Heparin, as an important anticoagulant, plays an indispensable role in medical and laboratory applications. Its anticoagulant effect is strong, and heparin sodium and heparin lithium, as common binding forms, have unique advantages, making them one of the highly respected choices in blood collection additives.
1、 Heparin anticoagulant effect
Heparin plays a significant role in anticoagulation, starting from enhancing the affinity between antithrombin 3 and thrombin, accelerating the inactivation of thrombin, and inhibiting platelet adhesion and aggregation. It can enhance the activity of protein C and stimulate the release of anticoagulant and fibrinolytic substances from vascular endothelial cells. Heparin exhibits multiple anticoagulant properties, and both heparin sodium and heparin lithium possess these anticoagulant properties.
2、 Clinical application of heparin sodium and heparin lithium
Heparin sodium and heparin lithium are important substances in anticoagulant blood vessels, and processed blood samples can be used to measure pH and electrolytes. At the same time, due to the addition of heparin, the anticoagulant enzyme in the blood collection vessel prolongs the clotting time of the sample, and is also suitable for projects such as red blood cell fragility test, blood gas analysis, red blood cell compression test, erythrocyte sedimentation rate and universal biochemical determination. However, it should be noted that heparin is not suitable for blood coagulation experiments, as excessive heparin can cause significant changes in white blood cells and interfere with accurate counting.
3、 Selection of heparin sodium and heparin lithium
The two common binding forms of heparin, heparin sodium and heparin lithium, may be confusing in their selection. Although they are all binding forms of heparin, there are significant differences in their effective ion binding, resulting in significant differences in the degree of dissociation. Although experimental comparisons have shown that heparin lithium is slightly better than heparin sodium in terms of efficacy, the dosage used in vacuum blood collection also varies. But in fact, their use is based on experimental requirements, and their anticoagulant effects are consistent, and they can both exert stable performance in clinical practice.
So from the above, it can be seen that the heparin sodium and heparin lithium in the additive for blood collection are both good and play irreplaceable roles in medical diagnosis and laboratory testing. Their advantages make them the preferred choice in many medical and laboratory fields. As an advantageous supplier of heparin sodium and heparin lithium, Desheng can provide raw material powders with low impurities and excellent anticoagulant effects, which are ready to use and convenient for storage and transportation at a competitive price. If you have any interest, please feel free to contact us for purchase!
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