Analysis of raw materials for anticoagulant heparin sodium for blood collection

With the continuous development of medical technology, the collection and analysis of blood samples play a crucial role in clinical diagnosis and treatment. Heparin sodium, a blood vessel anticoagulant, plays an indispensable role in clinical blood testing. It can anticoagulate blood samples for a short period of time, ensuring that a series of tests are carried out in an orderly manner and providing effective basis for test results. This article will introduce the synthetic raw materials and basic information of heparin sodium anticoagulants.

Raw materials for heparin sodium

Heparin sodium is a natural biopolymer substance. The main components of heparin sodium as a blood vessel additive are lung adenosine, mucopolysaccharide, gelatin, and adenosine. Among them, lung adenosine is the main raw material of heparin sodium, accounting for more than 60% of the finished product of heparin sodium. Lung adenosine is a polymer extracted from animal tissues, and pig lung adenosine is currently the main raw material used in the production of heparin sodium. The additive heparin sodium for blood collection mainly comes from animal liver, especially pig liver.

In fact, there is also heparin in the human body, but it exists in the form of ions in the blood. It is an important anticoagulant substance in the human body that can effectively prevent blood clotting and thrombosis. It is one of the important factors for maintaining normal blood flow and circulation.

Preparation of heparin sodium

The production process of heparin sodium is divided into steps such as raw material preparation, extraction, refinement, synthesis, and purification. The specific steps are as follows:

1. Preparation of raw materials: Mix pig lung adenosine, mucopolysaccharide, gelatin, and adenosine in a certain proportion to prepare them as raw materials for heparin sodium.

2. Extraction: Add the mixed raw materials to the acid solution and hydrolyze under high temperature and pressure to produce heparin polysaccharides.

3. Refinement: Further purification and separation of heparin polysaccharides are carried out using processes such as precipitation, filtration, and purification.

4. Synthesis: The refined heparin polysaccharide is subjected to a series of chemical reactions to synthesize high-purity heparin sodium.

5. Purification: The synthesized heparin sodium is subjected to final purification treatment to remove harmful ingredients and impurities, and is powdered for easy use and storage.

6. Quality control: Conduct strict quality control to ensure that the quality of the product meets the final requirements.

Advantages of heparin sodium

1. Significant anticoagulant effect: Heparin is an efficient anticoagulant that can effectively inhibit blood coagulation and prevent thrombosis.

2. Low interference with blood cells: Heparin has little interference with blood cells, does not affect the size and morphology of red blood cells, does not cause hemolysis, and is suitable for various blood tests.

3. Convenient storage: Heparin anticoagulants can be stored at room temperature without the need for refrigeration, making them more convenient to use and store.

4. Safe and reliable: Heparin has high safety and reliability in clinical application, and the risk of allergic reactions is low.

Application of Heparin Sodium

The previous text introduced many advantages of heparin sodium, so it is often used in the detection of whole blood samples. In addition to being used in blood testing, heparin is suitable for red blood cell fragility testing, blood gas analysis, hematocrit testing, hemorheology, and emergency biochemical testing. Heparin sodium anticoagulants are often used in the detection of pH, blood gas, electrolytes, and calcium ions.

Hubei Xindesheng Material Technology Co., Ltd. is a manufacturer of a complete set of blood vessel additives. Currently, its products include heparin sodium, heparin lithium, serum separation gel, etc. Widely used, with a complete range of products, it can meet the one-stop shopping needs. If you need to make a purchase, please feel free to inquire and order!