Advantages of chemiluminescence reagent acridine ester

In the vast field of modern detection technology, chemiluminescence analysis technology holds a pivotal position due to its significant advantages such as high sensitivity, wide linear range, and easy operation. Among numerous chemiluminescence reagents, acridine ester stands out with its unique properties and has become a powerful tool in many fields such as scientific research and clinical diagnosis.

1, Unique luminescent mechanism, efficient signal generation

The luminescence mechanism of acridine ester is based on its chemical reaction in alkaline hydrogen peroxide solution. When hydrogen peroxide ions attack acridine ester molecules, unstable ethylene oxide intermediates are rapidly generated. The intermediate is extremely unstable and immediately decomposes into carbon dioxide and N-methylacridone in an electronically excited state. When N-methylacridone returns from the excited state to the ground state, it releases photons with a wavelength of approximately 430 nm, producing a strong chemiluminescence signal. This process does not require complex catalysts or additional enhancers, greatly simplifying the reaction system, reducing background luminescence, and improving signal-to-noise ratio. Compared with other chemiluminescence systems, the direct chemiluminescence mechanism of acridine ester enables faster and more concentrated light release, producing high-intensity luminescence signals in a short period of time, providing clearer and more accurate basis for detection.

2, High sensitivity, capturing trace signals

In the field of clinical diagnosis, early diagnosis of many diseases is crucial, and at this time, the levels of biomarkers in the body are often extremely low. Acridine ester, with its high sensitivity, can sensitively detect these trace substances. Acridine ester chemiluminescence technology can accurately identify and measure these extremely trace biomarkers, providing critical diagnostic information for doctors and aiding in early detection and treatment of diseases. In terms of infectious disease pathogen antibody detection, acridine ester can effectively detect hepatitis B surface antibody, hepatitis C antibody, etc., even if the antibody content in the blood is very small, which greatly improves the accuracy and timeliness of infectious disease diagnosis.

3, Quick detection to meet timeliness requirements

In some scenarios where rapid detection results are required, such as clinical emergency testing, detection speed is crucial. The chemiluminescence reaction of acridine ester is extremely fast, and this rapid reaction characteristic enables detection methods based on acridine ester to be completed in a short period of time, greatly improving detection efficiency. In clinical emergency, the use of acridine ester chemiluminescence technology can provide results within minutes for the detection of myocardial infarction markers such as troponin.

4, Good stability ensures reliable results

From a chemical perspective, acridine esters themselves have good chemical stability. Under appropriate storage conditions, acridine esters can maintain their chemical activity for a long time, which makes acridine ester based chemiluminescence reagents have a longer shelf life. In clinical testing, the stability of reagents is crucial to ensure consistency of test results across different time periods and batches. The stability advantage of acridine ester provides a reliable guarantee for clinical diagnosis, avoiding detection errors caused by reagent deterioration.

Acridine ester, as an excellent chemiluminescent reagent, plays an irreplaceable role in modern detection technology due to its unique luminescent mechanism, high sensitivity, rapid detection ability, good stability, and ease of labeling. With the continuous advancement of technology and in-depth research, acridine esters are expected to demonstrate their unique charm in more fields, making greater contributions to human health and social development.

Hubei Xindesheng Materials Co., Ltd. has many years of experience in the production and research and development of acridine esters. A lot of effort has been invested in the research and development of acridine esters. At present, the company's products have been sold to more than 100 countries around the world, and most of them have received positive reviews and repurchases. The product quality is excellent, and prices are discounted. If you are interested in learning more, you can call us for consultation. Desheng welcomes your call.