Preparation Of Heparin Sodium Solution

Heparin sodium is an ideal anticoagulant, mainly extracted from pig intestines. It is widely used in cosmetics, blood vessels and antithrombotic drugs. Among these uses, added to the collection vessel as in vitro anticoagulant is used the most, but because the production of heparin sodium is mostly powder, in use to prepare into solution, many people do not know how to prepare, so the next focus for you to introduce.

Bottled heparin sodium

Preparation and addition of heparin sodium

Heparin sodium is usually prepared with normal saline. The regular dosage of 1 ml of blood corresponds to 20IU of heparin sodium, and 5 ml of blood corresponds to 100IU of heparin sodium. The solution sprayed inside the vacuum sampling vessel is between 20 ul-25 UL, which means the concentration of heparin sodium is roughly 100IU/20UL.

Depending on the ratio, it's also easy to figure out how much heparin to add to 1 liter of solution, which is 100*50*1000=5000000IU. If the titer of heparin sodium is 160IU/mg, then 31.25g of heparin sodium needs to be added. After being dissolved in water, it is configured as a solvent and sprayed around the tube wall directly and evenly to achieve anticoagulation effect.

Heparin sodium parameters:

Does heparin sodium solution need to be dried?

Since it is sprayed on the wall of the tube in solution state, it needs to be dried in the oven before use. The purpose of this is mainly to reduce the influence of heparin volume on the concentration of drugs in plasma, but it does not affect the use without drying. And heparin sodium is resistant to high temperature, generally in the temperature of 80 degrees can be dried for a few hours, but it is best to pay attention to the drying of heparin sodium is ready to use.

The prepared heparin sodium solution was stored

After the preparation of heparin sodium solution, its conventional storage method is stored at 0-4 degrees Celsius, can not be shelving for a long time, easy to breed bacteria, and should be guaranteed to be ready to use, the longest storage period is not more than one week, in order to prevent the performance of heparin sodium change, anticoagulant effect is not good.

Desheng Biochemical is a manufacturer specializing in the production of heparin salts. Both heparin sodium and heparin lithium are high-quality heparin with a titer of 150IU/mg, which can effectively meet the requirements of vacuum blood vessel extraction additives. Product quality by professional R & D personnel control, after-sales service personnel to solve, to protect the rights and interests of customers. If you have related needs, welcome to click the website or call for details!