Application of sodium fluoride EDTA potassium anticoagulant in blood glucose detection

Blood glucose detection should be familiar to all of us. It is a common project in the hospital. Blood glucose detection mainly depends on whether there is a rise in blood glucose, diabetes, and the severity of diabetes. In the process of blood glucose detection, appropriate anticoagulants must be selected to reduce errors, improve accuracy, and provide accurate diagnosis basis for clinic.

With the popularity of disposable vacuum blood collection vessel in China, blood glucose anticoagulant tube (containing sodium fluoride potassium oxalate) has been widely used, and greatly improved the quality of blood glucose samples and the accuracy of results. In practical work, the anticoagulant can be used to prepare blood glucose test samples with good preservation effect.

Sodium fluoride is a kind of weak effect anticoagulant. Its melting point is more than 990 ~ C. the anticoagulant tube can be dried at 100 ℃. It can effectively inhibit the enolase in the process of glycolysis, block the dehydration of monophosphoglyceric acid produced in the third stage of glycolysis pathway, lead to the energy redistribution within the molecule, and ultimately can not form high-energy phosphoenolpyruvate, so as to achieve effective inhibition of glycolysis and maintain the relative stability of blood glucose concentration, so it is considered to be an excellent method for blood glucose detection Good preservative.

Additives for blood collection vessels produced by Desheng

Potassium oxalate can combine with calcium ions in blood to form insoluble calcium oxalate precipitation, thus preventing blood coagulation. But in the process of preparing anticoagulant tube, it can only be dried below 80 ~ C. If the temperature exceeds 80 ℃, carbon monoxide and potassium carbonate can be decomposed into anticoagulant.

EDTA dipotassium can chelate with calcium ion in blood to prevent blood coagulation, and has fast dissolution and good anticoagulant effect. In the process of preparing the anticoagulant tube, it can be dried at 100 ℃ just like sodium fluoride, and the anticoagulant effect can still be maintained without being decomposed. Compared with potassium oxalate, it is easier to produce and improve the efficiency.

Desheng is an old brand manufacturer in the field of vascular additive. Its main products are: dipotassium EDTA, Tripotassium EDTA, coagulant, blood separation gel, potassium oxalate, sodium fluoride, etc., which enjoy a high reputation both at home and abroad. Desheng has always put "customer first, symbiosis and win-win" in the first place of service, so that enterprises ordering Desheng vascular additives can have a more perfect after-sales service experience.