| Product Name | Sodium citrate |
| CAS number | 6132-04-3 |
| Product performance | White crystal powder, easy to absorb moisture |
| Product Usage | Blood anticoagulants, used for coagulation function testing and erythrocyte sedimentation rate measurement |
| Save Method | Sealed and moisture-proof, avoiding direct sunlight |
| Validity period | 3 years |
| Origin | Ezhou City, Hubei Province |
Calcium ions play a crucial role in the process of blood coagulation. It is involved in multiple coagulation processes such as activation of thrombin and platelet aggregation. Therefore, when citrate ions bind with calcium ions, the coagulation process is significantly inhibited, thereby achieving the goal of anticoagulation.
Sodium citrate powder
2, The application of sodium citrate in blood coagulation detection
Blood coagulation testing is an important means of evaluating the coagulation function of patients, and is of great significance for diagnosing hemorrhagic diseases, thrombotic diseases, and other related conditions. The blood collection vessels used for coagulation function testing are blue caps, and the concentration of sodium citrate in these blood collection vessels is usually set at 3.2% or 3.8%, which is 0.109mol/L or 0.129mol/L. When using this blood collection method, the ratio of sodium citrate to the blood sample is controlled at 1:9 to ensure anticoagulant effect without affecting other properties of the blood sample.
When blood samples are collected into these blood collection vessels, sodium citrate quickly binds with calcium ions in the blood to prevent blood clotting. Subsequently, these anticoagulated blood samples can be separated from the bleeding plasma by centrifugation and other methods for subsequent coagulation index detection.
3, The application of sodium citrate in erythrocyte sedimentation rate detection
ESR detection is a commonly used clinical examination method to evaluate the sedimentation rate of red blood cells and determine whether there are pathological changes such as inflammation and infection in the body. The brown cap vacuum blood collection tube is used to measure erythrocyte sedimentation rate. The concentration of sodium citrate in this blood collection tube is 3.2%, equivalent to 0.109mol/L. In this type of blood collection, the ratio of sodium citrate to blood is adjusted to 1:4 to ensure anticoagulant effect without affecting the sedimentation rate of red blood cells. When blood samples are mixed with sodium citrate, red blood cells remain in a dispersed state under anticoagulation, which can more accurately reflect their sedimentation rate.
4, Precautions for using sodium citrate anticoagulant tubes
After collecting blood samples, when using vacuum blood collection vessels containing sodium citrate, medical personnel need to gently invert the blood sample and anticoagulant thoroughly to ensure that the anticoagulant can be quickly and evenly dispersed in the blood, effectively preventing blood coagulation. If it is a erythrocyte sedimentation rate test, the sample can be directly placed on the erythrocyte sedimentation rate rack for observation; If it is a blood coagulation test, the bleeding plasma needs to be separated by a centrifuge for further analysis.
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Hubei Xindesheng Material Technology Co., Ltd. has been specializing in the research and development, production, and sales of blood vessel additives for nineteen years, with a strong research and development background and professional technical personnel. At present, the additives for blood collection on sale include serum separation gel, various types of anticoagulants, coagulants, silicides, etc., which have been sold to many regions both domestically and internationally, and have received high praise from many customers. If you are also interested, click on the official website to search!