China Wuhan Desheng Biochemical Technology Co., Ltd Company News

N-Tris(Hydroxymethyl)Methyl-3-Aminopropanesulfonic Acid (TAPS) is a white powder with molecular formula c7h17no6s, molecular weight 243.278, CAS number 29915-38-6, and TAPS buffer is also called tabs Buffer, a sulfonic zwitterionic buffer, is widely used in biochemistry and molecular biology. Its pH buffer range is 7.7-9.1, soluble in water (25g / 50ml) and PKA is 8.4. It is commonly used in biochemical diagnostic kit, DNA / RNA extraction kit and PCR diagnostic kit in clinical diagnosis. In biological and biochemical experiments, it is often necessary to use the medium with stable pH range, so buffer reagent is often used. The traditional buffer composed of weak acid and its salt or the mixture of weak base and its salt has many kinds, low price and easy to obtain, but it has some shortcomings, such as insufficient buffer capacity, affecting the biochemical reaction process and so on.   Sulfonic acid type biological buffer is an ideal biochemical buffer at present, which has many outstanding characteristics superior to the traditional buffer. Taps sulfonic biological buffer is often used as a buffer system in DNA screening system, and can also be used as a buffer component of RNA samples; it is suitable for electron transfer and phosphorylation research of chloroplast thin layer preparation; it can protect oxyhemoglobin from oxidation to methemoglobin during freeze-drying; it can also be used as a background electrolyte for protein microanalysis by capillary zone electrophoresis.   Desheng biochemical, as an old manufacturer of in vitro diagnostic reagents, produces taps buffers with high purity, good quality, stable buffering performance and little impact on the experimental results. In addition to taps, we can also provide other biological buffers such as Tris, HEPES, caps, mops, as well as various in vitro diagnostic reagent raw materials such as chemiluminescence reagent, chromogen substrate, blood collection vessel additive, etc.   Desheng biochemical friendly tips:   1. Protection should be done according to the situation of the test. Wear necessary protective tools, test clothes, rubber gloves, protective mask, gas mask, etc. according to the possible dangerous accidents. Before the experiment, we should pay attention to clean up the potential safety hazards around the test site. Check whether the test device, drugs and related articles do not meet the requirements.   2. Follow the nature of chemicals and the law of chemical reaction to avoid the experimental accidents caused by improper operation. The matching reaction device should be selected according to the nature and process of chemical reaction, and the necessary safety measures should not be omitted.   3. To estimate the risk of the experiment, attention should be paid to the following types of experiments: ① unknown reactions and operations; ② experiments with multiple risks (such as fire, toxic and harmful gases, etc.); ③ experiments under harsh reaction conditions (such as high temperature, high pressure, etc.).   4. Take accident prevention measures and check: be familiar with the position and operation method of switches and fire extinguishers around the experimental environment.   5. Post treatment: pay attention to the cleaning of the experimental platform, the arrangement of articles, the treatment of waste liquid, etc.

Biological buffer is a kind of solution that can keep the pH value of the solution relatively stable when a small amount of acid or alkali is added. Most cells can only carry out activities in a very narrow pH range, and need a buffer system to resist the pH changes in the process of metabolism. In biochemical research, buffer solution is often used to maintain the pH of the experimental system. Let's take a look at the commonly used biological buffer solutions and their characteristics.   Desheng buffer packaging   Phosphate buffer   Phosphate buffer is the most widely used buffer. Due to the secondary dissociation, the pH range of the buffer is wide, and the acidic, alkaline and neutral buffers with different pH values can be configured   When preparing acidic buffer solution, NaH2PO4 or KH2PO4 can be used directly, and the pH value ranges from 1 to 5; Alkaline buffer can be directly used Na2HPO4 or K2HPO4 with pH range of 9-12; The neutral buffer contains the same amount of NaH2PO4 and Na2HPO4 or the same amount of KH2PO4 and K2HPO4 solution, and the pH value is 5.5 ~ 8.5.   Advantages: ① easy to prepare into various concentrations; ② wide range of pH value; ③ little influence of temperature on pH value; Disadvantages: ① it is easy to precipitate with common calcium, magnesium and heavy metal ions; ② it inhibits some biochemical processes; Desheng Laboratory Tris buffer Tris buffer is widely used in biochemical research. It is a weak base and is usually used in the "neutral" range. In addition to tris - HCl, Tris has a variety of derivatization buffers   TBS = Tris HCl + NaCl + KCl, which is often used to clean the Western blotting membrane of immunostained tissue or Western blotting; Tbst = Tris HCl + NaCl + Tween20, a membrane buffer commonly used for Western blotting; TE = Tris HCl + EDTA, which has protective effect on DNA base and is often used for DNA stabilization and storage; Tae = Tris base + acetic acid + EDTA is a buffer system widely used in short DNA electrophoresis; Tbe = tribasic + boric acid + EDTA, suitable for long-term DNA electrophoresis, with good separation effect for small fragments   Advantages: ① because Tris base has strong alkalinity, it can only be used to prepare buffer solution with a wide range of pH from acidic to alkaline; ② it has little interference to biochemical process and does not precipitate with calcium, magnesium ions and heavy metal ions. Disadvantages: ① the pH value of the buffer solution is greatly affected by the concentration of the solution, and the pH value changes more than 0.1 when the buffer solution is diluted ten times; ② the temperature effect is large, and the temperature change has a great influence on the pH value of the buffer solution, so it must be prepared at the use temperature, and the tris HCl buffer prepared at room temperature cannot be used at 0 ℃ ~ 4 ℃. (3) it is easy to absorb CO2 in the air, so the prepared buffer should be tightly sealed. ④ The buffer solution interferes with some pH electrodes, so the electrode compatible with tris solution should be used.   Glycine buffer   Glycine buffer has a wide range of pH value and wide range of application, ranging from 2.0 to 11.0.   Advantages: provide a closer natural environment for cell components and various extracts. Disadvantages: similar to phosphate buffer system; interferes with some biochemical processes, such as metabolism.   Desheng technology was founded in 2005. After years of innovation and development, the company has become a national high-tech enterprise with R & D, production, sales and service as a whole, which is dominated by in vitro diagnostic reagent raw materials, biological buffer, blood collection additive, color reagent and chemiluminescence reagent.

The full name of toos is n-ethyl-n - (2-hydroxy-3-sulfopropyl) - 3-methylaniline sodium salt, which is a widely used in vitro diagnostic reagent and is most commonly used in the new Trinder's reagent. Tools has been used in many clinical biochemical tests. Which tests can tools be used in?   Toos is widely used in diagnostic detection and biochemical test by Trinder reaction. Trinder reaction is also known as "coupling end-point colorimetry". The principle is that hydrogen peroxide (H2O2) produced by enzymatic reaction of the tested substance can generate red quinoline compound in the presence of 4-aminoantipyrine (4-AAP) and peroxidase (POD). Blood glucose test items: toos is used to prepare glucose test reagent and glycosylated albumin test reagent in blood glucose metabolism items.   Glucose oxidase was used to catalyze the oxidation of glucose to produce hydrogen peroxide. Platinum bismuth nanomimetic peroxidase was used to catalyze the oxidation of 3-methyl-2-benzothiazolinone hydrazone hydrochloride (MBTH) and sodium n-ethyl-n - (2-hydroxy-3-sulfopropyl) - 3-methylaniline (toos) by hydrogen peroxide. The color of the solution was purple. With the increase of glucose concentration, the color of the solution increased, The maximum absorption wavelength of the chromogenic system is 590 nm, and the content of glucose can be obtained from the absorbance at 590 nm.   Routine examination items of liver function: adenosine deaminase (ADA) activity is a sensitive index reflecting liver injury, and it is one of routine examination items of liver function. TOOS, bovine serum albumin, disodium ethylenediamine tetraacetate and other components of adenosine deaminase detection reagent have the advantages of good color effect, rapid response, stability and high precision.   In addition, tools is also used in triglyceride and other blood lipid testing items and cholesterol testing items of diagnostic reagents, which has important value in clinical diagnosis.   "Toos" here refers to the in vitro diagnostic reagent toos. Hubei xindesheng Material Technology Co., Ltd. is a manufacturer of in vitro diagnostic reagent raw materials. In addition to providing toos, it can also provide many chromogen substrates, such as heparin lithium, heparin sodium, EDTA dipotassium / Tripotassium, and biological buffers such as Tris, Tris-HCl, HEPES, mops, etc.

Nowadays, more and more in vitro diagnostic reagents come into family life, such as early pregnancy test and blood glucose monitoring. This kind of application brings many differences in understanding and problems in use. There is a great demand for popularization of knowledge in the aspects of product safety, storage, inspection and its use. Popularization of science is becoming more and more necessary. Today, Desheng edited some popular science knowledge, which will be displayed in the form of question and answer for everyone to learn. What are the main aspects of the safety of in vitro diagnostic reagents?   A: in vitro diagnostic reagents are used to diagnose whether patients or examinees contain certain infectious factors or whether certain functions of the body are normal, so the reagents themselves need to be safe and non infectious. In order to protect personnel from infection of positive substances when using in vitro diagnostic reagents, all materials containing infectious factors should be inactivated before use. In order to protect the operators from damage, the containers of each component of the kit should avoid using glass materials, plastic products should be used as far as possible, and metal aluminum covers should be avoided, instead of plastic materials. In the chemical reagent components, avoid the use of strong acid, strong base reagents. What are the main forms of test results of in vitro diagnostic reagents? A: at present, in vitro diagnostic reagents are used for testing, and the results are mainly reported in three forms: One is qualitative test: the result is either "negative" or "positive". For example, if the test shows that HBsAg is positive, it means that there is hepatitis B virus in the patient's body. Second, semi quantitative detection: it is mainly used to detect the titer, which is often used for antibody determination, such as antinuclear antibody 1:16, etc., which is a semi quantitative report form. The third is quantitative detection: using specific numerical report (which is also the most frequent way on the inspection report at present). When you look at the report sheet that uses numerical value to report the test results, you must pay attention to the unit of measurement behind the item. Different units of measurement result in different data, sometimes thousands of times different. However, it should be noted that when judging the change trend of the test results of a certain index, we should not only look at the numbers, but also pay attention to the units. Only when the measurement units are the same, the results can be comparable. 3. What is the intended use of in vitro diagnostic reagents? A: the intended use of in vitro diagnostic reagent products is generally approved by the food and drug administration, which is scientific and legal, such as "auxiliary diagnosis" and "diagnosis", "early diagnosis", "screening", "treatment monitoring", "individualized drug use" (accompanying diagnosis), etc. at the same time, quantitative or qualitative detection and sample type should be marked on the instruction manual What are the requirements. I hope the popular science knowledge organized by Xiaobian today can help you learn better. Desheng is a professional manufacturer of in vitro diagnostic reagents. Its main products include chemiluminescent reagents, blood collection additives, biological buffers, chromogenic substrates, enzyme preparations, etc.

A sudden outbreak makes the Carbomer, the important raw material of the hand sanitizer gel, become the "Darling" of the market at once. Besides, its important applications in transparent skin gel, hair gel, shampoo, bath and so on are also making more and more manufacturers look at the bonus market. As more and more companies join the production of carbomer industry, It is bound to make buyers dazzled. How to choose high-quality cabom suppliers is a very important issue. Desheng tells you several problems that should be paid attention to in purchasing.   Carbomer powder and gel   1. Is the price really favorable for large quantity   Desheng is really taking action when many cabom suppliers are trying to attract customers with a large amount of advertising words with better price. Desheng now launches cabom 940 and cabom 980, which are in sufficient stock and can enjoy the price of 100 yuan / kg for tons and above. Many customers can't believe it when they see these words. Desheng hereby declares that this activity is really successful It's really effective. The deadline of the event is November 26, 2020. If you miss this wave of discount, you won't know when you can enjoy it next time.   2. Whether there is enough stock and whether the delivery is timely   Many customers consult more than tons. If there is not enough stock as support, on the one hand, many important customers will be lost, because it is difficult to have the willingness to continue the negotiation. On the other hand, under the condition of insufficient goods, once a customer orders, the delivery cycle is long, if an order takes a long time to reach the customer's hand, the customer's demand will be reduced The feeling of purchasing experience is very bad. After upgrading and transforming the equipment, Desheng can achieve the monthly output of tons, and the delivery is very timely, so there is no need to worry about this.   3. Is it possible to provide trial equipment   The manufacturers who can provide trial products come from their high trust in their own quality. There is only one reason why they can't provide trial products of carbomer. They are afraid that they will never come back after the trial. The real carbomer manufacturers believe that only if the product quality is good, they can confidently tell you that if you have doubts about the product quality, you can try them first. If the trial is good, they will come to you If you order a large number of products, if there is a problem with the quality of the products themselves, who will lift a stone to hit their own feet? Therefore, it is also a very critical point whether you can provide trial equipment. Desheng can provide trial equipment. Only after the trial can we know whether the products are good or not. Desheng believes that good wine is not afraid of deep alleys, and good products are not afraid of trial.   Desheng company is now launching carbomer 940 and carbomer 980, with sufficient stock. The price of carbomer 940 and carbomer 980 is reduced to the ton price of 130 yuan / kg in order to expand the market. The price reduction does not reduce the quality. The carbomer powder produced by Desheng is obviously white, and the powder is more fluffy and delicate. In the configuration of solvent, the transparency is also much higher than that of similar products. Because Desheng is a direct manufacturer, so for individual indicators can also be customized, welcome to buy!

In recent days, the weather in many parts of the south is still relatively good, but suddenly a north wind blows, and the temperature drops. Yesterday it was nearly 30 degrees, today it is only more than 10 degrees. As the temperature drops, I hear the feedback from customers. When the weather gets cold, it's always difficult to add glue every time.   In view of this problem, as a manufacturer of vascular additive, we have also carried out various experiments, so what is the problem?   The results showed that: 1. Serum separation gel is still a glue body with viscosity, and the viscosity has a certain relationship with temperature. When the temperature is too low and the weather is cold, the viscosity of separation gel increases, and the process of adding glue is difficult.     2. Serum separation gel is a mixture, but the uneven distribution of individual molecules will also lead to the phenomenon of jam and difficulty in the process of adding gel.   3. In winter, the glue is heated. The separating glue can withstand the high temperature below 80 ℃. Now many equipment production company glue machine with heating function, for blood collection enterprise provides a solution. In addition, part of the problems can be solved by reducing the viscosity of the separating gum.   Generally speaking, it is difficult to add the separating glue, and the temperature has a lot to do with it. If you know the reason why it is difficult to add the serum separation gel, you can start to solve it one by one. Of course, there must be a premise, a sound R & D team, which can constantly adjust the difficulty of adding the serum separation gel due to the change of temperature, and then continue to experiment to achieve a good balance. As a manufacturer, Desheng has a professional research team and the determination to solve problems.

If you ask what can quickly open up the topic of beauty, it's certainly cosmetics and skin care products. Not only have they become indispensable for women's skin control, but even men have to "grab a share". The demand for skin care and make-up is becoming more and more common. Many people may not know that there is a very important raw material in their skin care products - carbomer Is one of the indispensable ingredients, so why does carbomer's position in the cosmetics industry remain high? The following five reasons are for reference only.   1. Carbomer has good transparency in cosmetics. Don't underestimate the problem of transparency. The transparency produced by different manufacturers is different. Carbomer products with high transparency are more popular in the market. It can be imagined that if the cosmetics made from carbomer raw materials do not have a good transparency, there will be no good concept The final product will make customers have no desire to buy. The carbomer 940 produced and developed by Desheng has high transparency and viscosity, which can meet the needs of most buyers.   2. carbomer does not support bacterial mold growth. Bacterial mold growth does not affect gel properties. The conventional dosage is 0.2-0.4%, which can replace 3-7% of conventional emulsifier. Carbomer polymer hardly has the property of surfactant, so adding 0.1-0.5% low HLB surfactant can adjust the oil phase particles to be smaller, so as to prepare white and delicate cream products.   3. carbomer is a macromolecule polymer, thickener, gel and emulsifying stabilizer. Carbomer has good compatibility with pH, and can be used in both acidic, neutral and alkaline conditions. As we all know, pH value of skin care products is a very important factor. Different skin types are suitable for skin care products with different pH values. Carbomer as a good gel matrix can be applied to skin care products with different PH values, so that more skin care products with high skin value suitable for different skin types can be made possible.   4. carbomer in cosmetics, skin care products, the main role is thickening agent, emulsifying stabilizer, gel, the risk coefficient is 1, relatively safe, can be used at ease, for pregnant women generally have no effect, Carbomer is not carcinogenic.   5. at a very low dosage (regular dosage of 0.25-0.5%), it can produce an effective thickening effect, thus preparing a wide viscosity range and rheological properties of emulsion, cream, gel and transdermal preparation. This is also a very important factor. If a product needs a high amount of material to achieve the corresponding thickening effect, it will undoubtedly increase the procurement cost of a product.   Desheng is a professional carbomer manufacturer. Carbomer 940 is very suitable for all kinds of cosmetics. It should be noted that when the skin care products are applied, Carbomer's final concentration is controlled less than 0.8%. It is suggested that it is suitable for about 0.5%. When the concentration is more than 0.8%, it is easy to form a film. Add as appropriate, the company can provide professional and technical guidance, welcome to call the detailed consultation.

In vitro diagnosis is the cornerstone of modern medical diagnosis, treatment, prevention, prognosis and other clinical decision-making, which can be called "medical scout". At present, the contribution of in vitro diagnosis to clinical medical decision-making has exceeded 70%. From a certain point of view, the 21st century is the century of biotechnology, in vitro diagnosis industry has become one of the most active and fastest growing industries in the world.   Although China's in vitro diagnosis industry started late, it developed rapidly, and the domestic market competition is becoming increasingly fierce. Throughout the current situation and atmosphere of domestic industrial development, in vitro diagnosis industry has the conditions for scale development. Although at this stage, local in vitro diagnostic enterprises are still facing many difficulties and challenges, driven by relevant national policies and aging population and other factors, in the future, China's in vitro diagnostic industry will have broad development space and rare opportunities, and in vitro diagnostic products will also develop in the direction of automation, integration, convenience, miniaturization, personalization and informatization.   Basic concepts   In vitro diagnosis refers to the process of obtaining clinical diagnosis information by detecting the samples (including blood, body fluid, tissue, etc.) obtained from human body in vitro. The in vitro diagnostic system is composed of the instruments, reagents and consumables needed in the detection process. The enterprises engaged in the R & D, production and marketing of these instruments, reagents and consumables have formed the in vitro diagnostic industry, which integrates biology, medicine, machinery, optics, electronics (Microelectronics), computer, engineering, industrial design and manufacturing and other related technologies.   Different from the international practice, there is no separate concept of IVD in China for a long time, and IVD products have not been defined independently. The products included in the common international concept of IVD have been scattered, and they belong to medical devices, IVD reagents and drugs respectively.   Development status   China's in vitro diagnosis industry started in the 1980s. After 30 years of development, it has the conditions for industrial scale development and is in a critical period of development. China's IVD industry is in a period of rapid development. China's population accounts for one fifth of the world's total population, but China's in vitro diagnosis industry accounts for less than 15% of the global share, and has a broad market space.   In recent years, with the hard work of local IVD enterprises, the level of production technology and product quality have been improved, and the variety of products has become increasingly rich. Domestic IVD equipment and reagents have been gradually accepted by users at home and abroad. The national medical service catalog has standardized the pricing of in vitro diagnosis and other items. IVD reagents are included in the list of charges by item. However, the prices of the products of the international mainstream IVD enterprises are generally 1-5 times higher than those of the domestic similar products, with obvious price disadvantages. This makes the advantages of high cost performance of domestic IVD products in the domestic market, especially in the middle and low-end markets such as secondary hospitals and primary hospitals More competitive.   At present, foreign IVD products (such as Roche, Abbott, etc.) are still dominant in high-end markets such as tertiary hospitals in first tier cities. Other markets have been generally occupied by local IVD enterprises. There is a trend that domestic products have replaced imported ones in some middle and low-end testing markets, which is more significant in terms of in vitro diagnostic testing reagents, especially domestic biochemical reagents. In foreign markets, domestic IVD products have achieved zero breakthrough and developed rapidly, showing a steady growth trend in product types and quality. In addition, from the perspective of market segments, molecular diagnosis and POCT will be the focus of industry development, and will also be the main areas of market competition in the future.   Future direction   In China's development plan, high-performance medical devices, biomedicine and medical informatization have been identified as key breakthrough areas. The market scale of in vitro diagnosis still has great potential. The market demand of in vitro diagnosis will be more diversified, the service mode will be more diversified, and the industry environment will be more standardized and orderly. Technological innovation will become the key to win in the industry. The development trend of in vitro diagnosis industry will present seven trends: systematization, integration, automation, informatization, individualization, miniaturization and convenience.   With the development of society, higher requirements will be put forward for in vitro diagnosis. It is necessary to achieve both rapid detection and consistent with the measurement results of complex technology and large-scale laboratory equipment, so as to strive for valuable time for clinical diagnosis and treatment. Therefore, the "convenience" of equipment is one of the problems that must be considered in in vitro diagnosis. While ensuring the accuracy and traceability of instruments, reagents, calibrators and quality control materials, it is very convenient and fast to use, such as POCT and wearable medical equipment, which will have a good prospect. At the same time, this kind of equipment also has broad application space outside medical institutions (such as home use). In the future, this kind of product will be one of the fastest growing varieties for quite a long time.   Finally, enough attention must be paid to mass spectrometry. At present, mass spectrometry technology has been more mature for microbial identification, small molecule detection, trace element determination, reference method establishment, etc. its unique technical advantages and cheap detection cost will bring unexpected development. In the future, the application of in vitro diagnosis will be beyond imagination.   Desheng biochemical is specialized in R & D, production and sales of vascular additives, in vitro diagnostic reagents, buffers and luminescent substrates. We have a wide range of products and sufficient inventory to provide customers with one-stop purchasing service. Desheng technology will continue to develop and research advanced biochemical reagents to meet the needs of the development of global medical laboratory technology and strive for human health. We hope that through the efforts of all Desheng employees, we can create a world that belongs to Desheng in the in vitro diagnosis industry.

The novel coronavirus infection cases of pneumonia are newly diagnosed every day. The new data of the confirmed and suspected cases and the judgement of the epidemic situation have become the common behavior of people during this Spring Festival holiday. So, how is each new confirmed case confirmed?   The novel coronavirus, influenza virus, hand foot and mouth disease virus and other common virus samples are collected, preserved and transported. Pharyngeal swab, nasal swab or tissue samples of specific parts can be collected, and the stored samples can be used for subsequent clinical trials such as nucleic acid extraction or purification. Virus preservation solution (inactivated) [collection method] 1. Pharyngeal swab: wipe bilateral pharyngeal tonsils and posterior pharyngeal wall with two plastic swabs with polypropylene fiber heads at the same time, immerse the swab head into a tube containing 3ml virus preservation solution (isotonic salt solution, tissue culture solution or phosphate buffer solution can also be used), discard the tail, and tighten the tube cover.   2. Nasal swab: gently insert a plastic rod swab with polypropylene fiber head into the nasal cavity and palate in the nasal meatus, stay for a while, and then slowly rotate to exit. The other side of the nostril was collected with the same method. Immerse the two swabs into the same tube containing 3ml of sampling solution, discard the tail and tighten the tube cover.   3. Nasopharynx extract or respiratory tract extract: extract mucus from nasopharynx or respiratory tract secretion from trachea with collector connected with negative pressure pump. Insert the collector's head into the nasal cavity or trachea, connect the negative pressure, rotate the collector's head and exit slowly, collect the extracted mucus, and flush the collector with 3ml sampling solution once (or connect a pediatric catheter to a 50ml syringe to replace the collector).   [product advantages] The system contains high-efficiency virus lysate, which can inactivate the virus immediately after sampling and effectively prevent the risk of secondary infection.   It contains RNase inhibitor, which can protect the viral nucleic acid from degradation to the maximum extent and greatly improve the efficiency of nucleic acid extraction.   The product can be stored at room temperature for 12 months before sampling, and for one week after sampling. It has good tightness, convenient storage and transportation, and saves transportation cost.   The product is equipped with two sampling rods to improve the sample collection quantity and effectively avoid insufficient sample collection and low concentration sample missing   The 5ml centrifuge tube can avoid the contamination of the pipette during the later sample transfer.

Serum separation gel is a kind of viscous fluid, which contains a lot of hydrogen bonds in its structure. The network structure is formed due to the association of hydrogen bonds. Under the action of centrifugal force, the network structure is destroyed and becomes a fluid with low viscosity. After the centrifugal force disappears, the network structure is formed again and returns to a fluid with high viscosity. This property is called thixotropy.   When the gel and the coagulated blood are centrifuged in the same test tube, the gel forms a gel like isolation layer between the serum and the blood clot to separate the serum and the blood clot. Thus, the yield of serum is improved, the serum is preserved in the original state, the clinical test process is simplified, and the work efficiency is improved.   Nowadays, the raw material of separation gel is polyester or polypropylene. The raw materials of separation gum are polyolefin, polyester and propylene. The accelerators are silica powder, silica carbon and snake venom, which are sprayed on the pipe wall. The separation gel is placed at the bottom of the test tube, injected into the blood sample, and centrifuged in the centrifuge after blood coagulation. The separation gel forms an isolation layer between the serum and the blood clot, and keeps the serum unchanged. The isolation layer adheres to the wall of the test tube tightly, and the serum can be directly absorbed by the automatic analyzer in the original state, or stored in cold storage. Long distance transportation does not affect the test results, and also avoids the influence of fibrin and hemolysis.   In addition, the whole process of blood sample injection into blood collection vessel, serum separation, analyzer direct serum collection, blood sample preservation and waste treatment is carried out in the same branch pipe, so as to avoid blood sample contamination of operators, prevent virus infection in blood, reduce medical waste and improve work efficiency. Therefore, the application of blood separation gel blood vessel in medical examination is indispensable. There are many people who are full of doubts about the need to shake when using the serum separation gel coagulation promoting tube? The answer to this question is yes.   In general, the operation of the gel coagulant tube for serum separation is to gently reverse the blood collection tube immediately after blood collection for 4-5 times to mix the sample. The strength is appropriate and should not be too large. It needs to be placed for 30 minutes to wait for the sample to fully coagulate, the centrifugal radius is 200 Px, the centrifugal speed is maintained at 3500-4000 R / min, and the centrifugal time is 10 minutes. The serum and blood clot are completely separated by the separation gel, and the serum samples can be directly detected on the computer or transferred to the test cup of the instrument.   Desheng has 15 years of rich experience in R & D and production of blood vessel additives, and has formed independent intellectual property rights and professional production and R & D capacity in the aspect of blood vessel additives. To provide products and raw material solutions for more than 100 domestic and foreign manufacturers. The serum separation gel produced by Desheng is radiation resistant, and is specially used to manufacture disposable vacuum blood collection vessel and injection blood collection vessel. It is a necessary material for the preservation, transfer and transfer of high-quality serum and blood samples in clinical examination.

Serum separation glue is mainly composed of macromolecular hydrocarbons and hydrophobic glue. As a kind of macromolecular polymer, it is insoluble in water and inert. It is a thixotropic viscose liquid with a density of 1.04-1.05 mmol / L. it has the advantages of oxidation resistance, high temperature resistance, low temperature resistance and good gas tightness.   The reason why serum separation gel can separate serum and blood cells is that the density of serum is 1.026-1.031 mmolgl, while the density of blood cells is 1.090-1.095. Due to the specific gravity, the separation gel is just between serum and blood cells, so generally, after blood centrifugation, there are three layers of serum, separation gel and blood cells in turn. There are two kinds of commonly used separation gel collecting vessels in laboratory: serum separation gel coagulant promoting tube and plasma separation gel anticoagulant tube. Serum separation gel coagulant tube is to add coagulant to the blood collection vessel to shorten the blood coagulation time, quickly get the serum, and report the results in the shortest time. There is no need to add coagulant in the glass collecting vessel, blood contact with the glass tube wall will trigger coagulation. When factor XI and factor Ⅻ contact plastic blood collection vessel, their activation ability is very weak, so coagulants need to be added to shorten the coagulation time. Plasma separation gel anticoagulant tube is sprayed with heparin lithium and other anticoagulants on the inner wall of separation gel blood vessel to meet the needs of rapid plasma biochemical emergency test.   At present, the serum separation gel has been widely used in clinical laboratory. The separation gel can form an isolation layer between cell components and serum (plasma), effectively prevent the material exchange between blood cells and serum (plasma), and ensure the stability of serum (plasma) components in a certain period of time. In the clinical application of separation gel, many non-standard operations will affect the separation effect, and some separation gel can be used The blood collection vessel interfered with some test items. These problems are not easy to be found in daily quality control and routine testing. In order to ensure the authenticity of the test results, it is very important to do a good job in the quality control of blood samples before testing.   Desheng is a high-quality manufacturer specializing in the production of serum separation gel. In addition to striving to improve the quality, it is also committed to providing laboratory personnel with a set of clinical blood sample solutions, that is, operation specifications in the process of blood collection, transportation, storage, blood collection and centrifugation, so as to truly achieve first-class quality and service.

With the repeated reversal of the epidemic situation, anti epidemic has become the primary concern of human beings. We should not only prevent the spread of the epidemic, but also protect our own safety, especially the staff who collect virus samples. If the virus is not collected, it is likely to be infected. Therefore, in such a severe test, the emergence of disposable virus preservation tube greatly reduces the risk of infection and ensures the safety of our front-line personnel. Disposable virus storage tube   Methods of specimen collection 1. Pharyngeal swab: wipe bilateral pharyngeal tonsils and posterior pharyngeal wall with two plastic swabs with polypropylene fiber heads at the same time, immerse the swab head into a tube containing 3ml virus preservation solution (isotonic salt solution, tissue culture solution or phosphate buffer solution can also be used), discard the tail, and tighten the tube cover.   2. Nasal swab: gently insert a plastic rod swab with polypropylene fiber head into the nasal cavity and palate in the nasal meatus, stay for a while, and then slowly rotate to exit. The other side of the nostril was collected with the same method. Immerse the two swabs into the same tube containing 3ml of sampling solution, discard the tail and tighten the tube cover.   3. On the label of PE pipe, write down the type of sample, sampling time, number and name of patient with oil marker.   4. After the collection, put the disposable virus storage tube into the special transport box (or vaccine transport box), put it into the ice cube, and then fill it with soft material and seal it. It should be transported by special person instead of mail. It is better to use the special vehicle.   5. If the collected specimens cannot be delivered within 24 hours, they should be stored below - 70 ℃ as soon as possible. If there is no - 70 ℃ condition, it should be stored in the refrigerator at 4 ℃ for a short time, and the specimen should be delivered as soon as possible.   6. Influenza virus is unstable from - 20 ℃ to - 40 ℃, so it is best to keep it below - 70 ℃ for a long time.   In this case, it greatly protects us, and at the same time, it also protects the virus from failure after degradation, resulting in false negative. Disposable virus preservation tube is a hero in the protection of the epidemic. Desheng biochemical company specializes in VTM and some products. If you need, please contact us!