Comparison Of Blood Anticoagulant Heparin Sodium And EDTA Dipotassium

In clinical medical laboratories, heparin sodium and K2 EDTA are two common Anticoagulant, which are widely used in the collection and preservation of blood samples. They each have unique characteristics and uses, which are crucial for protecting the integrity of cells and molecules in blood samples. What are the differences in their chemical properties, mechanisms of action, and applications in the blood collection process? Let's take a look together.

Heparin sodium parameters:

1, Characteristics and uses of heparin sodium

Heparin sodium is a sulfate polysaccharide Anticoagulant. Its main mechanism is to inhibit the activity of thrombin by combining with coagulation factors, thus preventing blood coagulation. It is usually used for blood sample collection and preservation, and is particularly suitable for clinical testing, blood biochemical analysis, and coagulation function testing. At the same time, it can maintain the integrity of cells in blood samples, effectively prevent coagulation, and maintain stability during the preservation process of blood samples, providing a reliable foundation for subsequent analysis.

Heparin sodium

2, Characteristics and Applications of K2 EDTA

K2 EDTA, also known as Ethylenediaminetetraacetic acid dipotassium salt, is an ideal calcium ion chelating agent. The main function of K2 EDTA is to inhibit the formation of blood thrombin by complexing calcium ions, thereby preventing blood coagulation. K2 EDTA is commonly used for the collection of blood samples, especially for blood routine, blood cell analysis, and blood type identification. It can stabilize cells and cellular components in the blood, prevent coagulation, and ensure that blood samples maintain their original characteristics and structural integrity during storage.

3, Selection and use of heparin sodium and K2 EDTA

When selecting Anticoagulant, it is necessary to decide whether to use heparin sodium or K2 EDTA according to the specific experimental purpose and required analysis items. Heparin sodium is suitable for experiments that require maintaining blood cell integrity, such as blood biochemical analysis and coagulation function measurement, while K2 EDTA is suitable for experiments that require cell stability such as blood routine and blood cell analysis. When using, it is necessary to strictly follow the operating procedures to ensure the correct amount and proportion of Anticoagulant added.

At the same time, the selection of Anticoagulant should also be adjusted according to the type of blood samples and the requirements of analysis items. After collecting blood samples, gently reverse the tube in time to ensure that Anticoagulant is fully mixed to avoid coagulation. In addition, when storing blood samples, attention should be paid to avoiding high or low temperatures and maintaining stable storage conditions to ensure the quality and stability of the samples.

As a professional supplier of blood collection additives, Desheng has always been pursuing product quality and providing reliable reagent raw materials for the market. At present, the purity of K2 EDTA can be as high as 99%. When it is used as Anticoagulant in blood sampling experiment, it is basically free of interference and stable. If you are interested, please feel free to contact us at any time!