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Biological Good Buffer Solutions BICINE CAS 150-25-4 White Crystaline Powder 99%

Product Details

Place of Origin: EZHOU, CHINA

Brand Name: DESHENG

Certification: ISO9001:2008

Model Number: BICINE

Payment & Shipping Terms

Minimum Order Quantity: 500g

Price: Negotiable

Packaging Details: Plastic bottle/Ctn Box

Delivery Time: 3-5 working days

Payment Terms: L/C, D/A, D/P, T/T, Western Union, MoneyGram

Supply Ability: 10000kg/Month

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Specifications
High Light:

BICINE Good Buffer Solutions

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150-25-4 Good Buffer Solutions

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CAS 150-25-4 BICINE

Name:
BICINE
Full Name:
N-bis(hydroxyethyl)glycine
CAS #:
150-25-4
Molecular Weight:
163.17
Molecular Formula:
C6H13NO4
Category:
Good's Buffer
Field:
Biological Buffer
Function:
PH Aujustment
Apprearance:
White Crystal Powder
Purity:
>99%
Industry:
Medical & Health
Name:
BICINE
Full Name:
N-bis(hydroxyethyl)glycine
CAS #:
150-25-4
Molecular Weight:
163.17
Molecular Formula:
C6H13NO4
Category:
Good's Buffer
Field:
Biological Buffer
Function:
PH Aujustment
Apprearance:
White Crystal Powder
Purity:
>99%
Industry:
Medical & Health
Description
Biological Good Buffer Solutions BICINE CAS 150-25-4 White Crystaline Powder 99%

Good Buffer Solutions Biological buffer BICINE CAS150-25-4 white crystaline powder Purity>99%

 

 

Bicine is an amino acid derivative, weakly acidic, pH buffer range is 7.6-9.0, soluble in water and commonly used organic solvents such as DMF, DMSO, DMAc, etc.When powdered bicine is formulated into a solution, sodium hydroxide is usually added to adjust the pH value to meet the pH environmental requirements required for the experiment or detection.If the experimental environment needs to exclude the interference of sodium ions, potassium hydroxide can be used instead of sodium hydroxide, and then the pH is measured by a pH meter to adjust the mixing ratio of Bicine solution and alkali solution.
 
Similar to the working principle of other biological buffers, Bicine plays a buffering role when acid and base are added into the reaction system or when the pH of the reaction environment changes as the reaction proceeds. It maintains the pH value of the reaction system, which is intuitively important when enzymes or proteins and accounting are involved in the biochemical detection. Most organic biomolecules are stable.And functionality is very sensitive to pH.
 
Performance and Advantages of Biological Buffer Bicine White Powder with Purity 0
Bicine reagent
 
The molecular structure of Bicne is similar to that of glycine. The hydrogen on the amino nitrogen atom is replaced by two hydroxyethyl groups, which reduces the hydrolysis ability of the amino terminal and enhances its stability. At the same time, Bicne has the properties of amino acid and aminoethanol and can be used as a monoanion.
 
(Bic-) forms metal complexes.The buffer system prepared with Bicine and sodium hydroxide will not participate in the chemical reaction of the reaction system, and will not interfere with the experimental reaction. It is resistant to chemical action and enzymatic hydrolysis.

 

 

Product Name

N, N-dihydroxyethylglycine

 

Basic Information

Abbreviation BICINE Molecular weight 163.17
CAS No 150-25-4 Molecular formula C6H13NO4
Appearance White crystal powder Purity ≥99%
Storage Conditions Room temperature, light-proof and moisture-proof

 

Description

Bicine is one of the commonly used biological buffers. It is an amphoteric amino acid buffer and has activity in the pH range of 7.6-9.0 (pKa of 8.3 at 25 ° C). Recommended buffer for low temperature biochemical work. Bicaine is used to prepare a stable serum guanosidase substrate solution. A method for protein separation using dihydropyridine in thin layer ion exchange chromatography has been published. Dihydropyridine has been used for peptide and protein crystallization.

Biological Good Buffer Solutions BICINE CAS 150-25-4 White Crystaline Powder 99% 1

 

Applications of N, N-dihydroxyethylglycine (Bicine)

1. The molecular structure of Bicine is similar to glycine. The molecule has a substituted amino group, a carboxyl group and 2 hydroxyl groups as coordination groups, so it has the properties of both amino acid and aminoethanol, and can form a metal with a single anion (Bic-) The complex is often used as a buffer solution for capillary electrophoresis.

 

2. According to the description of patent CN104245089A, Bicine is suitable as an effective inhibitor of oxidative degradation of amines, and can effectively inhibit the oxidative degradation of amines used or amine-containing absorbents used.

 

3.Used to prepare a stable substrate solution for serum guanine enzyme determination. It is also a very widely used Buffer, used in enzyme reaction buffer, electrophoresis buffer, working concentration from 3-100mM.

 

4.Bicine is an amino acid analog that is easily soluble in water. It is an environmentally friendly substance. The molecule contains two -OH and one -COOH. It has good chelating properties and can chelate heavy metal ions such as Cu, Cd, and Pb. , but can not chelate calcium and magnesium ions. Therefore, Bicine is often used as a chelating agent to repair heavy metal contaminated soil. Bicine has a good elution capacity for heavy metals under neutral and acidic conditions, and can efficiently remove Cu, Cd, and Pb ions in contaminated soil. Bicine is the eluent of the active component, which can not only rinse and repair heavy metal contaminated soil, but also avoid the loss of plant nutrient elements calcium and magnesium in the soil. It is safe and environmentally friendly, and will not cause secondary pollution to the environment.

 

Biological Good Buffer Solutions BICINE CAS 150-25-4 White Crystaline Powder 99% 2

Advantage

The purity (> 99%) is water-soluble and the process is stable.

 

1. Bicine is often used as a buffer solution for capillary electrophoresis
Bicine is a zwitterionic buffer, belonging to Good’s buffer, with a pH buffer range of 7.6-9.0. The molecular structure of Bicine is similar to that of glycine. The molecule has a substituted amino group, a carboxyl group and two hydroxyl groups as coordinating groups, so it has the properties of amino acid and aminoethanol at the same time. It can form metal complexes with a single anion and is often used. Used as a buffer solution for capillary electrophoresis.
2. Bicine is an effective inhibitor for the oxidative degradation of amines
According to the description of patent CN104245089A, Bicine is an effective inhibitor for the oxidative degradation of amines, and can effectively inhibit the oxidative degradation of the amine used or the amine-containing absorbent used.
3. Bicine is used as a chelating agent for soil remediation
Bicine is an amino acid analogue that is easily soluble in water. It is an environmentally friendly substance. It contains two -OH and one -COOH in the molecule. It has good chelating properties and can chelate heavy metal ions such as Cu, Cd, and Pb. Can not chelate calcium and magnesium ions. Therefore, Bicine is often used as a chelating agent to repair heavy metal contaminated soil. Bicine has good elution ability for heavy metals under neutral and acidic conditions, and can efficiently remove Cu, Cd, Pb ions in contaminated soil. Bicine is the eluent of active components, which can not only wash and repair heavy metals It pollutes the soil, and can avoid the loss of plant nutrients calcium and magnesium in the soil, is safe and environmentally friendly, and will not cause secondary pollution to the environment.
Bicine is also a widely used in vitro diagnostic reagent raw material, suitable for biochemistry and medicine. In the field of in vitro diagnostics, it is an important raw material for antibody detection reagents and nucleic acid detection reagents.

Biological Good Buffer Solutions BICINE CAS 150-25-4 White Crystaline Powder 99% 3

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