Sodium Heparin Salt For Extracorporeal Blood , Anti Coagulation Additive For Clinic Blood Test

Blood collection tube additives are an indispensable part of medical blood collection procedures, and heparin sodium anticoagulant is one of the important components. It is a polysaccharide with strong anticoagulant properties that inhibits the coagulation process by binding to clotting factors in the blood. Therefore, it is widely used in blood collection tubes to maintain the original state of blood samples during collection and analysis, in order to avoid errors in results.

The importance of the effective time of heparin sodium anticoagulant

The effective time of heparin sodium anticoagulant in blood collection tube additives is a key factor, which represents how long the initial state of the blood sample can be ensured after adding heparin sodium to the blood collection tube, especially when it is necessary to store the sample for a long time or transfer the sample between multiple laboratories, it can ensure stability within the effective time.

heparin sodium powder

The anticoagulant mechanism of heparin sodium

Understanding the anticoagulant mechanism of heparin sodium is crucial for understanding its effective time. The anticoagulant effect of heparin sodium is based on binding and inhibiting thrombin factor, preventing fibrin formation and thus preventing the coagulation process, achieving anticoagulant goals. It is precisely this effect that makes it an ideal anticoagulant for blood collection vessels. However, its anticoagulant effect is also influenced by some factors, which are also related to its effective time.

Factors affecting the anticoagulant efficacy of heparin sodium

1. The dosage of heparin sodium added is directly related to its anticoagulant efficacy. According to industry standards, the recommended dosage for each milliliter of blood is 12-30IU of heparin sodium. For micro blood collection devices, the dosage should be less than 14IU per milliliter of blood, and adding the dosage may affect anticoagulant efficacy to varying degrees.

2. Concentration: Due to the fact that heparin sodium is in powder form at the factory, it needs to be prepared into a solution of a certain concentration when added to the blood collection tube. Generally, it is calculated as concentration=corresponding weight of heparin sodium/volume of additive (UL), and the concentration also affects its anticoagulant effect.

3. Mixing degree: After adding heparin sodium to the blood collection tube and coming into contact with the blood sample, it is necessary to ensure uniform mixing. Insufficient mixing may lead to local coagulation and reduce the anticoagulant efficacy of heparin sodium.

4. Sample container: The type of blood collection vessel used may also affect the anticoagulant efficacy of heparin sodium. Different types of vessel walls may affect the attachment and release of heparin. It is recommended to use professional heparin tubes.

Practical application

In practical medical practice, the effective time of heparin sodium anticoagulant is usually controlled within a specific time range to meet the needs of different types of laboratories and medical examinations. Generally speaking, the effective time of heparin sodium anticoagulant is 6 hours, and the test should be completed within 6 hours after collecting the blood sample to ensure the accuracy of the results. This is because although heparin sodium has a strong anticoagulant effect, it is a non irreversible anticoagulant that may gradually lose its effectiveness over time, leading to blood sample coagulation.

Product packaging

Heparin sodium anticoagulant plays an important role in blood collection vessels. Understanding its anticoagulant mechanism and effective time is key to reducing experimental interference, saving time for medical staff and patients, and improving disease diagnosis efficiency. As a manufacturer of heparin sodium raw materials, Desheng can supply analytical grade and high-quality products that are easy and fast to use when added to blood collection tubes, with stable performance. If you are interested, please feel free to click on the website for more information and purchase at any time!