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Latest company new about What are the differences between EDTA K2 and EDTA K3 in Applications
2022/10/20

What are the differences between EDTA K2 and EDTA K3 in Applications

Today, in the field of in vitro diagnostics, there are many kinds of blood anticoagulants, among which EDTA K2 and EDTA K3 are more common. Their basic anticoagulation principle is to use EDTA to chelate calcium ions in the blood, thereby preventing blood coagulation. Are there any differences between the two?   1. Different appearance Both are white powders, but in comparison, the powder of EDTA K3 is finer, and the effect of dissolving in water is also better, but this effect cannot be observed by the naked eye, and the comparison in the experimental effect is still very obvious.   2. Different chemical structures The biggest difference between the two in chemical structure is that K3 has one more potassium ion than K2, which causes the pH of the two solutions to be different. The pH of EDTA K2 needs to be controlled in a weakly acidic environment of 2.7-6.2, and the pH of its aqueous solution is around 4.8, while the pH of EDTA K3 needs to be controlled in a weakly alkaline environment of 6.2-10.2, and the pH of its aqueous solution is around 7.5. Therefore, the pH value of EDTA-K3 will be higher, and the solubility of EDTA K3 is greater than that of EDTA K2 in terms of solubility.   3.The usage is different In terms of use, EDTA K2 is more widely used than EDTA K3. EDTA K2 can not only be used for anticoagulation in blood collection tubes, complex metals and metal separation, but also often used in detergents, liquid soaps and shampoos. and sprays, while EDTA K3 can only be used for blood anticoagulation unilaterally.   In addition, for blood anticoagulation, EDTA K2 is used more, because once the EDTA concentration becomes stronger, EDTA K3 is more likely to cause red blood cells to shrink than EDTA K2. When the blood sample is placed for a period of time, EDTA K3 is more likely to lead to increased cell size. At the same time, it should be noted that although both of them are used for blood anticoagulation, they are also different in the use of blood collection tubes. EDTA K3 presents a liquid state in the glass tube of blood collection tubes, while the plastic tube is the same as EDTA. K2 is the same spray-dried state.   Hubei New Desheng Material Technology Co., Ltd. started out specializing in blood collection tube reagents. It has been developing for 17 years. It has been adhering to the principle of customer first, ensuring product quality, and committing to good reputation. The company has a special quality inspection department. All products are carried out under strict supervision. Problems are solved as soon as possible, and products with substandard quality are not allowed to leave the factory. Today, Desheng has earned reputation in the market, and its quality is well recognized by customers. If you have any needs in this regard, you can click on the official website to consult the details!
Latest company new about What Kind of Blood Collection Tubes Can Use Serum Separation Gel
2022/10/19

What Kind of Blood Collection Tubes Can Use Serum Separation Gel

As an organic compound with a hydrophobic material, serum separation gel has good thixotropic properties. After on-machine centrifugation, serum and blood clots are quickly separated, and a jelly-like isolation layer is formed between serum and blood clots, thereby preventing their interaction. The storage time and original properties of blood samples are ensured by passing through the separation gel compartment within a certain period of time, thereby improving the accuracy of blood testing.   Serum Separation Gel Parameters: Original Ezhou City,Hubei Brand Desheng Transportation By air,by sea Appearance Gel Size 25kg/drum Stock In stock   So which blood collection tubes can use serum separation gel? Here are details for you. 1. Nucleic acid detection tube Collection, delivery and storage of venous blood samples for nucleic acid detection by adding EDTA and serum separation gel to nucleic acid detection tubes. For the DNA amplification detection of HIV, DNA, and HCV of HBV, serum separation gel has a good barrier to the interference of hemoglobin in red blood cells to nucleic acid detection experiments.   2. PRP tube The Chinese name is "high-concentration platelet plasma", which is mainly used to extract platelet-rich plasma through the precise specific gravity of the serum separation gel in the tube, and then inject the platelet-rich plasma into the required part of the human body to achieve the purpose of cosmetic repair, regeneration or treatment. Therefore, the PRP tube is not used to check whether there is a disease in the body, but to extract high-concentration platelets for reuse.   3. CPT tube CPT tube is also called vacuum mononuclear cell preparation tube. It is mainly added into the tube through serum separation gel of different specific gravity to separate lymphocytes and monocytes in blood. It is suitable for clinical medical testing and can be used to check HLA or residual Leukemia genetic testing, tuberculosis testing, HIV testing, etc.   4. PST tube The main purpose is to separate blood cells, serum and plasma, increase production, ensure the stability of plasma components, collect plasma samples, eliminate clotting time, and are mostly used in intensive care and emergency inspections.   Desheng Biochemical is a manufacturer specializing in the research, development and production of serum separation gels and ohter additives for blood collection tube. It has been developing for 17 years. Whether it is in the equipment environment, production team and product quality inspection, it has invested a lot of energy and time. The separation gel has also been improved by the first generation, the second generation and the third generation, until the fourth generation was developed and produced. Its performance and stability have made a qualitative leap. The PH value will not change, and the serum separation gel produced by Desheng has its own patented technology. Welcome to contact for any inquiry.
Latest company new about About Medical Beauty PRP separation gel
2022/10/14

About Medical Beauty PRP separation gel

    Many female friends will use PRP when doing medical beauty, especially when treating dark circles, acupuncture, and wrinkle removal, but most people don't know much about PRP.         The full name of PRP in Chinese is high-concentration platelet plasma. It is a platelet-rich plasma obtained by extracting a certain amount of venous blood into a PRP tube, centrifuging and separating in vitro. It contains a variety of abundant growth factors, so it is widely used in medical beauty projects.         The PRP tube used in this process is a test tube specially used for the preparation of PRP plasma. Generally, serum separation gel is added to the test tube. This kind of separation gel has strict requirements on hydrolysis and specific gravity, and can control the precise specific gravity. Extract high-concentration platelets and inject them into the parts we need.         There are two kinds of separation gel routinely produced by Desheng, one is polyacrylic acid separation gel; the other is resin separation gel, both of which have obtained national patents. At present, the separation gel produced by our company has three appearances, transparent, translucent and opaque, with more obvious advantages and superior hydrophobic properties. The transparent gel is a unique appearance of our company. In terms of viscosity, the separation glue is customized, and few domestic manufacturers can provide such customized services.       With 17 years of development, Desheng's separation gel has developed into the fourth generation, from the previous generation that is not radiation resistant to the current resin system that is resistant to radiation, which is already ahead of most domestic manufacturers. Desheng has a professional R&D team for separating gel technology, with competitive prices and guaranteed quality. Now the daily output can reach 2-4 tons. The production technology and equipment are advanced, the delivery is timely, and the spot supply is guaranteed. If you have relevant needs, you can visit the official website or make a phone call.
Latest company new about Takes A Minute To Understand Desheng‘s TAPS Buffer
2022/09/29

Takes A Minute To Understand Desheng‘s TAPS Buffer

In recent years, Good's buffer has been applied in more and more fields, and TAPS, as one of Good's buffer products, has gradually been paid attention to. TAPS is soluble in water to a zwitterionic buffer, with a pH buffer range of 7.7-9.1, and is often used in biochemistry and molecular biology.   Specific applications of TAPS TAPS can be used as a buffer component for DNA and RNA samples, and can protect oxyhemoglobin from reacting to methemoglobin in a freeze-dried environment. In addition, it can be used as a background electrolyte for micro-analysis of proteins in the field of capillary analysis, and can be used as an important pH stabilizer for biochemical diagnostic kits.   How to use TAPS The TAPS buffer produced by Desheng is in powder form,packed in barrels with a large large quantities.Then how to use it? First, according to your own needs, take out an appropriate amount of TAPS powder and dissolve it with deionized water. Be careful not to add too much water during the dissolution process, and ensure complete dissolution, and then continue to add water to make up the volume. Pay attention to the temperature when the volume is fixed. The temperature changes too much due to exothermic or endothermic dissolving, and the volume should be fixed when the temperature is close to room temperature. After configuration, seal the cap of the volumetric flask, which can be kept for future use. Mark the TAPS solution, as well as the concentration configuration, date and other information.   What are the advantages of Desheng's TAPS Desheng has been specializing in the development and production of in vitro diagnostic reagent raw materials for 17 years. As a veteran manufacturer, the TAPS buffer produced has a purity of 99% and stable performance. In addition, the company has specially set up a quality inspection department, and the various indicators of TAPS have reached the qualified standards, which can be used in experimental inspections with confidence and will not interfere with the inspection results.   At present, Desheng has a sufficient supply of biological buffers, no matter how big your needs are, the company can meet you, and can quickly prepare enough supply for you, package and send it out. In addition, the TAPS we produce is packed in powder, which is safer and more convenient to transport. Unlike the ready-to-use solution,which may lead to deformation or leakage, which will affect the experimental process. If you have any demands,click on the official website to consult the details.
Latest company new about Anticoagulant for blood collection tubes-Tripotassium EDTA 
2022/09/07

Anticoagulant for blood collection tubes-Tripotassium EDTA 

Tripotassium ethylenediaminetetraacetate (EDTA-K3), as an amino polycarboxylate, has a strong ability to complex metal ions, and is often used as a chelating agent in hard water softeners to remove boiler scale and heavy metal mercury. Antidote etc. Tripotassium EDTA produced by Desheng Biochemical is mainly used as an anticoagulant in vitro. It is added to the vacuum blood collection tube. Generally, the pretreatment of blood samples is carried out in the process of clinical blood collection and testing.   The configuration of the EDTA tripotassium anticoagulant is to dissolve the EDTA tripotassium powder with a certain amount of distilled water, configure it into a solution of the required concentration, and then inject it into the blood collection tube. Compared with dipotassium EDTA, tripotassium EDTA is in the form of liquid in the blood collection glass tube, and in the form of dry spray in the blood collection plastic tube. When the tripotassium EDTA in the blood collection tube touches the blood sample, it complexes calcium ions in the blood, blocks the coagulation effect of calcium ions, and stops blood coagulation. Tripotassium EDTA, like dipotassium EDTA, also does not destroy blood cell components, does not affect the white blood cell count, and has the least effect on the shape of red blood cells, and is often used in routine blood tests. When tripotassium EDTA is added to the vacuum blood collection tube, it is usually used in combination with sodium fluoride and separating gel, and its anticoagulant effect is better. And in the case of non-irreversible anticoagulation with tripotassium EDTA, the test should be completed within 24 hours after blood collection to ensure the accuracy of the test results.   In addition, compared with sodium citrate and lithium heparin anticoagulants, tripotassium EDTA has a stronger ability to inhibit platelet aggregation. However, if EDTA tripotassium anticoagulation is used for blood analysis, it is found that the platelet count is too low for unknown reasons, and it is not suitable for the examination of platelet kinetics.   Hubei New Desheng is specialized in vacuum blood collection tube additives, not only R&D and production of tripotassium EDTA, but also serum separation gel, sodium heparin, lithium heparin, dipotassium EDTA, coagulant, high-efficiency coagulation accelerator Powder, etc., are conducive to meet the different needs of customers. This kind of blood collection tube additives, the purity is as high as 99%, and the quality is strictly controlled.
Latest company new about (4-Hydroxyethylpiperazineethanesulfonic acid) HEPES - the first choice for a variety of cosmetics
2022/09/07

(4-Hydroxyethylpiperazineethanesulfonic acid) HEPES - the first choice for a variety of cosmetics

(4-Hydroxyethylpiperazineethanesulfonic acid) HEPES - the first choice for a variety of cosmetics (4-Hydroxyethylpiperazineethanesulfonic acid) HEPES is a type of biological buffer and is widely used in the market. It can control the system for a long time, and the pH value is stable, and it will not complex metal ions. It is often used in livestock feeding cryopreservation buffer solution, or used to make cell culture fluid. In addition, it can also be used in various cosmetics. It has good buffering capacity, mild and non-irritating, whitening and exfoliating. The role of HEPES in cosmetics 1. Whitening (4-Hydroxyethylpiperazine ethanesulfonic acid) HEPES contains weak acidity, which can destroy the desmosomes connected between keratinocytes on the skin barrier, promote the exfoliation of the stratum corneum, and make the skin smooth, delicate and smooth, whitening and translucent. effect. 2. Strong pH buffering ability ① The ingredients in many cosmetics are polypeptides, nucleic acid substances and fermented extracts. These substances often require a stable acid-base environment, and the pH value is in the range of 6.0-8.0, otherwise these functional ingredients are easily inactivated. While formulations are sometimes susceptible to oxidation during storage, resulting in a drop in pH, HEPES effectively stabilizes these ingredients within a reasonable pH range. ②The pH range of the microbial fermentation extract needs to be in the environment of 6.0-8.0 to maintain its activity, and the usual pH buffer system is not suitable. Phosphate radicals such as potassium dihydrogen phosphate/sodium buffer system will precipitate with metal cations in the extract and are not suitable for use. However, (4-hydroxyethylpiperazineethanesulfonic acid) HEPES has a pH buffer range of 6.8-8.2, and does not complex with metal cations such as magnesium ions and calcium ions, and has a pKa of 7.48 at ambient temperature of 25 °C. Ideal for microbial fermentation extracts to maintain activity. 3. Anti-inflammatory effect HEPES itself has a good anti-inflammatory effect, by reducing the amount of active oxidation products in peripheral blood mononuclear cells, it plays an anti-inflammatory effect and provides a new anti-inflammatory method. (4-Hydroxyethylpiperazineethanesulfonic acid) HEPES is widely used in cosmetics, such as polypeptide products, whitening and anti-aging products, exfoliating products, etc. As a supplier of HEPES, Desheng has officially passed the certification of cosmetic raw material submission code, which can meet different cosmetic customer groups. Feel free to contact us!
Latest company new about The PH Stabilization Buffer Of 3-Morpholinepropanesulfonic Acid
2022/07/01

The PH Stabilization Buffer Of 3-Morpholinepropanesulfonic Acid

3-Morpholinepropanesulfonic acid is abbreviated as MOPS, CAS No. is 1132-61-2.It is a zwitterionic buffer commonly used in biochemistry and molecular biology, and its structure is similar to 2-(N-morpholine)ethanesulfonic acid (MES), also one of the "Good" buffers classified by Dr. Norman Good and colleagues in 1966. It has a wide range of applications, such as for mammalian cell culture (recommended concentration should be ≤20 mM), RNA denaturing agarose gel electrophoresis experiments (20 mM concentration is better for formaldehyde gels), discontinuous Polyacrylamide gel electrophoresis experiments, etc.   PH stability of 3-morpholinopropanesulfonic acid (MOPS) The PH stability of 3-morpholinepropanesulfonic acid and its effect on vascular tension in vitro were studied experimentally. The results showed that the PH changes of MOPS buffer and K+-MOPS solution within 14 days were basically constant at (7.32±0.04)~(7.51±0.04) 0.04). The aeration rate had little effect on the pH of MOPS solution, and the range of change was (7.24±0.04)~(7.39±0.00).While the Krebs solution was sensitive to the aeration speed, and the pH range was (6.81±0.81±0.00) between 15 and 60 bubbles/min. 0.07)~(8.33±0.02), the fluctuation range is large.   Changes in the volume of MOPS solution and Krebs solution under the same ventilation rate have little effect on their pH. The isolated rat mesenteric artery, cerebral basilar artery and coronary artery can produce good contraction in MOPS solution. Therefore the MOPS solution has the advantages of stable pH, long standing time, easy ventilation, and low application cost, and can be used in mammals experiments on isolated tissues and organs such as blood vessels.   Precautions for the use of 3-morpholinopropanesulfonic acid (MOPS) 1. MOPS can interfere with Folin protein analysis, and autoclaving of MOPS solution containing glucose will cause its partial inactivation. 2. MOPS powder can be stored at room temperature for several years. However, upon standing, the bulk powder may clump together and form hard lumps without affecting its chemical properties. 3. Storage method: MOPS powder can be stored stably at room temperature for several years. Prolonged storage may clump without affecting its use and chemical properties. 4. MOPS buffer can be stored at 2~8°C for at least 6 months, and sterilized by filtration with a 0.2 μm filter. Autoclaving is not recommended. To prepare a nuclease-free MOPS solution, autoclave the water before adding the powder to dissolve.   In the current market, Desheng is one of the most professional MOPS manufacturers in China, with a professional team for R&D and production. Desheng currently develops dozens of biological buffers, which have been traded in many regions around the world and are well received by the industry. If you are interested in MOPS or other buffer products, you can contact customer service for details.
Latest company new about How To Evaluate The Performance Of Blood Coagulants
2022/06/30

How To Evaluate The Performance Of Blood Coagulants

Serum is one of the main samples for clinical biochemical, immune and other tests. At present, the method of obtaining serum samples in medical institutions is mainly by collecting venous blood and centrifuging it after the blood is completely coagulated. Under normal circumstances, it takes more than 60 minutes for blood samples to be completely coagulated after isolation, which is difficult to meet the needs of rapid laboratory testing. The containers used for collecting venous blood samples in medical institutions mainly include blood collection tubes with coagulant or blood samples collected with disposable syringes and then injected into non-vacuum containers. The materials of the containers are glass or plastic. The coagulation process needs to include at least three basic biochemical reactions: ① Formation of prothrombin activator; ②Prothrombin activator converts prothrombin into active thrombin with the participation of calcium ions; ③ Soluble fibrinogen is converted into insoluble fibrin under the action of thrombin. Macroscopic clot formation is both a physical phenomenon of fibrin formation and the final point of a series of enzymatic biochemical reactions. There are many clotting factors involved in the whole process. Under physiological conditions, coagulation factors are generally in an inactive state. When these coagulation factors are activated, a series of enzymatic reactions that are still recognized as the "waterfall theory of coagulation mechanism" will occur and lead to blood coagulation. Tissue factor, namely tissue thromboplastin or coagulation factor III, is the only coagulation factor that does not exist in animal blood. It is a lipoprotein, and its main component is phospholipid. Tissue factor lipoprotein is widely present in animal tissues such as brain, lung and placenta. It is released after tissue damage, acts on the extrinsic coagulation system, and promotes coagulation with the endogenous coagulation system products under the catalysis of thrombin. Coagulation pathway to achieve coagulation effect. The main function of blood coagulants is to accelerate blood coagulation, that is, to shorten the blood coagulation time in vitro without affecting the necessary components of blood, and to promote serum separation. The performance evaluation of blood coagulants should be considered from the following aspects: 1) Coagulation time: the time required for blood to fully coagulate after contacting with the coagulant. 2) Procoagulation efficiency: the relative amount of coagulant added to make the blood achieve the best coagulation effect. 3) Coagulation effect: the amount of serum exudation after blood coagulation. 4) Separation effect: whether the blood after coagulation can achieve complete and clear separation of serum after centrifugation, and whether hemolysis occurs. 5) Effects on essential components of blood: The use of coagulants cannot have a harmful effect on the clinical test results of blood and the performance and quality of blood products.   Hubei New Desheng is a professional manufacturer of coagulant with good performance.We made blood collection tube additives for more than 17 years. Welcome inquiry if you need it.
Latest company new about Simple Introduction Of EDTA K2,EDTA K3 and EDTA Na2
2022/06/29

Simple Introduction Of EDTA K2,EDTA K3 and EDTA Na2

What are the differences among EDTA K2,EDTA K3 and EDTA Na2? I believe many people don't know, so let's talk about the differences in the uses of these three products today!   Ethylenediaminetetraacetic acid dipotassium (EDTA K2) ethylenediaminetetraacetic acid is an amino polyacid.It is a general-purpose strong complexing agent for forming complexes with most metal ions.EDTA K2 is an anticoagulant commonly used in blood analyzers. It has the characteristics of good anticoagulation effect and less influence on the morphology of blood cells. Blood analysis is a routine test item in clinical medicine. The vast majority of patients undergo this test. From the beginning of manual detection to fully automatic detection.   EDTA K3 is an amino polyacid.Although the integration of EDTA has long been used for extraction, cation exchange, separation of rare elements, volumetric analysis of calcium, magnesium, and barium, softening of hard water, and use as masking agent, metal cleaning agent, antidote for heavy metal poisoning, bactericide, etc. However, in-depth research on its structure and integration mechanism was done after 1958.   Some studies have shown that unexplained low platelet counts are found in blood analysis with EDTA-K3 anticoagulation, and the patient should be manually checked for blood slices and PLT manual counts, or diluted with unanticoagulated peripheral blood. Check the PLT count directly with the instrument for blood cell analysis to correctly understand the true level of the patient's PLT. Especially cancer patients, autoimmune diseases, pulmonary heart disease, pregnant women, advanced liver disease and other patients.   EDTA Na2 is often used in coordination burettes to measure the composition of metal ions. EDTA Na2 has main uses in industrial production such as dyes, food, and pharmaceuticals. EDTA Na2 is milky white crystalline particles or powder, odorless and odorless. It can dissolved in water, not easily in alcohol. It is a key antioxidant that chelates metal ions in aqueous solutions. And can avoid discoloration, mildew, turbidity and air oxidation damage of vitamin C caused by metal materials, and also improve the antioxidant of vegetable oils,a small amount of metal materials such as iron and copper in vegetable oils can promote the air oxidation of vegetable oils.   According to the application quality standards of food preservatives in my country, EDTA Na2 can be used in canned aquatic products, canned fruits with red bean syrup and chestnut, etc. The maximum demand is 0.25mg/kg. It can maintain the color, aroma and taste of canned fruit food. For canned aquatic products such as crab and shrimp, the addition of EDTA Na2 can avoid the dissolution of Struvite, a laminated glass-like crystal, to ensure the quality of processed products. . It is also used as stabilizer and adhesive for sauce products and canned fruits, and the maximum demand is 0.25g/kg.   I believe the above make it clear for the use of EDTA K2,EDTA K3 and EDTA Na2. But all ours are produced for blood collection tube additives, pls feel free to contact if you need them.
Latest company new about VTM In Nucleic Acid Detection And Antibody Detection
2022/06/28

VTM In Nucleic Acid Detection And Antibody Detection

There are generally two ways to detect the virus of Covid-19, nucleic acid detection and antibody detection. But we generally make nucleic acid testing, and naturally ignore antibody testing. This is because antibody detection is generally used as a supplementary detection indicator for suspected cases with negative nucleic acid detection for the Covid-19 or in conjunction with nucleic acid detection in the diagnosis of suspected cases. It cannot be used as a basis for diagnosis and exclusion, and is more suitable for retrospective examination. So what is the difference between the two tests? Which test is the VTM more suitable for?   VTM (Virus Transportation Media) It is a liquid used for virus sample testing. There are mainly two types of inactivated and non-inactivated. The inactivated type can quickly inactivate the virus and release the virus’ nucleic acid for rapid nucleic acid detection.The non-inactivated type can protect the activity of virus’ RNA and protein at the same time, which can be used for virus nucleic acid detection and antibody detection.   The differences between nucleic acid detection and antibody detection 1.Different samples Nucleic acid detection requires respiratory samples, including pharynx, nasopharyngeal secretions, sputum, bronchi, lavage fluid, lung biopsy, etc. The collection process is very complicated. Antibody detection is a blood test, which can be collected by peripheral blood or venous blood collection. The sample collection method is more convenient and safe, and the sample can be stored for 72 hours. 2.Different detection methods Nucleic acid testing is a direct detection of viruses. It takes the specific DNA sequence of the virus as the detection target.Through PCR amplification, the target DNA sequence we chosen increases exponentially. Each amplified DNA sequence can be combined with a pre-added fluorescent marker. The probes bind, producing a fluorescent signal. The more target DNA amplified, the stronger the accumulated fluorescent signal. In samples without virus, no increase in fluorescence signal was detected because there was no amplification of the target DNA. Moreover, the nucleic acid sample has harsh storage conditions, RNA is easily lysed, and can only be stored for 24 hours at 4°C. Antibody testing is an indirect test. It is not directed against the virus itself, but a specific antibody produced by the immune response of the human body after infection with the virus . The human body gradually produces antibodies about a week after being infected with the virus and then rises rapidly. The human body generally produces antibodies called IgM first. A positive IgM antibody indicates a recent infection, and a positive IgG antibody indicates a long period of infection or previous infection. 3.Different detection conditions Nucleic acid testing requires specialized instruments and standard molecular testing laboratories. PCR certification personnel required to operate. The steps are cumbersome and the whole process takes 5 to 8 hours. The risk of contamination during the process is high. Antibody detection breaks through the limitations of existing nucleic acid detection methods on personnel and places. It can be detected in large quantities quickly, and can be completed in primary laboratories with low risk of contamination.   It can be seen from above there are advantages and disadvantages for no matter what kind of Covid-19 virus detection method is used. Antibody detection is a supplement to the false negative of nucleic acid detection. The combination of the two can effectively improve the diagnostic efficiency of the Covid-19, and has extraordinary value for epidemic prevention and control.   We are factory of VTM and IVD reagent, welcome to inquiry if you need it.
Latest company new about Dipotassium EDTA CBA In Blood Collection Tube Additives
2022/06/28

Dipotassium EDTA CBA In Blood Collection Tube Additives

Dipotassium EDTA is an anticoagulant commonly used in blood analyzers. It has the characteristics of good anticoagulation effect and less influence on the morphology of blood cells. Blood analysis is a routine test item in clinical medicine. The vast majority of patients undergo this test. From the beginning of manual detection to fully automatic detection. All demands are increasing.   Ethylenediaminetetraacetic acid dipotassium (EDTA-2K) ethylenediaminetetraacetic acid (abbreviated as Dipotassium EDTA) is an amino polyacid.It is a general-purpose strong complexing agent for forming complexes with most metal ions. The past research on Dipotassium EDTA complexes and chelation has focused on three aspects. 1. What attracts more research forces is the most stable metal complex of Dipotassium EDTA,the chelate of transition elements and rare elements. 2. A batch of complexes with moderate complexing strength, such as the accumulation of alkaline metals. Since it is difficult for general reagents to achieve the complexation of alkali metals, the complex of Dipotassium EDTA alkaline metals has attracted people's attention in particular; 3.Through the sequence of Dipotassium EDTA itself and co-alkali metal salts, the research on the affinity of Dipotassium EDTA acid radical to proton is focused.   Dipotassium EDTA is an amino polycarboxylic acid and calcium chelator.It has a great affinity for calcium ion in blood, which can effectively chelate calcium ion or remove calcium reaction sites in blood samples.The drop of calcium ion will block and stop the endogenous or extrinsic coagulation process, thereby preventing the coagulation of blood samples.Each 0.8mg can anticoagulate 1ml of blood. Except that it cannot be used for the determination of calcium and sodium containing substances in plasma, it is suitable for various anticoagulation. Dipotassium EDTA can also complex some ions in plasma to make certain of proteins or nucleic acid substances more stable.But the interference of the formation of chromium compounds on samples and experiments should be considered.   Dipotassium EDTA is suitable for general hematological tests, but not for platelet count. Because it affects platelet aggregation and blood cell phagocytosis. It is not suitable for coagulation imaging and platelet function tests, nor for calcium, potassium, NaFe, alkaline phosphatase, creatine Kinase and leucine aminopeptidase assays and PCR assays.   Dipotassium ethylenediaminetetraacetate (EDTA-K) is additives of vacuum blood collection tubes,anticoagulation of 2ml blood requires 4mg of Desheng ethylenediaminetetraacetic acid dipotassium (EDTA-K). Because the concentration is low, in order not to dilute the blood, 20ul of an aqueous solution containing 200g/L of dipotassium ethylenediaminetetraacetate (EDTA-K) is generally used in each blood collection tube. When the water is evaporated on the tube wall,the Dipotassium EDTA in the tube to crystallize quickly. The blood collection tubes must be turned upside down for at least 8 times, so that the crystallized dipotassium ethylenediaminetetraacetate (EDTA-K) can be fully dissolved and mixed in the blood.   Desheng is a professional manufacturer of Dipotassium EDTA. Our blood collection tube additives have been recognized by many tubes manufacturers. If you have any requirements, please contact us!
Latest company new about Desheng,A Well-reputed Materials Manufacturer Of IVD Reagent
2022/06/27

Desheng,A Well-reputed Materials Manufacturer Of IVD Reagent

Hubei New Desheng Material Technology Co., Ltd. was established in 2017.It is a production enterprise specializing in R&D, production and sales of material for IVD reagent. At present, the company's products include  blood collection tube additives, biological buffers, chromogenic substrates, chemiluminescence reagents and enzyme preparations. In terms of blood collection tube additives, it has formed independent intellectual property rights and professional production and R&D capabilities.   At present, our company mainly has a series of blood collection tube additives, including sodium heparin, lithium heparin, trisodium citrate, dipotassium EDTA, tripotassium EDTA, potassium oxalate, blood coagulation powder, blood coagulant, serum separating gel, silicifying agent,etc. The raw materials of diagnostic reagents include biological buffers and chromogen substrates. At present, chromogen substrates,also known as new Trinder's reagents, include TOOS, TOPS, ADOS, ADPS, ALPS, DAOS, HDAOS, MADB, MAOS, TODB, etc.They are white,which are different from light blue or brown products on the market.White crystal biological Buffers include TRIS, HEPES,BICINE,CAPS, MOPS, TAPS, EPPS, etc. Which max absorbance is 0.05.Self-developed chemiluminescence substrates include luminol, isoluminol, acridine ester and enzyme substrate PNPG,all with high purity.   The company focuses on the blood test reagent industry, and is determined to become the world's leading brand and contribute to the human health. Since its establishment, the company has always adhered to the core business philosophy of "morality-based, honesty-first", and regards providing value to customers as our responsibility, which has been well received by customers.   The product quality and technology of New Desheng have been widely recognized and used by customers in the Chinese domestic market. Over the years, many well-known blood collection tube manufacturers in China have been choosing our products.Desheng Technology will continue to devote to develop the advanced material for IVD reagents to meet the needs of the development of global medical testing technology and strive for the human health.Welcome your inquiry on related products.
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