CAS NO. 9001-42-7 Enzyme Preparation α Glucosidase 99.0~101.0% Assay

Alpha glucosidase, as an important member of the starch hydrolase family, is widely used in the food and fermentation industry, chemical industry, as well as clinical testing and disease treatment. The research on it has always been highly valued by people. The α - glucosidase inhibitor is a relatively mature drug for treating diabetes and has been widely used in clinical practice. Let's take a closer look at its more detailed information.

Basic properties of alpha glucosidase:

Clear amber to dark brown liquid formulations, or white to light brownish yellow powders, odorless and tasteless, soluble in water, insoluble in ethanol, highly sensitive to temperature, pH, and various factors that cause protein denaturation, and easily affected by external conditions to alter their own conformation and properties. It is a protein with biocatalytic function, widely present in animals, plants, and microorganisms.

Alpha glucosidase

How does alpha glucosidase achieve glycemic control

Alpha glucosidase plays an important role in the absorption process of food, and food must bind to this enzyme in order to be absorbed

Digestion and absorption. Alpha glucosidase inhibitors slow down the absorption of glucose in the intestine and reduce postprandial hyperglycemia by inhibiting alpha glucosidase on the intestinal mucosa. Since it does not stimulate insulin levels and does not cause hypoglycemia on its own, it has

Helps reduce blood sugar fluctuations and keeps blood sugar levels stable throughout the day.

Catalytic properties of alpha glucosidase:

Glucosidase is widely present in animals, plants, bacteria, and fungi, as long as it is a carbohydrate powered enzyme

Cellular structures are present in all living organisms. Due to the bonding modes of glucosidic bonds, they are divided into alpha and beta types, and there are also two corresponding hydrolytic enzymesTypes. The hydrolysis of α - glucosidase can cleave from the non reducing ends of α - glucosides, oligosaccharides, and glucans

Opening the α -1,4-glycosidic bond releases glucose; Glycosylation can also convert free glucose residues into α -1,6 glycosidic bonds

Transfer to another glucose or maltose substrate to obtain non fermentable low molecular weight isomaltose IMO.

Source and distribution of alpha glucosidase

Alpha glucosidase is widely distributed in nature, with a wide variety of species and diverse properties, and almost exists in all living organisms. At present, the majority of α - glucosidase enzymes that have been studied come from microorganisms, except for a few from plants and animals

In the middle. Some strains of bacteria, fungi, and yeast can secrete this enzyme, among which Aspergillus niger produces the most enzyme, which is sold in the market

Most alpha glucosidase products are produced through fermentation by Aspergillus niger.

Desheng produces a variety of enzyme preparations and has been continuously developing and researching advanced biochemical reagents to meet the needs of medical laboratory technology development worldwide. The alpha glucosidase produced by Desheng is a white, slightly yellow amorphous powder with a specific activity of ≥ 12U/mg, which is easy to transport and store. Compared with industrial enzyme preparations, it has better purity and activity. We can provide samples for customers who need it.