China Wuhan Desheng Biochemical Technology Co., Ltd Company News

Crude heparin sodium CAS number and purpose   Heparin, as a naturally occurring substance, is mostly prepared into heparin sodium and used in medicine. However, in reality, it has many uses in addition to medicine, such as biochemical testing, blood collection and processing, or cosmetics. Most of the heparin sodium in these fields is purified and processed from crude heparin sodium to make high-quality heparin sodium for use. Below, we will focus on introducing crude heparin sodium to everyone.   heparin sodium powder     Crude heparin sodium CAS number   Firstly, let's understand what CAS number is. CAS number is a unique identifier for a chemical substance, assigned and managed by the International Chemical Registry (IUPAC). The CAS number is composed of numbers, representing the structure and composition of a compound, and can be used to identify and locate the compound globally. The CAS number of crude heparin sodium is 9041-08-1, which represents its composition and structure. As a mucopolysaccharide containing sulfate groups, it has strong negative charge biological activity and can be purified to prevent blood clotting.   Preparation of crude heparin sodium   1. Wash the fresh pig intestines (or naturally thawed pig intestines) with clean water to remove any debris, and then perform enzymatic hydrolysis.   2. Stir thoroughly, adjust the pH value with a small amount of alkaline solution, and maintain the solution temperature at 37-40 degrees Celsius to continue enzymatic hydrolysis for 3-4 hours.   3. Add a certain weight of refined salt, thoroughly mix it, and then heat it up for about 30 minutes. Fine filter and adjust the filtrate back to its pH range of 9.0-9.5 for ion exchange adsorption treatment.   4. After elution and filtration, combine the clear solution and filtrate, adjust the pH value again to an accuracy of 6.0-6.5, add measured ethanol to precipitate overnight, and carefully dry and suck out the upper clear solution, collect the lower sediment, and filter until dry. After vacuum drying, crude heparin sodium is prepared.   The use of crude heparin sodium   Usually, crude heparin sodium is used as the raw material for cosmetics. Due to its low production requirements and impurities, it is rarely used in the market, and its use is far less extensive and effective than high-quality heparin sodium. For example, refined heparin sodium can be added to the blood collection tube for use as an external Anticoagulant, or it can be prepared into an injection drug for use in the treatment of thrombotic diseases. The refined heparin sodium extracted from crude heparin sodium has high main content and few impurities, so it is more valued.   As a professional supplier of heparin sodium, Desheng's products are analytical pure, which are mainly used as Anticoagulant in blood collection vessels, with stable performance. To meet customer customization needs, the company can provide crude heparin sodium product services. If you have any relevant intentions, you can indicate your needs in advance and we are ready to answer you at any time.

Difference between heparin and heparin sodium   The anticoagulant heparin sodium, as a blood processing reagent, is highly valued in clinical practice due to its significant anticoagulant effect when in contact with blood samples. Although many people are proficient in its operating procedures, as a non irreversible anticoagulant reagent, attention should also be paid to the duration of action during use. Below, we will provide a detailed introduction around this point.   The mechanism of action of anticoagulant heparin sodium   Its mechanism of action is mainly through binding with coagulation factors II and VII in the blood, inhibiting the activity of coagulation factors, thereby preventing the formation of thrombin and achieving the goal of inhibiting blood coagulation. Because other factors have effects on the three stages of coagulation process, they have anticoagulant effects both in vivo and in vitro. In vivo, they mainly activate the endogenous fibrinolysis system, promote the dissolution of thrombus, and prevent thrombotic diseases.   The action time of heparin sodium   Heparin sodium can be classified into drug grade and analytical grade, and the duration of action of drug grade heparin sodium varies depending on individual differences, dosage, disease status, and other factors.   1. Drug grade heparin sodium: Generally speaking, its action time is about 2-3 hours, which is the time required for the drug concentration to decrease to half. In some special cases, such as prolonged use of heparin sodium during surgery, doctors will adjust the dosage and duration of medication according to the specific situation to achieve the best treatment effect.   2. Analysis of pure grade heparin sodium: It mainly acts in blood collection vessels. As anticoagulation is non irreversible, the heparin sodium anticoagulant tube should be tested within 6 hours after blood collection. This means that its action time is 6 hours, and if it exceeds 6 hours, there may be errors in the test results.    Precautions for using heparin sodium   1. When using the drug heparin sodium, in order to control the duration of the drug's action, it is necessary to adjust and monitor the dosage according to the specific situation of the patient. Before blood collection or transfusion, medical staff need to assess the patient's bleeding risk and coagulation function status, and provide appropriate doses of heparin sodium as needed.   2. When using the extracorporeal anticoagulant heparin sodium, it is necessary to ensure that the blood sample is fully anticoagulated. After blood collection, medical staff must quickly mix it upside down 5-8 times, especially when the blood collection temperature is high. If anticoagulation is not sufficient, it can easily lead to local coagulation.   3. Heparin anticoagulation is involved in the metabolism of cellular enzymes and ions, and its dosage can affect the detection results. Therefore, both in vivo and in vitro anticoagulation should pay attention to their respective dosage. For example, the recommended dosage range for blood sampling is 12-30IU of heparin sodium per milliliter of blood, and for micro blood sampling, anticoagulation can be less than 14IU. Only by using according to the standard can the safety and effectiveness of use be guaranteed.   As a professional manufacturer of heparin sodium, Desheng's products are all analytical grade raw materials, which are added to test tubes after preparation and are not related to drug grade heparin sodium. When purchasing, everyone needs to indicate their needs in advance so that customer service can better serve you. Welcome to contact us for purchase!

classification of heparin sodium       Heparin sodium, as a commonly used anticoagulant in clinical practice, can not only be added to blood collection vessels to prevent blood clotting, but also be prepared for drug use, effectively preventing thrombosis and reducing the occurrence of cardiovascular and cerebrovascular diseases. According to different preparation methods and structural characteristics, heparin sodium can be divided into various types. Next, we will introduce the classification of heparin sodium in detail.     heparin sodium powder   Classification according to preparation method   1. Natural heparin sodium: A natural product mainly extracted from animal organs such as pig intestines and cow lungs. After complete extraction of heparin, it is finely processed to obtain high-purity heparin sodium raw material. Its production requirements are strict, and it is usually added to the blood collection vessel for use, with relatively stable performance.   2. Synthetic heparin sodium: obtained through chemical synthesis, it has high yield and cost advantages. Currently, polymer method and metal organic compound method are mainly used in the market for synthesis, and its performance and usage are far inferior to the first naturally prepared heparin sodium.   Classification based on structural features   1. Ordinary heparin sodium: Ordinary heparin sodium is a high molecular weight heparin containing multiple repeating units, appearing in the form of a drug. Its anticoagulant effect is good, but its bioavailability is low, and it is prone to side effects. It is rarely used in clinical practice.   2. Low molecular weight heparin sodium: Low molecular weight heparin sodium is a short chain heparin obtained through chemical modification, with high bioavailability and suitable for intravenous injection. Due to its direct contact with the human body, it not only requires high production requirements and expensive prices, but also requires obtaining corresponding certificates before production, and is subject to the supervision of the Medical Commission.   3. Heparin sodium salt: This is a raw material of heparin sodium, mainly extracted from pig intestinal mucosa, and then obtained through ion exchange adsorption. Its average molecular weight is around 15000, and its potency is between 150IU-180IU. It is generally non injection grade, and is prepared into a solution and added to the blood collection vessel as an in vitro anticoagulant.   Classified by purpose   1. Medical heparin sodium: Medical heparin sodium includes the drug heparin sodium and the extracorporeal anticoagulant heparin sodium. Drug use mainly occurs in fields such as cardiac surgery, hemodialysis, and vascular intervention therapy, and has strong anticoagulant and therapeutic effects. The in vitro anticoagulant heparin sodium is mainly used in clinical practice to help blood clot quickly during blood collection and improve the efficiency of medical staff testing.   2. Industrial heparin sodium: This type of heparin sodium is generally low in purity, contains impurities, has low production requirements, and is cheap. It is mainly used in the manufacturing of industrial products such as cellulose and paper.   Different types of heparin sodium have different characteristics and application ranges, and selecting the appropriate type of heparin sodium needs to be considered based on the specific usage. As a professional manufacturer of heparin sodium, Desheng's product type is analytical grade heparin sodium salt, mainly used as an extracorporeal anticoagulant and cannot be used in the human body. If you are interested, you can indicate the usage requirements in advance for customer service to provide you with accurate quotations. Feel free to contact us at any time.

Blood anticoagulant heparin sodium cold store       Heparin sodium is prepared on the basis of heparin, which can be used as an extracorporeal blood anticoagulant to prevent blood clotting or as a commonly used anticoagulant to prevent and treat thrombotic diseases. Due to the different production processes and characteristics of drugs and blood anticoagulants, there are also differences in their storage methods during use. For example, heparin sodium injection and prepared anticoagulant heparin sodium solution have refrigeration conditions, while raw powder only needs to be stored at room temperature. Below, we will focus on the preservation of in vitro anticoagulant heparin sodium powder and solution.   Bottled heparin sodium       Preservation of heparin sodium raw material powder       From the appearance, the finished product is in powder form, and the powder is prone to moisture absorption. Therefore, its storage condition is that it does not need to be refrigerated, only needs to be sealed and stored at room temperature. It is required that the surrounding temperature change should not be too large, and it should not be exposed to sunlight.   Preservation of heparin sodium preparation solution       Compared to the original powder storage, the prepared solution has stricter storage conditions. Due to the solution's susceptibility to oxidation and heat, if left in the air for a long time, it can cause structural changes and reduce reaction performance. Therefore, it is necessary to use refrigeration to ensure the stability of the effect.       Refrigeration methods and precautions for heparin sodium solution       1. Storage temperature: The storage temperature of the solution should be controlled between 0-4 degrees Celsius to avoid excessive freezing or heating. When storing in the refrigerator, it should be placed in the freezer inside the refrigerator to avoid mixing with other products. In addition, it should be noted that the maximum storage period is one week and cannot be left for a long time.       2. Sealing requirements: The solution device should be well sealed to prevent air from entering. If it needs to be used, it should be checked for any leakage in advance. If there is any leakage or discoloration, it should be immediately stopped from use.       3. Usage: The solution is usually added to the test tube using both manual and machine methods. Before adding, the relevant instructions and instructions should be carefully reviewed, and the operation should be carried out according to the steps and specifications. Attention should be paid to cleaning various operating tools to avoid the infiltration of harmful impurities and affecting performance.       The original heparin sodium powder purchased can be stored at room temperature and away from light, but the prepared solution needs to be refrigerated and stored. This requires special attention to avoid performance changes caused by improper storage. As a manufacturer of heparin sodium raw materials, Desheng can provide customers with professional usage advice to ensure stable performance. If you have any interest, please click on the website to inquire and purchase!

Blood anticoagulant heparin sodium cas no       Heparin sodium, as an ideal anticoagulant reagent, has a CAS chemical number of 9041-08-1. Through this number, the product can be accurately located to prevent confusion, just like an ID card, and it can also help laboratory personnel quickly identify or query related chemical products. Below is a specific introduction to the relevant knowledge of heparin sodium chemical numbering.   Bottled heparin sodium   1、 The Meaning of CAS Number       CAS chemical number is the chemical substance registration number provided by the American Chemical Society, and is also a universal chemical substance identification system worldwide. Each compound has a unique CAS number for easy identification. It is composed of hyphens divided into three parts: the first part has 2-7 digits, the second part has 2 digits, and the third part has 1 digit as the verification code.       2、 The Naming Meaning of CAS Number       The naming significance of CAS numbers is closely related to their chemical structure. For example, for compounds containing multiple functional groups such as heparin sodium, heparin molecules contain sulfate and carboxyl groups. The naming significance of CAS numbers can be explained as peptide compounds containing sulfate and carboxyl groups. This naming method not only facilitates communication and research among chemists, but also provides important reference for the study of chemical structures.   3、 The significance of CAS number for heparin sodium       The CAS number of heparin sodium is 9041-08-1, which allows for a comprehensive understanding and study of the structure and properties of heparin sodium chemicals. At the same time, it is also clear what its uses are, such as being used in blood collection, as an extracorporeal blood anticoagulant, which can fully inhibit thrombin activity and prevent blood coagulation.       The chemical number of heparin sodium is of great significance, and now most people in the industry also use it to search for product information. In addition, it can help understand the chemical properties of heparin sodium and provide more reference value for practical applications.       As a professional manufacturer of heparin sodium, Desheng has a CAS chemical number of 9041-08-1. The finished product has a white powder appearance, which is convenient for transportation and storage. It is mainly added to test tubes for use as a blood anticoagulant, which is of great help in clinical blood processing. Due to the company's independent production, its supply capacity can reach tons, fully meeting customers' bulk order needs, and factory shipping, avoiding intermediaries, with favorable prices. If you are interested, please click on the website to inquire and purchase!  

Dfference between sodium heparin and lithium heparin   Heparin, as a natural anticoagulant substance, is extracted from pig intestinal mucosa and then chemically produced into heparin sodium or heparin lithium. Among them, they are most commonly used as in vitro anticoagulants when added to test tubes. Although their uses are consistent and the finished products are all white powder in appearance, it does not mean they are the same. Therefore, the following will introduce the differences between heparin sodium and heparin lithium in detail.   Bottled heparin sodium   1、 The difference between the two binding ions   Although they all exist in the form of heparin, there are obvious differences in ionic structure, which makes heparin sodium and heparin lithium almost identical in appearance, but fundamentally different. In addition, different binding ions represent different degrees of dissociation, and the heparin lithium produced by Desheng is obtained by replacing it with heparin sodium.   2、 The dosage of heparin sodium and heparin lithium is different   They can be added to vacuum blood vessels as anticoagulants, but they need to be added according to industry standards after being prepared into a solution, and the dosage of the two is different. The standard dosage range for heparin sodium in the industry is 9.41-281U units/milliliter, while the additive amount for heparin sodium is 121U-301U per milliliter of blood.   3、 Differences in white blood cell count results in biochemical testing   In the routine test report, it can be intuitively seen that heparin sodium and heparin lithium have different white blood cell count results for the same sample. The manifestation pattern of heparin sodium is more obvious, and it can change over time. For example, over time, the white blood cell count increases at a constant temperature and then decreases. However, the decrease in white blood cell count detected by heparin lithium is not significant, and the entire process changes slowly and steadily.   Bottled heparin lithium   4、 The prices of heparin sodium and heparin lithium are different   You can find that the prices of heparin sodium and heparin lithium are different when purchasing online or looking for manufacturers to supply, with heparin lithium being more expensive than heparin sodium. This is mainly because on the one hand, heparin lithium is replaced from heparin sodium, and on the other hand, heparin lithium has the least interference with certain experiments.   The difference between heparin sodium and heparin lithium can be clearly seen from the above four aspects, and everyone should pay attention to distinguishing when using them. In addition to heparin sodium and heparin lithium, commonly used anticoagulants include EDTA potassium salt, sodium citrate, etc. Desheng, as a professional manufacturer of raw materials for blood sampling additives, is involved in all the aforementioned products. In addition, it also sells flagship products such as biological buffering agents and luminescent reagents. If you are interested, please click on the website to inquire and purchase!

Adding and Using EDTA Dipotassium Salt       Blood testing is a routine examination in clinical medicine, and the vast majority of outpatient or physical examination personnel undergo this examination one by one. In order to ensure the accuracy of the examination results, manual testing has gradually developed from the beginning to fully automated testing. Ethylenediamine dipotassium salt, as a blood processing reagent, has significant anticoagulant effects and minimal impact on blood cell morphology. Therefore, it has become one of the highly respected and popular reagents in blood analysis. Next, we will introduce it in detail.       1、 Color of Ethylenediamine Dipotassium Salt Test Tube       The color of the test tube containing ethylenediamine dipotassium salt is purple. As an additive to prevent blood coagulation, it is generally called EDTA salt or ethylenediamine tetraacetic acid salt. Although ethylenediamine dipotassium salt can be added to purple test tubes, it should be noted that sometimes it may not be added to the purple tube, but it may also be ethylenediamine disodium salt. These two types of EDTA salts belong to the same category, and the purple tube can contain any of them. When used, it is usually distinguished based on the test tube label and testing items.   EDTA K2 Powder       2、 The effect of ethylenediamine dipotassium salt on blood       The effect on blood in test tubes is mainly reflected in its ability to fully protect blood cell components without affecting white blood cell count and size, and has a small impact on red blood cell morphology. At the same time, it can inhibit platelet aggregation, making it very suitable for general blood routine testing. However, it should be noted that ethylenediamine dipotassium salt test tubes cannot be used for coagulation experiments or platelet function tests, and should be inverted and mixed as soon as possible after blood collection to ensure sufficient anticoagulation.       3、 Addition and Use of Ethylenediamine Dipotassium Salt        The form of ethylenediamine dipotassium salt added to the blood collection vessel is a prepared aqueous solution. Generally, 4 milligrams of ethylenediamine dipotassium salt are required to anticoagulate 2 milliliters of blood. However, due to the low concentration, in order not to dilute the blood, a 200g/L aqueous solution containing ethylenediamine dipotassium salt is usually pre placed in each blood collection vessel μ。 At the same time, it is important to pay attention to the expiration date and usage environment during use. If there are changes in the usage environment, such as high or low temperatures, water can easily evaporate on the tube wall, especially plastic test tubes that may leak out of the tube wall and cause crystallization inside the tube. Therefore, it is necessary to mix them upside down during blood collection.       As a raw material supplier for blood vessel additives, Desheng has dedicated personnel to supervise and control every step from production to shipment. Not only does the product quality meet standards, but its performance is stable and does not interfere with any experimental results. If you are interested, please click on the website to inquire and purchase!

Do you centrifuge sodium heparin tubes?       In clinical biochemical testing, most analysis relies on serum or plasma samples, but the whole blood is extracted from the human body, making it difficult and time-consuming to prepare complete serum or plasma samples. In order to solve this problem, reagents such as EDTA potassium salt, heparin sodium, and serum separation gel have emerged in the domestic market to help improve efficiency. Under the treatment of these reagents, blood samples can also be quickly prepared into stable specimens by centrifugation, thus achieving detection purposes. The use of heparin sodium test tubes is relatively common, but there is also great controversy. Some people believe that it does not need centrifugation, while others believe that it should be centrifuged. So, does it really need to be centrifuged? Below is a specific analysis for everyone.   Bottled heparin sodium       The anticoagulant effect of heparin sodium in blood vessels       Because it is a natural anticoagulant substance extracted from animal liver organs, it can bind with antithrombin 3 to cause structural changes. After its activity is activated, it binds to coagulation factors, thereby inhibiting the action of coagulation factors, leading to weakened thrombin reaction and prolonged coagulation time. In blood collection, it plays a role in preventing coagulation of blood samples, which can provide convenience for the biochemical testing items that need to be carried out.       Is the heparin sodium test tube centrifuged       In blood collection, it plays a role in preventing blood clotting, but cannot extract the required serum or plasma samples, so centrifugation is required. Only by centrifugation can the blood sample be completely separated, and then the centrifuged sample is used for testing to obtain accurate results. There are many cellular components in whole blood, and there are also differences in the testing items. If centrifugation is not carried out, it may lead to difficulties in conducting experiments, such as the blockage of analytical instruments due to the presence of fibrin in serum.       Items for heparin sodium test tube testing       1. Routine blood testing: Due to its strong physicochemical properties and physiological inertness, it does not affect blood composition and is less prone to hemolysis on red blood cells, so it is often used in routine sample analysis.       2. Liver function test: It can prevent blood clotting, so it is suitable for checking liver and kidney function, such as detecting fatty liver, hepatitis, etc.       3. Blood gas and erythrocyte sedimentation rate detection: Due to its interference with coagulation, it can have the effect of antithrombin. After the coagulation time of the sample is extended, it can be applied to blood gas analysis and erythrocyte sedimentation rate examination.       As a raw material manufacturer for blood collection additives, Desheng produces all products with analytical purity and stable performance. If you have high requirements for blood samples and want to quickly centrifuge, you can choose our serum separation gel to complete. Interested parties are welcome to click on the website to inquire about details!

Effect, dosage, and preservation method of dipotassium edta anticoagulant       Ethylenediaminetetraacetic acid dipotassium CAS is 25102-12-9, which is a recommended treatment reagent by the International Committee on Hematology. It not only has good anticoagulant effects, but also has little impact on blood cell composition, ensuring that the morphology of red blood cells, white blood cells, and platelets does not change, and has strong stability. Based on these obvious advantages, it has become an indispensable processing reagent in clinical medicine. Below, we will introduce it in detail.       1、 The effect of potassium ethylenediaminetetraacetic acid anticoagulant   As a calcium chelating agent, due to the presence of calcium ions in the blood, it can chelate with calcium ions. This decrease in calcium ion content will prevent endogenous or exogenous coagulation processes, thereby achieving the goal of anti blood coagulation. It is suitable for various biochemical tests. But precisely because of its anticoagulant effect, it cannot be used for the determination of metal substances in plasma and coagulation experiments, otherwise the accuracy of the experimental results cannot be guaranteed.   EDTA K2 Powder       2、 Concentration addition of potassium ethylenediaminetetraacetic acid anticoagulant       Although blood collection vessels containing potassium ethylenediaminetetraacetate are currently widely used, the amount of concentration added remains a problem. It is generally recommended to collect 0.5-2ml of blood in test tubes, but in the actual blood collection process in hospitals, it may sometimes exceed the standard blood collection range, which may lead to an imbalance in the ratio of blood samples to potassium ethylenediamine tetraacetate anticoagulant, leading to slight coagulation of the sample, instrument blockage, or inaccurate analysis results. Therefore, in response to this phenomenon, relevant researchers have provided the most appropriate standard concentration range of potassium ethylenediaminetetraacetate at 2.24mg/mL.       3、 Preservation of potassium ethylenediaminetetraacetic acid anticoagulant       The finished product of potassium ethylenediaminetetraacetic acid sold as powder is easily affected by moisture when dissolved in water, so its storage method and quality are closely related. If it is necessary to prepare it into a solution, be sure to immediately remove and seal it, and do not place it in an excessively humid environment. If the solution is in a prepared state, it needs to be stored in a high-density glass bottle to ensure that the storage device is free of impurities, reduce the possibility of reaction between potassium ethylenediaminetetraacetate and other substances, and pay attention to the surrounding environment being dry and the temperature not being too high.       As an advantageous manufacturer of potassium ethylenediaminetetraacetic acid anticoagulant, Desheng has clear specifications for its key indicators such as pH value, solubility, molecular weight, and stable quality, which can be used by customers to complete different experiments. At the same time, there are a large number of spot goods for sale in the warehouse, and there is no shortage of goods, so there is no worry about use. If you are interested, please click on the website to inquire and purchase!  

what is heparin sodium used for       When conducting blood sampling tests in hospitals, test tubes containing heparin sodium are often used. Due to their anticoagulant properties, blood samples can be specially processed, and can provide effective reference value for disease diagnosis and pathological analysis. Therefore, they are often used in routine biochemical testing projects. Insiders can tell at a glance what heparin sodium is used for, but laypeople may not have a deep understanding of it. Therefore, let me give you a specific scientific popularization of what heparin sodium is used for?       The principle of heparin sodium       In fact, to know exactly what it is used for, one must know its mechanism of action from the source. Due to its unique properties, it can fundamentally inhibit the activity of coagulation factors by binding to them, thereby inhibiting the formation of thrombin, prolonging the process of transforming soluble fibrinogen into insoluble fibrinogen, and fully inhibiting platelet aggregation to achieve anticoagulant effects.   Bottled heparin sodium       The effect of heparin sodium       According to the wide range of application fields, it can be classified and applied in various aspects:       1. Blood collection anticoagulant       Based on its mechanism, it can be known that it has the effect of preventing blood clotting, and because it is of analytical purity, it is often added to blood collection vessels to have an anticoagulant effect on blood samples. Due to its good anticoagulant effect and effective guarantee of the stability of serum and plasma components, it has been highly valued in clinical practice, so its appearance is mostly in the form of blood collection additives.       2. Medicinal heparin sodium       This is also used in drugs based on the principle of anticoagulation, but its production requirements are very strict, and there are few manufacturers that can meet the standards. Generally, it is made into drugs that can effectively prevent large coagulation diseases such as thrombosis and myocardial infarction by taking or injecting them into the human body. At the same time, it can also be used as a drug for hemodialysis or thrombolytic therapy to reduce the possibility of complications.       3. Daily chemical heparin sodium       It is mainly used in cosmetics or skin care products, such as nutrition cream, eye cream, acne removal and other products, which can significantly improve the Vascular permeability of the skin, while improving the blood circulation of the skin, improving local circulation, ensuring that the skin can obtain nutrients and promote the excretion of metabolites.       According to the properties of heparin sodium, it can be added to blood vessels, made into drugs, or added to cosmetics. It has many uses, so the quality requirements for heparin sodium raw materials are very strict. As a manufacturer of heparin sodium raw materials, Desheng can provide analytical grade heparin sodium for anticoagulant use in blood collection. If you have any needs, please click on the website to inquire and purchase!

heparin sodium classification       Heparin, as a naturally occurring substance in animal liver, has been found to have anticoagulant effects. Therefore, many manufacturers have prepared heparin sodium or heparin lithium raw materials based on it for use in vacuum tubes. But they don't just have one function, they can be applied to different aspects through different categories, and their categories and prices also vary. Many people increase their purchasing costs because they don't know the classification, which sometimes brings a lot of trouble for experiments. So in response to this situation, let's take heparin sodium as an example and introduce the classification in detail. Later on, we can also differentiate and purchase.   Bottled heparin sodium       1、 Analytical grade heparin sodium       The main source of its extraction is pig small intestine mucosa, but the production process is fine, with strict numerical requirements. The finished product is a white powder, easy to dissolve in water, with an average molecular weight of around 15000 and a potency between 150IU-180IU. It is formulated as a solvent and added to vacuum blood collection vessels to have an anticoagulant effect on blood.       2、 Low molecular weight heparin sodium       It is mainly used for medical injection into the human body, and its production requirements are generally stricter than other types of heparin sodium, and its price is expensive. It can be used to treat large diseases such as thrombosis in the human body. Although it is also composed of a mixture of polysaccharide chains, its average molecular weight is between 4000 and 5000, which is much lower than the analysis of pure heparin sodium. It also has strong anticoagulant effects and has fewer complications in clinical treatment of thrombosis.       3、 Cosmetic grade heparin sodium       This is a raw material in cosmetics, which is usually added to the skin care products of redness, swelling and acne gel. The addition amount is about 0.6%, which can use its anticoagulation, thrombosis and blood viscosity reduction effects to improve the skin permeability, improve the local skin blood circulation, and is conducive to the nutrition supplement of the skin, which has a good maintenance effect.       There are roughly three categories of heparin sodium mentioned above. There are differences in the production processes and requirements of these three types, and their prices also vary. Please choose according to your own usage. As a professional manufacturer of heparin sodium, Desheng sells heparin sodium products that are analytical pure for external use and cannot be directly used in the human body. When purchasing, users can express their purpose clearly, which is convenient for customer service to provide accurate answers. If you have any purchasing intentions, please click on the website to inquire about the details!

Preparation Steps and Extraction Methods of Heparin Sodium Porcine       Heparin sodium, as an anticoagulant reagent, is usually added to vacuum tubes for medical staff to use. Currently, the most widely sourced source of heparin sodium on the market is extracted from the intestinal mucosa of healthy pigs. However, due to the large amount of impurities and bacteria in the heparin sodium directly extracted from pig mucosa, it requires manual separation and preparation to obtain high-quality heparin sodium raw materials.       China has a vast territory, a large-scale animal husbandry industry, and abundant pig resources, making it a major country in extracting heparin. Nowadays, most domestic manufacturers also extract crude products from pig intestines and make them into high-quality products for sale. Although the extraction methods are unified, there are still differences in their respective preparation methods. Below, we will discuss in detail how to prepare heparin sodium extracted from pig mucosa?       Steps for extracting heparin from live pigs      1. Bowel washing: Clean the feces inside the intestine, and then soak the pig intestines filled with water in water for a day. If the temperature is too high in summer, add ice to the soaked water.       2. Intestinal scraping: Generally, a scraping machine is used to operate. The soaked pig intestines are placed in the scraping machine, and the mucosal surface of the intestine is scraped. Then, the casing is scraped to obtain a complete and undamaged casing.       3. Irrigation: Rinse the scraped casing with clean water, remove any impurities left during the scraping process, and then check if the casing is damaged or spoiled.       4. Salt pickling: Spread the casing evenly, fully apply the specialized salt required for production to each part, marinate for one day, repeat the operation the next day, then put it into a tank to drain the salt water, and then refrigerate at low temperature to prevent spoilage.   Heparin sodium powder       Extraction method of crude heparin sodium       1. Resin treatment: Pour a certain amount of heparin sodium specific resin into the cylinder, wash off impurities adhered to the surface of heparin sodium with water, and then remove water before pouring it into alcohol and letting it stand overnight. Then remove the alcohol and pour it into 40 degree hot water to wash away the remaining alcohol smell in the cylinder. Soak it in a calculated hydrochloric acid solution and stir repeatedly during this process.       2. Salt hydrolysis: Put the scraped casing into the mixing tube, add water and specialized salt for casing processing, stir thoroughly, and then add alkaline substances to adjust the pH value, heat up and filter.       3. Adsorption: Pour the pre processed heparin sodium resin into the adsorption tank and stir, accurately control the concentration of the adsorbed solution, and use a filter screen to remove the heparin sodium resin.       4. Washing: Wash with professional processed salt from the casing, stir the heparin sodium resin twice at intervals, pour the washing solution, and wash away any interfering substances adsorbed in the resin.       5. Precipitation drying: After washing, add alcohol and stir, cover and seal, and then place in a low-temperature refrigeration room to precipitate for 24 hours. Collect the paste heparin, and then use the precipitate to load a plate and dry it in a 60 degree drying oven for 3 hours to obtain the crude heparin sodium.       After the above steps, crude heparin sodium can be obtained, and on top of it, refined heparin sodium can be prepared for use. As a professional manufacturer of heparin sodium, Desheng takes every step to extract heparin from pig intestines and manually prepare it, providing customers with on-site inspection opportunities. If you are interested, please click on the website for consultation!