Home
Products
About Us
Factory Tour
Quality Control
Contact Us
Request A Quote
News
News
Wuhan Desheng Biochemical Technology Co., Ltd
Home ProductsCarbomer

CAS 9003-01-4 Carbomer Gel White Powder Loss On Drying ≤2.0%

China Wuhan Desheng Biochemical Technology Co., Ltd certification
China Wuhan Desheng Biochemical Technology Co., Ltd certification
As a distributor of hospital agent , your Blood Collection Tube Additives is very suit for my needs , i think we have establish a good business with each other , thank you !

—— Tony

I'm Online Chat Now

CAS 9003-01-4 Carbomer Gel White Powder Loss On Drying ≤2.0%

CAS 9003-01-4 Carbomer Gel White Powder Loss On Drying ≤2.0%
CAS 9003-01-4 Carbomer Gel White Powder Loss On Drying ≤2.0% CAS 9003-01-4 Carbomer Gel White Powder Loss On Drying ≤2.0% CAS 9003-01-4 Carbomer Gel White Powder Loss On Drying ≤2.0% CAS 9003-01-4 Carbomer Gel White Powder Loss On Drying ≤2.0% CAS 9003-01-4 Carbomer Gel White Powder Loss On Drying ≤2.0% CAS 9003-01-4 Carbomer Gel White Powder Loss On Drying ≤2.0% CAS 9003-01-4 Carbomer Gel White Powder Loss On Drying ≤2.0% CAS 9003-01-4 Carbomer Gel White Powder Loss On Drying ≤2.0% CAS 9003-01-4 Carbomer Gel White Powder Loss On Drying ≤2.0% CAS 9003-01-4 Carbomer Gel White Powder Loss On Drying ≤2.0%

Large Image :  CAS 9003-01-4 Carbomer Gel White Powder Loss On Drying ≤2.0%

Product Details:
Place of Origin: Ezhou city,Hubei province,china
Brand Name: Desheng
Certification: ISO 9001
Model Number: CAS 9003-01-4,white powder,20kg/paper package
Payment & Shipping Terms:
Minimum Order Quantity: 20kg
Price: Negociated
Packaging Details: 20kg/paper package
Delivery Time: 4-10 days
Payment Terms: L/C, T/T
Supply Ability: 1000kg three days
Detailed Product Description
Color: White Appearance: Powder
CAS: 9003-01-4 Package: 20kg/paper Package
Viscosity 1: 0.2% Aqueous Solution:13000~30000mPa.s Viscosity 2: 0.5% Aqueous Solution:40000~60000mPa.s
Carboxylic Acid Content , %: 56.0~68.0
High Light:

CAS 9003-01-4 Carbomer Gel

,

2.0% Loss Carbomer Gel

,

CAS 9003-01-4 carbomer gel eye

Factors affecting the properties of carbomer gel,CAS 9003-01-4,white powder,Loss On Drying:≤2.0%

 

The carbomer we produce is a white loose powder with strong hygroscopicity. Therefore, it must be placed in a plastic bag in a dry place during storage. When we use carbomer, we usually make a gel and add it to daily chemicals or medical raw materials. What are the factors that affect the properties of carbomer gel? Including the pH value and ionic strength of the medium, the nature of the drug, and the presence of other excipients.

 

Factors affecting the properties of carbomer gel

1. The effect of pH

Since the carbomer polymer has a large number of free carboxyl groups, its pKa value is usually small. When the pH of the medium is less than 4, the carboxyl groups hardly dissociate, and when the pH>4, the carboxyl groups begin to dissociate, the polymer swells, and the viscosity increases. , When the pH value is 8, the dissociation is almost complete and the viscosity is the largest. When carbomer is used as a carrier for basic drugs, after the drug is dissolved, the pH of the medium increases, the degree of carbomer dissociation increases, the gel layer thickens, and the drug release rate decreases, so as to achieve the control of drug release purpose. The pH value of the medium also affects the adhesion of the carbomer gel. When the pH value is lower than its pKa, the gel has a stronger bonding ability and increased adhesion. At the same time, the ionic strength of the medium can change the sensitivity of the carbomer gel to pH. When the ionic strength is high, the carbomer is easier to release protons, and its pKa value decreases, so it can be dissociated and dissolved at a lower pH. rise.

 

2. Influence of ionic strength

In some drug delivery systems, the influence of the drug on the pH and ionic strength of the medium around the gel is not negligible, because the pH of the drug will also affect the properties of the gel, and the effect of acidic drugs is more obvious. The main drug is 2 In the case of 5-dihydroxybenzoic acid, the thickness of the gel layer is about twice the thickness of the gel layer formed by salicylic acid as the main drug, which proves that acid drugs will increase the adhesion of the gel.

 

3. The influence of other excipients

In carbomer gel, if polyvinylpyrrolidone and polyoxyethylene are used as excipients at the same time, it may reduce the mucosal adhesion ability of carbomer gel. This decrease is also related to the concentration and molecular weight of coexisting excipients, and the concentration of excipients is high. (5%), can significantly reduce the adhesion of carbomer gel, when its concentration is reduced to 0.5%, the effect is small. Generally, the pH of the medium cannot change this property of polyvinylpyrrolidone and polyoxyethylene. Magnesium stearate can also reduce the adhesion of carbomer gel because of its hydrophobicity.

Contact Details
Wuhan Desheng Biochemical Technology Co., Ltd

Contact Person: Sales Manager

Tel: +8615071057538

Send your inquiry directly to us (0 / 3000)