Blood Sampling Additive - Blood Anticoagulant

Blood Sampling Additive - Blood Anticoagulant

In the medical field, blood testing is an important means of assessing the health status of patients. In order to obtain accurate blood test results, medical staff need to collect high-quality blood samples. During this process, the additive for blood collection plays a crucial role. Today we will focus on one of the additives for blood sampling - blood anticoagulants.

Powder

1, The principle of action of blood anticoagulants

Blood anticoagulants are chemicals that can prevent blood from clotting. Its main principle of action is to prevent the occurrence of blood coagulation process by inhibiting coagulation factors. Blood coagulation is a complex biochemical process that involves the interaction between multiple coagulation factors. When blood comes into contact with blood vessel walls, platelets activate and release coagulation factors, triggering a coagulation cascade reaction, ultimately leading to the formation of fibrin and blood coagulation. Blood anticoagulants can block certain key steps in this process, thereby prolonging blood coagulation time, maintaining the flow state of blood samples, and facilitating detection and analysis by medical staff.

2, Types and applications of blood anticoagulants

Heparin anticoagulants:Heparin anticoagulants are one of the most widely used anticoagulants in clinical practice, including heparin sodium and heparin lithium. Heparin mainly exerts its anticoagulant effect by enhancing the activity of antithrombin, and is suitable for routine testing in most clinical laboratories. Heparin sodium and heparin lithium have similar principles of action, but lithium ions have a certain impact on platelet function, so in certain specific situations, heparin lithium may be more suitable.

Ethylenediaminetetraacetic acid (EDTA) anticoagulants:Ethylenediaminetetraacetic acid (EDTA) anticoagulants mainly exert anticoagulant effects by chelating calcium ions in the blood. The commonly used EDTA anticoagulants include EDTA-K2, EDTA-K3, and EDTA-Na2. This type of anticoagulant is suitable for blood routine testing, blood type identification, and coagulation function testing. EDTA-K2 and EDTA-K3 have similar principles of action, but potassium ions have a certain impact on platelet function. Therefore, in certain specific situations, choosing different EDTA anticoagulants may be more suitable.

Citrate anticoagulants:Citrate anticoagulants mainly prevent the coagulation process by chelating calcium ions in the blood. Commonly used citrate anticoagulants include sodium citrate, potassium citrate, etc. This type of anticoagulant is mainly used for coagulation function testing, red blood cell sedimentation rate measurement, and platelet function research. It should be noted that citrate anticoagulants have certain effects on the morphology and function of red blood cells, so they are not suitable for certain specific blood testing items.

The anticoagulation principle of different additives:

Advantages and limitations of blood anticoagulants

Advantage:

(1) Maintaining the original properties of blood samples: Blood anticoagulants can effectively prevent the coagulation of blood samples, maintain their flowing state, and facilitate testing and analysis by medical staff.

(2) Extending the storage time of blood samples: Since blood anticoagulants can prevent the occurrence of blood coagulation, they can extend the storage time of blood samples, providing more processing time and flexibility for the laboratory.

(3) Improving the accuracy of test results: Using blood anticoagulants can obtain high-quality blood samples, thereby improving the accuracy of test results.

Limitations:

(1) Impact on specific testing items: Different blood anticoagulants have certain effects on the morphology and function of blood cells such as red blood cells, white blood cells, and platelets, so they are not suitable for certain specific blood testing items. When selecting anticoagulants, it is necessary to evaluate them based on specific testing items and requirements.

(2) Individual differences in patients: There may be differences in the sensitivity of different patients to blood anticoagulants, so in some cases, abnormal coagulation function or other adverse reactions may occur. When using blood anticoagulants, it is necessary to closely monitor and evaluate the patient.

Product packaging

Blood anticoagulants, as a type of additive for blood collection, play a crucial role in the process of blood testing. By selecting and using different types of blood anticoagulants reasonably, it is possible to effectively prevent blood clotting, maintain its flow state, and facilitate testing and analysis by medical staff. Hubei Xindesheng Material Technology Co., Ltd. is the earliest enterprise in China to produce a full range of blood collection additives. The product series is complete, has passed ISO9001, has a research and development team, and the product quality is guaranteed. We welcome inquiries from major blood collection manufacturers!