EDTA K3 Tripotassium Ethylenediaminetetraacetate Acid For Vacuums

Tripotassium ethylenediaminetetraacetate acid EDTA K3 for Vacuums

Tripotassium ethylenediaminetetraacetic acid is a kind of potassium salt of ethylenediaminetetraacetic acid EDTA. It can form superfluous compound with most metal ions and become a general-purpose strong superfluous agent, used for extraction, cation exchange, rare elements Separation, volumetric analysis of calcium, magnesium, and barium, hard water softening, and use as a masking agent, metal cleaning agent, antidote for heavy metal poisoning, and a bactericide.

Physical and chemical properties

The structure of tripotassium ethylenediaminetetraacetate (EDTA-Tripotassium)

High-purity tripotassium ethylenediaminetetraacetate is usually used as an anticoagulant in vacuum blood collection tubes for blood cell analysis. The use of ethylenediaminetetraacetic acid (EDTA) salt as an anticoagulant for blood cell analysis was determined by the International Committee for Blood Standards (ICSH) in 1993 and is widely used.

Using EDTA-K3 anticoagulant blood for blood analysis, there are few reports about EDTA-dependent platelet false reduction. Studies have shown that unexplained low platelet counts are found when using EDTA-K3 anticoagulant blood for blood analysis As a result, the patient should be manually inspected blood slices and PLT manual count review, or the PLT count should be reviewed directly with the instrument for blood cell analysis after dilution with unanticoagulated peripheral blood, in order to correctly understand the patient's true level of PLT. Especially patients with tumors, autoimmune diseases, pulmonary heart disease, pregnant women, advanced liver disease, etc.

In addition to being used as an anticoagulant, tripotassium ethylenediaminetetraacetate is also similar to dipotassium ethylenediaminetetraacetate and disodium EDTA. It can be used with biological buffers such as Tris and MOPS. It can be used as a mask for some divalent metal ions. Agent, complexing agent, etc.

Desheng has been committed to the research of blood collection tube additive separation gel, heparin, and EDTA potassium salt since 2005. Among them, separation gel, EDTA dipotassium, and EDTA tripotassium products are of excellent quality and have stable sales at home and abroad. The difference between tripotassium aminetetraacetate and dipotassium edetate, although the same blood anticoagulant, there are still differences in application.

Uses and preparation methods of ethylenediaminetetraacetic acid (EDTA),EDTA K2/EDTA K3

Ethylenediaminetetraacetic acid, also known as EDTA, belongs to an organic compound. Its appearance is white crystalline powder, odorless and tasteless, with a melting point of 250°C. It is soluble in alkaline solutions such as sodium hydroxide, sodium carbonate and ammonia solution, slightly soluble in water, and insoluble in organic solutions such as ethanol. Ethylenediaminetetraacetic acid is mainly used as disodium salt, and its application fields are many and wide-ranging. Because ethylenediaminetetraacetic acid is a chelating agent that can combine with divalent metal ions such as Mg2+, Ca2+, Mn2+, and Fe2+. Most nucleases and some proteases require Mg2+ to function, so ethylenediaminetetraacetic acid is often used as an inhibitor of nucleases and proteases.

Ethylenediaminetetraacetic acid is also a kind of chelate, which can combine with calcium in the body to form chelated calcium. Therefore, ethylenediaminetetraacetic acid has a lubricating effect, an emulsifying effect and a dissolving effect on the dentin, which is beneficial to the enlargement of the root canal. With years of development, the current technology and level of ethylenediaminetetraacetic acid in root canal treatment have been significantly improved, and ethylenediaminetetraacetic acid has been used more clinically.

Ethylenediaminetetraacetic acid is an important complexing agent. It has a wide range of uses, and can be used as a bleaching and fixing solution for the processing of color photosensitive materials, dyeing aids, fiber processing aids, cosmetic additives, blood anticoagulants, detergents, stabilizers, synthetic rubber polymerization initiators, and ethylenediamine Tetraacetic acid is a representative substance of chelating agents. It can form stable water-soluble complexes with alkali metals, rare earth elements and transition metals. In addition, it can also be used to detoxify harmful radioactive metals from the human body quickly. It is also a water treatment agent. Ethylenediaminetetraacetic acid is also an important indicator, but it is used to titrate metal nickel, copper, etc., when it is used, it must be used with ammonia to act as an indicator.

In addition, the preparation method of ethylenediaminetetraacetic acid is as follows:
Ethylenediamine reacts with formaldehyde and sodium cyanide. Mix 60% ethylenediamine aqueous solution, 30% sodium cyanide aqueous solution and sodium hydroxide, keep at 20℃ and mix for 0.5h. Then the aqueous formaldehyde solution was added dropwise. After the reaction, water was distilled off under reduced pressure. Then repeat the above operation, adding excess formaldehyde for the last time to completely react the sodium cyanide. Adjust the pH to 1.2 with dilute acid. A white precipitate separated out, filtered, washed with water, and dried at 110°C.

Hubei Xindesheng Material Co., Ltd. is a manufacturer of blood collection tube additives. The EDTA-k2/k3/na2 products developed and produced by our company are professional blood anticoagulant products. In addition, our company also produces heparin series and coagulant series , Siliconizing agent series, potassium oxalate and sodium fluoride and other products. Moreover, our company is a professional biochemical reagent manufacturer, and it also has the research and development and production of biological buffers, chemiluminescence reagents, chromogen substrates, enzyme preparations, carbomers and other products. If you are interested in understanding our products, you can enter our official website to contact customer service for more information. Hubei Xindesheng welcomes your visit.

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