Is the biological buffer 2-cyclohexylaminoethanesulfonic acid (CHES) harmful to the human body

In biological and biochemical experiments, 2-cyclohexylaminoethanesulfonic acid (CHES buffer) is a commonly used buffer that plays a crucial role in maintaining pH stability in the experimental environment. However, as people's attention to the safety of chemical substances continues to increase, the question of whether CHES is harmful to human health has also attracted widespread attention.

1, The chemical properties of CHES and the risk of human exposure

CHES is an organic compound with relatively low solubility and high pH stability. In biological experiments, CHES usually exists in the form of powder or solution and enters the human body through direct contact or inhalation. The risk of human exposure to CHES mainly depends on its concentration in the experimental environment, usage methods, and the adoption of personal protective measures.

ches powder

2, Research on the Security of CHES

In order to evaluate whether CHES poses potential hazards to the human body, scientists have conducted a series of studies. These studies mainly focus on the toxicological characteristics of CHES, human exposure levels, and its impact on health.

Toxicological characteristics research: Toxicological research is an important basis for evaluating whether substances are harmful to the human body. Research has shown that CHES is relatively safe under conventional experimental conditions. In animal models, high-dose CHES typically exhibit lower toxicity and are not easily absorbed into the bloodstream. However, individuals with long-term high-dose exposure or special physical conditions may have higher risks.

Research on human exposure levels: The degree of human exposure to CHES mainly depends on the amount used in the experimental operation and the adoption of personal protective measures. By strictly adhering to laboratory safety regulations and taking appropriate personal protective measures, the risk of human exposure to CHES can be effectively reduced.

Research on the impact on health: Current research indicates that under conventional usage conditions, CHES has limited direct impact on human health. However, long-term exposure to high concentrations of CHES or individuals with special physical conditions may pose potential health risks. These risks may include eye irritation, skin allergies, and respiratory system issues.

3, The importance of personal protective measures

It is crucial to take appropriate personal protective measures in order to reduce the risk of human exposure to chemicals such as CHES. Here are some common suggestions for personal protective measures:

Wear appropriate protective clothing: When conducting experiments involving chemicals such as CHES, wear laboratory clothing that meets safety standards and chemical protective goggles. The experimental clothing should be made of materials that have impermeability and do not generate static electricity.

Using respiratory protective equipment: In experimental environments that may produce harmful gases, respiratory protective equipment that meets national standards should be used, such as chemical filter masks or self-contained breathing apparatus.

Product packaging

Ensure that respiratory protective equipment is certified and has filtration capabilities for specific chemical substances.

Follow safety operating procedures: Strictly follow laboratory safety operating procedures and avoid direct contact with chemical substances. Try to minimize the use of high concentrations of CHES and follow the principle of low dose and low exposure in experimental operations.

Regular health check ups: Personnel engaged in experiments involving chemicals such as CHES for a long time should undergo regular health checks to promptly identify potential health issues and take corresponding measures.

Overall, 2-cyclohexylaminoethanesulfonic acid (CHES) is a relatively safe biological buffer under conventional usage conditions, but strict adherence to the instructions is still necessary when using it. Hubei Xindesheng Material Technology Co., Ltd. is a high-quality manufacturer specializing in the research and development, production, and sales of bio buffering agents such as CHES. If you have any purchasing needs, please click on the official website to learn more details!

FAQ

What is CHES buffer used for?

CHES is used as a buffer for studying pH-dependent processes in enzymology. The compound has been shown to have an unusually high affinity for the iodoacetate binding site of liver alcohol dehydrogenase. The compound, which has a has a pKa of 9.49 at 25°C, is useful for the pH 8.6-10.0 range.

What is the solubility of CHES buffer?

CHES is water soluble, non-toxic, and high resolution for solutions.

What is the full form of CHES buffer?

CHES (N-cyclohexyl-2-aminoethanesulfonic acid) is a buffering agent. CHES buffers have a useful range of pH 8.6–10.It typically appears as a white crystalline powder.