CAS 113274-56-9 Hirudin Blood Clot Activator Active For Prevent Further Blood Stasis

Hirudin Constituents Blood Clot Activator Active For Prevent Further Blood Stasis

Hirudin is one of the most active and studied most active constituents of Leech and its salivary glands. It is a small molecule protein (polypeptide) consisting of 65-66 amino acids. . Otter is rich in hirudin, and hirudin has a strong inhibitory effect on thrombin. It is the strongest natural inhibitor of thrombin found so far. Hirudin has a strong anti-coagulation effect and anti-thrombosis effect, and has broad application prospects in clinical treatment and prevention of various thrombosis.

Usage

Animal experiments and clinical studies have shown that hirudin can effectively anticoagulate, antithrombotic, and prevent further blood stasis caused by thrombin-catalyzed clotting factor activation and platelet response. In addition, it inhibits thrombin-induced proliferation of fibroblasts and thrombin stimulation of endothelial cells. Compared with heparin, it is not only used in a small amount, it does not cause bleeding, and it does not depend on endogenous cofactors. Heparin has the risk of causing bleeding, and antithrombin III is involved in the pathogenesis of disseminated intravascular coagulation. It is often reduced, which will limit the efficacy of heparin, and the use of leeches will have a better effect.

Application

Hirudin is a promising anticoagulant and antispasmodic drug that can be used to treat various thrombotic diseases, especially venous thrombosis and diffuse vascular coagulation. It can also be used to prevent arterial thrombosis after surgery and prevent dissolution. Thrombosis after thrombus or revascularization; improved extracorporeal blood circulation and hemodialysis. In microsurgery, failure often occurs due to vascular embolization at the anastomosis, and hirudin promotes wound healing. Studies have also shown that hirudin can also play a role in cancer treatment. It prevents the metastasis of tumor cells, and has proven therapeutic tumors such as fibrosarcoma, osteosarcoma, angiosarcoma, melanoma and leukemia. Hirudin can also be combined with chemotherapy and radiation therapy to enhance the efficacy of blood flow in the tumor.

Company

Wuhan Desheng Chemical Technology Company was established in April of 2005.Specializing in development,production and sales of IVD chemical reagents.Our product mainly includes Blood collection tube additives,diagnostic kits raw materials,and enhanced chemiluminescent reagents for

AIA.

For more than 14 years,Wuhan Desheng Biochemical Technology operates under the ISO 90001:2008

system and some of our products has been accredited with SGS certification.Having recognized the

significance of accuracy and safety in the pre analytical phase of diagnostics,Wuhan Desheng strongly

contributes towards a responsible IVD chemical reagents provider.Based on strong R&D capacity,

progressive ideas and competency,we strives to manufacture products of uppermost quality at competitive

prices. 50% stuff are bachelor degree,20% are master degree,100% of research and development stuff are master degree.We have built the business relationship with renowned medical apparatus and instruments

firm in domestic market,like improve medical in Guangdong,Zhejiang Gongdong,Zhejiang K.S medical and so

on. What's more,the oversea sales business is expanded to 28 countries in global market.