Tris, cas77-86-1, also known as tromethamine, is a common reagent, which is widely used in industrial synthesis, biochemical detection and biopharmaceutical fields. In addition, Tris can also be used to prepare gold nanoparticles.
Tris (hydroxymethyl) aminomethane is widely used in biochemistry and molecular biology experiments as a common raw material for buffer preparation. Tris is also an intermediate for the preparation of surfactants, vulcanization accelerators and some drugs. Because it has three equal hydroxyl groups, it can also be used as a good reducing agent. In the alkaline condition of sodium hydroxide, it can reduce chloroauric acid solution to prepare stable gold nanoparticles. This method is non-toxic and pollution-free, and belongs to green reduction method.
At present, the classical synthesis methods of gold nanoparticles are sodium citrate reduction method, phase transfer method and seed growth method. These methods are the easiest to modify the surface of gold nanoparticles, but the preparation and modification of these methods have certain toxicity. In order to reduce the toxicity of gold nanoparticles to organisms in experiments and make them better used in biomedical field, researchers have been continuously developing new green reduction methods in recent years.
For the first time, Tris was used as a reducing agent to reduce chloroauric acid solution under alkaline condition by ultrasound without adding other stabilizers. The environmentally friendly and biocompatible gold nanoparticles were synthesized. Gold nanoparticles with different sizes can be prepared by adjusting the experimental conditions.
Compared with other green synthesis methods, the experimental conditions are more mild and the operation is simple. This provides a new research idea and theoretical basis for the synthesis of green, pollution-free, low toxicity, low cost and high biocompatibility gold nanoparticles.
Since 2005, Desheng has developed and produced biological buffers, blood collection additives, color reagents and chemiluminescence reagents. The biological buffers include Tris, HEPES, caps, mops, etc. Desheng has always been adhering to the concept of quality first, products from the selection of raw materials to production and packaging layer upon layer, only to provide customers with quality products, do not forget the original intention can Zhiyuan.
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