Will blood sampling additives affect test results?
With the advancement of medical development, clinical testing technology has also been improved, and the corresponding biochemical testing index requirements have become strict. As an important reagent in testing, the appearance of blood sampling additives has effectively improved the overall testing level. Currently, the additives for blood sampling appearing on the market include various categories, such as serum separation gel, heparin sodium, heparin lithium, EDTA dipotassium, tripootassium, disodium, coagulant enhancer, silicifying agent, etc. Do so many additives have any impact on the test results? Let's focus on this aspect and introduce it to you.
In fact, whether additives have an impact on the test results is related to their performance and use:
In a test tube, it can achieve rapid turnover with the aid of a centrifuge, separating serum from blood cells, not only ensuring the stability of serum chemical components, but also facilitating the effective extraction of high-quality serum samples by medical personnel. However, relying solely on the function of an external force centrifuge is not enough. It also depends on its own performance. Its specific gravity should be maintained between 1.045-1.065g/cm3, exhibiting physiological inertia, and having good thixotropy can effectively ensure the smooth testing process and unaffected testing results.
(EDTA dipotassium anticoagulant)
2、 Anticoagulant
As a frequently used reagent in clinical testing, anticoagulants include various types, such as heparin sodium, heparin lithium, EDTA potassium salt, and disodium salt. When they come into contact with blood in a test tube, they can prevent blood coagulation without destroying the components of the blood sample. If you want to ensure that test results are not affected, you need to pay special attention to their performance indicators:
1. Heparin salt: The main performance indicators for measuring heparin salt are its average molecular weight and potency. When added to a test tube, it must reach a molecular weight of 15000 and a potency of 150-180 IU. When using, pay attention to the dosage added, which will have no impact on the test results.
2. EDTA potassium salt: This is an internationally recognized ideal anticoagulant reagent, but its effectiveness depends on its purity and stability. Reagent raw materials should be of analytical purity, maintained above 99%, and have strong stability when in contact with other reagents or blood, which can also ensure the accuracy of the test results.
3、 Coagulant accelerator, silicifying agent
Coagulant promoters and silicifying agents are also commonly used in test tubes. One is to promote rapid blood coagulation, and the other is to treat the tube wall to ensure no wall sticking. The direct factor that can affect the test results is poor quality. If the coagulant does not play a strong role, the blood cannot completely coagulate, and half of the coagulation generally does not coagulate during the final test, so the results are undoubtedly inaccurate. The same is true for silicified agents. When blood remains on the wall of the tube, causing damage to blood cells, the overall result will be biased.
Therefore, from the above introduction, the performance of blood sampling additives is a key factor affecting the results. If you want to use high-quality additive products, you can choose Desheng. It has a professional research and development team and a quality inspection department, which will continuously track foreign export products to ensure customer satisfaction. Interested parties are welcome to click on the website for consultation!
