Differences in blood anticoagulants lithium heparin and sodium heparin

Heparin is a commonly used anticoagulant, widely used in clinical medicine and biochemical experiments. Among them, heparin lithium and heparin sodium are the two most common heparin anticoagulants, with slight differences in structure and application. The following will compare and analyze these two types of heparin anticoagulants to help them better use.

1. Structural differences: Although both heparin lithium and heparin sodium can anticoagulate blood, there are differences in chemical structure and effective binding ions, resulting in differences in dissociation degree. Our company's heparin lithium is replaced from heparin sodium.

2. Anticoagulant activity: There is no significant difference in anticoagulant activity between heparin lithium and heparin sodium. Both can effectively inhibit the activity of thrombin, block the coagulation process, and thus have an anticoagulant effect. In clinical use and biochemical experiments, the two can usually replace each other.

3. Application field: Heparin lithium and heparin sodium are widely used in different fields. In addition to being able to perform in vitro anticoagulation, heparin lithium is also commonly used in fields such as cardiac surgery, hemodialysis, intravenous infusion, and venous catheterization. Heparin sodium, on the other hand, mainly appears in the form of anticoagulants for blood collection, protecting the cells and proteins in the blood collection sample from interference from coagulation and maintaining the original characteristics of the sample.

4. Storage stability and usage: Lithium heparin and sodium heparin have their own advantages in terms of storage stability. As long as stored in dry and dark conditions, they can maintain their anticoagulant activity for a long time. In addition, special attention should be paid to its dosage and usage method. Excessive use may lead to poor anticoagulation effect, and industry standard dosage should be followed. The dosage range of heparin lithium in the industry standard is 9.41-281U units/ml, while heparin sodium is 121U-301U per milliliter of blood.

Heparin lithium and heparin sodium are common heparin anticoagulants, although they are both anticoagulants, there are also differences. When using them, it is necessary to choose appropriate anticoagulants based on the specific situation, and pay attention to their storage stability and dosage to ensure safe and effective application in clinical and experimental settings. As a manufacturer of blood collection additives, Desheng can provide high-quality heparin sodium and heparin lithium, but both are analytical grade and added to test tubes for in vitro anticoagulation use. It cannot be used as a drug. This needs to be understood clearly. Welcome interested parties to contact us anytime to purchase!