Home
Products
About Us
Factory Tour
Quality Control
Contact Us
Request A Quote
News
News
Wuhan Desheng Biochemical Technology Co., Ltd
Home ProductsTromethamine

Cas 77-86-1 Ph 7.2 Tris Hcl Buffer In Eye Drops Tris Buffer Solution

China Wuhan Desheng Biochemical Technology Co., Ltd certification
China Wuhan Desheng Biochemical Technology Co., Ltd certification
As a distributor of hospital agent , your Blood Collection Tube Additives is very suit for my needs , i think we have establish a good business with each other , thank you !

—— Tony

I'm Online Chat Now

Cas 77-86-1 Ph 7.2 Tris Hcl Buffer In Eye Drops Tris Buffer Solution

Cas 77-86-1 Ph 7.2 Tris Hcl Buffer In Eye Drops Tris Buffer Solution
Cas 77-86-1 Ph 7.2 Tris Hcl Buffer In Eye Drops Tris Buffer Solution Cas 77-86-1 Ph 7.2 Tris Hcl Buffer In Eye Drops Tris Buffer Solution Cas 77-86-1 Ph 7.2 Tris Hcl Buffer In Eye Drops Tris Buffer Solution Cas 77-86-1 Ph 7.2 Tris Hcl Buffer In Eye Drops Tris Buffer Solution Cas 77-86-1 Ph 7.2 Tris Hcl Buffer In Eye Drops Tris Buffer Solution Cas 77-86-1 Ph 7.2 Tris Hcl Buffer In Eye Drops Tris Buffer Solution Cas 77-86-1 Ph 7.2 Tris Hcl Buffer In Eye Drops Tris Buffer Solution Cas 77-86-1 Ph 7.2 Tris Hcl Buffer In Eye Drops Tris Buffer Solution Cas 77-86-1 Ph 7.2 Tris Hcl Buffer In Eye Drops Tris Buffer Solution

Large Image :  Cas 77-86-1 Ph 7.2 Tris Hcl Buffer In Eye Drops Tris Buffer Solution

Product Details:
Place of Origin: HUBEI,CHINA
Brand Name: DESHENG
Certification: ISO9001
Model Number: TRIS
Payment & Shipping Terms:
Minimum Order Quantity: 500g
Price: Consult the latest quotation
Packaging Details: 500g / bottle, 25kg / barrel
Delivery Time: 5 days
Payment Terms: L/C, D/P, T/T, Western Union
Supply Ability: 100T per month
Detailed Product Description
Name: Tris CAS No.: 77-86-1
Molecular Weight: 121.135 Molecular Formula: C4H11NO3
Appearance: White Crystal Powder Storage Condition: Room Temperature, Light-proof And Moisture-proof
High Light:

CAS 77-86-1 Tris Hcl Buffer

,

PH 7.2 Tris Hcl Buffer

,

PH 7.3 Tris Buffer Solution

What is the role of TRIS in eye drops;CAS 77-86-1;Buffer Solution;White crystal powder

 

What is the role of TRIS in eye drops


TRIS stands for tris(hydroxymethyl)aminomethane, CAS number 77-86-1, appearance is white crystalline powder, good water solubility, compatible with ethyl acetate, not with ether, carbon tetrachloride, for copper Corrosive with aluminum. TRIS is an important organic chemical raw material. In addition to the role we know as a buffer in biochemical experiments, TRIS is also often used in the field of medicine, such as eye drops. As health and safety become more important, there will be some voices questioning whether TRIS is safe for the human body in eye drops, and it spreads in the society. Below we will introduce what role TRIS has in eye drops?

 

Configuration of Tris buffer solution

 

PH value required(25℃) 7.10 7.20 7.30 7.40 7.50 7.60 7.70 7.80 7.90 8.00 8.10 8.20 8.30 8.40 8.50 8.60 8.70 8.80 8.90
0.1mol/L HCI volume 45.7 44.7 43.4 42 40.3 38.5 36.6 34.5 32 29.2 26.2 22.9 19.9 17.2 14.7 12.4 10.3 8.5 7
 

Cas 77-86-1 Ph 7.2 Tris Hcl Buffer In Eye Drops Tris Buffer Solution 0
TRIS has two main functions in eye drops:
1. Adjust the PH value of eye drops
Eye drops are one of the most commonly used drug formulations for ophthalmological diseases. For many eye diseases, eye drops have a direct and rapid therapeutic effect. Due to the special anatomical and physiological characteristics of the eyes, corresponding requirements are put forward for ophthalmic preparations: the pH of normal tears is 7.2 to 7.4, and the range of pH tolerated by normal eyes is 5.0 to 9.0. The pH value of the eye drops will directly affect the eye irritation and the curative effect of the drug. When preparing eye drops, a buffer should be added to adjust the pH of the solution so that it is roughly similar to the tear fluid to reduce the impact on the eyes. Stimulus. At the same time, adjusting the pH value also needs to take into account multiple factors such as drug solubility and stability. TRIS is a commonly used pH regulator in eye drops.
2. As an intermediate of active ingredients.
As an organic amine, TRIS can form a double salt that is easily soluble in water. The most common eye drops containing TRIS are ketorolac tromethamine eye drops. Ketorolac is a non-steroidal anti-inflammatory drug for injection. Ketorolac tromethamine is soluble in water and stable in aqueous solution, with antipyretic, analgesic and anti-inflammatory effects. It reversibly inhibits cyclooxygenase and deoxygenase, thereby inhibiting the biosynthesis of prostaglandins, thereby reducing the response of painful nerves to endogenous inflammatory factors, inhibiting peripheral nerve sensitization, and achieving the purpose of advanced analgesia. Ketorolac tromethamine eye drops are often used for inflammation and pain after eye surgery.
After understanding the role of TRIS in eye drops, it can be found that as a drug that can be used for acute metabolic acidosis and acute respiratory acidosis, TRIS itself can be used in humans. In addition, when we talk about the toxicity of any substance, we can't break away from the dose. As a buffer, there are not many additives, and there will be no safety hazards in normal use. Secondly, animal experiments and clinical studies have shown that ketorolac tromethamine eye drops can significantly reduce corneal sensitivity, have strong analgesic and anti-inflammatory effects, and have no obvious adverse reactions and high safety.
In summary, eye drops containing TRIS are safe. However, although most eye drops are not prescription drugs, in principle, there is no need for regular use of eye drops. If eye discomfort occurs, it is best to seek medical treatment in time. Only when the cause of the disease is identified can the appropriate drugs be selected to relieve the symptoms, achieve the best therapeutic effect, and avoid the harm caused by the wrong drug use.
Hubei Xindesheng Materials specializes in the production and development of biological buffers, blood collection tube additives, chemiluminescence reagents, enzyme preparations, chromogen substrates, carbomers and other products. Desheng was established in 2005. It has an independent R&D team and many years of production experience. The product quality is reliable, the price is favorable, and it can also meet the needs of multiple industries. It has reached long-term cooperation with many companies. If you are interested in understanding Call for consultation, Desheng welcomes your calls.

Cas 77-86-1 Ph 7.2 Tris Hcl Buffer In Eye Drops Tris Buffer Solution 1

Contact Details
Wuhan Desheng Biochemical Technology Co., Ltd

Contact Person: Sales Manager

Tel: +8615071057538

Send your inquiry directly to us (0 / 3000)