Heparin sodium is a commonly used chemical substance with a wide range of applications. It can not only be used as a drug in vivo, but also can be used as a blood Anticoagulant in vitro, mainly by inhibiting the activity of thrombin and other coagulation factors to prevent blood coagulation. Below is a detailed introduction to the main functions and application fields of heparin sodium.
1、 Anticoagulant effect
Heparin sodium enhances its activity by binding to antithrombin III, thereby inhibiting the formation of thrombin, which can prevent the formation of blood clots. In addition, heparin sodium can further enhance its anticoagulant effect by inhibiting the activity of other coagulation factors, such as thrombin factor Xa.
2、 Blood collection and processing
After being configured as a solution, it is mainly added to a vacuum test tube. When in contact with blood samples, it can inhibit blood coagulation in the test tube, thereby ensuring the stability of the blood collection environment and improving the collection and processing efficiency of medical staff. It generally does not come into direct contact with the human body and will not have any side effects on the human body.
3、 Prevention and treatment of venous thromboembolism
Venous thromboembolism is a serious thrombotic disease, including Deep vein thrombosis (DVT) and Pulmonary embolism (PE). Heparin sodium injection can be used to prevent and treat these conditions, especially in surgery, prolonged bed rest, and high-risk patients. It usually comes into contact with the human body, and its level and purity requirements are high. Generally, manufacturers without qualification certificates are not allowed to produce and sell it.
4、 Hemodialysis and cardiac surgery
Heparin sodium is also commonly used in hemodialysis as a Anticoagulant to prevent thrombosis in dialysis devices and blood vessels. The Anticoagulant during dialysis needs to maintain appropriate anticoagulant effect to ensure the normal circulation and filtration of blood in the dialyzer. In cardiac surgery, heparin sodium is commonly used as anticoagulant therapy to prevent the formation of blood clots during and after surgery. It is usually used in combination with other Anticoagulant (such as Warfarin) to achieve better anticoagulant effect.
5、 Other application areas
Heparin sodium can also be added to daily chemicals to have antioxidant, anti-inflammatory, and promoting blood circulation effects. At the same time, it can not only protect the skin from damage, slow down skin aging, but also reduce skin redness, swelling, inflammation, and increase skin metabolism, thereby improving the poor condition of the skin.
Heparin sodium, as an important anticoagulant, has a wide range of applications. Its anticoagulant effect is achieved by inhibiting the activity of thrombin and other coagulation factors. However, when using, it is also important to pay attention to the amount of addition, and not too much or too little, otherwise it will cause changes in the results. As a professional supplier of heparin sodium, Desheng mainly provides blood collection additives and uses in vitro anticoagulant reagents. If you have any raw material requirements, please feel free to contact us for purchase!
