China Wuhan Desheng Biochemical Technology Co., Ltd Company News

Heparin sodium, as a commonly used Anticoagulant in clinic, can not only be added to blood collection vessels to prevent blood coagulation, but also can be used as a drug to effectively prevent thrombosis and reduce the incidence of cardiovascular and cerebrovascular diseases. According to different preparation methods and structural characteristics, heparin sodium can be divided into various types. Next, we will introduce the classification of heparin sodium in detail.   Classification according to preparation method   1. Natural heparin sodium: a Natural product mainly extracted from pig intestines, bovine lungs and other animal viscera. After complete extraction of heparin, it is refined to obtain heparin sodium with high purity. Its production requirements are strict, and it is usually added to the blood collection vessel for use, with relatively stable performance.   2. Synthetic heparin sodium: obtained through chemical synthesis, it has high yield and cost advantages. Currently, polymer method and metal organic compound method are mainly used in the market for synthesis, and its performance and usage are far inferior to the first naturally prepared heparin sodium.   Classification based on structural features   1. Ordinary heparin sodium: Ordinary heparin sodium is a high molecular weight heparin containing multiple repeating units, appearing in the form of a drug. Its anticoagulant effect is good, but its bioavailability is low, and it is prone to side effects. It is rarely used in clinical practice.   2. Low molecular weight heparin sodium: Low molecular weight heparin sodium is a short chain heparin obtained through chemical modification, with high bioavailability and suitable for intravenous injection. Due to its direct contact with the human body, it not only requires high production requirements and expensive prices, but also requires obtaining corresponding certificates before production, and is subject to the supervision of the Medical Commission.   3. Heparin sodium salt: it is a kind of raw material heparin sodium, which is mainly extracted from pig intestinal mucosa, and then obtained through ion exchange adsorption. Its average molecular weight is about 15000, and its potency is between 150IU-180IU. It is generally of non injection grade. It is prepared into a solution and added to the blood collection vessel as an in vitro Anticoagulant.   Classified by purpose   1. Medical heparin sodium: medical heparin sodium includes medical heparin sodium and extracorporeal Anticoagulant heparin sodium, which are mainly used in cardiac surgery, hemodialysis, vascular interventional therapy and other fields, with strong anticoagulant effect and therapeutic effect. While the external Anticoagulant heparin sodium is used clinically, the main purpose is to help blood coagulate quickly in blood collection and improve the inspection efficiency of medical staff.   2. Industrial heparin sodium: This type of heparin sodium is generally low in purity, contains impurities, has low production requirements, and is cheap. It is mainly used in the manufacturing of industrial products such as cellulose and paper.   Different types of heparin sodium have different characteristics and application ranges, and selecting the appropriate type of heparin sodium needs to be considered based on the specific usage. As a professional manufacturer of heparin sodium, Desheng's product type is analytical pure heparin sodium salt, which is mainly used as an in vitro Anticoagulant and cannot be used for human body. If you are interested, you can indicate the use needs in advance to facilitate customer service to give you accurate quotations. Feel free to contact us at any time.

Heparin sodium is an important chemical reagent that can be widely used as an additive for blood collection in clinical medicine, and also has a certain role in scientific research. The high level of its popularity represents market demand, which inevitably varies in price and is affected by various factors, such as production process, price, and manufacturer scale. Let's take a look at the factors that affect the price of heparin sodium per kilogram?   1. Production process: Heparin sodium is a reagent obtained by fine extraction and purification of natural heparin. Its production process is complex and requires advanced technology and equipment. The high investment in equipment increases costs, and the price of heparin sodium will also be affected.   2. Raw material cost: Its production requires a large amount of raw materials, including heparin from animals (such as pig intestinal mucosa). However, incomplete statistics are required. Only 3000 pigs can extract 1kg of heparin. If the number of live pigs is small, it is also an important factor affecting the price of heparin sodium.   3. Production scale: Production scale is another important factor affecting the price of heparin sodium. Mass production can reduce the production cost per unit product, thereby lowering the price of the product. Therefore, generally larger manufacturers are able to provide more competitive prices.   4. Market competition: As a commonly used Anticoagulant, the market competition is fierce, and the competition between different manufacturers will also affect the product price. In a highly competitive market, manufacturers may lower product prices to compete for market share.   5. Quality certification and standards: As a clinical reagent, heparin sodium must comply with strict quality certification and standards. Products that have passed quality certification and compliance standards are usually priced higher, but their quality and safety are also more guaranteed.   As an important Anticoagulant, heparin sodium is widely used in clinical medicine and scientific research. Its price per kilogram is affected by many factors. When choosing heparin sodium suppliers, in addition to price, everyone should also pay attention to product quality and supply capacity to ensure that the purchased products are safe, reliable, and meet the requirements.   As a raw material manufacturer of blood vessel additives, Desheng has always pursued quality first, so it strictly controls the quality of heparin sodium in the upper layer, fully protecting customer rights and interests. As a manufacturer, it can negotiate prices based on quantity, and the more orders placed, the greater the discount. If you are interested, please feel free to contact us for purchase!

Nowadays, with the improvement of living standards, people are paying more and more attention to their physical health status, and the demand for physical examinations is also increasing. During a physical examination, blood analysis is a necessary item to be checked. When carefully observing the blood collection vessels, it can be observed that each type of blood collection vessel cap has a different color. This is because different reagents are added to tubes of different colors, such as blood collection tubes with Anticoagulant, coagulant and no reagent.   At present, the widely used reagent is Ethylenediaminetetraacetic acid dipotassium salt, which is one of the Anticoagulant and can prevent blood coagulation. However, the basis for its effectiveness depends on performance, such as molecular weight, pH value, solubility, or main content. So next, let's introduce this aspect to everyone.   Properties of dipotassium Ethylenediaminetetraacetic acid   Its appearance is white crystalline powder, without a pungent odor, and is easily soluble in water. As the finished product is a powder, it is easy to absorb moisture, with an average molecular weight of 404.6 and a pH value of 4.8 ± 1 in a 5% aqueous solution. The solubility in water is ≥ 60%, and it is of analytical purity grade, with a main content of over 99%. Adding it as a solution to a test tube has strong stability and can effectively protect blood components from damage.   Anticoagulant mechanism of dipotassium salt of Ethylenediaminetetraacetic acid   Because it needs to be prepared into a solution when added to a vacuum test tube, Ethylenediaminetetraacetic acid and Ethylenediaminetetraacetic acid anions can be dissociated on this basis. They can effectively chelate calcium ions in the blood, control calcium ion reaction from the source, prevent internal and external coagulation process, so as to achieve the purpose of blood coagulation and inhibit platelet aggregation. At the same time, compared with other anticoagulants of the same type, Ethylenediaminetetraacetic acid dipotassium has the smallest effect on blood cell composition and high solubility, so it is also a rational Anticoagulant that is highly respected in medicine.   Determination of pH value, main content, and solubility   In addition to the molecular weight that can represent the overall mass of Ethylenediaminetetraacetic acid dipotassium salt, the pH value, main content and solubility are also important. The measurement method is as follows:   1. Determination of main content: weigh an appropriate amount of sample, add water and ammonium chloride solution to fully stir and dissolve, then add an appropriate amount of Eriochrome Black T indicator, titrate with Zinc chloride standard titration solution until the solution turns red and purple, and then calculate the content according to the calculation formula. Desheng Ethylenediaminetetraacetic acid dipotassium salt is a dihydrate, so the main content may be higher than 100, which is normal.   2. PH measurement: Dissolve an appropriate amount of the sample to be tested in pure water, stir at room temperature for about 5 minutes, and then use a pH meter to measure it.   3. Solubility measurement: Take an appropriate amount of the sample to be tested and dissolve it in pure water. Stir at room temperature for 5-10 minutes to observe if it is completely dissolved.   As a superior supplier of Ethylenediaminetetraacetic acid dipotassium salt, Desheng has not only high purity and stable performance, but also independent production lines and large warehouses for spot sale. If you are interested, please click the website for consultation and purchase!  

Heparin sodium is an important biomedical compound that, as a polysaccharide compound, has anticoagulant and anti-inflammatory effects and is widely used in clinical medicine and laboratory research fields. Due to its special role in medical and life sciences, it is important to have a deep understanding of its structure, uses, and characteristics. Below, we will give you a specific introduction around this aspect.   Molecular structure and chemical properties   Heparin sodium is a polysaccharide compound, which is composed of monosaccharide units such as Glucuronic acid and N-acetylglucosamine. Its main feature is that the molecular chain contains Organosulfate groups, which endow heparin sodium with strong anticoagulant ability. Because of its complex and diverse molecular structure, heparin sodium has broad application prospects in the medical field.   The use of heparin sodium liquid   Heparin sodium can be prepared as a drug or used as an additive, and its drugs are commonly used in clinical anticoagulation therapy, prevention and treatment of thrombosis. In cardiovascular surgery, hemodialysis and Pulmonary embolism, heparin sodium liquid is used for intravenous injection to reduce blood coagulation and prevent thrombosis. The additive, on the other hand, dissolves the original powder, then sprays it onto the inner wall of the test tube and dries it. It performs anticoagulant treatment on blood samples in vitro and is suitable for various biochemical tests, such as liver and kidney function testing.   The main characteristics of heparin sodium   1. Anticoagulant properties: The main characteristic of heparin sodium is its powerful anticoagulant effect, which inhibits blood coagulation reactions by binding with anticoagulant factors, thereby reducing the risk of clinical occurrence.   2. Safety: Heparin sodium injection liquid is widely used in clinical practice, and its safety has been fully verified. However, during use, attention should be paid to dosage and medication monitoring to prevent potential adverse reactions.   3. Stability: The solution is stored in a cool and dry place, not exposed to air, and has good stability.   Heparin sodium, as an important anticoagulant reagent and laboratory reagent, plays a crucial role in the fields of medicine and life sciences. To ensure its safety and effectiveness, attention should be paid to the dosage, usage, and storage conditions when using heparin sodium.   As the raw material manufacturer of heparin sodium, Desheng has strict requirements on its solubility and simple preparation, but it should be noted that its heparin sodium is used as a Anticoagulant for blood collection and cannot be used as a drug to treat any disease. If you have the need to purchase heparin sodium raw materials, please feel free to contact us for purchase!

Heparin sodium is often used as a Anticoagulant in blood collection vessels. It can effectively prevent blood clotting and ensure that the collected blood sample remains liquid in proper time to provide accurate detection results. So how should it be used and what are the advantages of using it? Below, we will provide a specific analysis around this aspect to help everyone better understand and correctly use heparin sodium as an additive for blood collection.   Usage method   1. Addition method: Due to the original nature of heparin sodium as a powder, it needs to be prepared into a solution and added to a test tube. It can be dissolved in deionized water, and mixed evenly after the volume is fixed. After checking that the relevant values meet the standards, the machine can be used to adjust the parameters before adding. It can be coated in small batches on the inner wall of the blood collection vessel to ensure uniform distribution.   2. Dose added: the standard range of heparin sodium used in Vacutainer is 12-30IU per milliliter of blood. If it is micro blood collection, it should be reasonably adjusted according to the volume and type of blood collection vessel to ensure proper anticoagulant effect.   Advantages of heparin sodium in blood collection vessels   Heparin sodium can effectively prevent blood clotting, maintain the state of blood samples, and ensure the stability of blood components. Meanwhile, due to its widespread clinical application and long-term validation, it has a certain degree of safety and will not affect blood samples. In addition, after anticoagulation treatment with heparin sodium, it can be applied to a variety of tests, including routine Blood test, biochemical analysis and immunological tests. During the process of blood preservation, it can prevent the blood sample from being damaged by external influences.   Precautions for use   1. Dose control: The dosage of heparin sodium should be adjusted based on the volume and type of blood collection vessel to avoid excessive use.   2. Storage conditions: Heparin sodium raw material powder should be stored in a dry and cool place, avoiding direct sunlight and high temperatures.   3. Inverted mixing: To ensure sufficient coagulation of the blood sample, it should be inverted and mixed as soon as possible after blood collection, especially when the ambient temperature exceeds 25 degrees Celsius. Timely operation is necessary.   4. Due to the non irreversible anticoagulation of heparin sodium tubes, testing should be completed within 6 hours after blood collection is completed as soon as possible, otherwise it may lead to errors in the results.   As an additive for blood collection, heparin sodium plays an important anticoagulant role in the blood collection process, ensuring the stability and accuracy of blood samples collected. When using, attention should be paid to the dosage and storage method. Proper use and handling of heparin sodium can help improve the safety of the blood collection process and the quality of blood samples.   As a professional supplier of heparin sodium, Desheng can not only provide high-quality products, but also offer more favorable prices in large quantities, especially for customers who purchase in batches. It can achieve significant discounts. If you are interested, please feel free to contact us for purchase!  

Heparin sodium is an important Anticoagulant. Based on the anticoagulant principle, it can be used for both external and internal anticoagulation. No matter what type of anticoagulation, it needs to rely on the quality of heparin sodium. The prerequisite for controlling quality is to have excellent production and strict requirements at the source. In this regard, the following will focus on introducing the extraction of heparin sodium and related application precautions.   Extraction method of heparin sodium   According to research, there are various methods for extracting heparin sodium, among which the most common are the following three：   1. Animal derived heparin extraction: Heparin is mainly extracted from the lungs, intestines, and other tissues of animals (such as cows, pigs, etc.), and then subjected to enzymatic hydrolysis, precipitation, washing, and purification steps to prepare heparin sodium for use. This is also a commonly used extraction method by most manufacturers at present.   2. Fermentation method: Large scale fermentation production is carried out by microorganisms (such as fermentation bacteria), and heparin is extracted from the heparin binding substance in the culture medium. This method is relatively rare and generally requires low production requirements.   3. Synthetic method: In recent years, with the development of chemical technology, the method of artificially synthesizing heparin has gradually matured, and heparin can be obtained through synthetic methods. This method is generally used by more mature manufacturers, and its production process is relatively complex.   Application of heparin sodium   1. Anticoagulant therapy: As a Anticoagulant, heparin sodium can be prepared into drugs and widely used in the prevention and treatment of cardiovascular diseases, Deep vein thrombosis and other diseases. Thrombosis can be prevented by inhibiting the activity of coagulation factors.   2. Blood anticoagulation treatment for blood collection: This anticoagulation is generally performed in vitro and mainly affects the blood. Blood treated with heparin sodium is suitable for various routine examinations in clinical practice.   3. Laboratory research: Heparin sodium is also used in certain experiments in biomedical research, such as blood agglutination inhibition experiments.   Precautions for extracting heparin sodium   1. High purity requirements: As a Anticoagulant, the purity and quality of heparin sodium are very important. During the extraction process, each step needs to be strictly controlled to ensure that the purity and quality of the product meet the standard requirements.   2. Optimization of reaction conditions: In response to the requirements of extraction methods, it is necessary to optimize reaction conditions, such as temperature, pH value, enzyme selection and concentration, in order to achieve high extraction efficiency and purity.   3. Extraction process monitoring: During the extraction process, key parameters such as heparin content and coagulation time should be regularly monitored to ensure the effectiveness of the extraction.   By using reasonable extraction methods and strict quality control, high-quality heparin sodium products can be obtained. Desheng, as a professional manufacturer of heparin sodium, is mainly extracted from the small intestinal mucosa of pigs, which is made into heparin sodium raw material and used as an in vitro Anticoagulant in test tubes. If you are interested, please contact us to purchase!

Heparin sodium is a commonly used in vitro Anticoagulant, which is widely used in clinical medicine and laboratory research. Understanding the validity period of heparin sodium is of great significance in ensuring its safety and effectiveness. Therefore, clinical blood testing can also avoid many troubles and further protect the rights and interests of patients. Therefore, we will analyze the validity period of Anticoagulant heparin sodium and its importance in the use process.   Validity period of heparin sodium   Usually, after the production of heparin sodium raw materials and finished products, the expiration date is indicated by the manufacturer's trademark, which is generally determined based on factors such as reagent stability, storage conditions, and safety of use, and is around 1-3 years. As long as it is used and stored properly during this period, there will be basically no degradation phenomenon, leading to reagent performance failure or weakening.   The importance of the validity period of heparin sodium   1. Anticoagulant effect: The validity period of heparin sodium is closely related to its anticoagulant effect. Expired heparin sodium may weaken the anticoagulant effect, affecting the stability and accuracy of blood anticoagulation.   2. Safety: Within the validity period, heparin sodium has undergone strict quality control and safety assessment, making it more reliable and safe to use. Expired heparin sodium may pose safety hazards, such as the generation of reagent degradation products or microbial contamination.   3. Quality control: Validity period is a part of quality control in the production process of heparin sodium, which ensures stability and consistency within the validity period and is also a key factor in evaluating the quality of its products. The correct selection and rational use of heparin sodium within its validity period can help to obtain reliable in vitro anticoagulant effects.   Recommendations for storage and use of heparin sodium   1. Storage conditions: Heparin sodium should be stored in a dry and cool place, avoiding direct sunlight and high temperature environments. Correct storage conditions can help extend the shelf life of heparin sodium.   2. Strictly follow the expiration date: When using heparin sodium, it is necessary to comply with the production regulations and avoid using expired products.   3. Product quality: Before using or purchasing heparin sodium, the expiration date on the packaging should be checked, and the appearance, color, and clarity of the prepared solution should be carefully observed to ensure that the quality of heparin sodium meets the standard.   Understanding the validity period of heparin sodium is crucial for ensuring the accuracy of usage results, and it is important to focus on understanding it when purchasing. As a raw material manufacturer of blood vessel additives, Desheng's heparin sodium products not only have high main content, but also have a pure appearance, which can be used for on-site visits and inspections by customers. The current customers who have used the product have all had secondary repurchases and are highly praised. If you are also interested, please click on the website to contact us!

Heparin sodium is a commonly used chemical substance with a wide range of applications. It can not only be used as a drug in vivo, but also can be used as a blood Anticoagulant in vitro, mainly by inhibiting the activity of thrombin and other coagulation factors to prevent blood coagulation. Below is a detailed introduction to the main functions and application fields of heparin sodium.   1、 Anticoagulant effect   Heparin sodium enhances its activity by binding to antithrombin III, thereby inhibiting the formation of thrombin, which can prevent the formation of blood clots. In addition, heparin sodium can further enhance its anticoagulant effect by inhibiting the activity of other coagulation factors, such as thrombin factor Xa.   2、 Blood collection and processing   After being configured as a solution, it is mainly added to a vacuum test tube. When in contact with blood samples, it can inhibit blood coagulation in the test tube, thereby ensuring the stability of the blood collection environment and improving the collection and processing efficiency of medical staff. It generally does not come into direct contact with the human body and will not have any side effects on the human body.   3、 Prevention and treatment of venous thromboembolism   Venous thromboembolism is a serious thrombotic disease, including Deep vein thrombosis (DVT) and Pulmonary embolism (PE). Heparin sodium injection can be used to prevent and treat these conditions, especially in surgery, prolonged bed rest, and high-risk patients. It usually comes into contact with the human body, and its level and purity requirements are high. Generally, manufacturers without qualification certificates are not allowed to produce and sell it.   4、 Hemodialysis and cardiac surgery   Heparin sodium is also commonly used in hemodialysis as a Anticoagulant to prevent thrombosis in dialysis devices and blood vessels. The Anticoagulant during dialysis needs to maintain appropriate anticoagulant effect to ensure the normal circulation and filtration of blood in the dialyzer. In cardiac surgery, heparin sodium is commonly used as anticoagulant therapy to prevent the formation of blood clots during and after surgery. It is usually used in combination with other Anticoagulant (such as Warfarin) to achieve better anticoagulant effect.   5、 Other application areas   Heparin sodium can also be added to daily chemicals to have antioxidant, anti-inflammatory, and promoting blood circulation effects. At the same time, it can not only protect the skin from damage, slow down skin aging, but also reduce skin redness, swelling, inflammation, and increase skin metabolism, thereby improving the poor condition of the skin.   Heparin sodium, as an important anticoagulant, has a wide range of applications. Its anticoagulant effect is achieved by inhibiting the activity of thrombin and other coagulation factors. However, when using, it is also important to pay attention to the amount of addition, and not too much or too little, otherwise it will cause changes in the results. As a professional supplier of heparin sodium, Desheng mainly provides blood collection additives and uses in vitro anticoagulant reagents. If you have any raw material requirements, please feel free to contact us for purchase!

Heparin Sodium is a Anticoagulant widely used in clinical and research fields. It has a long and rich history and originated in the early 20th century. In 1916, an American biochemist named Jay McLean first extracted an anticoagulant substance from pig lungs. He noticed that this substance had the effect of prolonging the clotting time of animal blood, and later became known as heparin.   1、 Naming of Heparin   McLean initially named this substance 'Heparin', which comes from the Greek word 'hepar'. He chose this name because at the time he believed that the liver might be the main source of heparin.   2、 Development of clinical applications   In 1935, American biochemists Karl Meyer and John M. Morehead successfully applied heparin to clinical anticoagulation therapy for the first time. They found that heparin can prevent and treat thrombosis and improve postoperative blood circulation.   3、 Discovery and Research Purification of Heparin Sodium   In 1939, Meyer and Morehead successfully extracted purer heparin through further research, which made the production and application of heparin more feasible and effective. Therefore, in the 1950s, researchers began to transform heparin into heparin sodium to improve its solubility and stability. It has a series of chemical properties and is widely used in clinical blood collection as an extracorporeal blood Anticoagulant.   4、 Improvement of preparation and production technology   Over time, the preparation and production techniques of heparin sodium have been continuously improved and optimized. By improving the extraction, purification, and crystallization processes, the purity and quality of heparin sodium have been improved. So its application fields are also constantly expanding. In addition to anticoagulant therapy and in vitro anticoagulant blood processing, heparin sodium is also widely used in fields such as cardiac surgery, hemodialysis, and laboratory research.   As an important Anticoagulant, heparin sodium has a long history and rich research results. Its discovery and development have gone through multiple stages, from the discovery of heparin to the preparation and technological improvement of heparin sodium, which has been widely applied in various fields, providing important support for improving detection efficiency and accuracy of results.   As a professional manufacturer of heparin sodium, Desheng has always been committed to providing high-quality heparin sodium raw material products and high-quality services. The company not only possesses advanced production equipment and technology, strictly controls the quality of each link, but also provides comprehensive technical support and after-sales service to help customers solve various problems and needs in a one-stop manner. If you are interested, please feel free to contact us for purchase!

Heparin sodium salt is a commonly used Anticoagulant, which is widely used in clinical medicine and biochemical experiments. It has good anticoagulant effects, achieving the goal of preventing blood coagulation by inhibiting the activity of thrombin and other coagulation factors. Generally supplied in the form of powder, the dissolution of heparin sodium salt is a prerequisite for its use, and its solubility directly affects the stability and effectiveness of the reagent. Therefore, understanding the dissolution method of heparin sodium salt is crucial. Below, we will focus on introducing the dissolution method.   1、 Solvent selection   When dissolving heparin sodium salt, it is necessary to choose a suitable solvent. In general, deionized water and distilled water are the most commonly used solvents, and their pH and ion concentration are close to those of human blood, without significantly affecting the properties of the solution.       2、 Dissolution temperature   Temperature is an important factor when dissolving heparin sodium salt. Normally, heating the solvent to an appropriate temperature can accelerate the dissolution rate of heparin sodium salt, but this operation is carried out under special circumstances. The commonly used operations are to dissolve at room temperature, usually not exceeding 45 degrees Celsius, to avoid reducing the stability of the solution or causing the decomposition of heparin sodium.   3、 Mixing and dissolution time   After adding the solvent, sufficient stirring is required to promote the dissolution of heparin sodium salt. Stirring can increase the contact area between it and the solvent and accelerate the dissolution rate. It is recommended to use appropriate stirring equipment or methods, such as Glass rod, and continue stirring for a period of time until heparin sodium salt is completely dissolved. The dissolution time depends on its form and the properties of the solvent, usually within 10 minutes.   4、 Filtering and Storage   The completely dissolved heparin sodium salt solution can be filtered to remove insoluble substances and impurities. Use appropriate filtration devices and membranes to filter the solution into a clean container to obtain a clear solution. In addition, the storage of solutions is also very important. Generally, solutions should be stored under refrigeration conditions to ensure their stability and long-term preservation.   Dissolving heparin sodium salt is a prerequisite for its use, and the correct dissolution method is crucial to ensure the stability and effectiveness of its solution. The correct dissolution method can ensure the stability of solution quality and performance, thereby ensuring the effective use of heparin sodium salt. At the same time, when using, pay attention to referring to the manufacturer's production and preparation suggestions and guidance.   As a supplier of raw materials for blood vessel additives, Desheng can effectively meet the needs of various products and provide professional guidance to help customers use them efficiently. If you are interested, please click on the website to contact us anytime to purchase!

Anticoagulant is a kind of reagent commonly used in medical and biological fields to prevent blood coagulation. Among them, pig heparin and heparin sodium are very common in the market. Although they appear similar on the surface, there are certain differences in structure, source, characteristics, and application. Below, we will compare and analyze pig heparin and heparin sodium to help you further understand the differences between the two.   1、 Structure and Source   Hoggarin is a natural polysaccharide Anticoagulant, which is mainly extracted from pig intestinal mucosa. Its main component is a mixture of heparin sulfate and other sulfate polysaccharides. Heparin sodium is a synthetic Anticoagulant, and its structure is similar to natural heparin. But its preparation is generally achieved by extracting heparin from animal (such as pig) mucosa, and then chemically modifying and refining it.   2、 Molecular weight and properties   The molecular weight of pig heparin is relatively large, usually ranging from 3000 to 30000 Daltons. It has anticoagulant activity and can inhibit coagulation reactions by forming complexes with coagulation factors and antithrombin. However, the molecular weight of heparin sodium is relatively small, usually around 15000 Daltons. However, it also has anticoagulant activity, usually by forming a complex with thrombin to block the coagulation process.   3、 Anticoagulant mechanism   Porcine heparin blocks the activity of thrombin by binding to thrombin and coagulation factor Xa, thereby inhibiting blood coagulation. Heparin sodium plays an anticoagulant role mainly by combining with thrombin and antithrombin III (AT-III). It can improve the anticoagulant activity of AT-III and inhibit the formation of thrombin.   4、 Application field Porcine heparin is mainly used in cardiovascular surgery, dialysis treatment, and the prevention and treatment of thrombotic diseases. It is also used as a Anticoagulant in laboratory research. Heparin sodium is usually used as extracorporeal blood Anticoagulant in blood collection vessels, and is suitable for liver and kidney function testing, blood glucose and routine biochemical testing.   Although both porcine heparin and heparin sodium are Anticoagulant, they are different in structure, source, characteristics and application. The choice of anticoagulant to use should be based on actual needs, and attention should be paid to the amount used during the use process. Excessive or insufficient use can have an impact on the experimental results. As a professional supplier of heparin sodium, Desheng produces products with analytical purity, which can be added to test tubes for use as extracorporeal blood Anticoagulant. After strict quality control and testing, it ensures compliance with customer standards and requirements, and is deeply trusted and praised by customers. If you are interested, please feel free to contact us for purchase!

Heparin Sodium is a commonly used Anticoagulant, which is widely used in the medical field. As the original powder of Anticoagulant, it can be prepared into a solution and added to test tubes for blood collection. If it is prepared into a drug form, it can be used in hemodialysis and surgery. There are also differences in the usage methods of different applications, and we will introduce them specifically below.   Use of heparin sodium raw material powder   1. Solution preparation   Prepare Volumetric flask, balance, beaker, deionized water, bottle washing and other appliances, weigh the prepared heparin sodium powder in advance, and then pour the powder into the beaker. Pay attention to the cleanliness of the appliances, which shall be free of impurities and bacteria. Then use deionized water to dissolve it. Add water and stir it slowly with Glass rod, and transfer it into a volumetric flask after it is completely dissolved. After dissolution, it is necessary to perform a constant volume to keep the liquid level consistent with the scale line, and finally mix and check for confirmation.   2. Solution addition   Although it is divided into manual addition and machine addition, in order to save time and improve the efficiency of producing finished products, most people will choose machine addition. Before using the machine, ensure that all adding pipelines are in a sterile state, clean them with ethanol, dry them with hot air, and then adjust the machine to the corresponding value to add liquid.   3. Drying   Generally, test tubes are dried using methods such as a drying oven or drying room. The hot air drying temperature is generally controlled at around 50-80 degrees Celsius, and the time is 10-300 seconds. The drying time and temperature can be adjusted according to the volume of the solution and the exhaust capacity, and the wind speed should not be too high.   Heparin sodium drug use   1. Before using heparin sodium drugs, make sure to understand the required dosage beforehand and prepare appropriate drugs and equipment according to the requirements. At the same time, check whether the packaging of heparin sodium is intact, pay attention to the expiration date and storage conditions, and ensure the quality and usability of the drug.   2. The common dosage form of heparin sodium is injection, and appropriate dosage forms should be selected according to needs. For patients undergoing hemodialysis treatment, heparin sodium is used to anticoagulate the blood circuit and prevent blood from clotting in the dialyzer. The dosage of heparin sodium should be adjusted based on the patient's weight, dialysis time, and dialyzer type. In addition, heparin sodium is used as an intraoperative Anticoagulant in cardiac surgery or vascular surgery. According to the nature and needs of the surgery, the dosage and method of using heparin sodium need to be determined based on factors such as the patient's weight, coagulation indicators, and surgical plan.   As a commonly used Anticoagulant, heparin sodium plays an important role in medical and laboratory applications. When using heparin sodium, it should be fully prepared and operated according to the correct use method and dosage. As a superior supplier of heparin sodium, Desheng's products are white powder with high main content, and are mainly used in blood collection vessels as extracorporeal blood Anticoagulant. If you have any interest, please feel free to contact us for purchase!