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Measures to prevent the insolubility of DIPSO powder 68399-80-4 as a biological buffering agent

Product Details

Place of Origin: hubei

Brand Name: desheng

Certification: ISO9000

Model Number: 68399-80-4

Payment & Shipping Terms

Minimum Order Quantity: 20kg

Price: Detailed discussion

Packaging Details: 20kg / box

Delivery Time: 5 days

Payment Terms: L/C, D/P, T/T, Western Union

Supply Ability: 5t/week

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Specifications
Highlight:

DIPSO reagent

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68399-80-4

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Biological Buffer

Appearance:
White Powder
Model:
DIPSO Buffer
Manufacturer:
Desheng
Packing:
500g / Box
Appearance:
White Powder
Model:
DIPSO Buffer
Manufacturer:
Desheng
Packing:
500g / Box
Description
Measures to prevent the insolubility of DIPSO powder 68399-80-4 as a biological buffering agent

In the fields of biological sciences and pharmaceutical research and development, 3- [N, N-di (hydroxyethyl) amino] -2-hydroxypropanesulfonic acid (DIPSO buffer) plays a crucial role as an efficient and low toxicity biological buffer. Its unique chemical structure endows it with excellent buffering performance and biocompatibility, making it widely used in various processes such as cell culture, protein purification, and biopharmaceutical preparation.

 

Product name 3- [N, N-di (hydroxyethyl) amino] -2-hydroxypropanesulfonic acid Chemical abbreviation DIPSO buffer
Product appearance White crystalline powder CAS NO 68399-80-4
Molecular formula C7H17NO6S Molecular weight 243.28
Density 1.494±0.06 g/cm3(Predicted) Melting point 189-192 °C(lit.)
Storage conditions Sealed and stored away from light at room temperature Packing 500g/bottle
Product advantages High purity, good water solubility Manufacturer Hubei Xindesheng

 

However, DIPSO powder may occasionally encounter issues of insolubility or incomplete dissolution during actual use, which not only affects experimental efficiency but may also lead to deviations in experimental results. This article will delve into the reasons for the insolubility of DIPSO powder and propose a series of effective preventive measures to ensure its smooth application in experiments.

 

Measures to prevent the insolubility of DIPSO powder 68399-80-4 as a biological buffering agent 0

DIPSO powder

 

Analysis of the reasons for the insolubility of DIPSO powder

 

1. Physical state factors: The particle size, shape, and surface properties of DIPSO powder directly affect its dispersion rate and dissolution efficiency in water. Large particles or agglomerated powders, due to their small specific surface area, are difficult for water to quickly penetrate, resulting in slow or even insoluble dissolution.

 

2. Solvent selection and temperature: The properties of the solvent (such as pH value, ionic strength) and temperature have a significant impact on the solubility of DIPSO. The use of inappropriate solvents or low temperatures can increase the difficulty of dissolution.

 

3. Mixing and mixing efficiency: Insufficient mixing or uneven mixing can lead to excessive local concentration, forming a "salting out" effect and hindering further dissolution.

 

4. Storage conditions: Improper storage environment, such as high humidity or large temperature fluctuations, may cause DIPSO powder to absorb moisture and clump, affecting its solubility.

 

Preventive measures: Full chain management from source to application

 

1. Optimize the powder preparation process

 

Refining particles: Advanced crushing techniques such as airflow crushing or ultrasonic treatment are used to refine DIPSO powder to the micrometer or even nanometer level, increasing the specific surface area and accelerating the dissolution process.

 

Surface modification: By surface coating or chemical treatment, the hydrophilicity of the powder is improved, making it easier to interact with water molecules and increasing the dissolution rate.

 

2. Choose the appropriate solvent and adjust the temperature

 

Solvent selection: Prioritize deionized water or buffer solutions with appropriate pH values as solvents, and avoid using solutions containing large amounts of electrolytes to reduce salt precipitation effects.

 

Temperature control: Appropriately increase the dissolution temperature, use thermal energy to accelerate molecular motion, and promote dissolution. However, attention should be paid to avoiding drug denaturation caused by excessive temperature.

 

3. Strengthen mixing and blending strategies

 

Efficient stirring: Use a magnetic stirrer or ultrasonic stirrer to ensure that the solution flows thoroughly and reduce the phenomenon of excessive local concentration. Step by step addition: For large-scale dissolution, DIPSO powder can be added in batches, and each batch should be thoroughly stirred until completely dissolved.

 

4. Improve storage conditions

 

Ensure that DIPSO powder is stored in a dry, cool, and well ventilated environment, using sealed containers to prevent moisture absorption and clumping. Maintain the storage environment temperature within the recommended range, avoid severe fluctuations, and maintain the chemical stability of the powder.

 

Measures to prevent the insolubility of DIPSO powder 68399-80-4 as a biological buffering agent 1

Product packaging

 

Hubei Xindesheng Material Technology Co., Ltd., as a manufacturer of DIPSO and other biological buffer raw materials, has complete after-sales service, can provide good technical guidance, and can track the entire logistics process to protect customer rights. If you have any recent purchasing needs, please click on the official website to learn more details or contact me!

 

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