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EDTA Anticoagulant Blood Collection Tube Additives,
Heparin Anticoagulant Blood Collection Tube Additives,
EDTA Heparin Anticoagulant
Anticoagulant used in blood collection tubes, EDTA anticoagulant, heparin anticoagulant
Anticoagulant is a chemical agent or substance that can prevent blood from clotting. Commonly used anticoagulants include heparin, ethylenediaminetetraacetate (EDTA salt), citrate, and oxalate. Although we have to choose the appropriate anticoagulant according to different needs in practical applications, their basic performance is still the same as blood coagulation, so we need to know a few points in the process of use:
1. After blood collection with anticoagulant blood collection tube, how to place it and how long can it be placed?
In the Department of Hematology and Laboratory Medicine, we often use anticoagulation tubes. As the name suggests, anticoagulation tubes are blood collection tubes with anticoagulant added. They are mainly used to preserve blood and prevent blood clotting. Generally speaking, how long an anticoagulant tube can store blood is mainly determined by the anticoagulant substance in the anticoagulant tube, which mainly includes heparin and liquid. In addition, the storage time is different for different test items. If it is a morphological examination such as blood routine, it can be stored at 2 to 8 degrees for 7 days, if it is a biochemical test, it generally does not exceed 12 hours. If it is a blood glucose test, the result will be inaccurate after 2 hours without refrigerating and adding other reagents.
2. Several factors affecting the anticoagulant effect:
|1||The blood flow is not smooth, causing it to coagulate without mixing with the anticoagulant.|
|2||Insufficient or invalid anticoagulant dose.|
|3||The blood sample and the anticoagulant are not completely mixed (especially the solid anticoagulant, such as the blood routine) or the staff forgot to mix it due to the error of the staff.|
|4||The cuff is used for too long, which accelerates the coagulation reaction. Microagglutination that is not easy to find can lead to abnormal results, such as the influence of microagglutination on blood routine and coagulation series tests.|
|5||Use anticoagulant correctly. Normally, clinical tests usually use serum as specimens and do not require anticoagulation.|
However, when anticoagulants are required for some special test items, attention should be paid to selecting the appropriate anticoagulant and the ratio of anticoagulant to blood. Prevent the specimen from clotting or changing the morphology of red blood cells. Special attention should be paid to the anticoagulant containing K salt and Na salt cannot be used to measure K+ and Na+ specimens, and those containing EDTA and oxalate cannot be used to measure Ca++ specimens, because Ca++ can form insoluble substances with them. Oxalate and fluoride cannot be used for the determination of enzymes and specimens determined by enzymatic methods, because they can activate or inhibit the activity of certain enzymes. For example, oxalate can inhibit the activity of amylase, acid phosphatase, and lactate dehydrogenase. . Fluoride can activate urease and amylase.
Desheng is a long-established manufacturer of blood collection tube additives, and has formed independent intellectual property rights and professional production and R&D capabilities in blood collection tube additives. It has provided products and raw material solutions for more than 100 domestic and foreign manufacturers. Blood specimen anticoagulation products include heparin sodium, heparin lithium, trisodium citrate, dipotassium EDTA, EDTA tripotassium, potassium oxalate, etc.; blood specimen procoagulant products include blood coagulation powder, blood coagulant, etc.; blood specimens The materials used in the pre-treatment include separating glue, siliconizing agent and so on.
Contact Person: Vicky Zhao