Carbomer 940, like 980, is one of the most commonly used carbomer gels. Its chemical structural formula is an acrylic polymer cross-linked with polypropylene ether. It has strong hygroscopicity and becomes weakly acidic after neutralization. Forming a high-transparency gel, it is used in pharmaceutical excipients in addition to the skin care products most commonly used.
Note: Carbomer used in pharmaceutical excipients does not have sterilization and disinfection effect:
Carbomer has many examples of application in pharmaceutical excipients, such as the currently used no-clean disinfectant gel, carbomer eye drops, carbomer intracavitary adhesive preparations, bioadhesives, cards Pom skin antiseptic gel, etc. It should be noted that carbomer is used as a pharmaceutical excipient and does not have a sterilizing effect. It is only used as a carrier medium for drugs, such as gels, thickeners, dispersants or suspending agents. It does not have the effect of other drugs, but it has no toxic effect on the body or skin without impurities, which is why it can be widely used in cosmetics.
Carbomer and its gel
Carbomer 940's performance difference with other gels when used in pharmaceutical excipients:
Different carbomers have different performances in pharmaceutical excipients. Carbomer 940 is also the same. After carbomer gel is made, the adhesion of 940 is lower than that of carbomer 934 or 934P, so it is given in some cavity The drug system needs to increase adhesion and prolong the drug release time. Instead of 940, use 934P or 934 with stronger adhesion.
When preparing a water-soluble gel, the amount of carbomer used is 0.5%-2% according to the viscosity of the desired gel. When preparing an emulsion gel, the concentration is 1%. In terms of gel transparency and thickening rate, the Carbomer 940 effect is significantly better. Carbomer 940 is used as an auxiliary material for external medicine, easy to apply, and can absorb tissue solution, which is conducive to discharge of secretions, good stability, smooth and comfortable skin feel, easy to clean and good breathability. Some oral medicines are made into gels for transdermal administration, which are used as external medicines, reducing the irritation of internal organs. Carbomer also has moisturizing properties when applied to skin externally, it can lubricate the skin, protect the skin from pollution and irritation, and has an anti-infective effect.
At present, due to the severely limited supply of imported carbomer raw materials in China, it is almost interrupted. Domestic high-quality carbomers are in short supply. The same is true of Desheng's carbomers. Now the factory has added a large number of equipment and the carbomers production capacity has been further upgraded. .
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