EDTA K2 Anticoagulant Raw Material CAS25102-12-9 AR Grade

EDTA K2 Anticoagulant Raw Material CAS25102-12-9 AR Grade

The Chinese name of EDTA K2 is dipotassium ethylenediaminetetraacetic acid. Its appearance is white crystalline powder, tasteless and soluble in water. The pH value of the aqueous solution is about 5.3, and the CAS is 25102-12-9. It is widely used for complexing metal ions and various cleaning products. It is more commonly used as a blood anticoagulant in disposable vacuum blood collection tubes.

Principle of EDTA K2 Anticoagulant

As a chelating agent, EDTA K2 has a greater affinity for calcium ions in the blood, and can effectively chelate and gather them together, so that prothrombin cannot be converted into thrombin, preventing the blood coagulation process at the source. To achieve the purpose of inhibiting the coagulation of blood samples, every 0.8mg can anti-coagulate 1ml of blood. In addition, EDTA K2 is used in vacuum test tubes. After blood collection, it can complex some ions in plasma to make certain types of proteins or nucleic acid substances more stable. However, it is necessary to consider the interference of the formation of complexes on samples or experiments.

EDTA K2 is suitable for clinical routine blood tests, especially platelet counts, but because of its own anticoagulant function, it is not suitable for coagulation images and platelet function tests, nor for determination of calcium ions, potassium ions, sodium ions and other substances.

EDTA K2 parameters:

EDTA K2 for disposable medical vacuum blood collection tube

Under normal circumstances, if 2ml of blood collected in a vacuum blood collection tube, 4 mg of EDTA K2 should be added to prepare the aqueous solution of EDTA K2 for anticoagulation. Since the concentration is too small, in order not to dilute the blood, it is generally used to add 20μl EDTA K2 aqueous solution with concentration of 200g/L in each blood collection tube.Sometimes due to the shelf life and environment of blood collection tubes, water is easy to evaporate on the tube wall, especially plastic test tubes, which may seep through the tube wall and leak out, resulting in the rapid crystallization of EDTA K2 in the tube. In this way, when blood is collected, insufficient anticoagulant blood is likely to occur. Therefore, medical staff are required to slowly turn upside down at least 8 times after blood collection, so that the crystallized EDTA K2 can be fully dissolved and mixed in the blood.

Selection of raw materials for EDTA K2 anticoagulant

EDTA K2 is used to prepare vacuum anticoagulation tubes. The selection of raw materials is extremely important. The purity of main content of EDTA K2 produced by many manufacturers is not high, and the performance is unstable, which interferes with the blood test and affects the process. Therefore, when making a selection, the purchaser can ask the key indicators of the manufacturer EDTA K2 as a reference to avoid raw material quality problems and affect the finished product.

Usage and Dosage

1. Formulated as deionized water solution, and the concentration is determined according to the convenience of the enterprise.

2. General 1.5 ~ 2.2mgedta dipotassium anticoagulation 1mL blood sample. A 2.0 mg anticoagulation 1 ml blood sample is recommended.

Desheng Biochemical has been forging ahead in the research and development and production of EDTA K2 raw materials. Only when the quality is up to standard can it be sold. Therefore, when customers receive EDTA K2, all they bring are good reviews. If you have this demand, please click the website for consultation!