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Latest company new about Factors Influencing the Price of Extracorporeal Anticoagulant Heparin Sodium
2023/08/21

Factors Influencing the Price of Extracorporeal Anticoagulant Heparin Sodium

With the continuous development of medical technology and the widespread promotion of clinical applications, heparin sodium, as an important anticoagulant, can be added to blood collection vessels or prepared into drugs for use in fields such as cardiac surgery, hemodialysis, and intravascular therapy. However, the accompanying issue is the price of heparin sodium, which cannot be ignored in the market and involves the production cost of the company. The following will delve into the factors behind the price of heparin sodium and their impact.   Factors Influencing the Price of Heparin Sodium   1. Production cost: The preparation process of heparin sodium is relatively complex, involving multiple chemical synthesis steps and purification processes. The raw materials, instruments and equipment required in the production process will directly affect the production cost of the product, thereby affecting the final price setting.   2. Raw material price: Its preparation requires a series of raw materials, including organic compounds, pig small intestine, etc. The market price fluctuations of these raw materials will directly affect the production cost of heparin sodium, thereby affecting the price of the product.   3. Quality standards: High purity heparin sodium often requires strict quality control and testing, which involves more testing equipment and labor costs. Therefore, different quality standards require different production costs, which can also affect the final price.   4. Market competition: The market competition for heparin sodium is fierce, and competition between different manufacturers may lead to price fluctuations and decreases, which can also have an impact on product prices.   Changes in the price of heparin sodium   The price of heparin sodium is influenced by various factors such as market supply and demand, raw material prices, and medical demand, so it may fluctuate over a certain period of time. In addition, changes in the global market and adjustments in international policies will also have an impact on its prices.   Consideration of price rationality   When setting prices, in addition to considering production costs, it is also necessary to consider the rationality of the price. Price is not only related to the operational status of the production enterprise, but also to the rights and interests of users. A reasonable price should not only meet the reasonable profit of the production enterprise, but also fully consider the market's affordability.   Heparin sodium, as an indispensable reagent, has great significance in the medical field. Its price is influenced by various factors, including production costs, raw material prices, quality standards, and market competition. A reasonable price can not only reflect the value of the enterprise, but also protect the rights and interests of customers. As a manufacturer of heparin sodium, Desheng can provide affordable raw materials with excellent production and stable performance, which have been praised by manufacturers who have used it. If you are interested, you can also contact us to purchase!
Latest company new about porcine-derived heparin sodium
2023/08/18

porcine-derived heparin sodium

Heparin Sodium is a commonly used anticoagulant widely used in clinical medicine and laboratory research. It can not only be prepared into drugs to prevent the formation of blood clots, but also effectively inhibit blood coagulation in blood collection vessels. Blood samples treated with anticoagulation are suitable for various biochemical items. However, in addition to synthetic heparin sodium, there is also a natural source of heparin sodium, which is extracted from pigs. This article will introduce the characteristics and preparation process of heparin sodium extracted from pigs.   characteristic   The heparin sodium extracted from pigs is extracted from the intestinal mucosa of pigs. Compared with synthetic heparin sodium, it has the characteristics of naturalness and diversity. In the early stage, heparin was extracted from animal livers, but it was later discovered to exist in the small intestine of pigs. In addition, China's pig farming industry is developed, and it is naturally obtained from pig intestines, which is a natural source of anticoagulants. This also makes it more popular in certain specific application fields. Diversity indicates that there may be slight structural differences in heparin sodium from different sources, which may lead to different biological activities and bioavailability of heparin sodium extracted from pigs in certain situatio.   Preparation process   The preparation process of heparin sodium extracted from pigs involves multiple steps and techniques to ensure the production of high-purity heparin sodium products. The approximate steps are as follows:   1. Raw material processing: Firstly, extract the precursor substance of heparin sodium from fresh small intestine. After careful cleaning of the small intestine, the mucosa is scraped off and crushed into fragments, preparing for the subsequent steps.   2. Heating enzymatic hydrolysis: The chymosis mucosa is placed in a heating tank, with an appropriate amount of water added, followed by approximately 8% trypsin. Next, by gradually adding a weak alkaline solution, the pH of the solution is maintained between 8 and 10. The temperature gradually increases, first heating to 30-40 ℃, holding at this temperature for 2-3 hours, then heating to 50-60 ℃, holding for 10-20 minutes. The entire process requires maintaining the pH of the solution between 8.5 and 9.5.   3. Cooling adsorption: The solution after enzymatic hydrolysis is cooled to 30-40 ℃ and the surface oil is removed. Then, add the resin to the solution and stir for 6-7 hours to achieve the adsorption of heparin sodium. After adsorption, the resin is filtered out, carrying heparin sodium.   4. Elution: By adding a 10% mass fraction of sodium chloride solution, the adsorbents on the resin are eluted. This process is carried out at 50-55 ℃ and stirred continuously for 3-4 hours to ensure complete elution of heparin sodium from the resin. This step was repeated twice, and the two eluents were merged.   5. Sedimentation: The combined eluent is filtered and transferred to the sedimentation tank. Adjust the pH of the solution to 7-8 while adding 80-85% alcohol. Next, the solution is sealed for 10-12 hours to promote the formation of heparin sodium precipitate, which is then filtered out.   6. Dehydration and drying: The filtered sediment is placed in a drying oven for dehydration and drying. After this step, a high-purity pig extracted heparin sodium product was ultimately obtained.   Through the above preparation process, heparin sodium extracted from pigs was successfully prepared, and each step in this process requires strict control of conditions to ensure the final product quality. As a manufacturer of heparin sodium, Desheng can provide high content raw material powder, which is convenient and simple to use. When added to blood vessels for in vitro anticoagulation, its performance is stable. If you are interested, please feel free to contact us at any time!
Latest company new about Additives for blood collection heparin lithium as anticoagulant
2023/08/16

Additives for blood collection heparin lithium as anticoagulant

Blood collection is a common operation in clinical diagnosis and laboratory testing. To ensure that the collected blood samples accurately reflect the biochemical status of the body, appropriate anticoagulants need to be used to prevent blood coagulation. Heparin lithium, as a commonly used anticoagulant for blood collection, is widely used in clinical and laboratory settings. Below, we will explore the usage and precautions of heparin lithium as an anticoagulant for blood collection. Let's take a look together.   The mechanism of action of heparin lithium   Heparin lithium is a natural polysaccharide that primarily inhibits the activity of thrombin, thereby preventing the coagulation process. It can bind to antithrombin III, thereby inhibiting the formation of thrombin and inhibiting the coagulation cascade reaction. At the same time, it can also inhibit platelet aggregation by binding to coagulation factors on the surface of platelets.   Method of using heparin lithium as an anticoagulant for blood collection   Heparin lithium is usually injected into the blood collection vessel in the form of a solution to come into contact with the blood and achieve anticoagulant effects. When using heparin lithium, the following aspects need to be noted:   1. Appropriate concentration: The concentration of heparin lithium needs to be determined based on specific circumstances. Usually, in medical practice, the appropriate concentration of heparin lithium is determined based on the size of the blood collection vessel and the amount of blood required to be collected. The recommended amount for general industry standards is 9.4IU-28IU of heparin lithium per milliliter of blood. If using a peripheral blood sampler, anticoagulation needs to be less than 14IU per milliliter of blood.   2. Uniform mixing: Before using heparin lithium solution, it is necessary to thoroughly mix it evenly to ensure that heparin lithium is evenly distributed in the solution and ensure its anticoagulant effect is consistent.   3. Adding technique: When adding and preparing heparin lithium solution, it is generally divided into manual and machine adding. Machine adding requires setting machine parameters and paying attention to cleaning the pipeline to avoid impurities or bacterial residues. At the same time, it is necessary to timely check whether the dosage of the addition meets the requirements to ensure that the anticoagulant effect reaches the ideal state.   Matters needing attention   1. To ensure sufficient anticoagulation of blood samples, medical staff should invert and mix them as soon as possible after blood collection, without using excessive force, just gently invert 5 to 8 times.   2. The heparin lithium anticoagulant tube should be tested within 6 hours as much as possible, as it is a non irreversible anticoagulant. If not tested for a long time, it may lead to deviation in the test results.   3. Heparin is sensitive to indicators such as AST, ALT, and TBIL. It can participate in the metabolism of cellular enzymes and ions, and its usage may affect the detection results. Therefore, it is important to pay attention to the amount of heparin lithium tubes added during the detection project and select appropriate heparin lithium tubes according to different projects.   As an additive for blood collection, heparin lithium can effectively prevent blood coagulation during the blood collection process by inhibiting thrombin activity and reducing platelet aggregation, ensuring the quality of collected blood samples. Through scientific and reasonable use, heparin lithium will better exert its anticoagulant effect during blood collection, ensuring the accuracy of clinical diagnosis and laboratory testing.   As a manufacturer of heparin lithium, Desheng can provide raw material powder for manufacturers to prepare and add, with high main content and stable performance. 80% of test tube manufacturers will choose to cooperate with us. If you are also interested, please feel free to contact us at any time!
Latest company new about Additives for blood collection heparin sodium chemical name
2023/08/14

Additives for blood collection heparin sodium chemical name

Heparin Sodium, is an important anticoagulant widely used in the medical field. It is a polysaccharide compound composed of heparin sulfate. Due to its excellent anticoagulant effect, it is widely used in clinical practice to collect blood vessels or prepare drugs to prevent and treat thrombosis and other coagulation related diseases. The following will analyze the chemical properties, structure, and use of heparin sodium.   Chemical properties and structure   Heparin sodium is a natural polysaccharide, mainly composed of heparin sulfate. Heparin sulfate is a polymer composed of various amino sugars such as glucosamine and arginine. It contains a large number of sulfate groups, which endow heparin sodium with strong anticoagulant effects. Its chemical structure is complex, with different molecular weights of heparin sulfate ranging from thousands to hundreds of thousands. For example, the average molecular weight of heparin sodium, a blood vessel anticoagulant, is around 15000, while the drug heparin sodium is around 5000.   The use of heparin sodium   1. Anticoagulant therapy: Heparin sodium, as an effective anticoagulant, is commonly used to prevent and treat thrombosis, especially in postoperative and severely traumatic patients. It can prevent the activation of coagulation factors and platelet aggregation, thereby preventing the formation of thrombosis.   2. Hemodialysis: It is widely used in the process of hemodialysis to prevent blood clotting within the dialysis device through anticoagulation.   3. Heart surgery: In heart surgery, heparin sodium is commonly used to prevent intraoperative blood clotting and maintain blood flow. In special circumstances, such as high-risk diseases or surgeries, heparin sodium can be used to prevent the occurrence of blood clotting.   4. Endovascular therapy: In interventional endovascular therapy, heparin sodium can prevent instruments such as catheters and stents from forming blood clots in the blood vessels.   5. In blood collection vessels: used for anticoagulation treatment of blood, often in the form of raw powder on the market. When used, it needs to be prepared into a solution and added to a test tube to keep the blood sample in its original flow state, which is conducive to various biochemical tests, such as liver and kidney function testing.   Precautions for use   1. Dose adjustment: The dosage of the drug heparin sodium needs to be adjusted according to the patient's condition and use to ensure its anticoagulant effect and safety. The amount of heparin sodium added to the blood collection vessel needs to be according to the standard amount, such as adding 12-30IU of heparin sodium per milliliter of blood.   2. Anticoagulant monitoring: When using the drug heparin sodium, it is necessary to regularly monitor the patient's coagulation indicators to ensure that the anticoagulant effect is within a safe range.   3. Attention time: Heparin anticoagulation is non irreversible, so the heparin sodium anticoagulant tube should be tested within 6 hours after blood collection, otherwise it may cause problems in the test results.   Heparin sodium, as an important anticoagulant, plays an important role in the medical field. Although heparin sodium has broad application prospects, caution should also be taken when using it, and it is recommended to choose a supplier with reliable quality. As one of the suppliers of heparin sodium, Desheng can provide stable raw material powder for anticoagulation in blood collection, which is not suitable for disease treatment. It should be clear that the purpose can be explained in advance when purchasing, making it easier to quote. Welcome to click on the website to inquire about details!
Latest company new about Differences in blood anticoagulants lithium heparin and sodium heparin
2023/08/08

Differences in blood anticoagulants lithium heparin and sodium heparin

Heparin is a commonly used anticoagulant, widely used in clinical medicine and biochemical experiments. Among them, heparin lithium and heparin sodium are the two most common heparin anticoagulants, with slight differences in structure and application. The following will compare and analyze these two types of heparin anticoagulants to help them better use.   1. Structural differences: Although both heparin lithium and heparin sodium can anticoagulate blood, there are differences in chemical structure and effective binding ions, resulting in differences in dissociation degree. Our company's heparin lithium is replaced from heparin sodium.   2. Anticoagulant activity: There is no significant difference in anticoagulant activity between heparin lithium and heparin sodium. Both can effectively inhibit the activity of thrombin, block the coagulation process, and thus have an anticoagulant effect. In clinical use and biochemical experiments, the two can usually replace each other.   3. Application field: Heparin lithium and heparin sodium are widely used in different fields. In addition to being able to perform in vitro anticoagulation, heparin lithium is also commonly used in fields such as cardiac surgery, hemodialysis, intravenous infusion, and venous catheterization. Heparin sodium, on the other hand, mainly appears in the form of anticoagulants for blood collection, protecting the cells and proteins in the blood collection sample from interference from coagulation and maintaining the original characteristics of the sample.   4. Storage stability and usage: Lithium heparin and sodium heparin have their own advantages in terms of storage stability. As long as stored in dry and dark conditions, they can maintain their anticoagulant activity for a long time. In addition, special attention should be paid to its dosage and usage method. Excessive use may lead to poor anticoagulation effect, and industry standard dosage should be followed. The dosage range of heparin lithium in the industry standard is 9.41-281U units/ml, while heparin sodium is 121U-301U per milliliter of blood.   Heparin lithium and heparin sodium are common heparin anticoagulants, although they are both anticoagulants, there are also differences. When using them, it is necessary to choose appropriate anticoagulants based on the specific situation, and pay attention to their storage stability and dosage to ensure safe and effective application in clinical and experimental settings. As a manufacturer of blood collection additives, Desheng can provide high-quality heparin sodium and heparin lithium, but both are analytical grade and added to test tubes for in vitro anticoagulation use. It cannot be used as a drug. This needs to be understood clearly. Welcome interested parties to contact us anytime to purchase!
Latest company new about heparin sodium mechanism of action
2023/08/07

heparin sodium mechanism of action

Heparin sodium is a commonly used anticoagulant for blood collection, widely used in clinical blood collection and medical testing. Its mechanism of action mainly involves thrombin and antithrombin in the coagulation system, achieving anticoagulant effects through specific molecular structures and biological functions. The following will delve into the mechanism of action of heparin sodium to better understand its application in blood collection.   The Chemical Structure and Biological Activity of Heparin Sodium   Heparin sodium is a natural polysaccharide compound with complex and diverse chemical structures. It is mainly composed of glucosamine and glucuronic acid units, which form a specific polysaccharide chain structure through sulfation reaction. This special structure endows heparin sodium with anticoagulant biological activity.   Anticoagulant mechanism   The anticoagulant mechanism of heparin sodium is mainly achieved through the following aspects:   1. Inhibition of thrombin: Heparin sodium can form a stable complex with thrombin, thereby inhibiting the activity of thrombin and hindering its role in the coagulation process, thereby inhibiting the process of blood coagulation.   2. Promoting anticoagulant enzyme activity: Heparin sodium can also enhance the activity of antithrombin (such as antithrombin III), further inhibiting the activation of the coagulation system, and maintaining the blood in an anticoagulant state.   3. Inhibition of coagulation factor binding: It can inhibit the binding of coagulation factors in the liver, thereby reducing the tendency for blood clotting.   4. Inhibition of platelet aggregation: By inhibiting platelet aggregation and adhesion, the deposition of platelets on the inner wall of blood vessels is reduced, further slowing down the process of blood coagulation.   Advantages of heparin sodium   1. Quick action: Heparin sodium has a rapid anticoagulant effect and can achieve anticoagulant goals in a short period of time.   2. Widely applicable to biochemical projects: Blood samples processed with heparin sodium are suitable for various biochemical tests, such as liver and kidney function testing, blood glucose testing, and other biochemical categories in various medical scenarios.   Heparin sodium, as an effective anticoagulant for blood collection, its mechanism of action mainly involves multiple aspects such as inhibiting thrombin, promoting antithrombin activity, inhibiting coagulation factor synthesis, and inhibiting platelet aggregation. However, an important point in the anticoagulation treatment process is the need for stable and reliable heparin sodium raw materials. It is recommended to choose high-quality manufacturers, such as Desheng. Desheng has always been focused on the production of blood vessel additive raw materials, with strict requirements for various indicators of heparin sodium and obvious anticoagulant effects. If you have any related needs, please contact us to purchase!
Latest company new about Classification of heparin sodium
2023/08/03

Classification of heparin sodium

Heparin sodium, as a commonly used Anticoagulant in clinic, can not only be added to blood collection vessels to prevent blood coagulation, but also can be used as a drug to effectively prevent thrombosis and reduce the incidence of cardiovascular and cerebrovascular diseases. According to different preparation methods and structural characteristics, heparin sodium can be divided into various types. Next, we will introduce the classification of heparin sodium in detail.   Classification according to preparation method   1. Natural heparin sodium: a Natural product mainly extracted from pig intestines, bovine lungs and other animal viscera. After complete extraction of heparin, it is refined to obtain heparin sodium with high purity. Its production requirements are strict, and it is usually added to the blood collection vessel for use, with relatively stable performance.   2. Synthetic heparin sodium: obtained through chemical synthesis, it has high yield and cost advantages. Currently, polymer method and metal organic compound method are mainly used in the market for synthesis, and its performance and usage are far inferior to the first naturally prepared heparin sodium.   Classification based on structural features   1. Ordinary heparin sodium: Ordinary heparin sodium is a high molecular weight heparin containing multiple repeating units, appearing in the form of a drug. Its anticoagulant effect is good, but its bioavailability is low, and it is prone to side effects. It is rarely used in clinical practice.   2. Low molecular weight heparin sodium: Low molecular weight heparin sodium is a short chain heparin obtained through chemical modification, with high bioavailability and suitable for intravenous injection. Due to its direct contact with the human body, it not only requires high production requirements and expensive prices, but also requires obtaining corresponding certificates before production, and is subject to the supervision of the Medical Commission.   3. Heparin sodium salt: it is a kind of raw material heparin sodium, which is mainly extracted from pig intestinal mucosa, and then obtained through ion exchange adsorption. Its average molecular weight is about 15000, and its potency is between 150IU-180IU. It is generally of non injection grade. It is prepared into a solution and added to the blood collection vessel as an in vitro Anticoagulant.   Classified by purpose   1. Medical heparin sodium: medical heparin sodium includes medical heparin sodium and extracorporeal Anticoagulant heparin sodium, which are mainly used in cardiac surgery, hemodialysis, vascular interventional therapy and other fields, with strong anticoagulant effect and therapeutic effect. While the external Anticoagulant heparin sodium is used clinically, the main purpose is to help blood coagulate quickly in blood collection and improve the inspection efficiency of medical staff.   2. Industrial heparin sodium: This type of heparin sodium is generally low in purity, contains impurities, has low production requirements, and is cheap. It is mainly used in the manufacturing of industrial products such as cellulose and paper.   Different types of heparin sodium have different characteristics and application ranges, and selecting the appropriate type of heparin sodium needs to be considered based on the specific usage. As a professional manufacturer of heparin sodium, Desheng's product type is analytical pure heparin sodium salt, which is mainly used as an in vitro Anticoagulant and cannot be used for human body. If you are interested, you can indicate the use needs in advance to facilitate customer service to give you accurate quotations. Feel free to contact us at any time.
Latest company new about Heparin sodium per kg price
2023/08/01

Heparin sodium per kg price

Heparin sodium is an important chemical reagent that can be widely used as an additive for blood collection in clinical medicine, and also has a certain role in scientific research. The high level of its popularity represents market demand, which inevitably varies in price and is affected by various factors, such as production process, price, and manufacturer scale. Let's take a look at the factors that affect the price of heparin sodium per kilogram?   1. Production process: Heparin sodium is a reagent obtained by fine extraction and purification of natural heparin. Its production process is complex and requires advanced technology and equipment. The high investment in equipment increases costs, and the price of heparin sodium will also be affected.   2. Raw material cost: Its production requires a large amount of raw materials, including heparin from animals (such as pig intestinal mucosa). However, incomplete statistics are required. Only 3000 pigs can extract 1kg of heparin. If the number of live pigs is small, it is also an important factor affecting the price of heparin sodium.   3. Production scale: Production scale is another important factor affecting the price of heparin sodium. Mass production can reduce the production cost per unit product, thereby lowering the price of the product. Therefore, generally larger manufacturers are able to provide more competitive prices.   4. Market competition: As a commonly used Anticoagulant, the market competition is fierce, and the competition between different manufacturers will also affect the product price. In a highly competitive market, manufacturers may lower product prices to compete for market share.   5. Quality certification and standards: As a clinical reagent, heparin sodium must comply with strict quality certification and standards. Products that have passed quality certification and compliance standards are usually priced higher, but their quality and safety are also more guaranteed.   As an important Anticoagulant, heparin sodium is widely used in clinical medicine and scientific research. Its price per kilogram is affected by many factors. When choosing heparin sodium suppliers, in addition to price, everyone should also pay attention to product quality and supply capacity to ensure that the purchased products are safe, reliable, and meet the requirements.   As a raw material manufacturer of blood vessel additives, Desheng has always pursued quality first, so it strictly controls the quality of heparin sodium in the upper layer, fully protecting customer rights and interests. As a manufacturer, it can negotiate prices based on quantity, and the more orders placed, the greater the discount. If you are interested, please feel free to contact us for purchase!
Latest company new about Edta dipotassium salt molecular weight
2023/07/31

Edta dipotassium salt molecular weight

Nowadays, with the improvement of living standards, people are paying more and more attention to their physical health status, and the demand for physical examinations is also increasing. During a physical examination, blood analysis is a necessary item to be checked. When carefully observing the blood collection vessels, it can be observed that each type of blood collection vessel cap has a different color. This is because different reagents are added to tubes of different colors, such as blood collection tubes with Anticoagulant, coagulant and no reagent.   At present, the widely used reagent is Ethylenediaminetetraacetic acid dipotassium salt, which is one of the Anticoagulant and can prevent blood coagulation. However, the basis for its effectiveness depends on performance, such as molecular weight, pH value, solubility, or main content. So next, let's introduce this aspect to everyone.   Properties of dipotassium Ethylenediaminetetraacetic acid   Its appearance is white crystalline powder, without a pungent odor, and is easily soluble in water. As the finished product is a powder, it is easy to absorb moisture, with an average molecular weight of 404.6 and a pH value of 4.8 ± 1 in a 5% aqueous solution. The solubility in water is ≥ 60%, and it is of analytical purity grade, with a main content of over 99%. Adding it as a solution to a test tube has strong stability and can effectively protect blood components from damage.   Anticoagulant mechanism of dipotassium salt of Ethylenediaminetetraacetic acid   Because it needs to be prepared into a solution when added to a vacuum test tube, Ethylenediaminetetraacetic acid and Ethylenediaminetetraacetic acid anions can be dissociated on this basis. They can effectively chelate calcium ions in the blood, control calcium ion reaction from the source, prevent internal and external coagulation process, so as to achieve the purpose of blood coagulation and inhibit platelet aggregation. At the same time, compared with other anticoagulants of the same type, Ethylenediaminetetraacetic acid dipotassium has the smallest effect on blood cell composition and high solubility, so it is also a rational Anticoagulant that is highly respected in medicine.   Determination of pH value, main content, and solubility   In addition to the molecular weight that can represent the overall mass of Ethylenediaminetetraacetic acid dipotassium salt, the pH value, main content and solubility are also important. The measurement method is as follows:   1. Determination of main content: weigh an appropriate amount of sample, add water and ammonium chloride solution to fully stir and dissolve, then add an appropriate amount of Eriochrome Black T indicator, titrate with Zinc chloride standard titration solution until the solution turns red and purple, and then calculate the content according to the calculation formula. Desheng Ethylenediaminetetraacetic acid dipotassium salt is a dihydrate, so the main content may be higher than 100, which is normal.   2. PH measurement: Dissolve an appropriate amount of the sample to be tested in pure water, stir at room temperature for about 5 minutes, and then use a pH meter to measure it.   3. Solubility measurement: Take an appropriate amount of the sample to be tested and dissolve it in pure water. Stir at room temperature for 5-10 minutes to observe if it is completely dissolved.   As a superior supplier of Ethylenediaminetetraacetic acid dipotassium salt, Desheng has not only high purity and stable performance, but also independent production lines and large warehouses for spot sale. If you are interested, please click the website for consultation and purchase!  
Latest company new about The main characteristics and uses of the additive sodium heparin liquid for blood collection
2023/07/28

The main characteristics and uses of the additive sodium heparin liquid for blood collection

Heparin sodium is an important biomedical compound that, as a polysaccharide compound, has anticoagulant and anti-inflammatory effects and is widely used in clinical medicine and laboratory research fields. Due to its special role in medical and life sciences, it is important to have a deep understanding of its structure, uses, and characteristics. Below, we will give you a specific introduction around this aspect.   Molecular structure and chemical properties   Heparin sodium is a polysaccharide compound, which is composed of monosaccharide units such as Glucuronic acid and N-acetylglucosamine. Its main feature is that the molecular chain contains Organosulfate groups, which endow heparin sodium with strong anticoagulant ability. Because of its complex and diverse molecular structure, heparin sodium has broad application prospects in the medical field.   The use of heparin sodium liquid   Heparin sodium can be prepared as a drug or used as an additive, and its drugs are commonly used in clinical anticoagulation therapy, prevention and treatment of thrombosis. In cardiovascular surgery, hemodialysis and Pulmonary embolism, heparin sodium liquid is used for intravenous injection to reduce blood coagulation and prevent thrombosis. The additive, on the other hand, dissolves the original powder, then sprays it onto the inner wall of the test tube and dries it. It performs anticoagulant treatment on blood samples in vitro and is suitable for various biochemical tests, such as liver and kidney function testing.   The main characteristics of heparin sodium   1. Anticoagulant properties: The main characteristic of heparin sodium is its powerful anticoagulant effect, which inhibits blood coagulation reactions by binding with anticoagulant factors, thereby reducing the risk of clinical occurrence.   2. Safety: Heparin sodium injection liquid is widely used in clinical practice, and its safety has been fully verified. However, during use, attention should be paid to dosage and medication monitoring to prevent potential adverse reactions.   3. Stability: The solution is stored in a cool and dry place, not exposed to air, and has good stability.   Heparin sodium, as an important anticoagulant reagent and laboratory reagent, plays a crucial role in the fields of medicine and life sciences. To ensure its safety and effectiveness, attention should be paid to the dosage, usage, and storage conditions when using heparin sodium.   As the raw material manufacturer of heparin sodium, Desheng has strict requirements on its solubility and simple preparation, but it should be noted that its heparin sodium is used as a Anticoagulant for blood collection and cannot be used as a drug to treat any disease. If you have the need to purchase heparin sodium raw materials, please feel free to contact us for purchase!
Latest company new about In vitro blood Anticoagulant heparin sodium use
2023/07/26

In vitro blood Anticoagulant heparin sodium use

Heparin sodium is often used as a Anticoagulant in blood collection vessels. It can effectively prevent blood clotting and ensure that the collected blood sample remains liquid in proper time to provide accurate detection results. So how should it be used and what are the advantages of using it? Below, we will provide a specific analysis around this aspect to help everyone better understand and correctly use heparin sodium as an additive for blood collection.   Usage method   1. Addition method: Due to the original nature of heparin sodium as a powder, it needs to be prepared into a solution and added to a test tube. It can be dissolved in deionized water, and mixed evenly after the volume is fixed. After checking that the relevant values meet the standards, the machine can be used to adjust the parameters before adding. It can be coated in small batches on the inner wall of the blood collection vessel to ensure uniform distribution.   2. Dose added: the standard range of heparin sodium used in Vacutainer is 12-30IU per milliliter of blood. If it is micro blood collection, it should be reasonably adjusted according to the volume and type of blood collection vessel to ensure proper anticoagulant effect.   Advantages of heparin sodium in blood collection vessels   Heparin sodium can effectively prevent blood clotting, maintain the state of blood samples, and ensure the stability of blood components. Meanwhile, due to its widespread clinical application and long-term validation, it has a certain degree of safety and will not affect blood samples. In addition, after anticoagulation treatment with heparin sodium, it can be applied to a variety of tests, including routine Blood test, biochemical analysis and immunological tests. During the process of blood preservation, it can prevent the blood sample from being damaged by external influences.   Precautions for use   1. Dose control: The dosage of heparin sodium should be adjusted based on the volume and type of blood collection vessel to avoid excessive use.   2. Storage conditions: Heparin sodium raw material powder should be stored in a dry and cool place, avoiding direct sunlight and high temperatures.   3. Inverted mixing: To ensure sufficient coagulation of the blood sample, it should be inverted and mixed as soon as possible after blood collection, especially when the ambient temperature exceeds 25 degrees Celsius. Timely operation is necessary.   4. Due to the non irreversible anticoagulation of heparin sodium tubes, testing should be completed within 6 hours after blood collection is completed as soon as possible, otherwise it may lead to errors in the results.   As an additive for blood collection, heparin sodium plays an important anticoagulant role in the blood collection process, ensuring the stability and accuracy of blood samples collected. When using, attention should be paid to the dosage and storage method. Proper use and handling of heparin sodium can help improve the safety of the blood collection process and the quality of blood samples.   As a professional supplier of heparin sodium, Desheng can not only provide high-quality products, but also offer more favorable prices in large quantities, especially for customers who purchase in batches. It can achieve significant discounts. If you are interested, please feel free to contact us for purchase!  
Latest company new about Heparin sodium extraction
2023/07/21

Heparin sodium extraction

Heparin sodium is an important Anticoagulant. Based on the anticoagulant principle, it can be used for both external and internal anticoagulation. No matter what type of anticoagulation, it needs to rely on the quality of heparin sodium. The prerequisite for controlling quality is to have excellent production and strict requirements at the source. In this regard, the following will focus on introducing the extraction of heparin sodium and related application precautions.   Extraction method of heparin sodium   According to research, there are various methods for extracting heparin sodium, among which the most common are the following three:   1. Animal derived heparin extraction: Heparin is mainly extracted from the lungs, intestines, and other tissues of animals (such as cows, pigs, etc.), and then subjected to enzymatic hydrolysis, precipitation, washing, and purification steps to prepare heparin sodium for use. This is also a commonly used extraction method by most manufacturers at present.   2. Fermentation method: Large scale fermentation production is carried out by microorganisms (such as fermentation bacteria), and heparin is extracted from the heparin binding substance in the culture medium. This method is relatively rare and generally requires low production requirements.   3. Synthetic method: In recent years, with the development of chemical technology, the method of artificially synthesizing heparin has gradually matured, and heparin can be obtained through synthetic methods. This method is generally used by more mature manufacturers, and its production process is relatively complex.   Application of heparin sodium   1. Anticoagulant therapy: As a Anticoagulant, heparin sodium can be prepared into drugs and widely used in the prevention and treatment of cardiovascular diseases, Deep vein thrombosis and other diseases. Thrombosis can be prevented by inhibiting the activity of coagulation factors.   2. Blood anticoagulation treatment for blood collection: This anticoagulation is generally performed in vitro and mainly affects the blood. Blood treated with heparin sodium is suitable for various routine examinations in clinical practice.   3. Laboratory research: Heparin sodium is also used in certain experiments in biomedical research, such as blood agglutination inhibition experiments.   Precautions for extracting heparin sodium   1. High purity requirements: As a Anticoagulant, the purity and quality of heparin sodium are very important. During the extraction process, each step needs to be strictly controlled to ensure that the purity and quality of the product meet the standard requirements.   2. Optimization of reaction conditions: In response to the requirements of extraction methods, it is necessary to optimize reaction conditions, such as temperature, pH value, enzyme selection and concentration, in order to achieve high extraction efficiency and purity.   3. Extraction process monitoring: During the extraction process, key parameters such as heparin content and coagulation time should be regularly monitored to ensure the effectiveness of the extraction.   By using reasonable extraction methods and strict quality control, high-quality heparin sodium products can be obtained. Desheng, as a professional manufacturer of heparin sodium, is mainly extracted from the small intestinal mucosa of pigs, which is made into heparin sodium raw material and used as an in vitro Anticoagulant in test tubes. If you are interested, please contact us to purchase!
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