CAS 35556-70-8 High Purity White Biological Buffer PEP Powder

Molecular structure

Advantage

The purity is >99%, with good water solubility and stable process, which can ensure that the product appearance is pure white crystal powder.

Phosphoenolpyruvate (PEP) is a glycolytic metabolite with high-energy phosphate group. PEP (0.1-10 mm) significantly reduced the decrease of cell viability induced by hydrogen peroxide (H (2) O (2)) in HeLa cells in a dose-dependent manner. PEP also inhibited the decrease of cells stained with calcein acetomethoxy and the increase of cells stained with propidium iodide induced by H (2) O (2). 

PEP is a functional carbohydrate metabolite with cell protection and antioxidant activity, and may be used as a therapeutic agent for diseases involving oxidative stress. However, there was no effect at low dose (0.1, 1 mm). PEP (0.1-10 mm) also reduced cell damage, but did not decrease the intracellular ATP content induced by glycolysis inhibitor 2-deoxy-D-glucose.

PEP also reduced the leakage of aminotransferase and LDH during 72 h organ preservation, histological changes and oxidative stress parameters (measured by thiobarbituric acid reactive substances and glutathione content). The effect is comparable to that of the University of Wisconsin solution, a gold standard organ preservation agent. PEP treatment can reduce the decrease of ATP content in liver during cold storage. 

Product quality and customer service of product buffer PEP produced by Desheng have been recognized by many customers and established as long-term suppliers.

Desheng is a chemical reagent company specializing in blood test reagents with 14 years of R&D experience, especially has a deep research on chromogenic substrate and biological buffer. Enterprises or individuals in need can directly contact 15071057538(Wechat is the same number) . We look forward to your calls, to join hands in creating a better tomorrow!