten the technological gap with imported products. Through the dual wheel drive of "raw materials+algorithms", Xindesheng is providing the industry with a bottom-up technology solution that combines cost advantages and quality breakthroughs.  

Population structure changes give rise to rigid demand The elderly population aged 60 and above in China has exceeded 280 million, and the per capita medical expenditure of this group is 3.2 times that of young adults, directly promoting the expansion of the chronic disease testing market at a compound annual growth rate of 18%. In the field of diabetes management, the market scale of blood glucose monitoring products reached 9.5 billion yuan, and the market penetration rate of CGMS rapidly increased from 5% in 2020 to 17% in 2023. The adjustment of the birth policy brings structural opportunities. In 2023, the sales of prenatal screening reagents increased by 31% year-on-year, and the genetic disease testing projects for newborns have covered more than 200 diseases. It is worth noting that the tumor early screening market has shown explosive growth, with sales of 800 million yuan in the first year of the launch of multi cancer joint detection products based on NGS technology. Upgrading health consumption drives market segmentation The per capita healthcare expenditure of residents has increased to 8.7% of consumption expenditure, giving rise to three major consumption trends: 1. Precise testing demand: The number of users for personalized drug genetic testing services has exceeded 5 million 2. Convenience demand: the annual growth rate of the household self-test product market reached 45%, and the COVID-19 antigen test continued to increase after normalization 3. Preventive testing: The penetration rate of cancer early screening products in the 35-50 age group has increased to 12% The upgrading of consumption is also reflected in the improvement of testing quality requirements. Third level hospitals require a coverage rate of 92% for the traceability ability of testing items, and as a result, the market size of quality control products maintains an annual growth rate of over 20%. In terms of payment ability, the number of testing projects covered by commercial health insurance has increased from 87 in 2019 to 215 in 2023, significantly expanding the high-end testing market space. Structural opportunities brought by healthcare system reform After the deepening implementation of the hierarchical diagnosis and treatment system, the number of testing projects carried out in primary medical institutions will increase by 38% year-on-year in 2023, promoting the continuous expansion of the POCT equipment market. The construction of medical consortia has led to the rise of regional testing centers, with 70% of county-level medical consortia achieving mutual recognition of testing results, driving the sinking of high-throughput testing equipment into the market. The DRG payment reform has forced medical institutions to optimize their testing processes. By 2023, the average testing turnover time (TAT) of tertiary hospitals will be reduced to 2.1 hours, an increase of 40% in efficiency compared to before the reform. This transformation directly stimulates the demand for automated assembly lines, with an annual increase of 65% in the installed capacity of laboratory automation systems (LAS) in China, and the maximum number of connected modules in a single laboratory reaching 12. Innovation in the Mode of Third Party Inspection Services The market concentration of ICL (Independent Medical Laboratory) continues to increase, with the top three companies accounting for 68% of the market share. There are three major development trends in the industry in 2023: 1. The proportion of special testing services has increased to 35%, with tumor gene testing and rare disease diagnosis becoming growth engines 2. Digital service upgrade, 88% of ICLs achieve mobile report query and intelligent interpretation 3. Extension of the industrial chain, leading enterprises begin to lay out accompanying diagnostic centers and precision treatment alliances Breakthroughs have been made in the construction of regional testing centers, with an average daily testing volume of over 100000 items in 23 provincial-level regional testing centers. The economies of scale have reduced the cost of single testing by 28%. In the field of emergency detection, the establishment of a pathogen monitoring network in 78 cities has shortened the response time for detecting new infectious diseases to 48 hours. Deep integration of technological innovation and clinical needs The clinical demand-oriented research and development model has achieved significant results: In the field of severe illness, the detection time of early diagnostic indicators for sepsis is advanced to 4 hours after the onset of symptoms Chronic disease management: the dynamic monitoring system based on wearable devices increased the compliance rate of diabetes control by 25% Tumor diagnosis and treatment: MRD (minimal residual lesion) detection technology achieves a recurrence monitoring sensitivity of 0.01% The collaborative innovation mechanism between medical institutions and enterprises is gradually improving. In 2023, 27 "Medical Engineering Cross Union Laboratories" will be established to promote the clinical translation of 15 innovative testing technologies. In terms of standard construction, the latest 23 industry standards, including the "Expert Consensus on Clinical Application of Liquid Chromatography Mass Spectrometry," have paved the way for the application of new technologies. Hubei Xindesheng Material Technology has built a comprehensive solution covering the entire diagnostic process, focusing on core products such as blood collection tube additives, biological buffering agents, and chromogenic substrates. Assist medical institutions in addressing the challenges of DRG payment reform. By continuously providing cost-effective raw material products, enterprises are becoming a solid support for the development of inclusive healthcare.

In the chemical industry, anionic surfactants are an important class of compounds with wide applications. They not only have excellent wetting, dispersing, emulsifying, foaming, and washing properties, but also play a key role in fields such as medicine, pesticides, textiles, cosmetics, and food industry. As a multifunctional compound, the biological buffer CAPSO buffer (3- (cyclohexylamine) -2-hydroxy-1-propanesulfonic acid) exhibits unique advantages in the preparation of anionic surfactants due to its unique chemical structure and properties. Basic properties of CAPSO CAPSO is a white powdery substance with good water solubility. The molecular structure of CAPSO contains both hydrophilic sulfonate groups and highly active hydroxyl groups, which makes it easy for CAPSO to undergo reactions such as detachment and substitution, thus endowing it with diversity as a functional substance. The advantages of CAPSO in preparing anionic surfactants 1. Environmental friendliness: CAPSO, as a biological buffering agent, is usually prepared using environmentally friendly raw materials and has mild reaction conditions, reducing the emission of harmful substances. 2. Efficiency: The active hydroxyl and sulfonate groups of CAPSO endow it with excellent reactivity, enabling the reaction to be completed in a relatively short time and improving production efficiency. 3. Multifunctionality: By adjusting the structure and reaction conditions of CAPSO, anionic surfactants with different properties and applications can be prepared to meet various application needs. 4. Biocompatibility: CAPSO, as a biological buffering agent, usually produces anionic surfactants with good biocompatibility, which are suitable for fields such as medicine, cosmetics, and food industry. Application examples The anionic surfactants prepared by CAPSO have shown broad application prospects in multiple fields. For example, in the detergent industry, alkyl sulfonate surfactants prepared by CAPSO have excellent washing performance and biodegradability, becoming an important component of environmentally friendly detergents. In the pesticide industry, anionic surfactants prepared by CAPSO can serve as synergists for pesticides, improving their adhesion and permeability, thereby enhancing their insecticidal efficacy and utilization rate. In the cosmetics industry, anionic surfactants prepared by CAPSO can be used as emulsifiers, dispersants, and stabilizers for the preparation of various cosmetic formulations. Conclusion In summary, the biological buffer CAPSO has unique application advantages and broad application prospects in the preparation process of anionic surfactants. By fully utilizing the chemical structure and properties of CAPSO, anionic surfactants with excellent performance and environmental characteristics can be prepared to meet various industrial application needs. In the future, with the deepening of the concepts of green chemistry and sustainable development, the application of CAPSO in the preparation of anionic surfactants will be further expanded and deepened. Desheng Biochemical is a professional manufacturer of CAPSO, with a series of products such as biological buffering agents available for everyone to choose from, as well as blood collection tube additives, luminescent reagents, and new Trinder's reagent series products. We have been developing and producing for 20 years now, with rich experience, skilled team, and guaranteed product quality. We will never let customers take the wrong path or waste money. And as a manufacturer direct sales, Desheng has a complete pre-sales and after-sales service, even if there are problems with the goods, we can solve them for you as soon as possible. If you have such needs, please click on the official website or call for consultation!

From April 24 to 26, 2025, the 32nd Türkiye Eurasia International Medical Exhibition EXPOMED EURASIA was successfully concluded in Istanbul T ü yap Exhibition Center. This medical industry event, which gathers over 1000 exhibitors and more than 35000 professional visitors, has become an important stage for Hubei Xindesheng Material Technology Co., Ltd. to showcase its strength, deepen cooperation, and look forward to the future. At this exhibition, Xindesheng showcased its full range of products and engaged in in-depth communication and cooperation with customers, leaving behind many exciting moments. The full range of products made a stunning debut, showcasing technical strength At the exhibition site, the full range of IVD reagent raw materials were neatly displayed in the booth (829C5) of Hubei Xindesheng Material Technology Co., Ltd., attracting the attention of many exhibitors. 1. The chemiluminescence series products are undoubtedly one of the focuses. Acridine ester, as a core raw material, has become a focus of attention for many customers due to its high purity and stable luminescence efficiency. Professional personnel explained in detail the mechanism of action of acridine ester in chemiluminescence immunoassay, as well as its application advantages in areas such as cancer biomarker detection and infectious disease diagnosis. From the synthesis process of raw materials to actual testing results, the multi angle display provides visitors with a visual and in-depth understanding of their performance. 2. The biological buffer series products have also attracted much attention. Tris, HEPES, Bicine and other buffering agents are arranged in an orderly manner, with detailed parameter explanations and application cases attached to each product. 3. The chromogenic substrate series products also shine brightly. TOOS, MAOS and other chromogenic substrates have become highlights at the exhibition due to their fast color development speed and low background values. In addition, the customized services provided by New Desheng to meet customer needs have also sparked a strong interest in personalized cooperation among many customers. Deep communication promotes cooperation and collaborates to explore new markets together During the exhibition, the booth of New Desheng maintained a warm atmosphere of communication. Customers from all over the world come in an endless stream, and the New Desheng team has engaged in in-depth communication and exchange with them with a professional attitude and enthusiastic service. In the face of various questions and demands raised by customers, the personnel of Xindesheng have provided detailed and professional answers. During the business negotiation phase, Xindesheng reached preliminary cooperation intentions with numerous clients and reached consensus on cooperation models, product specifications, and other aspects, preliminarily determining the cooperation framework. Through these exchanges and collaborations, Xindesheng not only expanded its market channels, but also gained a deeper understanding of the demand characteristics of customers in different regions, providing strong basis for subsequent product optimization and market layout. The exhibition has come to an end and started a new journey, forging ahead and composing a new chapter With the successful conclusion of Türkiye Medical Exhibition, Hubei Xindesheng Company has gained a lot. This exhibition not only enhanced the brand awareness of New Desheng, but also opened up a new situation for enterprises in overseas markets. The large amount of customer feedback and market demand information collected during the exhibition will become an important direction for the company's future product research and technological innovation. Since its establishment in 2005, Xindesheng has always focused on the field of IVD reagent raw materials. With modern production bases, professional R&D teams, and a sound quality control system, it continuously provides reliable quality products and services to the market. In the future, Xindesheng will take this exhibition as a new starting point, continuously strengthen technological innovation, optimize product performance, and improve service quality. Further deepen cooperation with customers at home and abroad, actively expand the market, and strive to contribute more to the development of the IVD diagnostic reagent raw material industry.

In today's rapidly advancing agricultural technology, plant hydroponics technology, as an efficient and environmentally friendly planting method, is gradually receiving widespread attention and application. Hydroponic technology provides necessary nutrients for plants by precisely controlling their growth environment, thereby achieving rapid and healthy growth. In this technological system, the selection of biological buffering agents is particularly crucial, and MOPS buffer (3-methylpropanesulfonic acid), as an excellent buffering agent, has demonstrated unique advantages in plant hydroponics. 1, MOPS: Master of acid-base balance in plant hydroponics The growth of plants has strict requirements for the pH value of the environment. In hydroponic systems, the pH value of the culture medium constantly changes due to the growth metabolism and nutrient consumption of plants. If the pH value deviates from the suitable growth range of plants, it will seriously affect the absorption and utilization of nutrients by plants, thereby affecting the growth rate and health status of plants. MOPS, as an efficient acid-base buffering agent, can provide stable buffering capacity over a wide pH range (usually 6.5-7.9), effectively neutralizing acid-base substances in the culture medium and maintaining pH stability. This stable acid-base environment provides a solid guarantee for the growth of plants, enabling them to carry out photosynthesis, nutrient absorption, and growth and development at their optimal state. 2, Multifunctionality: Comprehensive support from root fixation to nutrient supply The application of MOPS in plant hydroponics is not limited to acid-base balance, and its versatility is also one of the reasons why it is highly favored. Firstly, MOPS can serve as a fixative for plant roots, effectively fixing the roots through its viscous texture and suitable concentration, preventing them from floating or entangling in the culture medium, and improving the stability and absorption efficiency of the roots. Secondly, MOPS can also be used as a part of nutrient solutions to provide necessary nutrients for plants. Although MOPS itself does not directly provide major nutrients such as nitrogen, phosphorus, and potassium, it can form a complete nutrient solution system together with other nutrients, providing comprehensive nutritional support for plants. In addition, MOPS can also be used as a washing buffer to clean impurities and harmful substances on the surface of plant roots, keeping the roots clean and healthy. 3, Chemical stability: key to ensuring safe plant growth In plant hydroponics, chemical stability is one of the important indicators for measuring the performance of buffering agents. MOPS has excellent chemical stability and is not prone to chemical reactions with other components in the culture medium, thereby avoiding the generation of harmful substances and potential damage to plants. This chemical stability enables MOPS to maintain its buffering performance and nutrient stability in complex hydroponic environments, providing sustained and reliable support for plant growth. At the same time, MOPS does not form complexes with common metal ions such as copper, nickel, manganese, zinc, etc., avoiding the risk of toxicity to plants caused by high concentrations of metal ions. 4, Efficient dissolution and utilization: the key to improving the efficiency of nutrient solutions MOPS has good water solubility and can quickly dissolve and evenly disperse in water, forming a clear and transparent solution. This efficient solubility allows MOPS to mix evenly with other components in the hydroponic solution, improving the utilization rate of nutrient solution and the absorption efficiency of plant nutrients. This efficient dissolution and utilization characteristic enables MOPS to exert maximum efficiency in plant hydroponics, providing sufficient nutritional support for plant growth. In summary, the biological buffer MOPS has demonstrated unique advantages in plant hydroponics. Its stable acid-base balance ability, multifunctionality, chemical stability, efficient dissolution and utilization, as well as environmental protection and sustainability, make MOPS an indispensable and important component in plant hydroponic technology. With the continuous advancement of agricultural technology and the increasing demand for green and healthy agricultural products, the application prospects of MOPS in plant hydroponics will be even broader. Desheng is a professional manufacturer of biological buffering agents, established for more than ten years. It has rich experience in research and development, production, and product knowledge, and can provide customers with a large amount of technical support and after-sales guarantee. The biological buffer products currently produced include MOPS, TRIS, HEPES, TAPS, CAPS, BICINE, EPPS, PEP and a series of other biological buffer solutions. If you need them, please feel free to contact us at any time!  

In biochemical and molecular biology experiments, the ionic strength of a solution is a crucial parameter that directly affects the stability, activity, and interactions of biomolecules. In order to maintain stable experimental conditions, scientists often rely on biological buffering agents to adjust the pH and ionic strength of the solution. Among them, N, N-bis (2-hydroxyethyl) -2-aminoethanesulfonic acid (BES), as an efficient biological buffer, plays a crucial role in this field due to its excellent buffering capacity and stability. Basic properties and applications of BES BES, It is a white crystalline powder that exists stably at room temperature and pressure. As an ideal biological buffer, it is suitable for various biochemical experiments and pharmaceutical synthesis processes. BES has a wide range of applications, including but not limited to cell culture, enzymatic reactions, protein crystallization, drug development, biosensors, and chromatographic technology. During the cell culture process, BES can stabilize the pH value of the culture medium, providing a more suitable growth environment for cells, thereby improving their survival rate and proliferation efficiency. In enzymatic reactions, the buffering effect of BES can maintain the pH stability of the reaction system, ensuring that the enzyme functions at its optimal activity state and improving the efficiency and accuracy of enzymatic reactions. In addition, BES has also demonstrated its unique application value in fields such as protein crystallization, drug development, and biosensors. The importance of adjusting ion strength Ionic strength is a measure of the concentration of ions in a solution and is a function of the concentration of all ions in the solution. When ionic compounds dissolve in water, they dissociate into ions, and the concentration and charge of these ions together determine the ionic strength of the solution. The magnitude of ionic strength directly affects the behavior and properties of biomolecules in solution. For example, ionic strength can affect the solubility, stability, conformational changes, and interactions with other molecules of proteins. In biochemical experiments, in order to obtain accurate and reproducible experimental results, it is necessary to strictly control the ionic strength of the solution. BES, as a zwitterionic buffer, has excellent buffering performance and biocompatibility, and can effectively absorb or release protons (H+) in a wide pH range, thereby maintaining the relative stability of solution pH. Meanwhile, by adjusting the concentration of BES, the ionic strength of the solution can be controlled, thereby affecting the behavior and properties of biomolecules. Application examples of BES in regulating ion strength In cation exchange chromatography, BES is used as a binding buffer and eluent, which can adjust the pH and ionic strength of the solution, affecting the binding and elution process of biomolecules with the chromatographic column. By adjusting parameters such as BES concentration, pH value, and ionic strength, the separation efficiency of cation exchange chromatography can be optimized. For example, increasing the concentration of BES can enhance the ionic strength of the solution and strengthen the binding force between biomolecules and the chromatographic column; Lowering the pH value can make biomolecules carry more positive charges and increase their affinity for cation exchange chromatography columns. In gel filtration chromatography, BES also plays an important role as a buffer. It can maintain the stability of the pH value of the solution, ensuring the stability and activity of biomolecules during the separation process. Meanwhile, by adjusting the concentration of BES, the ion strength of the solution can be controlled, thereby affecting the elution speed and separation efficiency of proteins. Appropriate ionic strength can enhance the interaction between protein and gel particles, extend the elution time of protein, and improve the separation efficiency. In addition, in protein crystallization research, BES as a buffer can adjust the pH and ionic strength of the solution, providing a suitable crystallization environment for protein molecules. High quality crystals not only help reveal the three-dimensional structure of proteins, but also provide important structural information for drug development. Conclusion In summary, the biological buffer BES plays a crucial role in regulating the ionic strength of solutions. Its excellent buffering performance and stability make BES an indispensable reagent in biochemical experiments. By precisely regulating the concentration of BES and the pH value of the solution, the process and results of various biochemical experiments can be optimized. In the future, with the development of biotechnology and structural biology, the potential of BES in regulating solution ion strength and promoting the research and application of biomolecules will be further explored and utilized. As a BES buffer raw material manufacturer, Desheng has advanced production technology and strict quality management system. The BES raw materials produced have high purity and stable quality, which can meet customers' demand for high-quality products. At the same time, Desheng focuses on technological innovation and research and development, continuously optimizing production processes,

Against the backdrop of the booming global healthcare market, the demand for medical consumables raw materials continues to rise. For global buyers, it is crucial to find a supplier that can provide high-quality and comprehensive medical consumables raw material solutions. Hubei Xindesheng Material Technology Co., Ltd., as a leader in the industry, will appear at the 2025 Türkiye International Medical Device Exhibition, bringing unprecedented cooperation opportunities to global buyers. 1, Enrich product line to meet diverse needs Hubei Xindesheng Material Technology Co., Ltd. has been deeply involved in the field of medical consumables raw materials for many years, and has built a rich and complete product line. The company focuses on the research and production of in vitro diagnostic reagents, mainly including biological buffering agents, chemiluminescence reagents, chromogenic substrates, and a full range of blood collection tube additives. These products have rich research and development experience and mature production lines. Professional technicians and advanced equipment can provide customized services and technical support. In addition, in the past two years, the company has focused on the research and development of diagnostic enzymes and established a professional technical team. Currently, pyruvate kinase, cholesterol oxidase, uricase, adenosine deaminase, S-adenosyl-homocysteine hydrolase, and other enzymes have been successfully launched on the market. At the same time, the company is actively preparing for the construction of a new factory, expanding production lines, improving production capacity while reducing costs, and providing high-quality in vitro diagnostic products for its customers. 2, Excellent quality, forging industry reputation Quality is the lifeline of an enterprise, and Hubei Xindesheng Material Technology Co., Ltd. is well aware of this. The company strictly controls every aspect of raw material procurement, production and processing, quality inspection, etc., to ensure that products meet international standards and customer requirements. With excellent quality, the company's products not only occupy an important share in the domestic market, but also are exported overseas, serving the health and medical industry of people in various countries, and winning high recognition and good reputation from customers. Many well-known domestic and foreign medical device companies have established long-term and stable cooperative relationships with Xindesheng, which undoubtedly proves the best quality of the company. 3, Türkiye Exhibition Opens a New Chapter of Cooperation From April 24 to 26, 2025, the 32nd Türkiye International Medical Device Exhibition will be held in Istanbul TUYAP International Exhibition Center. As the largest medical exhibition in Eurasia, this exhibition attracts hundreds of exhibitors and tens of thousands of visitors every year. It is a leading exhibition of medical trade in Türkiye and Eurasia. Hubei Xindesheng Material Technology Co., Ltd. will showcase its one-stop medical consumables raw material solutions in all aspects at this exhibition, and have face-to-face exchanges with global buyers. In order to thank global buyers for their support and trust, the company has specially launched an exclusive offer for signing contracts at the exhibition site. Buyers who sign contracts with Xindesheng at the exhibition site will enjoy exclusive benefits such as price discounts, priority supply, and customized services. This is not only an opportunity for business cooperation, but also an opportunity to work together and create a better future. In today's rapidly developing global healthcare market, choosing a reliable supplier of medical consumables raw materials is the key to the success of buyers. Hubei Xindesheng Material Technology Co., Ltd. will become an ideal partner for global buyers with its rich product line, excellent quality, and exclusive treatment at the exhibition site. The 2025 Türkiye International Medical Device Exhibition looks forward to meeting with you to open a new chapter of cooperation in medical consumables!

Biological buffering agents play a crucial role in biochemical and molecular biology research. They can stabilize the pH value of the solution, providing an ideal environment for experimental processes such as enzymatic reactions, protein crystallization, DNA/RNA manipulation, etc. Bicine, as a common biological buffering agent, is highly favored due to its excellent buffering capacity and low interference with biomolecules. However, the chloride ion content, as an important indicator of Bicine buffer, has a significant impact on its performance and application effectiveness. The adverse effects of chloride ions on experiments Chloride ions, as a common anion, may bring some adverse effects in biochemical experiments. Firstly, high concentrations of chloride ions may cause non-specific reactions with other ions or molecules in the experiment, leading to deviations in the experimental results. Secondly, chloride ions may interfere with the conformation and stability of proteins, thereby affecting their function and activity. In addition, chloride ions may also affect the activity and stability of enzymes, thereby affecting the efficiency and accuracy of enzyme catalyzed reactions. The influence of chloride ion content on the performance of Bicine buffer 1. Maintain experimental stability The main function of Bicine buffer is to maintain pH stability during the experimental process. Strict control of chloride ion content can help achieve this goal. High chloride ion content may lead to unstable pH values, thereby affecting the accuracy of experiments. In contrast, Bicine buffer with low chloride ion content can more stably maintain the pH value of the solution, ensure the consistency of experimental conditions, and improve the stability and reliability of the experiment. 2. Improve experimental accuracy In experiments that require high-precision measurements, such as protein crystallization and enzyme activity assays, the presence of chloride ions may become a potential interfering factor. Bicine buffer with low chloride ion content can reduce this interference, avoid unnecessary experimental errors, and improve the accuracy of experimental results. 3. Protecting cellular health In cell biology experiments, the health status of cells directly affects the quality of experimental results. Buffer solutions with high chloride ion content may have toxic effects on cells, affecting their growth and function. Bicine buffer with low chloride ion content can effectively maintain the healthy state of cells, provide a good growth environment for cells, and ensure the reliability of experimental results. How to control the chloride ion content in Bicine buffer 1. Optimize raw material selection The chloride ions in Bicine buffer mainly come from the raw materials and preparation process. Therefore, in the selection of raw materials, low chloride ion raw materials should be chosen as much as possible to reduce the residual chloride ions in the finished product. 2. Improve the preparation process During the preparation process, the reagents, water sources, and other substances that may contain chloride ions should be strictly controlled. By improving the preparation process, such as using high-purity water sources, reagents, and more precise purification steps, the chloride ion content in Bicine buffer can be effectively reduced. 3. Strengthen quality inspection Strict quality testing of the finished Bicine buffer is crucial to ensure that its chloride ion content meets the standard. By using advanced analytical techniques such as high-performance liquid chromatography (HPLC), the chloride ion content in Bicine buffer can be accurately determined, and the preparation process can be adjusted in a timely manner to ensure product quality. Conclusion The chloride ion content, as an important indicator of Bicine buffer, has a significant impact on its performance and application effectiveness. By strictly controlling the chloride ion content, it is possible to maintain pH stability during the experimental process, improve experimental accuracy, protect cell health, and extend storage life. Therefore, in the preparation and application of Bicine buffer, full attention should be paid to the control of chloride ion content to ensure its optimal performance and application effect. In summary, the influence of chloride ion content on the biological buffer Bicine cannot be ignored. In future research and applications, we need to continue exploring more effective methods for controlling chloride ion content to further improve the performance and application value of Bicine buffer. The chloride ion content of bicine buffer produced by Hubei Xindesheng Material Technology Co., Ltd. is less than 0.1%, and all indicators meet relevant standards. In addition to bicine buffer, Desheng actively researches and develops dozens of biological buffers such as TRIS and hepes commonly used in the market. If you are interested, please click on the Desheng official website to learn more details!

In the spring of April 2025, Expomed Eurasia, a grand event attracting the attention of the global medical industry, will soon open in Istanbul. As a leader in the field of in vitro diagnostics (IVD) raw materials, Desheng New Materials will showcase its innovative product lineup at this exhibition (booth number: 829C5), aiming to exchange experiences and negotiate cooperation with global peers, and jointly promote the vigorous development of the medical industry. Türkiye Medical Exhibition: a bright stage for global medical industry exchange Expomed Türkiye Medical Exhibition is a very influential medical industry event in Europe, the Middle East and North Africa. This exhibition not only brings together medical equipment manufacturers, raw material suppliers, medical technology service providers, etc. from around the world, but also attracts the attention of numerous medical institutions, industry associations, and professionals. The exhibition will be held in Istanbul from April 24 to 26, 2025. This city with unique geographical location is not only the economic and cultural center of Türkiye, but also an important hub connecting the East and the West. During the exhibition, Desheng New Materials will fully utilize this platform to showcase its innovative technologies and products, and collaborate with colleagues in the global medical industry to create a new chapter in industry development. Desheng New Materials: Leading Industry Development with Technological Innovation From 2005 to 2025, Desheng New Materials has written a history of progress in China's IVD raw materials in twenty years. The company is based in Ezhou, Hubei and has a production base covering an area of 5000 square meters. It has a professional R&D team of 30 people, with over 80% of them holding doctoral and master's degrees. It is precisely this persistence that has enabled Desheng to grow from a start-up enterprise to a high-tech enterprise with a complete industrial chain. Desheng New Materials always adheres to the concept of "craftsmanship, quality, innovation driven", and is committed to providing customers with high-performance, low-cost, and domestically produced core raw materials. After 20 years of technological accumulation and market refinement, the company has developed into a high-tech enterprise that integrates research and development, production, sales, and service throughout the entire industry chain. Five core product series unveiled at the exhibition site At this exhibition, Desheng New Materials will showcase its five core product lines, including chemiluminescence series, biological buffer series, chromogenic substrate series, enzyme preparations, and antigen antibodies. These products are widely used in fields such as biochemical analysis, immune testing, molecular diagnostics, etc., providing stable and reliable raw material support for global customers. Chemiluminescence series: providing highly sensitive chemiluminescence immunoassay core materials, suitable for high-precision requirements such as tumor markers and infectious diseases. Biological buffer series: purity over 99.9%, batch difference less than 1%, widely used in PCR, gene sequencing, cell culture and other fields. Color substrate series: fast color development speed, low background value, supports customized formulas, and meets the needs of fully automatic biochemical analyzers and POCT equipment. Enzyme preparations: high activity, high purity, and stability, covering various testing items such as cardiovascular markers, infectious disease screening, tumor diagnosis, etc. Antigen antibody: There are up to a hundred types of products with high specificity and sensitivity, which can be used in fields such as immunology research, protein research, and disease diagnosis. Seeking common development and jointly creating the future On the stage of Türkiye Medical Exhibition Expomed Eurasia, Desheng New Materials looks forward to in-depth exchanges with colleagues in the global medical industry, to jointly discuss the development trend of the industry, and to share technological innovation achievements. We sincerely invite all allies to visit our booth (829C5) to explore the future of medical technology and work together to create a better tomorrow.