External use of blood anticoagulants for detecting sodium heparin

Heparin sodium is a natural anticoagulant that mainly exists in the small intestine, liver, and other parts. The heparin sodium currently used on the market is mostly extracted from the intestinal mucosa of pigs. It enhances the activity of antithrombin by binding with antithrombin (AT) and thrombin (IIa), thereby inhibiting the production of thrombin and preventing blood clotting.

The mechanism of action of heparin sodium can be summarized as follows:

Enhancing the activity of antithrombin (AT): antithrombin is an enzyme inhibitor in the blood that can inhibit the activity of thrombin (IIa). However, in the presence of heparin sodium, the activity of antithrombin is enhanced, thereby more effectively inhibiting thrombin.

Inhibition of thrombin (IIa) production: Thrombin (IIa) is a key enzyme in the blood coagulation process. Heparin sodium inhibits the activity of prothrombin and reduces the production of thrombin, thereby preventing blood clotting.

Reduce platelet aggregation: Platelets are a type of cell in the blood that plays an important role in the coagulation process. Heparin sodium can reduce the aggregation ability of platelets, thereby reducing the likelihood of blood clotting.

Heparin sodium powder

The application of heparin sodium in clinical testing

1. Coagulation experiment: In coagulation experiments, sodium heparin can be used as an anticoagulant to collect and process blood samples. It can effectively prevent blood clotting, thereby ensuring the accuracy of experimental results.

2. ESR test: ESR test is an experiment that evaluates the sedimentation rate of red blood cells in the blood. Red blood cells release some biochemical indicators during sedimentation, which can reflect the state of the blood. The use of heparin sodium as an anticoagulant can ensure that red blood cells remain suspended during the experiment, thereby obtaining accurate erythrocyte sedimentation rate results.

3. Blood routine testing: When using heparin sodium as an anticoagulant for blood routine testing, it can effectively prevent blood coagulation and maintain the freshness of blood samples. This helps to obtain accurate cell counts and cell morphology analysis results.

4. Myocardial infarction index detection: In myocardial infarction index detection, heparin sodium can act as an anticoagulant, effectively preventing blood coagulation, thereby ensuring accurate diagnosis and treatment of myocardial infarction by doctors.

5. Blood gas analysis: When heparin sodium is used as an anticoagulant for blood gas analysis, it can effectively prevent blood coagulation and maintain the freshness of the blood sample. This helps to obtain accurate blood gas analysis results to guide doctors in diagnosing and treating respiratory system diseases.

Packaging of heparin sodium

6. Immunological testing: When using heparin sodium as an anticoagulant for immunological testing, it can effectively prevent blood clotting and maintain the freshness of blood samples. This helps to obtain accurate immunological test results to guide doctors in diagnosing and treating immune system diseases.

7. Biochemical testing: When using sodium heparin as an anticoagulant for biochemical testing, it can effectively prevent blood coagulation and maintain the freshness of blood samples. This helps to obtain accurate biochemical test results to guide doctors in diagnosing and treating diseases.

Heparin sodium is an indispensable reagent in blood tests, usually distinguished by green capped blood collection vessels. According to different beliefs, some customers request that heparin sodium be extracted from the small intestine mucosa or viscera of sheep. Hubei Xindesheng Material Technology Co., Ltd. is a professional manufacturer of research and development and production of blood collection additives. We can customize products to meet the different needs of our customers. If you are interested, please click to browse the website for more details!