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Latest company new about Why EDTA Tripotassium is used in blood collection
2022/11/22

Why EDTA Tripotassium is used in blood collection

Why EDTA Tripotassium is used in blood collection?   As a potassium salt, tri potassium EDTA can chelate with most metals to form a stable chelate, so it is often used as a chelating agent in various products. The most common application is in blood collection. It is added to blood collection tubes to play the role of blood anticoagulation. Although EDTA tri potassium is widely used, many people still do not know why it is used in blood collection. So, let me introduce it to you in detail.   1、 Performance of EDTA tripotassium The use of EDTA tri potassium in blood collection is determined by its performance. As a potassium salt, it has its own chelating property. It can chelate calcium ions, sodium ions, magnesium ions and other metal substances together without reaction. After the blood sample is drawn, the blood sample contains calcium ions. In the process of full contact, tri potassium EDTA will immediately play its own chelating property, blocking the coagulation function from the source, so that the blood will not clot in a certain time, improving the detection efficiency.   2、 International recognition In 1993, the International Blood Standards Committee recognized that tri potassium EDTA could be used as an anticoagulant for blood analysis, and vigorously promoted its first use. In the era of fully automated medicine, the popularity of EDTA tri potassium not only provides convenience for medical personnel and shortens the detection time, but also avoids the error of detection results and waste of medical resources to a certain extent.   3、 Simple and convenient configuration Generally, in order to facilitate transportation and storage, many raw material manufacturers produce EDTA trisotassium in powder form, which is not directly added to the test tube, so it needs to be prepared into a solution before use. The solution added to the blood collection tube needs to meet the key indicators and be easy to operate. On the premise of ensuring the solubility, it is only necessary to dissolve the EDTA potassium trioxide powder with deionized water. After the solution is injected into the test tube, it can be dried. The configuration process is simple, which is conducive to rapid supply and blood collection, and is the unanimous choice of everyone.   Desheng Biochemical is a professional manufacturer of blood collection reagents. The EDTA series products manufactured, such as EDTA dipotassium/tripossium/disodium, are of high purity and excellent performance. They are analytical pure grade and are supplied to downstream reagent manufacturers for a long time. The factory is equipped with advanced equipment, independent warehouse and stable supply. If you have relevant needs, please click the website or call for details!
Latest company new about What is the purity test method of potassium ethylenediaminetetraacetate?
2022/11/22

What is the purity test method of potassium ethylenediaminetetraacetate?

What is the purity test method of potassium ethylenediaminetetraacetate?   Bottled EDTA dipotassium ethylenediaminetetraacetic acid dipotassium is called EDTA-2K for short. As an anticoagulant commonly used in blood collection vessels, its anticoagulation performance is good, so it is favored by many downstream reagent manufacturers and medical institutions. At the same time, there are more and more factories producing potassium ethylenediaminetetraacetate in the upstream, the quality becomes uneven, and many inferior products are mixed in.   The so-called "inferior" products refer to unstable performance, low purity and appearance defects. Among so many products with poor quality, how should buyers identify them?   The key to determine the performance of potassium ethylenediaminetetraacetate is its purity, pH value, clarity, solubility and impurities. Therefore, special attention should be paid to these aspects, and testing can be conducted if necessary to avoid purchasing products with poor performance. So, what is the purity test method of potassium ethylenediaminetetraacetate? Next, I would like to give you a detailed introduction.   1. Purity test Weigh 0.1g of EDTA potassium sample, accurate to 0.0001g if necessary, add 70mL of water and 10mL of ammonia ammonium chloride buffer solution with pH value of about 10. After the sample is fully dissolved, add 5 drops of chrome black T indicator, 5g/L, and titrate with zinc chloride standard titration solution until the solution turns red purple [c (ZnCL2)=0.025mol/L].   The purity of potassium ethylenediaminetetraacetate produced by Desheng is higher than 100, which is a normal phenomenon, because the company's potassium ethylenediaminetetraacetate is a dihydrate, and the main content detected contains two crystal water.   2. PH value test Weigh 5g of test potassium sample, dissolve it in 100ml of pure water, stir for about 5min at room temperature, and test the PH value. The pH value of Desheng's potassium is 4.8 ± 1 (5% aqueous solution, g/ml). 3. Clarity test   Weigh 20g of test sample, dissolve it in 100ml of pure water solution, stir it for 5-10 minutes at room temperature, and compare the prepared water solution with colorless transparent liquid.   4. Solubility test Weigh 60.0g of the sample to be tested, dissolve it in 100ml of pure water, stir for 5-10 minutes at room temperature (25 ± 5 ℃), and observe the dissolution.   5. Impurity test Place 0.22 filter membrane in the testing vessel, pour the solution into the filter, and observe whether there are impurities on the filter membrane and whether there are too many impurities.   The above five aspects are all methods to test the performance of potassium ethylenediaminetetraacetate. If the test is up to the standard, the performance is stable and will not interfere with the test. Desheng Biochemical has been committed to developing additives for blood collection vessels. One of the main products is potassium ethylenediaminetetraacetate, which is not only 99% pure, but also has strict requirements in all aspects. Its performance is extremely stable. If you have a demand for potassium ethylenediaminetetraacetate, please click the website to consult and buy!
Latest company new about Who are the manufacturers of EDTA K2 in China, and which ones are of better quality
2022/11/17

Who are the manufacturers of EDTA K2 in China, and which ones are of better quality

EDTA K2, as a blood anticoagulant, is widely used in vacuum blood collection tubes. With the advancement of blood routine projects, the demand for EDTA K2 is also increasing, and the sales of EDTA K2 in the market are gradually optimistic . Many manufacturers of EDTA K2 have emerged as the times require, for example: Qiyue, Baxter, Yuanda and so on. At the same time, it brings products of varying quality. So, which manufacturers of EDTA K2 have better quality in China? Let me introduce it to you in detail.   In fact, one of the Chinese EDTA K2 manufacturers that needs to be introduced here is Desheng Biochemical. Its EDTA K2 has stable performance and good anticoagulation effect, and is well received by customers in China. Why is the quality good?   1. EDTA K2 works well In the process of producing EDTA K2, Desheng will strictly abide by the corresponding process to ensure the use effect. The main content of EDTA K2 produced is as high as 99%, does not contain any impurities, and has stable performance. It can be dissolved in water and has high clarity. Blood anticoagulant, will not react with blood, anticoagulant effect is excellent.   2. After-sales guarantee When anyone buys a product, he will not only consider the quality problem, but also think deeply about the after-sales service after the purchase. Some unreliable EDTA K2 manufacturers will ignore the products after they are sold out. Once there is a problem, they can only hold hands At a loss. And Desheng has professional after-sales service, which increases the guarantee for the purchase of EDTA K2, can also properly solve the problems that arise, and can provide return and exchange services.   3. Sufficient goods In fact, many buyers purchase EDTA K2 in bulk, and the demand is huge. However, many manufacturers cannot provide a large amount of goods for a while, so they have to postpone or not sign the contract. However, Desheng not only has rich experience and core technology, but also has a large number of spot goods in its warehouse, with a daily production capacity of up to tons, which can fully meet the supply of goods and will not be out of stock.   4. Favorable price, trial samples Many customers pay special attention to the price of EDTA K2, which is actually closely related to the quality. If the quality is excellent, the price will naturally be high. However, Desheng’s price is not fixed. It will negotiate the price according to the customer’s demand, and the large quantity can be discounted. Give a satisfactory price. And in order to save customers' time, sample testing will be provided to provide customers with all-round protection.   Desheng Biochemical has always been a professional manufacturer of EDTA K2 in China. It not only sells well in the domestic market, but also has been exporting abroad. The reason why we cooperate with so many customers has a lot to do with its use effect, after-sales guarantee, price and sufficient goods. If you have a demand for EDTA K2, please click the website to inquire for details!  
Latest company new about The Analytical Grade And Industrial Grade Of EDTA Salt Used In Different Fields
2022/11/17

The Analytical Grade And Industrial Grade Of EDTA Salt Used In Different Fields

Ethylenediaminetetraacetic acid is also known as EDTA in Chinese. As an organic compound, it is odorless and tasteless materials, usually can be divided into analytical pure level and industrial level,which can be used in different fields.Among them, EDTA of analytical grade is mostly used in vacuum blood collection tubes, such as dipotassium and tripotassium EDTA. After blood is drawn in the hospital, in order to improve the test efficiency and ensure the test results, anticoagulants will be used to prevent the blood from coagulating.   Because of its ability to complex metal ions, EDTA is close to calcium ions in the blood, chelating them together, and preventing blood coagulation from the root, so it is often added to blood collection tubes for extracorporeal blood anticoagulation. , its anticoagulant effect is good, and it has little effect on the morphology of blood cells.   The requirements for analytically pure EDTA are higher than those for industrial grades, and its purity, performance, melting point, pH value and other key indicators must be strictly required and accurately controlled in analytically pure grades. Although the requirements for industrial grades will be lower, there are also many fields of application, such as applications in water treatment and the preparation of metal polishes.   In terms of water treatment, because EDTA has the characteristics of coordination, it can basically chelate with all metal ions, and this metal chelate has good solubility under slightly acidic conditions, and can be used as water softener and equipment cleaning applications. In the preparation of metal polishing agent, because of its chelating performance with scientifically proportioned, the prepared polishing agent can remove impurities on the metal surface easier.   Desheng Biochemical is a manufacturer of EDTA, which includes dipotassium EDTA, tripotassium EDTA and disodium EDTA.All of them are of analytical grade, with a main content of over 99%. Dipotassium acetate is a dihydrate and is usually used for extracorporeal blood anticoagulation. If you need to use industrial-grade products, you can also go to consult, Desheng can customize according to customer requirements, welcome to click the website or inquire to purchase!
Latest company new about What is the appearance performance of EDTA tripotassium?
2022/11/16

What is the appearance performance of EDTA tripotassium?

What is the appearance performance of EDTA tripotassium?   With the development of medicine, EDTA tri potassium has been widely used in medical institutions in various countries. Many people do not know why it is so hot and popular? In fact, this is mainly related to the performance of EDTA trisotassium. Here is a detailed introduction.   EDTA tri potassium, also known as ethylenediaminetetraacetic acid tri potassium, CAS No. 65501-24-8, is widely added to blood collection tube as an anticoagulant. Its principle of action is that EDTA can be close to calcium ions in the blood, complex with calcium ions, inactivate prothrombin and prevent blood coagulation. The biochemical indicators of blood samples after anticoagulation treatment are closer to the physiological level, which is conducive to the accuracy of detection results and prolonging the storage time of blood samples.   Appearance of EDTA tri potassium   The appearance of EDTA tri potassium is white crystalline powder, no odor, soluble in water, because its powder is easy to absorb moisture from air and water molecules.   Performance of EDTA tripotassium   1. The molecular weight is 442.56, the pH value is 7.3 ± 1 in 5% aqueous solution, the solubility in water is ≥ 60% at 25 ℃, and it is stable at room temperature.   2. The purity is more than 99%, without any impurities. After the powder is dissolved, the water has high clarity, which is easy to add to the blood collection tube without any other adverse effects.   3. EDTA tri potassium does not damage blood cells, does not interfere with the white blood cell count, and prevents platelet aggregation, so it can be applied to general hematological examination. However, it should be noted that due to its anticoagulant effect, it is not applicable to the blood coagulation test. In addition, the ability to complexe calcium ions is also not applicable to the determination of calcium ions, sodium ions, iron ions, etc.   Nowadays, medicine has developed to the era of full automation, and the demand for EDTA tri potassium will become larger and larger. Many businesses in the market have also seized the opportunity and started to sell it on a large scale, which not only leads to the uneven quality of EDTA tri potassium, but also brings pressure to real powerful manufacturers.   Here we recommend a manufacturer of EDTA Tripotassium: "Hubei New Desheng Material Technology Co., Ltd.". This is an old brand manufacturer specializing in the production of additives for blood collection tube. It has not only developed patented products, but also passed the quality certification. At the same time, it can customize products according to customer needs.If you have relevant needs, please click the website for details!
Latest company new about To check the quality of dipotassium ethylenediaminetetraacetic acid, you can look at these indicators
2022/11/16

To check the quality of dipotassium ethylenediaminetetraacetic acid, you can look at these indicators

How can we judge the quality of dipotassium edetate? Many people buy a product now, they have to check what material it is made of and whether its quality is good or not. Not to mention the dipotassium edetate used for blood anticoagulation, its quality requirements are more stringent, and many people will pay special attention to its appearance and key indicators, so let me introduce ethylenediamine in detail below What indicators can be used to check the quality of dipotassium tetraacetate.   1. Purity content The purity of dipotassium EDTA determines whether it contains impurities. The more impurities, the more unfavorable it is for experimental detection. Usually, the purity of dipotassium EDTA is above 99%. If it is lower than 99%, its quality needs to be considered There may be problems. The dipotassium EDTA produced by Desheng is a dihydrate with a purity of 99.5%.   2. PH value The pH value of dipotassium EDTA produced by Desheng is 4.8 ± 1 (5% aqueous solution, g/ml). The pH value plays an important role in stabilizing the performance of dipotassium EDTA. If the pH value is Alterations in selection and control have a direct impact on test results.   3. Compatibility of Dipotassium EDTA with other blood collection tube additives Different blood collection tubes have different testing items, and their requirements are also different, and this requires that dipotassium edetate can work well with other additives in blood collection tubes, such as being placed together with serum separating gel In the nucleic acid detection test tube, it is required that the two cannot react, remain stable, and play their respective roles.   4. Solubility The solubility of dipotassium edetate is a key indicator. Since the appearance of the produced product is mostly white crystalline powder, it exists in the form of water mist when placed in blood collection tubes. If its solubility is not good , or the dissolution is very slow, which will inevitably affect the entire detection process. The dipotassium produced by Desheng is dissolved in 100 ml of pure water at room temperature (25±5°C), stirred for 5-10 minutes, and then dissolved.   5. Storage time of dipotassium ethylenediaminetetraacetic acid The validity period of dipotassium ethylenediaminetetraacetic acid is generally determined according to the manufacturer. The indicators of each manufacturer are different, and its shelf life is 1 year, 2 years or 3 years. The ability to guarantee the original properties of the blood sample shows that the performance and quality of dipotassium is relatively good.   Desheng Biochemical has been committed to the development of blood collection tube additives for many years. Now the series of products produced include serum separation gel, heparin sodium, heparin lithium, EDTA dipotassium, tripotassium, disodium, etc., and customers have repurchased them for a long time, proving its The product quality is excellent, and the key indicators are up to standard, even more accurate. If you have a demand for dipotassium edetate, please click the website for consultation!  
Latest company new about Are plastic tubes, glass tubes all suitable for  EDTA K2 anticoagulant?
2022/11/16

Are plastic tubes, glass tubes all suitable for EDTA K2 anticoagulant?

Are plastic tubes, glass tubes all suitable for EDTA K2 anticoagulant?   In recent years, the series of vacuum blood collection tubes used for blood samples have become mainstream. In the past, after blood samples were drawn, waiting for blood coagulation, blood centrifugation, and measuring storage time not only affected the analysis results, but also lengthened the entire time period. In order to improve efficiency, it was later developed to add anticoagulant or coagulant, serum separation gel, etc. to blood collection tubes. The more commonly used is EDTA anticoagulant, which greatly facilitates clinical blood testing.   At the same time, in order to prevent cross-infection safety hazards, standardize the testing of blood collection technology, and then there will be a complete set of whole blood collection tubes, including plastic tubes and glass tubes. The vacuum test tube added to EDTA K2 anticoagulant can be either a plastic tube or a glass tube. The overall performance of EDTA K2 anticoagulant has no fundamental connection with the test tube, but these two tubes have their own advantages and disadvantages. Let me introduce to you the difference between EDTA plastic tubes and glass tubes.   1. Glass tube After blood collection, the inner wall of the glass test tube will often absorb water molecules. As the blood sample is placed, the potassium or enzyme substances in blood cells will diffuse into the serum through water molecules. Complete the blood test as soon as possible within hours, and the use of glass test tubes will further shorten the blood storage time, and the glass tubes are easy to break, which is extremely inconvenient for transportation.   2. Plastic tube Although the plastic tube is easy to transport and not easy to break, its water retention is not good, and it is easy to cause the sprayed EDTA K2 solvent to evaporate within a certain period of time. However, PET plastic vacuum blood collection tubes are more special. Under low temperature conditions, such as Specimens can also be preserved at -20°C, which is difficult for ordinary plastic and glass test tubes. Nowadays, some fast-growing blood collection tube companies have produced double-layer plastic tubes. This kind of test tube not only does not evaporate the solution, but also solves the transportation problem. Of course, its production cost is relatively high.   Desheng Biochemical specializes in providing all kinds of blood collection tube additives. We have a complete range and high-quality products that has been repurchased by customers for a long time and sold overseas. We have signed supply contracts with more than 100 companies. We are equipped with a large warehouse and a daily production capacity of up to tons, which can solve the troubles of customers out of stock and out of stock. If you have needs for blood collection tube additives, please visit our website!  
Latest company new about How Is EDTA K2 Configured Solvent To Be Used In A Purple Cap Tube?
2022/11/15

How Is EDTA K2 Configured Solvent To Be Used In A Purple Cap Tube?

EDTA K2 is a kind of crystal obtained by the reaction of EDTA and potassium hydroxide. After dehydration, drying, grinding, and pulverization, the powder can be obtained. When using, the powder needs to be prepared into solvent and sprayed on the inner wall of the blood collection tube as anticoagulants.   Among the test tubes with caps of different colors, the purple test tube is an anticoagulant tube with EDTA K2 added. The EDTA in it has a chelating force for calcium ions in the blood, which can prevent the coagulation process, prevent the blood sample from coagulating, and also prevent platelet aggregation phenomenon.   The EDTA K2 produced by Desheng is in powder form. It needs to be configured as a solution and added to the purple cap tube before use. The configuration of EDTA K2 is not as difficult as imagined. The following summarizes several configuration steps for reference.   Determine the dosage According to the experimental data of the reference document, the content of EDTA K2 in each millimeter of blood is 1.5-2.2 mg, so when adding the amount of EDTA K2, it is necessary to consider the amount of blood collected in the test tube, so that there will be no waste when configuring nor lead to errors in the test results.   Configuration steps First,weigh the required amount of EDTA-K2 powder with an electronic balance.   Second,pour a part of the powder into deionized water or distilled water to dissolve it. During this period, it needs to be stirred continuously, and then slowly pour the remaining EDTA-K2 powder in the continuous stirring.   Third. After observing that the powder is completely dissolved, add deionized water or distilled water again, and make up to the required amount.   Fourth. Pour the constant volume solution into an airtight container, slowly and repeatedly invert and mix six or seven times. The prepared solution can be stored at -4°C for a maximum of one week, so it is best to prepare before using.   Fifth,add the prepared solution into the test tube, slowly turn and tap the test tube to make it fully touch the inner wall of the test tube, and then dry it.   However, it is necessary to pay special attention to the fact that when preparing the solution, it is necessary to confirm the required concentration. Sometimes the concentration is too high, which will lead to the increase of local osmotic pressure and the destruction of blood components, resulting in hemolysis.   As a manufacturer of blood collection tube additives, Desheng Biochemical has been committed to becoming the world's leading brand. At present, the purity of EDTA produced is as high as 99.5% and its performance is stable. It has provided goods for many companies with  deeply trusted by customers. If you have blood collection tube additives in terms of needs, please click on the website for consultation!
Latest company new about What are the Usage and Precautions of ACD Solution in PRP Tube?
2022/11/14

What are the Usage and Precautions of ACD Solution in PRP Tube?

In recent years, blood protection has become an important research hotspot. How to store the collected blood for a long time and how to reduce the infection during the blood collection process are all essential hot topics. The most important thing is to protect the red blood cells in the blood.   After the continuous development of medicine, vacuum blood collection tubes and various additives suitable for adding into test tubes have been developed, such as heparin series anticoagulants, EDTA and ACD solutions, which are not only convenient and fast, but also greatly improve the safety and accuracy.Next, I will introduce the ACD solution in the PRP tube in detail.   Composition and working principle of ACD solution In fact, ACD solution is mainly composed of citric acid, sodium citrate and glucose. It is an anticoagulant commonly used in blood collection and blood storage. Because the main component citrate ion and Ca2+ form a complex that is difficult to dissociate, but soluble in water. It blocks the activation of factor X in the coagulation pathway, inhibits the formation of coagulation factors, thrombin and fibrin, and inactive the thrombin to prevent the blood coagulant.   Advantages of ACD Solutions The advantage of ACD solution is that the collected blood sample is fully anticoagulated inside the test tube, and it is not used directly in the body. And from the perspective of ingredients, citric acid and sodium citrate can form a buffer pair, which can relieve and adjust the pH value of the solution, and glucose can provide an energy source, which is conducive to the preservation of red blood cells.   Amount of ACD solution should be used For blood bank storage, 0.025 liter of ACD solution can be added to every 0.1 liter of blood, and it can be stored for about 3 weeks,but not longer than 28 days. 14ml of blood preservation solution was added to every 100ml of whole blood.   Precautions for ACD Solutions It is not advisable to input excessive ACD solution or add it too fast, because if the sodium citrate in the component is input too much and there is no time for oxidation, it will complex with the free calcium ions in the plasma to generate sodium calcium citrate that is difficult to dissociate. Hypocalcemic convulsions occur when banked blood is transfused into humans. In addition, the transfusion of banked blood into newborn infants will also cause hypocalcemia due to underdevelopment of the enzyme system during blood transfusion. It should be noted that 10% calcium gluconate should be injected intravenously during the transfusion of 1000 ml of blood.   Desheng Biochemical is a professional manufacturer of blood collection tube additives. It has been established for more than 10 years. Various additive products, such as serum separation gel, sodium heparin, lithium heparin, sodium citrate, EDTA have been exported to various countries with affirmation of the majority of customer groups. If you have needs for blood collection tube additives, you can click the official website to consult!
Latest company new about The Scope of Use of Dipotassium ethylenediaminetetraacetate EDTA K2
2022/11/10

The Scope of Use of Dipotassium ethylenediaminetetraacetate EDTA K2

Dipotassium ethylenediaminetetraacetate, also known as EDTA K2, is a white crystalline powder on the surface. It is a common complexing agent because it can complex with calcium in the blood to inactivate calcium, thereby preventing blood with coagulation purpose.It is often used in the preparation of anticoagulants in vacuum blood collection tubes.   There are two CAS numbers of dipotassium EDTA, one of which is dipotassium EDTA crystal hydrate, the CAS number is 25102-12-9, and the CAS number of dipotassium EDTA is 2001-94-7, many people will confuse these two CAS numbers. You need to pay special attention to the difference is that one molecule differs by two crystal waters. Desheng will give a general introduction to the scope of use of Dipotassium EDTA.   1. Used in vacuum blood collection tubes In recent years, with the upgrading of blood testing, Dipotassium EDTA has been widely used in blood collection tubes. As an anticoagulant, it can rapidly store leukocyte hyperplasia for a period of time, prevent platelet aggregation, and prevent blood from coagulating , which not only facilitates medical staff to improve blood testing efficiency, but also promotes more accurate test results.   2. Used in industrial production In addition to the common use for blood anticoagulation, dipotassium EDTA can also be used in the field of industrial production and can be used as a buffer. When used in gel engineering, it not only has excellent retardation effect, but also can prolong the time of the repair system and ensure a certain strength, so that it can be quickly repaired on bridge decks, highways, etc.   3. Used in oilfield production In oilfield production, dipotassium EDTA can be used as a stabilizer, which can not only chelate calcium and magnesium ions to stabilize the entire operating system, but also constitute a desulfurization synergist, so that the desulfurization synergist can effectively interact with the sulfide in the system. A chemical reaction is generated to effectively remove sulfides and ensure production safety.   4. Used in daily chemicals Dipotassium EDTA can also be used in deodorants or detergents, liquid soaps, and has a significant effect on deodorizing at home. In addition, according to research, dipotassium EDTA can also be used to prepare activated carbon.   Desheng Biochemical is the source manufacturer specializing in the production of dipotassium ethylenediaminetetraacetate. The series of products produced are stable in performance, and the quality is supervised and controlled by professionals. The products produced in the same batch will be tested first before delivery. If you have a demand for blood collection tube additives, please click on the website for inquiry!
Latest company new about What is the anticoagulation principle of Dipotassium EDTA in VBCTs?
2022/11/09

What is the anticoagulation principle of Dipotassium EDTA in VBCTs?

When many people go to the hospital to check their health, they will find blood routine must be tested.Most medical staff will judge whether the patient has a hidden disease or aggravated disease based on the analysis of the patient's blood sample. As a blood anticoagulant, Dipotassium EDTA is often added to VBCTs. It has the advantages of good anticoagulation effect and less influence on the morphology of blood cells. Next, I will introduce you anticoagulation principle of potassium in vacuum blood collection tubes.   In fact, if you want to understand the anticoagulation principle of dipotassium EDTA, you need to know 4 steps of blood coagulates. 1. The production of prothrombin activator. 2. The next step is that prothrombin becomes active under the influence of calcium ions and phospholipid membranes. 3. Under the above two steps, fibrin is formed. Due to the participation of thrombin, soluble fibrinogen is converted into insoluble fibrin. 4. After the formation of fibrin, thrombin will be adsorbed, and local blood clots will form.   These four steps are roughly the process of blood coagulation.Dipotassium EDTA,a white crystalline powder is used as a complexing agent. Since dipotassium EDTA is close to calcium ions, it can complex and block the formation of thrombin from prothrombin, that is, the second step of the above blood coagulation process is suspended, which prevents blood coagulation from the source, and subsequent coagulation process cannot continue.   Due to its anticoagulant advantages, Dipotassium EDTA is regarded as an ideal anticoagulant in routine blood analysis, but some issues need to be paid attention to when using it, such as the ratio of blood to Dipotassium EDTA. Disproportion can cause a slight clotting phenomenon, which can block the blood analyzer or cause inaccurate test results. In addition, in order to ensure sufficient anticoagulation effect, after blood collection, medical staff should mix upside down 5-8 times to ensure that the blood is completely exposed to the anticoagulant to avoid partial coagulation.   Hubei New Desheng has been developing and producing blood collection tube reagents since its establishment. It is a relatively old-fashioned manufacturer. The unit packaging volume of its Dipotassium EDTA anticoagulant is 500g/bottle and 25kg/barrel.Price based on the quantities. So far, the products are sold at home and abroad, the repurchase rate is high. If you have this demand, please click on the website to consult the details!
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