Product Details
Place of Origin: hubei
Brand Name: desheng
Certification: ISO9000
Model Number: AR
Payment & Shipping Terms
Minimum Order Quantity: 500g
Price: Detailed discussion
Packaging Details: 500g/barrel
Delivery Time: 5 days
Payment Terms: L/C, D/P, T/T, Western Union
Supply Ability: 10kg/day
Appearance: |
White Powder |
Model: |
AR |
Manufacturer: |
Desheng |
Packing: |
500g/barrel |
Appearance: |
White Powder |
Model: |
AR |
Manufacturer: |
Desheng |
Packing: |
500g/barrel |
The anticoagulant effect is usually achieved by relying on the substance "heparin", which is then prepared into heparin sodium, which can be used as a blood anticoagulant or as a drug to prevent and treat thrombotic diseases. Clinically, it is highly valued for its strong stability, but sometimes it can lead to serious consequences due to improper use or confusion about the effective form of heparin sodium. Therefore, in order to avoid unnecessary trouble, the following will specifically explore the effective form of heparin sodium.
Heparin sodium parameters:
Appearance | White crystal powder |
Place of Origin | Ezhou City, Hubei Province |
Absorbance | 260nm≤0.10 |
Dissolution | Easily soluble in water |
Titer | 150IU/mg |
Main use | Used as an external anticoagulant for blood |
The mechanism of action of heparin sodium
Due to its strong negative charge, it can bind to antithrombin 3 after contact with blood, thereby inhibiting the reactive coagulation factors and disrupting platelet aggregation, thereby controlling the coagulation process at the source and preventing blood coagulation. From this mechanism of action, it can have the effect of preventing blood clotting both in vivo and in vitro.
Heparin sodium powder
Effective form of heparin sodium
1. Standard heparin sodium
This is a natural polysaccharide extracted from the intestinal mucosa of animals (such as pigs or cows), which is composed of heparin chains of different lengths and has a complex structure. Standard heparin sodium is administered intravenously or subcutaneously and interacts with anticoagulant III in the body to inhibit thrombin activity. The main advantage of standard heparin sodium is its long-term and reversible anticoagulant effect, which is suitable for acute thromboembolism.
2. Low molecular weight heparin sodium
This is a product obtained through enzymatic hydrolysis or chemical means of standard heparin sodium. Compared with standard heparin sodium, low molecular weight heparin sodium has a shorter heparin chain, smaller molecular weight, and more uniform distribution. This form of heparin sodium has a more predictable anticoagulant effect. It does not need frequent laboratory monitoring. It is often used to prevent and treat deep vein thrombosis (DVT) and pulmonary embolism (PE), especially for long-term anticoagulant treatment. It is also widely used in cardiac surgery, orthopedic surgery and thrombosis prevention for high-risk patients. It works in direct contact with the human body in the form of drugs, just like standard heparin sodium.
3. Extracorporeal anticoagulant heparin sodium
This type of heparin sodium is produced through chemical techniques, and its finished product has a powder like appearance, an average molecular weight of around 15000, and a potency between 150IU-180IU. It is mainly prepared into a solution and added to a test tube for use, which has an anticoagulant effect in direct contact with blood, but cannot be injected into the human body. This form of heparin sodium is fundamentally different from the first two forms, and it is important to distinguish its application.
As a professional manufacturer of heparin sodium, Desheng's products are all analytical grade raw materials, usually used as in vitro anticoagulants. For users who want to purchase, they can indicate their usage needs in advance, so that customer service can also provide you with accurate quotations. Interested parties are welcome to contact us at any time!