Preparation Method Of Blood Coagulant In Blood Collection Tube

The main source of serum samples in current hospitals is to collect venous blood, wait for the blood to completely coagulate and then centrifuge. However, under normal circumstances, the blood after the body needs a long clotting time, so it is difficult to meet the needs of hospitals for rapid testing.

Because hospitals need fast and accurate detection indicators, if the collected blood samples are not processed, it is difficult to meet clinical needs in time, especially for emergency patients, it is more necessary to obtain fast and accurate detection results. The traditional method of promoting blood coagulation is mainly to add kaolin and cephalin to blood samples after collection, which can promote blood coagulation. However, with the advancement of hospital testing methods, blood coagulation accelerators have appeared.

The main function of blood coagulant is to accelerate blood coagulation, that is, to shorten the coagulation time of blood in vitro without affecting the necessary components of blood, and to promote serum separation. The blood coagulant plays such an important role in blood testing, so how is the blood coagulant prepared? There are two methods for reference below.

method one:
A production process of a blood coagulant, including the following steps:
a. Prepare pig brain meal and auxiliary formula with a weight ratio of 1:1.
b. Mix the above two materials evenly.
c. The mixture is sterilized by radiation.
d. Under sterile conditions, place it in a light-proof plastic or glass container and keep it at room temperature.

Method Two:
A preparation method of blood coagulant, which comprises the following steps:
a. Mix the polymer of α-hydrogen-ω-hydroxy (oxy-1,2-ethylenediyl), polyvinylpyrrolidone and isopropanol in proportions, and use a high-shear disperser to mix well until the mixed solution is clear Transparent, and mixed liquid A was obtained.
b. Mix polysorbate, polysorbitol and silica powder according to the ratio, stir, and then homogenize using a high-pressure homogenizer to obtain a mixture B.
c. Mix the mixture A obtained in step a and the mixture B obtained in step b, and shake it up.

As a professional manufacturer of blood collection tube additives, Hubei Xindesheng Material Co., Ltd. has decades of experience in research and development and production, and has a wealth of professional knowledge and capabilities in blood collection tube additives. Internationally, it provides products for many companies. In addition to coagulants, Desheng also produces heparin series, potassium salt series, blood separation gel, sodium citrate and other products. If you have any willingness to cooperate or have questions, please click on the official website of Desheng to contact customer service for consultation. Desheng welcomes your visit.

Advantages of Desheng blood coagulant: