As one of the important raw materials in the field of biochemistry, heparin plays its role in many aspects, such as the preparation of medicine, testing, cosmetics, etc. Among them, the most widely used is used as an in vitro blood anticoagulant, whether it is heparin sodium or heparin Lithium is an anticoagulant reagent favored by medical institutions.
Although heparin sodium and heparin lithium are both used as in vitro blood anticoagulants, they are both white powder in appearance, have no peculiar smell, and are soluble in water, but this does not mean that they are exactly the same, and there are still many differences. Let me introduce the difference between heparin sodium and heparin lithium.
1. The difference of binding ions
Even though heparin sodium and heparin lithium exist in another form of heparin, the ionic structure is very different, which makes heparin sodium and heparin lithium look the same in appearance, but they are essentially different , and their degree of dissociation is also different. Generally speaking, lithium heparin is replaced from sodium heparin.
Second, the difference in the amount of additives in blood collection tubes
2. heparin and lithium heparin are widely used in vacuum blood collection tubes, but they are not added blindly. They need to be added according to industry standards. There is a fundamental difference in the amount of heparin added. The standard dosage range of heparin lithium in the industry is 9.41-281U unit/per milliliter, while heparin sodium is 121U~301U per milliliter of blood. Sodium is 151U-201U.
3. Differences in white blood cell count results
In the detection experiment, it can be known that heparin sodium and heparin lithium have different results on the white blood cell count of the same specimen, and the law of heparin sodium is more obvious, and it can change with time. Hours later, it gradually decreased, and the platelets also gradually decreased. However, heparin lithium is different. The detected white blood cell count and platelet value drop not much, and are relatively slow and stable. In the presentation of the results, the results of heparin sodium and EDTA dipotassium may be similar.
From the above three aspects, we can see the difference between the two, and you should not confuse them in the future. However, in addition to the two anticoagulants of heparin sodium and heparin lithium, the commonly used anticoagulant is EDTA potassium salt , sodium citrate, etc. As an established manufacturer in China, Desheng has a complete range of anticoagulant products and its quality is widely recognized. At present, Desheng has cooperated with many foreign companies. If you have relevant needs, please click the website for consultation!
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