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Latest company new about How to Add the Blood collection tube additives into the Tubes?
2023/03/22

How to Add the Blood collection tube additives into the Tubes?

Nowadays, with the popularization and use of vacuum blood collection tubes, blood collection tube additives have also become hot products.Due to the different raw materials and production technologies of various manufacturers, their quality has also become uneven. So the following will focus on introducing the methods of adding blood collection tube additives to the test tube, which can also help you to use it for reference.   1. Serum separating gel filling Serum separation gel can be added by machine or manual. If it is produced in large quantities, it is generally added by machine. The addition steps are: (1) Put the separating gel into the hopper of the automatic or semi-automatic gel adding machine, and cover the hopper after the colloid is leveled. (2) Exhaust the air bubbles. After adding the gel, place the test tube with the gel upright for 8-12 hours, and then seal it and evacuate it. If air bubbles appear, use a centrifuge at 800-1200g centrifugal force for 2-5 minutes to expel air bubbles. (3) Stand still, no matter adding gel or extracting a vacuum, the thixotropy of the separation gel will temporarily decrease during the centrifugation process, so the test tube should be placed for more than 1 hour after adding gel and centrifuging.   2. Anticoagulant addition Since there are many types of anticoagulants, including heparin sodium, heparin lithium, EDTA K2, EDTA K3,EDTA 2Na,etc.Their addition methods have many similarities, so let’s take heparin sodium and heparin lithium as an example. 1. Machine addition: (1) Cleaning: Before using the machine, clean the utensils and delivery pipes, first rinse with deionized water, then spray with 80% alcohol for cleaning, then use more than 99% ethanol for secondary cleaning, and then use hot air Just blow dry. (2) Machine adjustment: determine the quantity or volume of heparin sodium or heparin lithium that needs to be added according to the volume of the blood collection tube to be produced, adjust the flow regulator of the machine to an appropriate value, add 10-100 test tubes, and randomly check whether the dosage meets the requirements. 2. Manual addition: (1) Clean the containers and tools prepared for dispensing heparin sodium or heparin lithium solution, the method is the same as that of the machine. (2) Dispense heparin sodium or heparin lithium solution into cleaned containers and distribute them to operators together with cleaned and adjusted pipettes. Pay attention to adjust the scale of the pipette to ensure that the added solution meets the specified requirements. (3) Use a pipette to add heparin sodium or heparin lithium solution into the blood collection tube, and confirm the amount added and perform random inspection.   As a raw material supplier of blood collection tube additives, Desheng can provide a full range of products, including serum separation gel, heparin sodium, heparin lithium, EDTA K2, EDTA K3,EDTA 2Na, siliconizing agent, sodium citrate, etc. These products are of analytically pure grade and can meet most of the experimental requirements. If you are interested, welcome to consult!
Latest company new about What are the requirements for blood sampling additives?
2023/03/21

What are the requirements for blood sampling additives?

Serum separating gelWhat are the requirements for blood sampling additives?       In the laboratory of a hospital, you can see various test tubes. These tubes are not only used to store blood, but also can serve as an auxiliary test. Why do you say that? This is because reagents are added to it, such as commonly used serum separation gel, EDTA dipotassium, heparin sodium, heparin lithium, etc. What are the requirements for the use or addition of these blood collection additives? Below is a detailed explanation for everyone.       1、 Serum separating gel       First of all, there are requirements for temperature during the use process. Due to low temperature and increased viscosity, it may be difficult to add glue. The recommended temperature range is between - 20 -+90 degrees. If it is too low, you can also use a water bath for heating treatment. In addition, there are also requirements for the amount of separation gel added to the test tube, with a standard addition amount of 0.8-1.2g. For a tube with a diameter of 16mm, the amount of gel added should be above 1.0-1.2g.   Serum separating gel         2、 Anticoagulant       There are many types of anticoagulants. Let's take heparin sodium, heparin lithium, and EDTA dipotassium as examples to highlight the following requirements.       1. Heparin sodium, heparin lithium       The requirement is mainly for use in test tubes. To ensure sufficient anticoagulation of blood, it is necessary to slowly invert and mix for 5-8 times immediately after the completion of blood collection. Especially when the blood collection environment is high, if insufficient anticoagulation is not possible, it can easily lead to local coagulation. In addition, due to its non irreversible anticoagulation, it is necessary to complete the test within 6 hours after blood collection, and cannot be placed on hold for a long time, otherwise the results are prone to errors.       2. EDTA dipotassium       The requirement in testing is that after collecting the blood sample, it should be inverted 5-8 times as soon as possible to prevent the formation of small blood clots. It is also non irreversible anticoagulation like heparin, so it is required to complete the test within 24 hours. In addition, there are also requirements for the amount of potassium EDTA added, adding 1.5-2.2 mg of potassium EDTA solution per milliliter of blood. When used with other reagents, the addition requirement is to add 1.2-2.0 mg of potassium EDTA solution per milliliter of blood.       3、 Coagulant accelerator       The main requirement is to ensure that the clotting time is around 5-15 minutes before centrifugation. Direct centrifugation is not allowed, which can easily cause fibrin filaments to precipitate, and the detection effect is poor. Moreover, there are requirements for the addition amount of coagulant promoting agents. The addition standard is 20-30 Ul, which can promote the coagulation of 2-5 ml of blood. If the ambient temperature is too low or the blood collection volume is too high, it is necessary to appropriately increase the addition amount of coagulant promoting agents.       As a professional supplier of blood collection additives, Desheng has established its own reputation and image in the Chinese market, and is also the only manufacturer of a full range of blood collection additives. It can provide one-stop procurement for customers without having to travel around. If you have any interested parties, please click on the website for details!
Latest company new about Will blood sampling additives affect test results?
2023/03/20

Will blood sampling additives affect test results?

  Will blood sampling additives affect test results?       With the advancement of medical development, clinical testing technology has also been improved, and the corresponding biochemical testing index requirements have become strict. As an important reagent in testing, the appearance of blood sampling additives has effectively improved the overall testing level. Currently, the additives for blood sampling appearing on the market include various categories, such as serum separation gel, heparin sodium, heparin lithium, EDTA dipotassium, tripootassium, disodium, coagulant enhancer, silicifying agent, etc. Do so many additives have any impact on the test results? Let's focus on this aspect and introduce it to you.       In fact, whether additives have an impact on the test results is related to their performance and use:       1、 Serum separating gel        In a test tube, it can achieve rapid turnover with the aid of a centrifuge, separating serum from blood cells, not only ensuring the stability of serum chemical components, but also facilitating the effective extraction of high-quality serum samples by medical personnel. However, relying solely on the function of an external force centrifuge is not enough. It also depends on its own performance. Its specific gravity should be maintained between 1.045-1.065g/cm3, exhibiting physiological inertia, and having good thixotropy can effectively ensure the smooth testing process and unaffected testing results. (EDTA dipotassium anticoagulant)       2、 Anticoagulant       As a frequently used reagent in clinical testing, anticoagulants include various types, such as heparin sodium, heparin lithium, EDTA potassium salt, and disodium salt. When they come into contact with blood in a test tube, they can prevent blood coagulation without destroying the components of the blood sample. If you want to ensure that test results are not affected, you need to pay special attention to their performance indicators:       1. Heparin salt: The main performance indicators for measuring heparin salt are its average molecular weight and potency. When added to a test tube, it must reach a molecular weight of 15000 and a potency of 150-180 IU. When using, pay attention to the dosage added, which will have no impact on the test results.      2. EDTA potassium salt: This is an internationally recognized ideal anticoagulant reagent, but its effectiveness depends on its purity and stability. Reagent raw materials should be of analytical purity, maintained above 99%, and have strong stability when in contact with other reagents or blood, which can also ensure the accuracy of the test results.       3、 Coagulant accelerator, silicifying agent       Coagulant promoters and silicifying agents are also commonly used in test tubes. One is to promote rapid blood coagulation, and the other is to treat the tube wall to ensure no wall sticking. The direct factor that can affect the test results is poor quality. If the coagulant does not play a strong role, the blood cannot completely coagulate, and half of the coagulation generally does not coagulate during the final test, so the results are undoubtedly inaccurate. The same is true for silicified agents. When blood remains on the wall of the tube, causing damage to blood cells, the overall result will be biased.       Therefore, from the above introduction, the performance of blood sampling additives is a key factor affecting the results. If you want to use high-quality additive products, you can choose Desheng. It has a professional research and development team and a quality inspection department, which will continuously track foreign export products to ensure customer satisfaction. Interested parties are welcome to click on the website for consultation!  
Latest company new about Which is the best place to collect blood vessel silicide?
2023/03/13

Which is the best place to collect blood vessel silicide?

Which is the best place to collect blood tube silicide?       Nowadays, there are more and more businesses of silicified agents for blood collection in the Chinese market. How to select a reliable business is the most important thing for customers, because a reliable business can not only ensure the quality of silicified agents, but also facilitate the stable supply in the later period, which greatly saves money and time costs.   Water-soluble silicifying agent       Silicified agent has always been used as the necessary treatment reagent for blood collection, and its requirements are high. Is there any business that can provide high-quality silicified agent? The answer is yes. Here we recommend Desheng, a high-quality silicified agent manufacturer. It has more than 10 years of research and development experience, perfect quality and product system, and one-stop service for customers. Now let me introduce to you in detail how good it is as a manufacturer of silicified agent?       1、 Manufacturer       Although there are many manufacturers of silicified agent in the market, many products are not produced and sold directly by manufacturers, and it is difficult to guarantee quality problems when using. Desheng has an independent factory, warehouse and production equipment as well as a professional delivery channel in China, an after-sales team, and an independent connection between customers and the factory, without the intervention of a third party. This can avoid the unsolvable situation of goods from the source, which is beneficial to both parties.       2、 Cost reduction       As a manufacturer, Desheng can save the purchase cost for customers, because most of them are sold at wholesale prices, especially in the case of large orders, it can give customers more room for profit and reduce the purchase cost far. However, middlemen will directly raise the price for the purpose of profit, and there is basically no room for bargaining. This is one of the reasons why most people choose manufacturers.       3、 Continuous supply of goods and perfect service       As a spot manufacturer of its own production line, Desheng can develop and produce independently, schedule its own production, coordinate quickly, and not be affected by other upstream manufacturers. The products can be supplied continuously to ensure that the market and customers have sufficient supply of goods, which is conducive to ensuring the delivery date and use of customers. In addition, in addition to the ability to produce and supply goods, of course, the service ability is also very important. The company specially sets up pre-job and post-job training, and all personnel can take up their posts after passing the assessment, and promise to return and replace goods. Before purchase, sample testing can be provided to ensure that customers can use at ease.       As an experienced manufacturer of silicifying agent in China, Desheng's water silicon and oil silicon are popular in China, and its sales are also increasing. If you have a purchase demand for silicified agent, please click the website for details!
Latest company new about China's vasculature silicification agent manufacturer
2023/03/10

China's vasculature silicification agent manufacturer

China's vasculature silicification agent manufacturer       As a kind of silicifying agent, the application of silicifying agent in vacuum test tubes is indispensable, which brings with it the increase of demand and the rapid "rise" of manufacturers producing silicifying agent in the market. This has both advantages and disadvantages for most people, which means that there are more choices and the product quality may also be threatened. Therefore, it is particularly important to find a reliable manufacturer of blood sampling silicide in China.       The following will focus on recommending a Chinese manufacturer of silicified agent, which you can choose as your first choice. Its silicification performance is stable, and the test tube is smooth and not rough. It is a hot product in the domestic market. In addition, there are some other advantages worth choosing. Let's take a look.       1、 Good effect of silicifying agent       Silicified agents are used in blood collection, and have high requirements for some key values, such as silicified content, density, boiling point or operation method. The silicified agent produced by Desheng will strictly comply with these R&D requirements, so that the prepared silicified agent can be sprayed into the test tube to ensure that there is no burr on the tube wall, and avoid the phenomenon of "hanging on the wall" when contacting with blood or other reagents, which is conducive to improving the overall detection efficiency and making the detection results more accurate.       2、 Direct production and direct sales by Chinese manufacturers       Although there are many manufacturers selling silicified agents, there are also many fake manufacturers, especially foreign customers, which are easy to identify. This not only leads to price increases, but also the quality of products has become a major problem. Desheng is a genuine Chinese manufacturer. Many foreign customers often make field visits, have independent plants and production equipment, and are equipped with a professional research and development team, which can solve the product quality problems that customers worry about in a one-stop way, and ensure the safe use.       3、 Timely delivery and sufficient supply       As a manufacturer of direct production and direct sales in China, with advanced production equipment, its daily production capacity can basically reach more than tons, and there are also spot sales in the warehouse to ensure the supply of goods to customers. Especially for customers who need to order in large quantities, they can deliver goods on the same day or the next day. Even if the distance is far, they will never let customers wait too long.       Since its establishment in 2005, Desheng has been devoting itself to research the raw material products of blood vessel additives. Its silicified agent can withstand the test of customers and the market, so it is highly praised and affirmed. At present, many foreign customers want to establish long-term cooperative relations with the company. If you also have needs, welcome to join us and we will not let you down!
Latest company new about How to use silicification agent for blood collection?
2023/03/09

How to use silicification agent for blood collection?

How to use silicification agent for blood collection?       As a necessary treatment reagent in blood collection, silicified agent usually exists on the surface of the test tube, which is not easy to be detected by the naked eye. Its main role is to ensure that the test tube is smooth and transparent, without burr, prevent wall hanging, and affect the overall beauty and test results. Although it is convenient and fast to use, some problems sometimes occur, such as poor silicification effect, rough test tube on one side, or deviation of test results. So we will focus on how to use it in this case.       Silicifying agent is divided into high-efficiency silicifying agent (oil silicon) and water silicon. The composition and performance of the two are different, so the use method will also be different. Please pay attention to distinguishing. Use method of high-efficiency silicifying agent:       1. Prepare and weigh an appropriate amount of silicifying agent, and then add a certain amount of petroleum ether. When the boiling range reaches 60-90 ℃ and the concentration is 0.5-1.0%, fully stir evenly.       2. The evenly stirred solution can be adhered to the inner wall of the test tube by spraying, soaking, and then placed for a short time.       3. After a short time of placing, the glass or plastic test tube can be fully drained with its nozzle facing down, and then placed at room temperature for about 3 hours to cure. After fully drying, other reagents can be added together.       4. Attention must be paid to adding other reagents after complete curing, especially when the reagent is a solution, if it is not fully cured, it is easy to dilute or mix, resulting in poor silicification effect.   Water-soluble silicifying agent       Use method of water-soluble silicide:       1. First prepare an appropriate amount of water-soluble silicifying agent, then add a certain amount of deionized water, fully prepare it into an aqueous solution of 0.5-1% concentration, and then mix well.       2. After preparation, completely dip the test tube into the mixed solution and take it out after a short stay.       3. Then fully drain the tube with its mouth down, or put it in an oven for drying, and then add other reagents.       The above briefly introduces how to prepare and use the silicified agent. As a treatment reagent for blood collection, its requirements must be stricter. Only by knowing how to use it can we effectively avoid problems in the results.       Desheng, as an old manufacturer of silicified agents in China, has been following the market for 18 years with its R&D experience. The oil silicon and water silicon produced by Desheng have always been the preferred products of domestic customers. At the same time, the company has a professional R&D team and after-sales team, which can solve the customer's order, delivery and product quality problems in the first time. If you have relevant requirements, please click the website for details!
Latest company new about What are the effects of silicifying agents on the detection of vacuum blood sampling?
2023/03/08

What are the effects of silicifying agents on the detection of vacuum blood sampling?

What are the effects of silicifying agents on the detection of vacuum blood sampling?       In recent years, vacuum blood collection has been widely used in clinical blood testing experiments. Because of its simple operation, clean and pollution-free, it is favored by major hospitals. However, in the whole process of clinical use, there are still some problems that will affect the smooth collection of blood samples, such as the use of additives is not in place or the quality of products.       As a professional reagent for vacuum blood collection, the use of silicified agent will also affect the detection efficiency to a certain extent, so let's focus on the introduction of silicified agent.       1、 Type of silicifying agent       In fact, there are many kinds of silicified agents used for the treatment of blood vessels. For example, they can be divided into soluble or insoluble in water, soluble in organic solution or insoluble in organic solution, and their viscosity also includes easily flowing liquid and semi-solid liquid. Therefore, it is not an easy task to select the right type of silicifying agent with good performance when processing test tubes. We need to comprehensively measure whether the silicifying agent has a positive impact on the test.   Water-soluble silicifying agent       2、 Favorable effects of silicifying agents       The wall of the silicified test tube will be very smooth. If you are not sure about the use effect, you can pour a small amount of water into the test tube and then pour it out. If there are no dispersed water droplets left on the inner wall of the silicified test tube, it will play a role. This provides convenience for later blood collection, and does not need to worry about the occurrence of blood cell wall hanging phenomenon, and lays the foundation for the extraction of high-quality serum. In addition, most manufacturers will require all test tubes to be silicified once before leaving the factory, which can prevent the occurrence of incomplete silicification or uneven distribution of additives, and ensure that the surface of the test tube has a protective film, which will not affect the blood test.       3、 Adverse effects of silicifying agents       When it comes to the adverse effects of silicifying agent, it mainly depends on its product quality. If the performance of the added silicified reagent product is poor, its pipe wall is not smooth enough, which will eventually lead to the phenomenon of blood hanging on the product after use, or other added reagents are attached to the pipe wall, which can not play a role, which will interfere with the test results and greatly affect the appearance, which is not conducive to purchase and use.       Desheng, as a supplier of silicified agents in China, its product types include water silicon and oil silicon. The stability of its performance and the simplicity of its preparation and operation are highly praised by customers. The company has set up a special quality control department to monitor and test the various indicators of the products at any time to ensure that customers are completely relieved to use them. If you have any intention, please click the website for consultation!
Latest company new about How to buy silicification agent for blood collection
2023/03/06

How to buy silicification agent for blood collection

How to buy silicification agent for blood collection        As a commonly used treatment reagent in test tubes, silicifying agent is particularly attractive in the market because of its role in promoting the smoothness of tube wall. Many manufacturers have also taken advantage of their product advantages to join in the production of silicifying agent. This is a good thing as well as a bad thing for buyers, which means that there are more opportunities to choose from, but the quality of products will vary and the price will vary. At this time, how to purchase silicified agent has become a headache, so I will introduce the precautions in the purchase process in detail for your reference.        1、 Silicifying agent manufacturer        Many people are willing to choose manufacturers to supply products in batches, which can not only ensure that the quality of products can be solved at the source, but also the price can be negotiated and adjusted. However, if you encounter "middlemen" who claim to be manufacturers, they mainly make profits and will not make profits on the price. This should be clear when you buy.        2、 Quality of silicifying agent        Product quality is an important factor to be considered in the purchase process. As a treatment reagent for blood collection, the requirements for silicifying agent are more strict. It must ensure stable performance, not easy to react with other additives, and the prepared water silicon solution should be transparent when sprayed into the test tube. Therefore, when purchasing, we should pay attention to it. We can ask for sample test first, and then choose to purchase if the test meets the requirements.        3、 Service standard        The price, quality and service are interlinked. The purchase of any product can not completely guarantee that there is no problem. The most important thing is to have perfect services, including pre-sale and after-sales services. Before sales, you can look at the consulting attitude, and after sales, you need to focus on the guarantee that the team can provide, such as whether the product is returned or replaced, so as to avoid the phenomenon that the quality problem of the goods cannot be solved.       4、 Supply of silicifying agent       Due to the different production cycles of different manufacturers, many businesses do not have stock or need to book in advance. In addition, the production equipment or process of some manufacturers cannot keep up, which will also lead to the shortage of goods. Therefore, you need to consult the delivery time and supply quantity in advance when purchasing. If it is in stock, you can choose the manufacturer to buy.       Desheng, as a Chinese manufacturer of silicified agent, has an independent warehouse and a professional R&D team. Its product types include water silicon and oil silicon, which are produced and sold by itself, and there is no price difference between middlemen. Moreover, the production of all batches of products is supervised by the quality control, so it can be purchased and used with complete confidence. If you are interested, please click the website for consultation!
Latest company new about What are the types of silicifying agents?
2023/03/01

What are the types of silicifying agents?

What are the types of silicifying agents?       As a necessary reagent for the treatment of vacuum tubes, silicifying agent can make the inner wall of vacuum tubes smoother and help improve the working efficiency. Some people will pay special attention to its performance and type when purchasing, because the difference of performance and type represents the use effect, and also has a close relationship with the price of the product. However, some people are not clear about this and cannot obtain more accurate quotations. So in order to avoid some unnecessary losses, we will introduce the types of silicified agents to you in detail, so as to facilitate the later selection and use.       1、 High-efficiency silicifying agent (oil silicon)       The appearance of high-efficiency silicifying agent is colorless to light yellow transparent liquid, and its main component is high molecular organic silicon material, which can be dissolved in organic solvents such as ethanol and petroleum ether, and it will hydrolyze and become gelatinous in case of water. The operation steps of adding into the test tube after preparation are simple. A protective film can be formed on both the glass surface and the plastic surface to make the tube wall smooth and transparent. Other additives or blood are not easy to produce wall hanging phenomenon.     oil silicon       Moreover, compared with other silicified agents, because of the high efficiency of addition and more stable performance, the cost control is more strict, which may make the selling price more expensive than other silicified agents, which needs to be understood.       2、 Water-soluble silicifying agent       Water-soluble silicifying agent is different from oil silicon. Its appearance is colorless and odorless transparent liquid, and its composition is high molecular methyl polysiloxane copolymer. It has hydrolysis stability and can be dissolved in water, ethanol and alcohol-water systems. At the same time, it can play a very stable role in the water solution with content less than 5%. However, it should be noted that if the acidity or alkalinity is too large, it may reduce the stability.       In addition, due to the use of non-ionic surfactants and silica powder in the process of use, it can not only ensure the activity of ingredients, but also effectively disperse blood and prevent hemolysis. Due to the low cost of control, the price is lower than that of silicone oil.       Whether using oil silicon or water silicon, the most important thing is to select the reagents that meet your own experimental requirements, so as to help the test results more accurate without deviation. Desheng, as a manufacturer of silicified agents in China, sells the two silicified agents mentioned above, and is tested and controlled by professional R&D personnel to ensure smooth use without other adverse effects. If you have relevant requirements, please click the website for consultation!
Latest company new about Lithium heparin price
2023/02/27

Lithium heparin price

Lithium heparin price       Heparin, as a substance naturally existing in the internal organs of animals, has been found to have strong anticoagulant effect in vivo and in vitro. According to this effect, heparin lithium was later made. Since the 1940s, it has been widely used in clinical medicine, such as anticoagulation of blood samples, preparation of drugs for antithrombotic treatment and use in major operations. These different fields of use lead to differences in production costs and ultimately in prices. So we will focus on analyzing the factors that affect the price of heparin lithium.       1、 Market demand       As the incidence rate of chronic diseases such as cardiovascular diseases is increasing year by year, the demand for anticoagulant drugs or anticoagulant reagents for some thrombotic diseases is increasing. In addition, the performance of heparin lithium can interfere with the coagulation process, which also drives the market of heparin lithium raw materials invisibly, making the price rise for a long time.       2、 Pig yield       Because heparin lithium contains "heparin", its extraction source is mostly from the intestinal mucosa of pigs. Although the pig industry is relatively developed, sometimes some uncontrollable factors will lead to a decline in production, which also has a significant impact on the extraction of heparin. For example, in the outbreak of swine plague in 2019, the extraction rate of heparin decreased, the production decreased, the market became scarce, and the natural price would fluctuate.       3、 Raw materials and process       It is not enough to make heparin lithium by extracting heparin. Usually, the product with pure color and no impurities is prepared, and the process and raw materials are also exquisite. For heparin lithium used in the medical industry, some manufacturers use imported raw materials, some manufacturers use domestic raw materials to save costs and the principle of simple process, which will lead to price differences in the finished products.       4、 Type       Due to the different types of heparin lithium, its price is also different. Just like refined heparin lithium and crude heparin lithium, refined heparin lithium is generally used in vacuum tubes for anticoagulation in vitro blood. This requires stable process and analytical purity of heparin, which requires high natural price. However, the crude heparin lithium is generally extracted and made through simple manufacturing steps. The requirements for various indicators are also relatively loose, and the natural price is also lower. These types of differences have become one of the factors affecting the price.       As a Chinese manufacturer of heparin lithium, Desheng has always pursued quality first, so it has set up a professional R&D and quality department to conduct repeated spot checks on batches of products to ensure customer satisfaction. If you are interested, please click the website to purchase!
Latest company new about Addition amount of heparin lithium
2023/02/23

Addition amount of heparin lithium

Addition amount of heparin lithium       In the emergency center, due to the rapid change of many patients' conditions and the uncertainty of the test time, it is easy to miss the best treatment opportunity and cause doctor-patient disputes. In recent years, with the development and popularization of test reagent products, such as EDTA potassium salt, heparin anticoagulant or coagulant, the efficiency of clinical testing has been effectively improved.       At present, most clinical biochemical tests use the changes of serum as a reference for diagnosis of diseases, but the traditional method of extracting serum is relatively slow. On the one hand, it is because of the slow blood coagulation, on the other hand, the residual fibrin in the serum after blood coagulation is easy to cause instrument blockage, affecting the whole analysis process.       Therefore, many hospitals have begun to use heparin lithium for anticoagulation. Compared with traditional methods, heparin lithium has a better effect on preventing blood coagulation, and the centrifugation speed is fast. All indicators are very close to the serological analysis indicators. However, some problems should be paid attention to in the overall use process, such as whether the addition amount and storage temperature of heparin lithium have any impact on other test items.       Precautions for use of heparin lithium anticoagulant:       1. It is generally recommended to add 15-25 IU of heparin lithium per milliliter of blood. If it is 20 IU/ml, it is better, but sometimes it will be added according to the experimental requirements, which is not a fixed dosage.       2. If the blood is to be fully anticoagulated, it should be noted that the test tube should be inverted more than 5 times as soon as possible after the blood collection, especially when the temperature of the blood collection environment is too high, it is easy to produce local coagulation and non-coagulation.       3. As a non-irreversible anticoagulant reagent, lithium heparin tube should complete the test as soon as possible after collecting blood samples, generally within 6 hours, otherwise it is easy to cause deviation in the test results.       4. If you want to extract high-quality samples quickly, it is recommended to use them together with the separation gel, which can not only play the role of separation and anticoagulation, but also more accurate for the test results, which is conducive to the analysis and judgment of medical staff.       As an old Chinese manufacturer specializing in the production of blood collection reagents, Desheng not only pursues the production quantity, but also focuses on the quality and service, and strives to provide high-quality products for the market and customers, and effectively enhance its brand influence. At present, in the domestic market, such as serum separation gel, EDTA potassium salt and heparin salt are hot products, so they are gradually sold abroad, and have reached cooperative relations with more than 100 foreign customers. If you have any purchase intention, please click the website for details!
Latest company new about Anticoagulant mechanism of heparin lithium
2023/02/22

Anticoagulant mechanism of heparin lithium

Anticoagulant mechanism of heparin lithium       As a widely used reagent in clinic, heparin lithium is mainly responsible for anticoagulation. Whether it is prepared into drugs or used as an additive for blood collection, it is achieved through blood, so many people are interested in its anticoagulation mechanism. In fact, to understand the anticoagulation mechanism, we need to understand why blood coagulates. Next, I will introduce it to you in detail.       1、 Blood coagulation principle       In life, we must all know that if you cut your finger and bleed, you just need to wipe it gently and stop it after a few minutes. In fact, this is the function of your own blood coagulation system. Because blood clots are formed at the bleeding site, there will be no continuous bleeding.       The essence of blood coagulation is the process of transforming soluble fibrinogen in blood into insoluble fibrinogen. In this process, the reason why heparin lithium can play an anticoagulant effect is to achieve the anticoagulant effect by inhibiting a certain link in the above coagulation process.       2、 Anticoagulant mechanism       When it comes to its anticoagulation mechanism, it basically relies on heparin to achieve its goal. Because it is strongly acidic and is a natural substance extracted from animal liver organs, its anticoagulation effect will generally include three aspects:       1. By increasing the function of antithrombin 3, which leads to the inactivation of thrombin, the purpose of anti-blood coagulation is achieved from the root.       2. After thrombin loses its activity, it further blocks blood coagulation by inhibiting platelet aggregation and adhesion.       3. Protein C is a key component of the body's blood coagulation system. Heparin lithium enhances the protein activity, thus stimulating the release of anticoagulant substances from vascular endothelial cells.       From the above introduction, we can know the anticoagulation mechanism of heparin lithium. When conducting medical tests, we recommend that you choose high-quality heparin products. Poor quality products may lead to poor anticoagulation effect. As a manufacturer specializing in the research and development of blood collection additives in China, Hubei New Desheng produces heparin lithium, which is a high-quality heparin of analytical purity. The unit packaging quantity can be divided into 10g/bottle and 50g/bottle. The quality requirements are immediately tracked and reported by the R&D personnel to ensure that customers can use it safely. If you have relevant requirements, please click the website for details!
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