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Wuhan Desheng Biochemical Technology Co., Ltd
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Latest company new about Characteristics of chemiluminescence immunoassay
2020/12/22

Characteristics of chemiluminescence immunoassay

Luminol reagent and acridine ester reagent are commonly used in chemiluminescence immunoassay. Chemiluminescence immunoassay has replaced enzyme-linked immunosorbent (ELISA) as a more mainstream in vitro diagnostic method, accounting for more than 50% of biochemical detection methods.   The attraction of chemiluminescence immunoassay as an in vitro diagnostic technique lies in its simplicity. The essence of chemiluminescence is self luminescence, which means that the analytical instrument of chemiluminescence only needs to provide a method to detect the light signal and record the results. The autoluminescence detector needs a closed light sample chamber and a photo detector. The simplest is photo paper or X-ray, or even a visual detector.     The convenience of chemiluminescence detection method makes its application simple and completely automatic, but what is its sensitivity? Chemiluminescence has two inherent advantages.   1. Most of the samples have no background signal, such as they do not emit light.   2. Chemiluminescence detection is not a proportional test, which is different from fluorescence and absorption or colorimetric test. In the fluorescence test, it is very difficult to detect the fluorescent group with small Stokes shift, and the fluorescence is difficult to distinguish from the excitation wavelength.   Another problem is that some stray light will enter the detector, especially when the sample is turbid. In the absorbance test, the fundamental factor limiting the absorbance is to distinguish a small difference between two relatively strong signals.   It should be noted that the sensitivity of the detector to the spectrum of chemiluminescence is as close as possible, and the maximum sensitivity has been obtained. In general, the photomultiplier tube in autoluminescence instrument has the best response to blue light, and is not sensitive to the end spectrum of red light. The solid state detector has a good response to red light.   X-ray films are widely used for chemiluminescence imprinting analysis on nylon, cellulose or PVDF membranes. But we need to keep in mind that X-ray films are only used to detect light signals in the spectrum from ultraviolet to blue, although there are some special films that are sensitive to enhanced green light.   Chemiluminescence detection includes liquid samples and solid samples. The indicators of chemiluminescence detection are usually sensitivity, linearity and dynamic range. Desheng's chemiluminescence reagents include luminol, isoluminol and six acridine ester substrates.
Latest company new about Good news! Hubei new desheng successfully passed the first batch of high-tech enterprises in 2020
2020/12/22

Good news! Hubei new desheng successfully passed the first batch of high-tech enterprises in 2020

Recently, the Office of the National High-tech Enterprise Recognition Management Work Leading Group Office of the Torch High-tech Industry Development Center of the Ministry of Science and Technology released the "List of the First Batch of High-tech Enterprises to be Recognized in Hubei Province in 2020". After a 10-working day public announcement, Hubei Xinde Sheng Material Technology Co., Ltd. successfully passed the certification with its excellent R&D and production technology.   The list of the first batch of high-tech enterprises in Hubei is combined in accordance with the "Administrative Measures for the Accreditation of High-tech Enterprises" (Guoke Fahuo (2016) No. 32), the "Guidelines for the Administration of High-tech Enterprise Accreditation" (Guoke Fahuo (2016) No. 195) and other relevant regulations The evaluation, high standards and strict requirements are effective proof of the company's scientific and technological strength and service capabilities, confirming that 71 high-tech enterprises including Hubei new desheng have passed the high-tech enterprise certification. https://www.vacutaineradditives.com/supplier-278018-blood-collection-tube-additives Hubei new desheng was established in 2017. It is a new technology-based enterprise established on the basis of Wuhan Desheng Biochemical Technology Co., Ltd. (2005). It specializes in the research and development, production and sales of diagnostic reagents. The main products are Vascular additives, chemical light reagents, biological buffers, enzyme preparations, new Trinder's reagents, antigen antibodies and other products. All products and services of the company are subject to targeted research, design and production according to customer requirements, and in terms of blood collection tube additives Formed with independent intellectual property rights and professional production research and development capabilities, has accumulated a wealth of knowledge and experience in the pretreatment of blood samples and has the advantages of professional technical services.   After 3 years of intensive cultivation, Hubei new desheng Material Technology Co., Ltd. has invested a lot of money and energy in product development, customer service and other fields. It has accumulated a lot of accumulation and successfully entered the list of high-tech enterprises to be recognized, marking that Desheng in vitro diagnostic reagents have entered the market. New step. Independent innovation is the life of an enterprise, and it is the foundation for the enterprise to climb the hurdles and grow stronger. As one of the few enterprises in the industry with independent factories, Desheng has a supporting independent research and development base and a high-quality, high-efficiency, high-yield Out of the R&D team.   The general manager of Hubei new desheng said that the approval of the first batch of high-tech enterprises to be recognized is the result of the unity and unremitting efforts of all employees. This is the country’s recognition of Desheng’s advanced technology, and Desheng’s commitment to customers A satisfactory answer sheet. In the next step, the company will increase investment in research and development, and continue to transform research and development results into goals, continue to cooperate with universities to establish its own technology research and development center, comprehensively expand at home and abroad, and use superb technology to give back to the market. The company will not forget the original intention, will continue to upgrade the technology, and continue to improve the quality of service!
Latest company new about Why does tris(hydroxymethyl)aminomethane turn yellow
2020/12/21

Why does tris(hydroxymethyl)aminomethane turn yellow

Tris (hydroxymethyl) aminomethane, commonly referred to as Tris base, is an extremely important raw material and reagent in both chemical and biochemical fields. Its pure form is often presented in the form of pure white powder, however, sometimes we may encounter some customer feedback that Tris in their warehouse has turned yellow. So, why did this happen? Firstly, we need to clarify that Tris is quite stable under dry and sealed conditions. This means that as long as the storage conditions are appropriate, it usually does not decompose and is not easily spoiled. However, once we discover that Tris turns yellow, we need to consider and analyze the possible reasons from multiple perspectives.   The first point we need to consider is the quality issue of Tris products. What we need to confirm is whether the yellowing of Tris was caused by quality issues with the original product or during storage. There are two main methods for synthesizing Tris, each of which requires the use of some raw materials and solvents. It is worth noting that these raw materials and solvents are colorless in their pure state. Therefore, in the normal synthesis process, as long as the equipment is clean, Tris products themselves will not appear colored.   Based on this, we can infer that the possibility of Tris turning yellow due to product quality issues is not very high. Unless poor quality raw materials are used during the synthesis process, or if the raw materials contain some colored impurities, it is possible for Tris products to appear colored. In addition, if the synthesis equipment is not cleaned thoroughly, it may also cause the product to be contaminated, resulting in color. However, this situation can generally be resolved through simple dissolution and filtration steps.   Next, we need to consider the potential issues that Tris may encounter during storage. Although Tris dry powder is not easily decomposed and is not used as a nutrient by microorganisms, it is not easy to breed bacteria. However, Tris has a characteristic that it easily absorbs moisture. When the sealing of Tris is poor or the humidity in the storage environment is high, it will absorb moisture from the air more quickly. Once moisture is absorbed, Tris becomes alkaline, and this alkaline environment easily attracts carbon dioxide from the air. After the reaction between carbon dioxide and Tris, it will cause Tris to deteriorate, resulting in yellowing.   In addition, if there are microorganisms present in the storage environment, these microorganisms may also grow and reproduce on Tris, further accelerating its spoilage process. Therefore, in order to prevent Tris from turning yellow, we need to ensure that its storage environment is dry and clean, and to do a good job of sealing.   Here, I would like to specifically mention Desheng Company. As far as I know, Tris produced by Desheng Company has very guaranteed quality. Whether packed in a bucket or a bottle, its sealing is relatively good and it is not prone to moisture absorption and spoilage. Therefore, if customers experience yellowing when using Tris from Desheng Company, it is likely due to storage environment issues.  
Latest company new about Brief introduction and preparation method of biological buffer bicine
2020/12/21

Brief introduction and preparation method of biological buffer bicine

Bicine is an amphoteric amino acid buffer. It is active in the range of pH 7.6-9.0 (PKA = 8.3 at 25 ° C). Recommended buffer for low temperature biochemical work. Bicaine was used to prepare stable serum guanosine substrate solution. A method of protein separation using dihydropyridine in thin layer ion exchange chromatography has been reported. Dihydropyridine has been used for peptide and protein crystallization.   In biochemical research, buffer solution is often used to maintain the pH value of experimental system. The change of pH value of solution system in research work often directly affects the effect of our work. If the pH value of extraction enzyme experimental system changes or changes too much, the enzyme activity will decrease or even completely inactivate. Therefore, we should learn to prepare buffer solution     Standard for finished buffer   Preparation method of bicine solution (about 1-2l) (1) 0.1M solution (a): bicine 16.317g/deionized water 1000ml (2) 0.1M NaOH solution (b): 4G NaOH / 1000ml deionized water (3)pH 5.1 1,000ml(A)+0ml(B) (A):(B)=5:0 pH 7.8 1,000ml(A)+200ml(B) (A):(B)=5:1 pH 8.2 1,000ml(A)+400ml(B) (A):(B)=5:2 pH 8.6 1,000ml(A)+600ml(B) (A):(B)=5:3 pH 10.4 1,000ml(A)+800ml(B) (A):(B)=5:4   * temperature 20 degrees. * if you need to adjust to a specific pH, use a pH meter. * if you don't want to join Na, please use KOH.   Hubei xindesheng Material Technology Co., Ltd. specializes in the production of various biological buffers, including Tris, Tris HCl, bicine, caps, mops, taps, EPPs, MOPSO, HEPES, pops, if necessary, please contact us for details.
Latest company new about Method for regulating the performance and stability of carbomer gel
2020/12/20

Method for regulating the performance and stability of carbomer gel

Carbomer is a popular raw material in the chemical industry. It is a high-molecular polymer material. It is usually used as a thickener, gel, and suspending agent in creams and emulsions for daily chemical products. It is also listed in the Pharmacopoeia. Pharmaceutical auxiliary materials are used as dispersants, diluents or carriers for medicinal ingredients, as well as additives for animal feed in food.   The reason why carbomer has a good gel and thickening effect is because of its special molecular structure. Carbomer is a kind of polyacrylic acid material, which can also be regarded as carboxyvinyl. The bond position for polymerization is the carbon-carbon double bond of olefin, and the carboxyl group remains.                                                                     Carbomer gel performance and stability judgment   When the carbomer dissolves in water, the carboxyl group ionizes the hydrogen ion and shows a negative charge. The carboxyl group and the carboxyl group in the molecule repel each other with the same charge, so that the molecule slowly expands, which makes the carbomer have good swelling properties in water . It takes a long time for water molecules to diffuse into the carbomer molecules, and after swelling, a gel with a higher viscosity will be formed. When the pH is 6-11, the viscosity of the gel is relatively high. When the pH is 8, the carboxyl groups in the molecule are basically completely dissociated, the repulsive force in the molecule increases to the maximum, and the viscosity reaches the maximum.   When carbomer is dissolved in water to prepare a gel, it is best to soak it in deionized water for 24 hours, and then mechanically stir it for half an hour. Neutralizing carbomer usually uses triethanolamine and EDTA-2Na as gel stabilizers. The presence of the hydration film on the surface of the carbomer gel makes the gel relatively stable. The greater the degree of dissociation of the carboxyl group, the less free water content in the gel and the less likely to grow bacteria. The degree of hydration of the gel can be judged by the sliding time of the gel on the wall of the beaker. Products with the same viscosity but different hydration speeds indicate different gel stability.   From the above content, it can be concluded that the gel performance or viscosity of carbomer is adjusted by the pH value of the gel, and the viscosity is maximum when the optimal pH value is reached; the stability of the gel can be determined by the degree of hydration. Judge, and adjust and control. The carbomers produced by Desheng are divided into 940 and 980 types, which can be selected according to their own needs and sample test conditions.
Latest company new about How to determine if the biological buffer raw material has expired
2020/12/20

How to determine if the biological buffer raw material has expired

Biological buffer raw materials play an important role in numerous biochemical and bioengineering applications. To determine whether a biological buffer raw material has expired, multiple factors such as appearance, chemical properties, performance, storage conditions, and supplier information need to be considered comprehensively. In practical applications, any buffer raw materials suspected to be expired or have quality issues should be tested and evaluated from multiple perspectives to ensure smooth experimentation or production, and to avoid experimental failure or product quality problems caused by the use of expired buffers. Appearance inspection 1. Color change: Many biological buffering agents have specific colors under normal conditions. For example, various buffer materials such as Tris, HEPS, CAPS, etc. appear white. If there is a significant change in the color of the buffer raw material, such as yellowing, browning, or turbidity or precipitation of the prepared solution, it is likely that it has undergone chemical changes or been contaminated, which is an important sign of expiration or deterioration. 2. Physical form change: Normal biological buffering agent raw materials may be in powder form. If the powder form raw materials have clumping, and the crystalline form raw materials have obvious deliquescence or deformation, it may indicate that their quality has changed. For example, the clumping of powdered buffering agents may be due to the absorption of moisture from the air, which can alter their solubility and buffering capacity in solution, thereby affecting their application effectiveness in experiments or production. Chemical property testing 1 PH measurement: The core function of biological buffering agents is to maintain the stability of the pH value of the solution, so measuring their pH value is a key step in determining whether they have expired. Use an accurate pH meter to measure the pH value of the prepared buffer solution according to standard operating procedures. If the measurement result deviates significantly from the standard pH range of the buffer under normal conditions, it may indicate that the buffer has deteriorated. Perhaps due to the reaction between buffer molecules and substances in the environment, their acid-base balance changes, resulting in the loss of their original buffering capacity. 2. Purity analysis: Using appropriate analytical methods to detect the purity of buffer raw materials is also an important means of determining whether they have expired. Common methods include liquid chromatography (HPLC), gas chromatography (GC), mass spectrometry (MS), etc., which can accurately detect the content of the main components in the buffer and the presence of impurities. Performance testing 1. Buffer capacity measurement: Buffer capacity is an important indicator for measuring the performance of biological buffering agents. The buffering capacity can be determined by gradually adding a small amount of strong acid or strong base to the buffer solution, and then measuring the change in pH value of the solution. If the buffering capacity of the buffer is found to be significantly lower than its standard value, it indicates a decrease in its buffering capacity, which may be due to molecular structure changes caused by expiration or the influence of impurities. 2. The impact on biological systems: For some buffering agents used in biological experiments or production of biological products, their expiration can also be determined by observing their impact on the biological system. For example, in cell culture experiments, cells are placed in a medium containing a suspected expired buffer to observe their growth status, morphological changes, and other indicators. If cells experience slow growth, abnormal morphology, or massive cell death, it is likely that the buffer has expired and its quality changes have had adverse effects on the cells.   Supplier information and batch records 1. Production date and shelf life labeling: First, check the production date and shelf life information labeled on the packaging of the buffer raw material. This is the basic criterion for judgment, but it should be noted that the shelf life is an estimated value under specific storage conditions. If the actual storage conditions do not match the recommended conditions, even within the shelf life, it may have deteriorated. 2. Supplier Quality Control Record: Contact the supplier to obtain the quality control record for this batch of buffer. Some legitimate suppliers will conduct strict quality inspections on each batch of products, including the determination of purity, pH value, buffer capacity, and other indicators. By reviewing these records, we can understand the quality status of this batch of buffer at the time of leaving the factory, as well as whether there are any differences compared to previous normal batches. If the quality control records of the supplier show that some indicators of the batch are close to the critical value or have significant differences from the standard batch at the time of leaving the factory, then more caution should be taken when using it, and other testing methods should be combined to determine whether it has expired. As a manufacturer of biological buffer raw materials, Hubei Xindesheng always adheres to the concept of quality first. With advanced production technology and strict quality control system, we carefully screen raw materials and accurately control every aspect of production. Its products cover multiple types and can meet the needs of different biological experiments and industrial production. If you have any relevant intentions, please feel free to click on the website for consultation at any time!  
Latest company new about What should be paid attention to when using enzyme products?
2020/12/19

What should be paid attention to when using enzyme products?

  Because enzymes have a good catalytic effect, professional enzyme preparation manufacturers will use scientific methods to extract enzymes and make them into enzyme preparations that can be used in a variety of industries. Although enzyme preparations have high safety in use, However, you should still pay attention to related matters when using it. Next, Desheng will give us a detailed introduction.     1. Pay attention to the type and dosage of use   There are many types of enzyme preparations, and the types of enzyme preparations used in the production of each industry are not exactly the same, mainly because different types of enzymes have different functions. For this reason, when companies use enzyme preparations, they must select the appropriate type of enzyme preparation according to the actual use and purpose of use and add it as appropriate, so as to avoid adding too much or too little to achieve the desired effect.   2. Pay attention to control temperature and pH   Since the essence of enzyme preparations is protein, it is said that as long as it is a factor that affects the protein, it will usually affect the activity of enzyme preparations. Therefore, when using the enzyme preparation produced by the enzyme preparation manufacturer, we must pay attention to the preservation and use of the temperature to avoid too much temperature and the loss of the activity of the enzyme preparation.   3. Keep away from heavy metal ions   In addition to improper temperature environment and pH value that will cause the activity of enzyme preparations to be lost, there are also heavy metal ions in some articles that react with enzyme preparations or combine with essential groups in them to cause enzyme preparations Lose its due activity. Therefore, the use of enzyme preparations must be careful to keep it away from heavy metal ions.   The purpose of using enzyme preparations in any industry is to improve the production quality and efficiency of products. Therefore, in addition to choosing trusted enzyme preparation manufacturers to purchase suitable products, companies must also add appropriate dosages according to the actual situation. In addition, it is necessary to create a good temperature and acid-base environment for the use of enzyme preparations to prevent enzyme preparations from losing activity. Desheng has dozens of enzyme preparation products, which are mainly used in biochemical testing and biochemical experiments. Compared with industrial Enzyme preparations have better purity and activity.
Latest company new about Storage and transportation temperature of Trinder's reagent Daos
2020/12/19

Storage and transportation temperature of Trinder's reagent Daos

Name: n-ethyl-n - (2-hydroxy-3-sulfopropyl) - 3,5-dimethoxyaniline sodium salt,DAOS reagent CAS No.: 83777-30-4 Molecular formula: c13h20nnao6s Molecular weight: 341.36 Purity: 99% Moisture: ≤ 0.5% Less than 15 ppm Ignition residue: ≤ 0.1 Description white or light blue powder. Oxidizing chromogen reagent Store and transport at 2-8 ° C, sealed and protected from light   Daos white crystal powder   We usually keep the temperature of Daos at 0-5 ℃. However, in the process of use, we usually re seal the Daos which has not been used up, or replace the packaging bottle with a new one for sealing treatment. Otherwise, once the product absorbs moisture, it will lead to caking or beige color.   Our company packaged and wrapped DAOS in transportation process, wrapped it with pearl foam mattress, and then added 2-3 packages of ice to avoid high temperature during transportation and affect the characteristics of the product.   Daos is one of  the new Trinder's reagents. It is a highly water-soluble aniline derivative, which is widely used in diagnosis and biochemical tests. In the colorimetric determination of hydrogen peroxide activity, it has some advantages over the conventional chromogenic reagent   Our company strives to do a good job in the process of R & D, production, sales and transportation, and also in order to let customers feel at ease about our products, we Desheng technology to achieve: Based on sincerity, taking morality as the first, quality first, leading technology to serve the majority of consumers.
Latest company new about Covid-19 nucleic acid detection, do you choose the right virus preservation solution?
2020/12/18

Covid-19 nucleic acid detection, do you choose the right virus preservation solution?

At present, the novel coronavirus control and prevention form is still very severe. As the first step in nucleic acid detection, the importance of sample collection and preservation is beyond doubt. The inspection industry often says "garbage in, garbage out (garbage specimen results)", the most important factor is sampling. If there is a problem with the sample collection, then the following work is done well, and the results are invalid. Choosing the right virus preservation solution and collection tube can make the new crown detection get twice the result with half the effort! At present, almost all virus preservation solutions on the market directly preserve live viruses, leading to a high risk of infection for medical staff in sampling, transportation and testing. In view of this situation, the first line of anti epidemic disease needs the sample preservation solution which can directly inactivate the virus. However, it should be noted that when inactivating the virus, we should also consider whether the preservation solution can stably preserve the integrity of virus nucleic acid To avoid the degradation of nucleic acid in the sample before detection, resulting in "false negative" of nucleic acid detection. Desheng contains no guanidine salt virus preservation solution to minimize the risk of "false negative".   We compared the effects of preservation solution containing guanidine hydrochloride, guanidine isothiocyanate and guanidine salt free preservatives at 37 ℃. The results showed that the main component was guanidine salt, the preservation effect was not ideal!   Under the same conditions of 37 ℃, the preservation efficiency of viral nucleic acid is basically 100% after 1-7 days of storage; however, the preservation efficiency of viral nucleic acid gradually decreases with the use of other two guanidine salt preservation solutions, and it is lower than 20% by the seventh day, indicating that RNA is undergoing severe degradation over time! Guanidine salt (guanidine isothiocyanate or guanidine hydrochloride, etc.) is a classical protein denaturant, which is often used for cell lysis in nucleic acid extraction, and can also achieve the effect of virus inactivation. However, guanidine salt does not have the ability to preserve viral nucleic acid at room temperature, which is easy to cause sample degradation. Therefore, it is not suitable for the preservation of new coronavirus samples. Therefore, it is strongly recommended that you choose non guanidine salt Components of the virus preservation solution.   Here, we appeal to the majority of medical workers to pay attention to the following aspects when selecting virus preservation solution if your sampling purpose is nucleic acid detection and you do not need to cultivate live virus:   1. The virus preservation solution can be used to inactivate the virus At present, nucleic acid detection is to detect the viral RNA in the sample, which needs to split the virus. Therefore, as long as the integrity and stability of the viral nucleic acid can be ensured, there is no need to preserve the live virus. Therefore, in the current situation of fighting against the new coronavirus epidemic situation, it is more ideal to inactivate the virus while collecting samples.   Some manufacturers have introduced inactivated preservation solution on the market, but the inactivated component is guanidine salt. The results of comparative experiments show that guanidine salt preservation solution does not have the ability to preserve virus nucleic acid at room temperature, which is easy to cause sample degradation and is not suitable for the preservation of new coronavirus samples. Therefore, we recommend virus preservation solution containing non guanidine salt protein denaturant It can inactivate the virus and ensure that the virus nucleic acid does not degrade at room temperature.   2. The volume of preservation solution in the sampling tube should be appropriate It is very important to select the appropriate volume of preservation solution: ① if each sample is sampled separately, it is recommended that you select a virus sampling tube with 1ml preservation solution. The sampling volume can not only meet the requirements of nucleic acid extraction and detection in the downstream, but also the virus concentration is three times higher than that of 3ml preservation solution! ② In case of large-scale preliminary screening and mixed detection, the swab samples of 3-5 people are placed in the same sampling tube. It is recommended that you select a virus sampling tube with 3ml preservation solution, so that the sample size can meet the demand of downstream nucleic acid extraction, improve the detection efficiency and reduce the detection cost.   3. Virus preservation solution that can be used to transport and store samples at room temperature Because of the instability of RNA, the traditional virus sampling tube needs to be transported to the laboratory within 48 hours under the condition of 4 ℃. If the transportation temperature is not up to the standard, it may cause the degradation of virus nucleic acid and lead to the "false negative" test result! In contrast, if kangweishiji can transport and keep the virus nucleic acid stably at room temperature, the problem of sample transportation can be solved, and the accuracy of detection results can be improved.   4. The virus preservation solution that can protect the sample from high temperature inactivation is used According to the relevant guidelines of the National Health Commission, the samples should be inactivated at high temperature (above 56 ℃ for 30min) before extracting viral nucleic acid. However, Beijing Center for Disease Control and prevention, Beijing Research Center for preventive medicine and other institutions are in clinical The paper published by chemistry showed that high temperature inactivation could lead to the degradation of viral nucleic acid, thus reducing the detection rate of viral nucleic acid, which was one of the reasons for the high false negative rate of nucleic acid detection of new coronavirus.   The results showed that high temperature inactivation had no significant effect on the integrity of coronavirus nucleic acid.   The virus preservation solution developed and produced by Desheng can be divided into inactivated and non inactivated types. Different preservation solutions are selected according to different experimental requirements and detection conditions. If you have any questions or needs, please call us for details. Choosing Desheng virus preservation solution is your right choice.
Latest company new about Desheng is the first choice for high quality blood anticoagulant heparin lithium
2020/12/17

Desheng is the first choice for high quality blood anticoagulant heparin lithium

Heparin lithium is a chemical with a white to nearly white appearance. There was no significant difference in TP, Aso, UA, alt, Mg, Cl, TC and CRP between heparin lithium anticoagulant plasma and serum (P > 0.05). There were significant differences in HBD, LDH and TBA between heparin lithium anticoagulant plasma and serum (P < 0.05). Therefore, except for HBD, LDH and TBA, the correlation between heparin lithium anticoagulant plasma and serum is good. Therefore, it is feasible to use heparin lithium anticoagulant plasma instead of serum in life detection, which can be used as an important detection method.   Basic information of Desheng product heparin lithium Name: heparin lithium CAS No.: 9045-22-1 Purity: ≥ 150 USP units / mg Specification: 10g / bottle, 50g / bottle Storage and transportation: 2-8 ° C   [scope of application]   1. This product is suitable for the collection and anticoagulation of blood samples for clinical biochemical examination and emergency biochemical examination, as well as for blood sample collection and anticoagulation of some Hemorheology items. 2. It is recommended to use heparin lithium as anticoagulant when determining the ion content in blood, because it is the least likely to interfere with the determination of other ions. 3. This product is not a drug and cannot be used as an injection. It is forbidden to inject directly into human body and animal body.   [precautions]   In order to ensure sufficient blood anticoagulation, heparin salt test tube blood collection must be reversed and mixed 5-8 times as soon as possible. Especially when the ambient temperature of blood sampling is higher than 25 ℃, the mixing of blood and heparin lithium must be timely and sufficient, otherwise it is easy to cause blood coagulation or local coagulation.   Heparin anticoagulation is not irreversible anticoagulant, so the test should be completed within 6 hours after blood collection of heparin lithium anticoagulant test tube, otherwise, the test results may have errors.   Heparin may be involved in the metabolism of cell enzymes and ions, so the amount of heparin used may affect the detection results. The dosage of heparin should ensure full and local anticoagulation, so as to ensure that most of the plasma indexes can be repeated within 6 hours, especially ast, alt, TBIL, DBIL, GGT and other sensitive indicators.   Heparin lithium can be used with separation gel at the same time, anticoagulant effect, tube wall silicification, centrifugal conditions, separation gel quality and so on will affect the blood separation effect. It is suggested that high quality plasma samples can be obtained by using the blood separation gel produced by our company. It is suggested to use gamma ray irradiation with a dose of 8-25kgy. The irradiation dose can be determined by the initial colony number.   [warning and prevention]   It is forbidden to use heparin lithium in case of impurities, abnormal smell, color and expiration date. Do not use the heparin solution when it is contaminated with lithium bacteria. This product is a biological preparation, safe, non-toxic and harmless.   Desheng is an old brand blood testing reagent company with 14 years of R & D and production experience, and has a deep research on blood collection additives. If you need heparin lithium enterprise friends can contact directly, looking forward to your consultation!
Latest company new about What kind of carbomer manufacturer is more worthy of cooperation
2020/12/16

What kind of carbomer manufacturer is more worthy of cooperation

Affected by this year's epidemic, Carbomer has become a popular raw material for daily chemical products. Now there are countless manufacturers that provide Carbomer. It can be said that buyers are confused. What kind of Carbomer raw material company is more worthy of choice. Desun’s decades of professional R&D and production experience have accumulated a lot of experience for the company. Its advantages and marketing strategies have laid a solid foundation for itself in the industry. This type of company is worthy of long-term cooperation. In addition, it also needs to have The following three characteristics.     1. Have an exclusive R&D department to master advanced technology   By investigating related companies, we can find that high-quality carbomer manufacturers can master more advanced technologies, conduct in-depth explorations with customers, and negotiate cooperation-related matters. In early 2020, the company invested a lot of capital, manpower and material resources, and now has A group of professional technical backbone personnel, through their R&D personnel working overtime and testing and testing, finally completed the final product of Carbomer. The carbomer raw materials produced are up to standard in all indexes, comparable to international brands, and its transparency is better than that of well-known brands.   2. Short delivery cycle, saving purchase time   With the increasing demand for carbomer, carbomer was in short supply for a while. Fortunately, after the increase in manufacturers, this phenomenon gradually improved. However, there are still many customers who fail to supply ton goods in time. Sheng currently has a professional production base and adopts imported production equipment. The daily output of Carbomer can reach 3-5 tons, which can meet the needs of customers in large quantities. Customers do not have to worry about the delivery cycle.     3. Ability to uphold the principle of seeking truth from facts to solve customers' doubts   Good carbomer manufacturers can usually implement the principle of seeking truth from facts. Whether it is introducing customers to other products of the company or answering questions raised by customers, they will not divorce from reality. Because the company knows that products and rhetoric that are inconsistent with the facts will cause wrong guidance to customers. "Morality-oriented, honesty first" is the foundation for the company to stand firm for more than ten years. Similarly, when encountering quality When there is a problem, Desheng never shirks, but promptly returns and exchanges to ensure that the interests of customers are not harmed to the greatest extent.   Carbomer manufacturers that are worthy of cooperation generally have the three characteristics mentioned above. This part of the content can be used as a summary of the advantages of Desheng, and it can also be a reference for customers to consider during the purchase period. There are a large number of manufacturers of the same type on the market. We hope that customers in need can calmly complete the screening without missing any details. Desun now produces Carbomer 940 and Carbomer 980. Welcome to buy!
Latest company new about Desheng, a high quality manufacturer of Ethylenediaminetetraacetic Acid Tripotassium Salt Dihydrate
2020/12/16

Desheng, a high quality manufacturer of Ethylenediaminetetraacetic Acid Tripotassium Salt Dihydrate

The English name of edta-3k is Tripotassium hydrogen ethylenediamineetraacetate. Its CAS number is 17572-97-3. Its molecular formula is c10h13k3n2o8, and its molecular weight is 406.51372. Its appearance is white crystalline powder. Structure of Tripotassium EDTA   Application of tri potassium ethylenediamine tetraacetic acid 1. As an anticoagulant for blood cell analysis. Ethylenediamine tetraacetic acid (EDTA) as an anticoagulant for blood cell analysis was determined by the International Committee on blood standards (ICSH) in 1993 and has been widely used. In China, the use of edta-k3 anticoagulant for blood analysis is not long, and there are few reports on EDTA dependent thrombocytopenia. Some people think that this phenomenon is an autoimmune disease, because a large proportion of such people have elevated serum immunoglobulin, and have positive anti platelet autoantibodies and anticardiolipin antibodies.   The plasma of such patients can cause platelet aggregation of healthy people when they are incubated with platelets of healthy people, but the plasma of healthy people can not cause platelet aggregation of such patients. When edta-k3 anticoagulant is used in patients with edta-k3 anticoagulant, a large number of PLT gather together, leading to false reduction of PLT count. At the same time, the volume of some PLT aggregates is equivalent to the volume of WBC, and can not be destroyed by hemolysin, which also makes the false increase of WBC count, which will make the classification of WBC appear various inaccurate prompts There must be platelet aggregation or platelet aggregation in the histogram.   Some studies have shown that when edta-k3 anticoagulant is used for blood analysis, it is found that the platelet count is too low for unknown reasons. Therefore, the patient should be manually checked for blood smear and PLT manual counting, or the PLT count should be rechecked by instrument after dilution with non anticoagulant peripheral blood, so as to correctly understand the real level of PLT in patients. In particular, tumor patients, autoimmune diseases, pulmonary heart disease, pregnant women, advanced liver disease and other patients.   2. Preparation of a self-cleaning high borosilicate glass rod. The preparation method comprises the following steps: 1) according to the weight parts, 34-44 parts of aluminum isopropoxide, 1-2 parts of ethylene diamine tetraacetic acid Tripotassium salt and 250-300 parts of deionized water are evenly mixed, the mixture is heated to 40-45 ℃, and the heat preservation treatment is conducted for 2-3 hours to prepare colloidal solution a;   2) According to the weight part, 29-33 parts of tetrabutyl titanate is dissolved in 150-170 parts of ethanol, and then 60-70 parts of ammonia water with mass fraction of 11-15% are slowly dropped into it. After standing for 2-3 hours, 5-9 parts of potassium titanium oxyphosphate are added into the mixture, and after mixing and stirring evenly, colloidal solution B is prepared;   3) Colloidal solution a and colloidal solution B are mixed according to the mass ratio of 3-6:1, and then colloidal solution B is added into the mixture The self-cleaning coating is prepared by mixing and stirring the polyethanolamine with the amount of 1-3%. After cleaning the surface of the high borosilicate glass rod, it is placed in the self-cleaning coating for 10-14 min. after that, it is taken out and put into the high-temperature furnace for sintering treatment to prepare the finished product. In step 1), the addition of potassium EDTA can effectively improve the adhesion performance of the prepared colloidal solution a, improve the dispersion uniformity of AlOOH colloid, and prevent the phenomenon of precipitation;   3. Prepare a kind of thermal insulation coating for building exterior wall. In terms of weight, it contains 80~120 pieces of pure acrylic emulsion, 20~30 parts of Ta2O5-ZnO-SnO2 composite oxide powder, 5~10 parts of three potassium of ethylenediamine acetic acid, 2~5 parts of kaolin, 1~5 parts of borax, 2~5 parts of antifreeze, 5~10 parts of film forming aid, 1.5 1.5 2.3 parts of pyrophosphate, 1~2 1~2 of thickening agent, polyoxyethylene polyoxypropylene pentaerythritol ether and 5~10 nitrobenzene sulfonic acid. To 150.   Through the test, it is found that the introduction of EDTA into the exterior wall coating can significantly improve the acid corrosion resistance of the coating, so that in cities with severe acid rain, the coating can also ensure good service life and is not easy to corrosion and fall off.   Hubei xindesheng material science and Technology Co., Ltd. is specialized in the production and supply of ethylenediamine tetraacetic acid potassium national package, interested parties can contact
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