China Wuhan Desheng Biochemical Technology Co., Ltd Company News

Heparin sodium, as a commonly used anticoagulant, is often added to blood collection vessels to ensure that blood remains in a liquid state during collection, transportation, and analysis, preventing coagulation. This additive with bioactive molecules requires a specific concentration of solution to ensure the anticoagulant effect in the test tube. However, as the original form of heparin sodium is powder, it needs to be prepared into a solution in advance before use, and there are certain requirements for its solubility. Therefore, let's take a look at the solubility of heparin sodium together.   Heparin sodium powder   Solubility of heparin sodium   The raw material of heparin sodium is powder, which has a certain solubility in water. Its solubility is often expressed as a percentage, in the form of w/v (mass/concentration). Normally, a 5% (W/V; 5g/100ml) heparin sodium solution is clear, which means that every 100 milliliters of solution contains 5 grams of heparin sodium. This concentration is sufficient to provide the required anticoagulant effect in the blood collection vessel, but sometimes it may be adjusted according to the needs of the enterprise.   Factors limiting the dissolution of heparin sodium   The dissolution of heparin sodium is sometimes influenced by factors such as temperature, pH value, and ion strength. Under normal room temperature conditions, powder is easily soluble, but under extreme conditions such as high or low temperatures, its solubility is limited. In addition, the pH value of heparin sodium in a 1% (W/V; 1g/100ml) pure water solution is between 6.0 and 8.0. If the dissolution pH value is too high, it will also cause changes.   Usage and dosage of heparin sodium in blood vessels   1. Solution preparation: In order to add heparin sodium to the blood collection vessel, it is first necessary to prepare a suitable concentration of heparin sodium solution. Usually, a ratio of 1:100 is used, which involves adding 1g of heparin sodium to 100g of deionized water, but this is not fixed and can be adjusted according to usage requirements.   2. Dosage selection: The dosage of heparin anticoagulation is usually determined based on the specific needs of experiments or blood collection. Generally speaking, the recommended range for heparin anticoagulation is 9.4-28IU/ml blood sample. According to the volume of the blood sample and the required degree of anticoagulation, an appropriate dosage of heparin sodium can be selected. For example, usually 20 IU of heparin anticoagulant 1 mL of blood sample is selected, or the dosage of 0.1 mg of heparin anticoagulant 1 mL of blood sample is prepared.   Heparin sodium is a commonly used additive in blood collection, and a thorough understanding of its solubility and dosage is of great help in ensuring experimental results. As an advantageous manufacturer of heparin sodium, Desheng can provide raw material powders with good solubility and cheap prices, as well as technical guidance and instructions, effectively solving customer usage problems. If you have any interest, please feel free to contact us for purchase!

Heparin Sodium, also known as Heparin Sodium, is a common reagent that can be used as an in vitro anticoagulant or as an anticoagulant drug. As a sulfated polysaccharide, it plays an important role in the medical field, especially in preventing blood clotting. Below is a specific introduction to heparin sodium solution.   Nature and characteristics   The "heparin" in heparin sodium is a sulfated polysaccharide compound extracted from pig intestinal mucosa or bovine lung mucosa, which belongs to natural polysaccharide drugs. Its chemical structure contains multiple sugar chains, which carry negative charges, giving heparin strong anticoagulant ability. In vitro, due to its good solubility in deionized water, it is prepared into a solution and added to a test tube. After anticoagulation treatment of blood samples, it is suitable for various biochemical tests, such as liver and kidney function testing.   Preparation of heparin sodium solution   Before starting to prepare heparin sodium solution, the following tools and materials need to be prepared: electronic balance, volumetric flask, beaker, deionized water, glass rod, and washing bottle. Before operation, it is essential to maintain a clean working environment to avoid contamination of the solution with impurities, bacteria, etc.   1. Weighing heparin sodium: Use an electronic balance to accurately weigh the required proportion of heparin sodium raw powder. Due to the usually small dosage of heparin sodium, it is necessary to ensure that the weighing accuracy reaches 1/10000 to ensure the concentration and effectiveness of the subsequent solution.   2. Dissolve heparin sodium powder: Add the weighed heparin sodium powder to a beaker, and then add a certain amount of deionized water. Stir thoroughly with a glass rod until completely dissolved, paying attention to controlling the amount of deionized water added.   3. Transfer to a volumetric flask: Transfer the dissolved heparin sodium solution to the volumetric flask, paying attention to keeping the opening of the volumetric flask parallel to the eyes during the transfer process to avoid liquid errors.   4. Constant volume: After all the solution is dissolved, wait until the solution reaches the mark on the volumetric flask. During this process, pay attention to keeping the mark on the same level as the liquid level.   5. Mix well: Seal the volumetric flask and thoroughly invert to ensure the uniformity of the heparin sodium solution.   6. Check and confirm: Carefully check the weight of heparin sodium, volumetric flask volume, and other factors, and perform corresponding calculations to confirm the effective content and concentration of heparin sodium solution.   Preservation of heparin sodium solution   Normally, the prepared heparin sodium solution should be stored in a low-temperature environment of 0-4 ℃, which can help prolong the stability and effectiveness of the solution. At the same time, pay attention to the sealing of the storage container to prevent external air and pollutants from entering the solution, and maintain the solution free of impurities. The suggestion is to use it immediately, and if it is necessary to store it, it should not exceed one week.   Desheng, as an advantageous manufacturer of additives for blood collection, can provide raw material powders with high main content and stable performance. It is easy to prepare, can be operated in batches, and is convenient for storage and transportation, with satisfactory prices. If you have any interest, please feel free to contact us for purchase!

Heparin sodium, as an important anticoagulant, is widely used in clinical and laboratory fields. Its superior anticoagulant performance makes it an indispensable reagent in the blood collection process. Due to the widespread clinical use and the fact that the production of heparin sodium is not a simple process, professional technology and equipment are required to ensure the quality and stability of the product. Suppliers, on the other hand, serve as a bridge between producers and users, and their role in the manufacturing process cannot be ignored.   In order to ensure the stability of product use, when selecting a supplier of heparin sodium raw materials, the following points should be noted:   1. Quality certification and compliance: Select suppliers with ISO quality certification to ensure that their production processes meet quality standards. At the same time, suppliers should comply with the regulatory requirements of relevant production institutions to ensure the safety and compliance of their products.   2. Production capacity: The production capacity of the supplier should match the demand to ensure timely provision of the required heparin sodium raw materials, and to avoid losses caused by customer shortages and delayed production due to insufficient production capacity.   3. Quality control: Suppliers should have a strict quality control system, including the procurement, production, testing, and storage of raw materials, to ensure the stability and consistency of products. In addition, professional personnel can be equipped to monitor products in a timely manner, conduct repeated inspections, and strictly control production parameter standards.   4. Technical Support: Suppliers should provide professional technical support, including guidance on product properties, application methods, and other aspects, to help customers better use heparin sodium raw materials.   5. Supply stability: Suppliers should have stable supply capabilities to ensure their willingness to achieve long-term cooperation with customers. This can not only save customers time and money costs, but also enable suppliers to continuously and steadily generate profits.   Suppliers of heparin sodium raw materials play a crucial role in the medical field. By providing high-quality heparin sodium raw materials, they help clinical patients efficiently process blood and detect it in a timely manner. This not only saves medical staff time, but also facilitates the treatment of patients' conditions. However, it should be noted that suppliers must be carefully examined from the above five aspects in order to ensure the reliable quality of raw materials. Here, we recommend Desheng to everyone.Desheng specializes in producing blood collection additives,as it is directly sold by manufacturers, it not only has a large warehouse reserve and stable supply, but also is equipped with professional one-on-one guidance to ensure worry free use of heparin sodium raw materials. If you have any interest, please feel free to contact us for purchase!

Heparin, as an important anticoagulant, plays an indispensable role in medical and laboratory applications. Its anticoagulant effect is strong, and heparin sodium and heparin lithium, as common binding forms, have unique advantages, making them one of the highly respected choices in blood collection additives.   1、 Heparin anticoagulant effect   Heparin plays a significant role in anticoagulation, starting from enhancing the affinity between antithrombin 3 and thrombin, accelerating the inactivation of thrombin, and inhibiting platelet adhesion and aggregation. It can enhance the activity of protein C and stimulate the release of anticoagulant and fibrinolytic substances from vascular endothelial cells. Heparin exhibits multiple anticoagulant properties, and both heparin sodium and heparin lithium possess these anticoagulant properties.   2、 Clinical application of heparin sodium and heparin lithium   Heparin sodium and heparin lithium are important substances in anticoagulant blood vessels, and processed blood samples can be used to measure pH and electrolytes. At the same time, due to the addition of heparin, the anticoagulant enzyme in the blood collection vessel prolongs the clotting time of the sample, and is also suitable for projects such as red blood cell fragility test, blood gas analysis, red blood cell compression test, erythrocyte sedimentation rate and universal biochemical determination. However, it should be noted that heparin is not suitable for blood coagulation experiments, as excessive heparin can cause significant changes in white blood cells and interfere with accurate counting.   3、 Selection of heparin sodium and heparin lithium   The two common binding forms of heparin, heparin sodium and heparin lithium, may be confusing in their selection. Although they are all binding forms of heparin, there are significant differences in their effective ion binding, resulting in significant differences in the degree of dissociation. Although experimental comparisons have shown that heparin lithium is slightly better than heparin sodium in terms of efficacy, the dosage used in vacuum blood collection also varies. But in fact, their use is based on experimental requirements, and their anticoagulant effects are consistent, and they can both exert stable performance in clinical practice.   So from the above, it can be seen that the heparin sodium and heparin lithium in the additive for blood collection are both good and play irreplaceable roles in medical diagnosis and laboratory testing. Their advantages make them the preferred choice in many medical and laboratory fields. As an advantageous supplier of heparin sodium and heparin lithium, Desheng can provide raw material powders with low impurities and excellent anticoagulant effects, which are ready to use and convenient for storage and transportation at a competitive price. If you have any interest, please feel free to contact us for purchase!

Heparin sodium, as a commonly used anticoagulant for blood collection, plays an important role in medical and laboratory research. However, some key issues need to be noted when using heparin sodium to ensure its effectiveness and safety. Let's take a look at the issues to pay attention to when using heparin sodium.   1. Selection of dosage: The dosage of heparin sodium should be determined based on the specific situation and purpose. Different biochemical projects may require different levels of heparin sodium. For example, the recommended dose range for conventional test tubes is 12-30IU of heparin sodium per milliliter of blood, and the anticoagulation of micro blood collectors can be less than 14IU per milliliter of blood. Therefore, suitable heparin sodium test tubes should be selected for blood collection based on the examination items before use.   2. Preparation and storage: Heparin sodium is generally supplied in the form of raw powder, and appropriate preparation and dissolution are required before use. Generally, deionized water can be used for dissolution. It is important to follow the recommendations in the product manual during the preparation process to ensure that the concentration of dissolved heparin sodium meets experimental or clinical requirements. The prepared heparin sodium solution should be added in a timely manner. If it needs to be placed, it should be stored in a sterile environment at 0-4 ℃ as much as possible. The addition should be completed within a week, avoiding direct sunlight to maintain its stability.   3. Addition method: Generally, the addition method is divided into machine and manual methods. Regardless of which method is used, attention should be paid to completing it in a sterile state. If using a machine, it is necessary to clean its conveying pipeline and container, and disinfect and air dry it with alcohol to ensure that there are no impurities, bacteria, or scale attached to the pipe wall.   4. Inverted mixing: To ensure sufficient anticoagulation effect on blood, the test tube should be inverted and mixed as soon as possible after blood collection, especially when the temperature of the blood collection environment is too high. If not inverted in a timely manner, it may cause abnormal test results.   5. Timely testing: Pay attention to completing the test within 6 hours, as heparin is a non irreversible anticoagulant. If the test is not completed within the specified time, it is prone to result errors.   In summary, as an important anticoagulant for blood collection, heparin sodium needs to be used with caution and follow professional advice. Reasonable dosage and correct usage methods will help ensure the effectiveness and safety of heparin sodium, thus providing reliable support for clinical and laboratory research.   As a supplier of heparin sodium raw materials, Desheng not only provides high-quality products, but also can customize production according to customers' specific needs to meet the requirements of different experiments, while paying attention to providing comprehensive after-sales service. If you have any interest, please feel free to contact us for purchase!

Heparin Sodium is a common anticoagulant for blood collection, widely used in clinical medicine and biochemistry. Its unique anticoagulant effect makes it a key component in blood collection and laboratory analysis, and the use of heparin sodium plays an important role in multiple fields such as medicine, research, and laboratory.   1、 Blood collection   Heparin sodium is widely used in blood collection processes, especially when it is necessary to preserve blood samples. It inhibits the activation of coagulation factors and prevents blood from clotting in pipelines or containers. Because during the blood collection process, blood is extracted into blood collection vessels containing heparin sodium, which quickly reacts with thrombin in the blood to prevent blood clotting and ensure that the collected blood samples remain in a liquid state, providing accurate data for subsequent analysis.   2、 Hemodialysis and renal dialysis   Heparin sodium is also widely used in treatment processes such as hemodialysis and kidney dialysis. In these treatments, blood is filtered and purified through machines, and this process requires maintaining blood fluidity to avoid coagulation. The anticoagulant effect of heparin sodium helps to maintain blood flow and facilitate the smooth progress of the treatment process.   3、 Laboratory analysis   Heparin sodium also plays an important role in laboratory analysis. Many biochemical and molecular biology experiments require the use of blood samples for analysis, such as determining various components, proteins, and nucleic acids in the blood. Heparin sodium can prevent blood clotting and keep the sample in a liquid state during the experimental process, thus obtaining accurate experimental results.   4、 Research field   Heparin sodium is not only widely used in clinical medicine, but also plays an important role in scientific research. In many biological studies, anticoagulation treatment of blood samples is necessary for various experiments and observations. Heparin sodium can play an anticoagulant role during the experimental process, ensuring normal blood circulation and providing a reliable foundation for research.   Heparin sodium has a wide range of applications in various fields such as medicine, laboratory analysis, and research. Its anticoagulant properties make it an important tool for protecting blood from coagulation, ensuring the smooth progress of blood samples and biochemical treatment projects. As a raw material manufacturer of heparin sodium, Desheng can provide white powder with high main content, convenient storage, simple preparation, stable anticoagulant effect, and low price. If you have any interest, please feel free to contact us for purchase!

With the continuous development of medical technology and the widespread promotion of clinical applications, heparin sodium, as an important anticoagulant, can be added to blood collection vessels or prepared into drugs for use in fields such as cardiac surgery, hemodialysis, and intravascular therapy. However, the accompanying issue is the price of heparin sodium, which cannot be ignored in the market and involves the production cost of the company. The following will delve into the factors behind the price of heparin sodium and their impact.   Factors Influencing the Price of Heparin Sodium   1. Production cost: The preparation process of heparin sodium is relatively complex, involving multiple chemical synthesis steps and purification processes. The raw materials, instruments and equipment required in the production process will directly affect the production cost of the product, thereby affecting the final price setting.   2. Raw material price: Its preparation requires a series of raw materials, including organic compounds, pig small intestine, etc. The market price fluctuations of these raw materials will directly affect the production cost of heparin sodium, thereby affecting the price of the product.   3. Quality standards: High purity heparin sodium often requires strict quality control and testing, which involves more testing equipment and labor costs. Therefore, different quality standards require different production costs, which can also affect the final price.   4. Market competition: The market competition for heparin sodium is fierce, and competition between different manufacturers may lead to price fluctuations and decreases, which can also have an impact on product prices.   Changes in the price of heparin sodium   The price of heparin sodium is influenced by various factors such as market supply and demand, raw material prices, and medical demand, so it may fluctuate over a certain period of time. In addition, changes in the global market and adjustments in international policies will also have an impact on its prices.   Consideration of price rationality   When setting prices, in addition to considering production costs, it is also necessary to consider the rationality of the price. Price is not only related to the operational status of the production enterprise, but also to the rights and interests of users. A reasonable price should not only meet the reasonable profit of the production enterprise, but also fully consider the market's affordability.   Heparin sodium, as an indispensable reagent, has great significance in the medical field. Its price is influenced by various factors, including production costs, raw material prices, quality standards, and market competition. A reasonable price can not only reflect the value of the enterprise, but also protect the rights and interests of customers. As a manufacturer of heparin sodium, Desheng can provide affordable raw materials with excellent production and stable performance, which have been praised by manufacturers who have used it. If you are interested, you can also contact us to purchase!

Heparin Sodium is a commonly used anticoagulant widely used in clinical medicine and laboratory research. It can not only be prepared into drugs to prevent the formation of blood clots, but also effectively inhibit blood coagulation in blood collection vessels. Blood samples treated with anticoagulation are suitable for various biochemical items. However, in addition to synthetic heparin sodium, there is also a natural source of heparin sodium, which is extracted from pigs. This article will introduce the characteristics and preparation process of heparin sodium extracted from pigs.   characteristic   The heparin sodium extracted from pigs is extracted from the intestinal mucosa of pigs. Compared with synthetic heparin sodium, it has the characteristics of naturalness and diversity. In the early stage, heparin was extracted from animal livers, but it was later discovered to exist in the small intestine of pigs. In addition, China's pig farming industry is developed, and it is naturally obtained from pig intestines, which is a natural source of anticoagulants. This also makes it more popular in certain specific application fields. Diversity indicates that there may be slight structural differences in heparin sodium from different sources, which may lead to different biological activities and bioavailability of heparin sodium extracted from pigs in certain situatio.   Preparation process   The preparation process of heparin sodium extracted from pigs involves multiple steps and techniques to ensure the production of high-purity heparin sodium products. The approximate steps are as follows:   1. Raw material processing: Firstly, extract the precursor substance of heparin sodium from fresh small intestine. After careful cleaning of the small intestine, the mucosa is scraped off and crushed into fragments, preparing for the subsequent steps.   2. Heating enzymatic hydrolysis: The chymosis mucosa is placed in a heating tank, with an appropriate amount of water added, followed by approximately 8% trypsin. Next, by gradually adding a weak alkaline solution, the pH of the solution is maintained between 8 and 10. The temperature gradually increases, first heating to 30-40 ℃, holding at this temperature for 2-3 hours, then heating to 50-60 ℃, holding for 10-20 minutes. The entire process requires maintaining the pH of the solution between 8.5 and 9.5.   3. Cooling adsorption: The solution after enzymatic hydrolysis is cooled to 30-40 ℃ and the surface oil is removed. Then, add the resin to the solution and stir for 6-7 hours to achieve the adsorption of heparin sodium. After adsorption, the resin is filtered out, carrying heparin sodium.   4. Elution: By adding a 10% mass fraction of sodium chloride solution, the adsorbents on the resin are eluted. This process is carried out at 50-55 ℃ and stirred continuously for 3-4 hours to ensure complete elution of heparin sodium from the resin. This step was repeated twice, and the two eluents were merged.   5. Sedimentation: The combined eluent is filtered and transferred to the sedimentation tank. Adjust the pH of the solution to 7-8 while adding 80-85% alcohol. Next, the solution is sealed for 10-12 hours to promote the formation of heparin sodium precipitate, which is then filtered out.   6. Dehydration and drying: The filtered sediment is placed in a drying oven for dehydration and drying. After this step, a high-purity pig extracted heparin sodium product was ultimately obtained.   Through the above preparation process, heparin sodium extracted from pigs was successfully prepared, and each step in this process requires strict control of conditions to ensure the final product quality. As a manufacturer of heparin sodium, Desheng can provide high content raw material powder, which is convenient and simple to use. When added to blood vessels for in vitro anticoagulation, its performance is stable. If you are interested, please feel free to contact us at any time!

Blood collection is a common operation in clinical diagnosis and laboratory testing. To ensure that the collected blood samples accurately reflect the biochemical status of the body, appropriate anticoagulants need to be used to prevent blood coagulation. Heparin lithium, as a commonly used anticoagulant for blood collection, is widely used in clinical and laboratory settings. Below, we will explore the usage and precautions of heparin lithium as an anticoagulant for blood collection. Let's take a look together.   The mechanism of action of heparin lithium   Heparin lithium is a natural polysaccharide that primarily inhibits the activity of thrombin, thereby preventing the coagulation process. It can bind to antithrombin III, thereby inhibiting the formation of thrombin and inhibiting the coagulation cascade reaction. At the same time, it can also inhibit platelet aggregation by binding to coagulation factors on the surface of platelets.   Method of using heparin lithium as an anticoagulant for blood collection   Heparin lithium is usually injected into the blood collection vessel in the form of a solution to come into contact with the blood and achieve anticoagulant effects. When using heparin lithium, the following aspects need to be noted:   1. Appropriate concentration: The concentration of heparin lithium needs to be determined based on specific circumstances. Usually, in medical practice, the appropriate concentration of heparin lithium is determined based on the size of the blood collection vessel and the amount of blood required to be collected. The recommended amount for general industry standards is 9.4IU-28IU of heparin lithium per milliliter of blood. If using a peripheral blood sampler, anticoagulation needs to be less than 14IU per milliliter of blood.   2. Uniform mixing: Before using heparin lithium solution, it is necessary to thoroughly mix it evenly to ensure that heparin lithium is evenly distributed in the solution and ensure its anticoagulant effect is consistent.   3. Adding technique: When adding and preparing heparin lithium solution, it is generally divided into manual and machine adding. Machine adding requires setting machine parameters and paying attention to cleaning the pipeline to avoid impurities or bacterial residues. At the same time, it is necessary to timely check whether the dosage of the addition meets the requirements to ensure that the anticoagulant effect reaches the ideal state.   Matters needing attention   1. To ensure sufficient anticoagulation of blood samples, medical staff should invert and mix them as soon as possible after blood collection, without using excessive force, just gently invert 5 to 8 times.   2. The heparin lithium anticoagulant tube should be tested within 6 hours as much as possible, as it is a non irreversible anticoagulant. If not tested for a long time, it may lead to deviation in the test results.   3. Heparin is sensitive to indicators such as AST, ALT, and TBIL. It can participate in the metabolism of cellular enzymes and ions, and its usage may affect the detection results. Therefore, it is important to pay attention to the amount of heparin lithium tubes added during the detection project and select appropriate heparin lithium tubes according to different projects.   As an additive for blood collection, heparin lithium can effectively prevent blood coagulation during the blood collection process by inhibiting thrombin activity and reducing platelet aggregation, ensuring the quality of collected blood samples. Through scientific and reasonable use, heparin lithium will better exert its anticoagulant effect during blood collection, ensuring the accuracy of clinical diagnosis and laboratory testing.   As a manufacturer of heparin lithium, Desheng can provide raw material powder for manufacturers to prepare and add, with high main content and stable performance. 80% of test tube manufacturers will choose to cooperate with us. If you are also interested, please feel free to contact us at any time!

Heparin Sodium, is an important anticoagulant widely used in the medical field. It is a polysaccharide compound composed of heparin sulfate. Due to its excellent anticoagulant effect, it is widely used in clinical practice to collect blood vessels or prepare drugs to prevent and treat thrombosis and other coagulation related diseases. The following will analyze the chemical properties, structure, and use of heparin sodium.   Chemical properties and structure   Heparin sodium is a natural polysaccharide, mainly composed of heparin sulfate. Heparin sulfate is a polymer composed of various amino sugars such as glucosamine and arginine. It contains a large number of sulfate groups, which endow heparin sodium with strong anticoagulant effects. Its chemical structure is complex, with different molecular weights of heparin sulfate ranging from thousands to hundreds of thousands. For example, the average molecular weight of heparin sodium, a blood vessel anticoagulant, is around 15000, while the drug heparin sodium is around 5000.   The use of heparin sodium   1. Anticoagulant therapy: Heparin sodium, as an effective anticoagulant, is commonly used to prevent and treat thrombosis, especially in postoperative and severely traumatic patients. It can prevent the activation of coagulation factors and platelet aggregation, thereby preventing the formation of thrombosis.   2. Hemodialysis: It is widely used in the process of hemodialysis to prevent blood clotting within the dialysis device through anticoagulation.   3. Heart surgery: In heart surgery, heparin sodium is commonly used to prevent intraoperative blood clotting and maintain blood flow. In special circumstances, such as high-risk diseases or surgeries, heparin sodium can be used to prevent the occurrence of blood clotting.   4. Endovascular therapy: In interventional endovascular therapy, heparin sodium can prevent instruments such as catheters and stents from forming blood clots in the blood vessels.   5. In blood collection vessels: used for anticoagulation treatment of blood, often in the form of raw powder on the market. When used, it needs to be prepared into a solution and added to a test tube to keep the blood sample in its original flow state, which is conducive to various biochemical tests, such as liver and kidney function testing.   Precautions for use   1. Dose adjustment: The dosage of the drug heparin sodium needs to be adjusted according to the patient's condition and use to ensure its anticoagulant effect and safety. The amount of heparin sodium added to the blood collection vessel needs to be according to the standard amount, such as adding 12-30IU of heparin sodium per milliliter of blood.   2. Anticoagulant monitoring: When using the drug heparin sodium, it is necessary to regularly monitor the patient's coagulation indicators to ensure that the anticoagulant effect is within a safe range.   3. Attention time: Heparin anticoagulation is non irreversible, so the heparin sodium anticoagulant tube should be tested within 6 hours after blood collection, otherwise it may cause problems in the test results.   Heparin sodium, as an important anticoagulant, plays an important role in the medical field. Although heparin sodium has broad application prospects, caution should also be taken when using it, and it is recommended to choose a supplier with reliable quality. As one of the suppliers of heparin sodium, Desheng can provide stable raw material powder for anticoagulation in blood collection, which is not suitable for disease treatment. It should be clear that the purpose can be explained in advance when purchasing, making it easier to quote. Welcome to click on the website to inquire about details!

Heparin is a commonly used anticoagulant, widely used in clinical medicine and biochemical experiments. Among them, heparin lithium and heparin sodium are the two most common heparin anticoagulants, with slight differences in structure and application. The following will compare and analyze these two types of heparin anticoagulants to help them better use.   1. Structural differences: Although both heparin lithium and heparin sodium can anticoagulate blood, there are differences in chemical structure and effective binding ions, resulting in differences in dissociation degree. Our company's heparin lithium is replaced from heparin sodium.   2. Anticoagulant activity: There is no significant difference in anticoagulant activity between heparin lithium and heparin sodium. Both can effectively inhibit the activity of thrombin, block the coagulation process, and thus have an anticoagulant effect. In clinical use and biochemical experiments, the two can usually replace each other.   3. Application field: Heparin lithium and heparin sodium are widely used in different fields. In addition to being able to perform in vitro anticoagulation, heparin lithium is also commonly used in fields such as cardiac surgery, hemodialysis, intravenous infusion, and venous catheterization. Heparin sodium, on the other hand, mainly appears in the form of anticoagulants for blood collection, protecting the cells and proteins in the blood collection sample from interference from coagulation and maintaining the original characteristics of the sample.   4. Storage stability and usage: Lithium heparin and sodium heparin have their own advantages in terms of storage stability. As long as stored in dry and dark conditions, they can maintain their anticoagulant activity for a long time. In addition, special attention should be paid to its dosage and usage method. Excessive use may lead to poor anticoagulation effect, and industry standard dosage should be followed. The dosage range of heparin lithium in the industry standard is 9.41-281U units/ml, while heparin sodium is 121U-301U per milliliter of blood.   Heparin lithium and heparin sodium are common heparin anticoagulants, although they are both anticoagulants, there are also differences. When using them, it is necessary to choose appropriate anticoagulants based on the specific situation, and pay attention to their storage stability and dosage to ensure safe and effective application in clinical and experimental settings. As a manufacturer of blood collection additives, Desheng can provide high-quality heparin sodium and heparin lithium, but both are analytical grade and added to test tubes for in vitro anticoagulation use. It cannot be used as a drug. This needs to be understood clearly. Welcome interested parties to contact us anytime to purchase!

Heparin sodium is a commonly used anticoagulant for blood collection, widely used in clinical blood collection and medical testing. Its mechanism of action mainly involves thrombin and antithrombin in the coagulation system, achieving anticoagulant effects through specific molecular structures and biological functions. The following will delve into the mechanism of action of heparin sodium to better understand its application in blood collection.   The Chemical Structure and Biological Activity of Heparin Sodium   Heparin sodium is a natural polysaccharide compound with complex and diverse chemical structures. It is mainly composed of glucosamine and glucuronic acid units, which form a specific polysaccharide chain structure through sulfation reaction. This special structure endows heparin sodium with anticoagulant biological activity.   Anticoagulant mechanism   The anticoagulant mechanism of heparin sodium is mainly achieved through the following aspects:   1. Inhibition of thrombin: Heparin sodium can form a stable complex with thrombin, thereby inhibiting the activity of thrombin and hindering its role in the coagulation process, thereby inhibiting the process of blood coagulation.   2. Promoting anticoagulant enzyme activity: Heparin sodium can also enhance the activity of antithrombin (such as antithrombin III), further inhibiting the activation of the coagulation system, and maintaining the blood in an anticoagulant state.   3. Inhibition of coagulation factor binding: It can inhibit the binding of coagulation factors in the liver, thereby reducing the tendency for blood clotting.   4. Inhibition of platelet aggregation: By inhibiting platelet aggregation and adhesion, the deposition of platelets on the inner wall of blood vessels is reduced, further slowing down the process of blood coagulation.   Advantages of heparin sodium   1. Quick action: Heparin sodium has a rapid anticoagulant effect and can achieve anticoagulant goals in a short period of time.   2. Widely applicable to biochemical projects: Blood samples processed with heparin sodium are suitable for various biochemical tests, such as liver and kidney function testing, blood glucose testing, and other biochemical categories in various medical scenarios.   Heparin sodium, as an effective anticoagulant for blood collection, its mechanism of action mainly involves multiple aspects such as inhibiting thrombin, promoting antithrombin activity, inhibiting coagulation factor synthesis, and inhibiting platelet aggregation. However, an important point in the anticoagulation treatment process is the need for stable and reliable heparin sodium raw materials. It is recommended to choose high-quality manufacturers, such as Desheng. Desheng has always been focused on the production of blood vessel additive raw materials, with strict requirements for various indicators of heparin sodium and obvious anticoagulant effects. If you have any related needs, please contact us to purchase!