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What are the advantages of carbomer as a pharmaceutical excipient?

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What are the advantages of carbomer as a pharmaceutical excipient?

Since its first application in the 1950s, Carbomer has been highly respected in pharmaceutical circles. Carbomer has been widely used in the research and production of cosmetics and drugs abroad, and has been included in the Pharmacopoeia of many countries, but it is still a relatively new material in China.

 

Carbomer has many uses in drug punishment. For example, it can be used as a disinfectant gel, Carbomer Eye Drops, Carbomer drug delivery adhesive, Carbomer skin disinfectant gel, and controlled release material. What are the advantages of carbomer as pharmaceutical excipients? Let's give you a solution.

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Carbomer can be used as ophthalmic gel. At present, the common eye drops used in clinic are short of drug retention in the eyes, resulting in poor drug absorption. But carbomer is different, it not only does not have the above shortcomings, but also in clinical practice it can relieve endocrine disorders, dry eye symptoms caused by insufficient tears, can reduce inflammation and treat presbyopia.

 

The new bromide eye drops used in the treatment of dry eye disease in clinic is effective because of its short contact time with cornea. Instead, the gel made with carbomer has a significant effect on promoting weeping, and it will produce the greatest effect after 1 hours.

 

In addition to the ingredients of ophthalmic gel, in the oral protein polypeptides drug delivery system, using carbomer bags around the milk drops can increase the adhesion time between the milk drops and the intestinal wall mucosa. The microemulsion containing carbomer 940 can increase the intestinal absorption of drugs such as desmopressin, while carbomer's protease inhibition and absorption promoting action are also beneficial to increase the drug. Absorptivity.

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Carbomer 940 is not only easy to smear, but also can absorb tissue solution, which is conducive to the discharge of secretions. It has good stability, smooth and comfortable skin feeling, easy to clean, and good air permeability. Some oral drugs are made into gel through skin, and become topical drugs, which reduces the stimulation of internal organs. When used for skin external use, Carbomer also has moisturizing property, can lubricate skin, protect skin from pollution and stimulation, and has anti infection effect.

 

It should be noted that carbomer is used as a pharmaceutical excipient and does not have any other drug effects. It is used as gel, thickener, dispersant or suspending agent as a carrier medium for medicine. Desheng is a professional manufacturer of carbomer. Its products mainly include carbomer 980 and carbomer 940. The customer response is very good. Carbomer is a new type of polymer material. Excellent pharmaceutical excipients will play a certain role in promoting the use of new excipients and the research of new preparations in China.

Pub Time : 2021-02-18 20:05:31 >> News list
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