China Wuhan Desheng Biochemical Technology Co., Ltd Company News

Today we will introduce TRIS, HEPES, TAPS, the team products in the Good’s buffer produced by Desheng.   TRIS (Trishydroxymethylaminomethane): Weakly alkaline, with a pKa of 8.1 at 25°C, and the effective buffer range of its buffer is between pH 7.0 and 9.2. It is often used as a buffer in electrophoresis and gel experiments, and is widely used as a solvent for nucleic acids and proteins. It can also be used for the formation of nematode intermediate fibers. The most common role in cosmetics is to adjust the PH value (pH). It can also be used as a neutralizer to neutralize a thickener (carbomer) to reduce stickiness, improve skin cell respiration efficiency, and prevent pore clogging . In addition, TRIS can be used as an odor regulator in cosmetics containing amine salts to adjust the amine odor generated by friction when applying cosmetics, so as to avoid any residual or sustained odor release. HEPES (4-hydroxyethylpiperazine ethanesulfonic acid): It is a zwitterionic biological buffer, belonging to Good’s buffer, with an effective buffer range of 6.8~8.2. It can be widely used in a variety of biochemical reactions and used as a buffer reagent in certain cell culture media. In addition, due to its non-cytotoxicity, HEPES buffer is often used in the research of organelles and highly variable, pH-sensitive proteins and enzymes, as well as biochemical diagnostic kits, DNA/RNA extraction kits and PCR diagnostic kits. TAPS (Trimethylol methylamino propane sulfonic acid): It is also a zwitterionic buffer. In biochemical experiment projects, it can be used as an important pH stabilizing reagent. It is generally mixed with weak acid and its conjugate base to obtain an appropriate pH value. TAPS reacts with most organisms under neutral conditions. The pH value is required to be selected in the range of 6 to 8. At the same time, the effective buffer range of the buffer should also be specified in the range of 6-8. Moreover, it is necessary to ensure that the pH form of the buffer reagent cannot chelate with certain metal chemical ions. In the field of clinical diagnosis, TAPS is also commonly used as a biological buffer. Usually used in some biochemical diagnostic kits, PCR diagnostic kits and DNA/RNA extraction kits and other kits.

In our nucleic acid examination, we will use our company's product: Virus Transport Media. In fact, the Virus Transport Media is also divided into multiple models, and there is also a twin brother: cell preservation solution.   Among them, the Virus Transport Media is roughly divided into two types: inactivated type and non-inactivated type. It can be understood from the literal meaning that there are differences in the preservation principles of the two types of Virus Transport Medias. Here is a brief introduction. The first non-inactivated type can protect the protein and nucleic acid of the virus, and the other is the inactivated type, which usually contains the lysis salt of the inactivated virus, which cleavages the protein to protect the nucleic acid. Among them, if the non-inactivated Virus Transport Media cannot be tested in time after sampling, it must be stored below 4 degrees Celsius and the preservation time should not exceed 48 hours. If it cannot be delivered to the test site within time, it needs to be Store in ultra-low temperature below minus 70 degrees Celsius. Otherwise, it will affect the virus test results, so you need to select the type of Virus Transport Media corresponding to the situation when selecting the Virus Transport Media. Many people confuse the Virus Transport Media with the cell preservation solution. In fact, the cell preservation solution is a general-purpose cell cryopreservation solution that can be used to preserve animal and human cell lines. Cell preservation is a cytology experiment. Important technical means. In cell line establishment and line establishment, it is very important to freeze the original cells in time.   At present, cell preservation mostly uses glycerol or dimethyl sulfoxide protective agent, which can improve the permeability of the cell membrane to water, and then slow freezing can make the water in the cell seep out of the cell, reduce the formation of ice crystals in the cell, thereby reducing Cell damage caused by ice crystals. The cell preservation solution has a diluting effect, which can isolate a large number of effective cells embedded in the mucus, allowing more valuable cells to be preserved, providing a sufficient number of cells, and providing a guarantee for the accuracy of the test results.   Therefore, although the purpose of the Virus Transport Media and the cell preservation solution are similar, there are some differences in principle. Virus Transport Media is preserved by protecting nucleic acid, while cell preservation solution is preserved by improving cell capacity and protection. These two preservation solutions should be able to distinguish between them after the above understanding.

Carbomer 940 is a kind of polyacrylic acid cross-linked polymer, mainly used for thickening of daily chemical products. It can achieve the effect at very low concentration. Carbomer 940 is usually used to increase the viscosity of cosmetics such as shampoo, shower gel, detergent, and some creams. Most daily chemical products contain this ingredient, so as a chemical product with such a wide range of applications, The price of Carbomer 940 is a general concern of buyers. As a necessary raw material for hand-washing gel, Carbomer 940 has been in short supply during the epidemic this year, and the price has fluctuated greatly. After the epidemic has gradually subsided, as more Carbomer 940 manufacturers are put into production In China, the price of Carbomer 940 is slowly returning to a stable level. As a domestic high-quality carbomer manufacturer, the price is very competitive, and the quality of Carbomer 940 is on par with imported products. Recently, the sales department of Desheng reported that many customers went offline after consulting the price of Carbomer 940 because they did not get a clear reply. They went offline without a trace. Here we must be fair to the customer service. Is the online customer service available? Knowing the specific order quantity, it is impossible to give a clear response. The 940 kg price of Carbomer is definitely different from the ton price. This is the same as retail or wholesale. Large quantities are more favorable. The same applies to the chemical industry, so it is very important to remember to clearly express the order requirements when consulting the price of Carbomer 940. In addition, if you want to find Carbomer 940 with high quality and low price, it is a wiser choice to find a factory direct seller. In order to seize the current carbomer market enthusiasm, many merchants purchase Carbomer raw materials at low prices and provide them to buyers. It has caused many unqualified phenomena after use, because the product is not developed and produced by itself. Once there is a quality problem, there is no after-sales guarantee. Desheng develops and produces carbomer by itself, which gives buyers a "boosting shot". It not only provides product quality assurance, but also solves customers' troubles. In addition, the price of Carbomer 940 is much lower than other merchants, so it is a very wise choice to choose Desheng. Desheng has always insisted on providing customers with high-quality, cost-effective products. If the quantity of Carbomer 940 you need is relatively large, you can enjoy price concessions. The current ton-level price is 130 yuan/kg. In addition, Desun can also provide free samples of Carbomer 940. You can follow other products on the market. For comparison, Desheng always believes that good products can withstand the test of the market. If you have a need, you can click on the official website to consult customer service.

In biological experiments, there is a very important pH stabilizing reagent, that is, the biological buffer CAPS. Usually in the experiment, an appropriate weak acid and its conjugate base will be selected and mixed to obtain a suitable pH value. It has been proved in a large number of experiments that most biological reactions occur under neutral conditions. Generally, the pH value is between 6-8, and the effective buffer range of the buffer is required to be between 6-8. Therefore, it is required that the acid-base form of the buffer does not chelate with certain metal ions.   CAPS, also known as 3-cyclohexylaminopropanesulfonic acid, is a biological buffer, which can be used as a buffer for enzymatic chemistry and HPLC separation of alkaline drugs. Appearance is white crystal or powder, CAPS can be dissolved in water, PH buffer range is 8.9-10.3, PKA value is 9.6 when below 25℃, molecular weight is 243.28, CAS number is 1135-40-6. CAPS has a wide range of applications, including biochemical diagnostic kits, DNA/RNA extraction kits and PCR diagnostic kits, as well as buffers for enzymatic chemistry and HPLC separation of alkaline drugs. Moreover, CAPS is also a raw material for manufacturing welding materials and air-conditioning equipment, as well as for manufacturing metal lithium. And CAPS also has many applications in industry, such as new coatings and new materials. When CAPS is used as a biological buffer, high purity is required, usually analytically pure. When used in industry, the purity requirements are relatively low, but different treatments are required for different applications. And CAPS has a very wide range of applications, so there are many relative manufacturers, and these issues need to be paid attention to when choosing a manufacturer. Desheng Bio has been engaged in the research and development and production of biological buffering agent projects for many years and has very rich experience. CAPS is one of the core products, and it is well received in the field of biochemical diagnostic reagents and the market of new coating products. Desheng has established a company for decades. The company's products are sold globally. At present, it has been sold to more than 100 countries around the world. The products are of good quality and more favorable prices. If you are interested, you can call for consultation. Desheng Bio welcomes your calls.

Virus Transport Media is the transportation and preservation medium of virus, chlamydia, mycoplasma and Ureaplasma samples. Avoid aerosol infection. It plays an important role in the research center of viral pathology. It is commonly used for the collection and transportation of clinical influenza, avian influenza, hand, foot and mouth disease, measles and other virus samples, as well as Mycoplasma, Ureaplasma, chlamydia and other samples. The basic matters of use are described below. handle: Before sampling, write the sample information on the sticker. According to the experimental purpose, samples were collected from the corresponding parts with cotton swabs. Immediately after sampling, put the swab back into the anti-corrosion solution, break the swab rod and tighten the cover. In the inactivated transport and preservation medium of collected specimens, the tubes can be transported to the laboratory at room temperature (5-25 ℃) within 7 days. Avoid repeated freeze-thaw cycles. For best performance, complete the test within 24 hours in a controlled temperature environment.   Specific sampling method: a) nasal swab: gently insert the swab head into the nose of the nasal canal, stand for a while, and then rotate slowly. Wipe the other side of the nostril with another swab, immerse the swab head in the preservation solution, break the swab rod and discard the upper rod（ Applicable to the sampling of this product) b) pharyngeal swab: wipe bilateral pharyngeal tonsils and posterior pharyngeal wall with the swab, immerse the swab head in the preservation solution, break the swab rod and discard the upper rod（ Applicable to samples of this product).   matters needing attention: Please read this instruction carefully before use. Do not use after the expiration date. Do not use if the original seal of the media and cotton swab is damaged. Before using the product, please check the outer package of the product to ensure that it is complete and free of content overflow. The label shall be clear and the content shall be clear without falling off. The stored solution shall be pre loaded into the sampling tube. Low temperature precipitation is a normal phenomenon. The transport and storage medium for biological inactivation is a transparent solution. Do not use it if the color of the medium becomes turbid or turbid; The transportation and storage medium for biological comma inactivation is orange red solution. If the color of the medium changes from light orange to red, do not use it.   Avoid contact with eyes and skin. Do not contaminate the tip of the swab before sampling. Be careful when inserting a cotton swab into the mouth for oral sampling. Avoid the risk of suffocation. For single use only. Different patients are prohibited from using the same swab or test tube. Searching for specimens of viruses, chlamydia and Ureaplasma involves the risk of infection, which must be collected with appropriate PPE and treated for biological risk in accordance with published guidelines and local regulations.   Storage: For optimum performance, the product must be stored in its original packaging at a temperature of 5-25 ° C until use. Do not expose to overheating or direct sunlight before use.   Desheng biochemical is committed to the research and production of additives in blood testing, including blood collection preparation, edat sodium salt, potassium salt, heparin, coagulant, separation gel, Virus Transport Media, Carbomer 940 / 980 hand sanitizer, etc.

Carbomer is a white, loose powder with strong hygroscopicity and soluble in water, ethanol and glycerol. It can be used as external emulsion, cream and gel. In the neutral environment, carbomer gel system is an excellent gel matrix. It is crystal clear and feels lubricated. It is very suitable for preparing cream or gel. At the same time, because of its simple process, good stability and comfortable feeling, it is widely used in topical administration, especially in skin and eye gel. Although it can be combined with water to form gelatinous transparent emulsion alternation, it is not directly dissolved in water like traditional inorganic salts. Today, we introduce an alkaline preparation method to prepare the ideal carbomer gel solution.   First weigh 1g carbomer 940 dry powder and put it into a 50ml dry beaker. If there is caking, please grind it with a spoon. Then add 25ml purified water and stir while adding to make carbomer 940 fully absorb water and dissolve. This step is very important. Carbomer 940 must fully absorb water. Generally, Carbomer 940 can fully dissolve and swell only after adding water and stirring for a few hours. If you want to be faster, you can heat it in a water bath. It will be faster to stir while heating. Of course, even if heating can accelerate the water absorption and swelling process of carbomer 940, it will take 10 ~ 30 minutes. Then use the drop tube to add alkaline solution, stir it side by side, and measure the pH value at the side. When the PH7 is adjusted, the gel is successful. Triethanolamine can be used as alkali solution). At the same time, make up the remaining water. The total volume is about 50ml. The prepared gel base agent can directly mix various kinds of gels with other raw materials. As long as the concentration of carbomer is controlled within 0.8%, it is recommended to be suitable for about 0.5%. Only 0.5% of the concentration can produce gel products with good appearance and texture. For example, the gel made of 100ml is only required to take the polymer gel 25g with a pre modulation of 2% concentration into the formula of 75ml. 2% transparent gel 100ml = 2gm gel powder + 98ml pure water + 0.5ml antibacterial agent + moderate neutralizer. DIY carbomer 940 gel.   Special reminder: don't add things indiscriminately! Such as soluble salt, VC, highly acidic solution (lemonade, vinegar). In addition, the carbomer 940 gel system becomes thinner immediately. Hyaluronic acid is also acidic, but because of its small amount of addition, it has little effect on the stability of carbomer 940 gel system, and it can be safely added. Similarly, pure dew is slightly acidic and has little effect after addition.   Carbomer 940 itself is not nutritious, does not support the growth of bacteria and mold, but it can not prevent bacteria and mold from growing in the presence of nutrients in the gel system. So don't add too much at a time. Of course, you can add a little preservative or essential oil as needed.) Ultraviolet radiation has a certain effect on carbomer 940 gel system, so avoid light preservation. When preparing skin care products, the final concentration of carbomer 940 is controlled within 0.8%, which is recommended to be about 0.5%. If the concentration is greater than 0.8%, it is easy to form a film and the skin feels bad. Personal suggestion is about 0.7 beautiful, too thin is close to the thicker essence of liquid.   Desheng biochemical was founded in 2005, specializing in the R & D, production and sales of carbomer 940 / 980. Based on years of practice, it has formed a production and R & D capacity with independent intellectual property rights and professional. Provide products and raw material solutions for domestic and foreign daily washing and cosmetics manufacturers.

Carbomer is a highly hydrophilic anionic polymer. It is a white loose powder with strong moisture absorption. It can swell rapidly in water, but it does not dissolve. The aqueous dispersion solution is acidic, the pH value of 1% aqueous dispersion is about 2.5 ~ 3.5, and the viscosity is low. When neutralized by alkali, the viscosity gradually increases with the gradual dissolution of macromolecules, forming a clear solution at low concentration, forming a semitransparent gel at a relatively large concentration. PH 6.5 ~ 7 has the greatest viscosity and consistency. When the dispersing solution of polymer glue is neutralized with alkali, a transparent and stable gel is formed.   How to quickly dissolve the white carbomer powder into water to make a transparent solution? From the German Sheng biological staff, here to explain to you directly do Kapo gel method, I hope to help you.   Prepare the following three raw materials: a carbomer 940 1g pure water 99ml, B triethanolamine drops, C antibacterial agent 0.5ml. Tools: mixing rod, measuring spoon / measuring cup, pH measuring paper and an empty jar. Place the A in the empty jar and stir quickly until it is even. If there is a lump, it can be crushed with a stirring stick. Or only half of the water is added. The remaining part is added before the transparent gel is formed. Stand aside and stir until carbomer 940 fully absorbs water and expands without caking. It takes about 2 ~ 3 hours for the colloid to fully expand and form. If you want to shorten the colloid formation time, you can use the water separation heating method to stir while heating, which takes about 10 ~ 30 minutes   Add the alkali to neutralize. Add a drop and a drop in the drop. Measure the pH value with the side stirring. At pH7, it is transparent gel. This step is very important. It is the key to the formation of transparent gel. When making the first time, it is best to add a drop of neutralizer - agitation - measure the pH value, repeat this step to pH value until 7, so that the technology of modulation can be easily grasped. Next, it is easy to make. Add antibacterial agent, stir evenly, gel finish. It should be noted that in general, about 1.35g of triethanolamine is required to neutralize 1g of polymer glue. Avoid compatibility with raw materials such as salts or acids, which will reduce its viscosity. It is stable in pH 4-10.   Triethanolamine is an alkalizing agent used to adjust the pH value of the product. Avoid using with nitrosylating agent. The maximum use concentration is 2.5%. Avoid using it in the same formula with formaldehyde as preservative. May cause skin irritation and sensitivity.   Desheng biochemical was founded in 2005, specializing in the R & D, production and sales of carbomer 940 / 980. Based on years of practice, it has formed a production and R & D capacity with independent intellectual property rights and professional. It provides products and raw material solutions for more than 100 manufacturing enterprises at home and abroad.

Chemiluminescence detection is a technique that allows detection with ultra-high sensitivity. The representative reagent is luminol acridinium ester. Chemiluminescence is a kind of luminescence phenomenon. After the substance absorbs external energy from electromagnetic waves, heat, friction, electric field or chemical reaction, it emits light of a specific wavelength without generating heat, and returns to the ground state from the excited state. When the source of absorbed energy is a chemical reaction, this phenomenon is called chemiluminescence. When light is absorbed by energy, this phenomenon is called photoluminescence, and this phenomenon includes fluorescence and phosphorescence. The light emitted by fireflies and deep-sea creatures is called bioluminescence.   Figure 1 Chemiluminescence reaction caused by luminol Talk about the characteristics of chemiluminescence detection. Chemiluminescence does not require a light source lamp (such as a xenon lamp) because the material is excited by the energy of the chemical reaction caused by the luminescent reagent. Like post-column derivatization, the luminescent reagent used for the chemical reaction is continuously added to the column eluent by the luminescent reagent delivery pump, and mixed with the column eluent in the mixer. When the luminescence reaches the highest intensity, the photomultiplier tube measures the luminescence caused by the chemical reaction. Coil tubes made of ductile fluoroplastics are often used as chemiluminescence flow cells because it allows the photomultiplier tube to receive as much emitted light as possible. Examples of chemiluminescent reagents are as follows. There are two types of chemiluminescence reagents: direct luminescence reagents that are excited by the substance itself, and indirect luminescence reagents that stimulate another substance with energy from a chemical reaction. Chemiluminescence reagent. A typical example of this type of chemiluminescence reagent is luminol, which has been used to identify blood for many years. Chemiluminescence reaction caused by luminol. When a metal catalyst is present, luminol emits blue light (425 nm) in response to strong bases, oxidants (such as hydrogen peroxide) and heat. Luminol reaction can be used in HPLC to analyze peroxides (lipid peroxides, etc.) and metal-containing substances. Desheng Biochemical is a manufacturer of chemiluminescence reagents. It started in 2005 and has a private R&D team with 2 doctoral students and 6 master students. Provide consumers with chemiluminescent reagents with a purity greater than 99.3%, covering luminol/3-aminophthalic hydrazide/luminol, luminol monosodium salt, isoluminol/4-aminophthaloyl Hydrazine, acridinium ester DMAE-NHS, acridinium ester NSP-DMAE-NHS, acridinium salt NSP-SA, acridinium salt NSP-SA-NHS, acridinium hydrazide NSP-SA-ADH, acridinium ester ME-DMAE -NHS. If you have any needs, please contact us.

  Heparin salt anticoagulant represented by heparin sodium and heparin lithium is a commonly used additive for blood collection tubes. It plays an important role in the big family of blood collection tubes. In this analysis of blood collection tube additives, we will analyze the effect of heparin sodium and heparin lithium heparin salt on blood clinical testing under the condition of other factors being fixed. These factors such as the components in the blood collection tube, including the choice of anticoagulant, surfactants and separating gels, plugs, lubricants, the design of blood collection tubes or the use of blood collection equipment, etc. Let alone study the influencing factors of the anticoagulant heparin sodium and lithium heparin. Figure-Lithium heparin produced by Desheng Biochemical is ready to go It is well known that serum is used in most assays, but plasma is a useful and efficient alternative detection method due to its short processing time. Plasma containing fibrinogen and other clotting factors has a higher viscosity and total protein content than serum. The serum levels of hemagglutinin, potassium, coagulation factor activating peptide, platelet factor and platelet components released during platelet activation are high. When using plasma, the anticoagulant used to preserve the analyte may interfere with the determination of other analytes.   Heparin salts (usually from porcine intestinal mucosa) are also widely used as anticoagulants in blood collection tubes. Heparin forms a complex with antithrombin III and induces its conformational changes to accelerate the inhibition of thrombin factor, thereby preventing thrombin activation and fibrin production from fibrinogen. Heparin binds electrolytes and changes the concentration of bound ions and free ions to create an electrolyte balance formula. Heparin and citrate are the most commonly used anticoagulants. Heparin interferes with the chloride electrode membrane, creating a negative anion gap in the specimen for medical diagnosis. Heparin slows down the speed of certain antibody-antigen reactions, especially in the precipitation step in the secondary antibody system. Heparin precipitates cryofibrinogen in cryoglobulin studies. Exogenously administered heparin changes serum thyroid hormone levels. When using heparinized test tubes in hemodialysis patients, falsely low albumin levels were observed. Heparin can inhibit the binding of bromocresol green to albumin, leading to the formation of colorimetric complexes and achieving better anticoagulant effects faster. Proteomics studies have shown that heparinized plasma can cause non-specific protein binding, which affects peptide separation and mass spectrometry. Incomplete filling of lithium heparin tubes will produce higher creatine kinase and γ-glutamyltransferase activities. Desheng Biochemical has been producing heparin sodium and heparin lithium for more than ten years. Heparin salt based on heparin sodium and heparin lithium is an ideal anticoagulant for hospitals and physical examination institutions. Desheng Biochemical has an eight-person research team composed of doctoral and master students to help the development of blood testing.

Sodium fluoride heparin sodium citrate EDTA is a commonly used additive for vacuum blood collection tubes, which is commonly used for blood anticoagulation. Although the current vacuum blood collection tubes work to a large extent by design and are generally considered to be routinely recommended practices, laboratory staff must be aware of the different applications of blood collection tube additives sodium fluoride heparin sodium citrate EDTA Be particular. Which of the sodium fluoride heparin sodium citrate EDTA is used as the blood collection tube additive is particularly important. 1) Sodium fluoride Sodium fluoride inhibits the glycolytic enzyme enolase and is used to limit the in vitro consumption of glucose by cells in the collected blood samples. In fluorinated unseparated blood samples, since the upstream enzyme converts glucose into glucose 2-phosphate, glucose is still metabolized at a rate of about 5% to 7% per hour at room temperature. It may take 4 hours to completely inhibit glycolysis in a fluorine-containing test tube at room temperature. It should be noted that sodium fluoride may have enzyme inhibitory activity and is not suitable for enzyme immunoassay.   2) Heparin Sodium Heparin Lithium Heparin is a highly charged biomolecule-polymerized glycosaminoglycan. It can prevent blood clotting, but can be co-purified with nucleic acid according to the preparation method used. It is a well-known serum protein polymerase chain reaction inhibitor. If blood is collected for polymerase chain reaction analysis, it can be digested with heparinase. 3) EDTA and citrate Both EDTA and citrate are used as anticoagulants. The use of different coagulants depends on the ongoing downstream medical/biochemical analysis-such as plasma enzyme levels, etc. EDTA is a complexing agent and polymerase chain reaction inhibitor because it can complex Mg2 + ions, but extraction procedures usually result in most of the EDTA being deleted. If you want to amplify from whole blood, citrate will effectively avoid this problem. If you think there is a problem with the inhibition of the sample polymerase chain reaction, please add a known polymerase chain reaction positive sample (such as a plasmid) with the extracted target to see if it diverges. 4) Summary Blood collection tube additives are raw materials for biochemical reactions in medical equipment. Improper use by non-professionals or due to manufacturing-related problems, interference with test results related to blood collection tubes may have some impact on patient results, reduce laboratory efficiency, delay test results, and increase each time due to re-collection and re-testing The cost of testing. The optimization of blood collection tubes, the professional production capacity and standardization of suppliers are essential for reliable test analysis. Desheng Biochemical provides product support for the entire industry chain of blood collection tube additives. Sodium fluoride heparin sodium citric acid EDTA is a conventional product of Desheng Biochemical. This reminds diagnostic companies and laboratory workers to be vigilant to prevent the adverse effects of blood collection tube problems on clinical laboratory determinations.

What is carbomer? Carbomer is the common name for an ingredient called polyacrylic acid (PAA). Carbomer is a group of synthetic acrylic high molecular weight polymers that can be used as thickeners in cosmetics and skin care products. They are mainly added to gel-like formulas such as facial moisturizers, sunscreens, shampoos, anti-aging formulas, cleansers and scrubs to help control the thickness, fluidity and consistency of the product.   Carbomer polymers can be present in a variety of product types, including skin, hair, nails, and cosmetics, at concentrations up to 50%. You may notice a number related to the carbomer name on the ingredients, which is the carbomer code. The carbomer codes (ie 910, 934, 940, 941, and 934P) indicate the molecular weight and specific composition of the polymer. Carbomer polymers can have varying pH values ​​and must be neutralized to make them function as thickeners. Formulas containing carbomer polymers sometimes list these neutralizers. Examples include triethanolamine (TEA), sodium hydroxide, potassium hydroxide and tetrasodium EDTA, to name a few. At other times, the company will purchase pre-neutralized carbomers, which may or may not list neutralizers. Why use Carbomer? To understand the functions of carbomers, it is important to first understand how they work. When carbomer is placed in an aqueous solution of neutral pH, many side chains will lose protons and gain a negative charge. Due to this reaction, carbomer is able to absorb and retain water, and swell to many times its original volume. This is why carbomer is considered a texture enhancer and is used to increase the thickness of products (especially gel formulations). In addition, Carbomer has the ability to disperse or suspend insoluble solids in liquids. Therefore, carbomer is used to prevent the separation of emulsions into oil and liquid components, as well as to control the consistency of cosmetics and other skin care products. By adding carbomer to shampoo, conditioner, cream and lotion, the formula will appear richer, smoother and creamy.   By changing the amount of carbomer in the product, formulators can use hard hair sprays, hard hair sprays that can keep the body flowing but still flow easily, or rich creams that can keep the shape to make anything. A large amount of carbomer in the gel may cause the makeup to roll or pilling on the skin, but this phenomenon depends on other formulation steps to minimize this effect. Desheng Biochemical specializes in the production of carbomer's raw materials, which are white fluffy powders, which can be used to prepare various daily chemicals according to actual uses. At the same time, the company has a research and development team of 2 doctoral students and 6 master students to help the downstream enterprises' customized needs.

Tris(hydroxymethyl)aminomethane is a synthetic biological buffer for skin care and cosmetics. It can be used as a pH buffer regulator and fragrance ingredient. Tris(hydroxymethyl)aminomethane, also known as tris, is an organic amine proton acceptor. It is commonly used as a component of buffer solutions in biochemistry and molecular biology. Basically, the role of tris(hydroxymethyl)aminomethane is to improve stability and efficacy by adjusting the pH or acidity of the product. Tris is also used in the synthesis of surfactants and drugs, as well as mineral oil and paraffin emulsions, leather dressings, and special textile products as polish cleaners and emulsifiers. Advantages: Tris can improve stability and efficacy by adjusting the pH or acidity of the product. Tris is considered safe for its intended use and is not irritating or allergic to the skin.   What is the effect of tris(hydroxymethyl)aminomethane? Why does it appear in cosmetics and skin care products? The FDA reported the use of butyl triamine in 488 disposable products and 70 disposable products. It is used in disposable nail polishes and lotions as high as 3.7%. Other products include eye makeup up to 2%, fragrance formulations up to 0.2% and formulations up to 3.1%. Tris(hydroxymethyl)aminomethane can be used to establish and maintain the pH of the product. pH stands for "potential hydrogen" and it refers to the level of acidity or alkalinity in a given solution. The pH value ranges from 0 to 14. A pH of 7 is neutral. A pH of less than 7 is acidic. A pH greater than 7 is alkaline. The effective buffer range of tris(hydroxymethyl)aminomethane is 7 to 9. The normal pH of the skin is weakly acidic, usually between 4.7 and 5.75. Sebaceous glands maintain sweat glands and normal skin flora. The acid film provides a layer of amino/lactic acid and oil film, which can effectively protect the skin from environmental factors (such as bacteria, pollutants and water loss), which can cause premature aging and irritation. The pH of cosmetics and skin care products is important to maintain the normal pH of the skin as much as possible. If the product is too sour, it may irritate the skin or cause a tingling sensation. Products that are too alkaline are harmful because they deplete important natural fats or lipids in the skin. The cracked acid skin layer will also not allow the product to be absorbed into the skin. This is why pH adjusters (such as tris(hydroxymethyl)aminomethane) can be used in cosmetic formulations. Desheng Biochemical Technology Co., Ltd. specializes in the production and research of tris and carbomer. These are the main components of daily chemical products, which are basically used in the daily chemical industry. At the same time, it is also chemical as a PH regulator in organic synthesis. Common preparations for reactions. The company has a R&D team with 2 doctoral students and 8 masters, providing Tris and Carbomer R&D services for related industries.