Serum Separation Gel Serum Separating Gel Serum Separator Gel For Blood Collection Tubes

Serum Separation Gel Serum Separating Gel Serum Separator Gel for Blood Collection Tubes

Advantages of Desheng Serum Separating Gel:

Analysis of the components of serum separation

Serum separation gel is a chemically inert and thixotropic viscous colloid. Its density is just between the density of serum and blood clot. After centrifugation, the serum and blood clot can be completely separated. The serum is quickly separated and the material exchange between blood cells and serum is prevented, making blood testing and chemical experiments safer, faster and more convenient.

In this article, the components of the serum separation gel will be analyzed and the performance of the serum separation gel will be compared.

1. Analysis of the components of polysiloxane serum separation gel: The serum separation gel is composed of polysiloxane, silicon dioxide, diluent and additives. The main body material contains 80% to 90% of polysiloxane, 10% to 15% of silicon dioxide, and about 2% of diluents and additives. The appearance of the polysiloxane serum separation gel is a translucent, blue-colored colloid, and the drawing is not long.

2. Analysis of the composition of polyacrylate serum separation gel: The serum separation gel is composed of polyacrylate, fumed silica and additives. The polyacrylate content of the main material is 96%, the fumed silica is 3%, and the additive is 1%. The appearance of polyacrylate serum separating gel is colorless and transparent colloid, with good stringiness.

3. Orthogonal experiments on the components of the serum separation gel show that fumed silica has the greatest influence on the thixotropy and viscosity of the serum separation gel. If the host material can provide hydrogen bonds and the size of the polarity have a certain impact on the thixotropy of the serum separation gel. When the density of the main body material is less than 1g/cm3, the precipitated silica plays a major role in adjusting the density of the serum separation gel. The additive silane coupling agent can fine-tune the thixotropy of the serum separation gel.

The composition of the serum separation gel has a big difference in the effect displayed by the product, and the manufacturer of the serum separation gel can recommend one here. Hubei Xindesheng Material Co., Ltd. has been specialized in the production of serum separation gel for more than ten years. It has rich experience in the development and production of serum separation gel. It has a professional team to manage R&D and production, with excellent product quality and high production efficiency. The warehouse stock is sufficient, and the order will be shipped immediately. If you are interested in Desheng’s products, please enter Desheng’s official website to contact customer service for more information.

The role of separation gel in progesterone detection

What is a separating glue?

Separation gel is a kind of polymer material. Because its density is between serum and (or) plasma and blood cells, it can form a gel barrier between blood clot and serum and (or) plasma after centrifugation, so it can quickly Separate serum and/or plasma from blood. In addition, the separation gel improves the stability of serum analysis, the sample can be transported and stored in the original tube, and can also prevent hemolysis during long-term storage. The separation gel has the risk of adsorption of lipophilic analytes and drugs, and the adsorption effect is related to the contact time and sample volume. In addition, some unstable analytes, such as therapeutic drugs, are not suitable for long-term storage in the separation gel blood collection tube.

Why do progesterone testing?

The detection of progesterone can assist the clinical judgment of ovulation, corpus luteum function and pregnancy, and the accuracy of the results is very important. At present, many clinical laboratories use immunoassay systems to detect progesterone. The instructions clearly indicate that progesterone samples should not be stored in sampling bottles containing gel-type isolates to avoid delayed absorption, and each laboratory is required It is necessary to judge the suitability of the blood collection tubes and serum separation products used by them.

Comparison of two kinds of blood collection tubes for real-time detection of progesterone content

The immediate detection results of serum progesterone in ordinary blood collection tubes were higher than those in separate gel collection tubes. There was no significant difference in the detection results of progesterone between the two blood collection tubes in the low-value group; while the progesterone between the two blood collection tubes in the medium group and the high-value group There are obvious differences in the test results. The serum progesterone content in ordinary blood collection tubes without separation gel is generally higher than that in separation gel collection tubes.

The trend of the detection time of serum progesterone in ordinary serum blood collection tubes

The serum in the ordinary serum collection tube was stored at 2～8℃, and the progesterone test results did not change significantly within 72 hours. The test results showed that the serum was stored in the ordinary serum collection tube at 2～8℃ for 72 hours, the low value group, the median value There was no significant change in the progesterone content of the high-value group and the high-value group over time.

Change trend of serum progesterone detection time in separation gel blood collection tube

The serum in the gel-separated serum collection tube was stored at 2～8℃, and the progesterone test results did not change significantly within 72 hours. The test results showed that the serum was stored in the gel-containing serum collection tube for 72 hours at 2～8℃, low value group The content of progesterone in the middle value group and the high value group did not change significantly over time. However, for pregnant women and patients with high suspicion of high progesterone levels, the type of blood collection tube should be carefully selected, and the clinical reference range of progesterone values ​​should be established for different types of blood collection tubes. For the same patient, the same tube must always be used during the test, and the two blood collection tubes cannot be mixed, so as to avoid large changes in the detection value of progesterone, which will affect the clinical diagnosis.

The performance of serum separation gel:
The principle of serum separation gel: the specific gravity of the separation gel is between 1.045-1.065, and the separation gel has good thixotropy and isolation properties. When the separating gel and coagulated blood are centrifuged in the same test tube, under the action of centrifugal force, the hydrogen bonds between the separating gel molecules are broken and converted into a low-viscosity fluid. Because its specific gravity is between the blood cell and the serum, it is separated during the centrifugation process. The glue edge gradually accumulates between the serum and the blood clot. When the external centrifugal force disappears, the intermolecular hydrogen bonds re-associate to form a network structure, and the separation gel becomes a high-viscosity colloid again, forming a dense isolation layer to separate the serum and blood clots.

The performance of the serum separation gel: The appearance of the separation gel is a colorless transparent colloid with a slight odor, physiologically inert, and insoluble in water. The relative specific gravity of the separating rubber is 1.045-1.065g/cm³, the viscosity is 100,000 to 300,000 centipas, and the volatile content is ≤ 1.5%. Has good thixotropic properties and isolation properties.

Hubei Xindesheng Material Technology Co., Ltd. is a professional manufacturer of serum separation gel in China. It has been engaged in the research and development and production of blood collection tube additives since 2005. It has an experienced R&D team and production team. Obtained the national invention patent certificate.