Did you choose the right sodium citrate for the pharmaceutical industry?

Did you choose the right sodium citrate for the pharmaceutical industry?

Sodium citrate is a widely used chemical additive in food, medical and chemical industries. Widely used in medicine and other industries. However, for some people who are new to this product, they are not clear about the requirements of sodium citrate in different application fields. For example, recently we have contacted a purchaser from a daily chemical product factory. The sodium citrate he needs and the trisodium citrate dihydrate we use as an anticoagulant in blood collection tubes are completely different products and cannot be replaced by each other.

Sodium citrate is usually referred to as trisodium citrate. The full name is actually called trisodium citrate dihydrate. The molecular formula is Na3C6H5O7.2H2O. This substance is widely used in food additives, emulsification enhancers and the pharmaceutical industry. Colorless crystals or white crystalline powders, taste salty, and have a unique cooling sensation. In addition to trisodium citrate dihydrate, there is also trisodium citrate pentahydrate with the molecular formula Na3C6H5O7·5.5H2O. The difference is only the number of crystal water.

Sodium citrate is often used as an anticoagulant in medical and health care. Sodium citrate can form difficult-to-dissociate complexes with calcium ions in the blood to prevent calcium ions from participating in the coagulation process. This is the main product of Desheng Biochemical Sodium Citrate field. Like EDTA Na2 and potassium oxalate, it is a good coagulant in blood collection tube additives. In clinical collection of fresh blood, it is necessary to add a certain amount of sterilized sodium citrate as an anticoagulant. The citric acid generated by the ionization of sodium citrate can combine with calcium ions in the blood to form complexes that are difficult to ionize, thereby inhibiting The coagulation of blood, so sodium citrate is called an anticoagulant. It can also be used as a diuretic and phlegm-reducing medicine.

Sodium citrate has many excellent properties: such as safety and non-toxicity, biodegradability, strong complexing power for metal ions, excellent solubility, and good pH adjustment ability. It should be noted in the pharmaceutical industry that citrate ions and calcium ions can form a soluble complex that is difficult to dissociate, thus reducing the concentration of calcium ions in the blood and hindering blood coagulation. This product is used as an in vitro anticoagulant during blood transfusion or laboratory blood sample anticoagulation. In the formation of prothrombin activator and the subsequent clotting process, calcium ions must be involved.

Desheng Biochemical has specialized in the production of sodium citrate since 2005. I would like to remind you that sodium citrate has a wide range of uses, including analytical grade, industrial grade and medical grade. According to the needs of special industries, special attention should be paid to the purity, the content of crystal water, and the packaging and storage methods. If you have any questions about the use of the product, please contact Desheng Biochemical for consultation.